| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yu Jia, Nian Gong, Teng-Fei Li, Bin Zhu, Yong-Xiang Wan. Peptidic exenatide and herbal catalpol mediate neuroprotection via the hippocampal GLP-1 receptor/β-endorphin pathway. Pharmacological research. vol 102. 2016-09-20. PMID:26546042. |
the rat middle cerebral artery occlusion model was employed, and the glp-1r immunofluorescence staining and β-endorphin measurement were assayed in the hippocampus and primary cultures of microglia, neurons and astrocytes. |
2016-09-20 |
2023-08-13 |
rat |
| Yu Jia, Nian Gong, Teng-Fei Li, Bin Zhu, Yong-Xiang Wan. Peptidic exenatide and herbal catalpol mediate neuroprotection via the hippocampal GLP-1 receptor/β-endorphin pathway. Pharmacological research. vol 102. 2016-09-20. PMID:26546042. |
the immunoreactivity of glp-1rs on microglia in the hippocampus was upregulated after ischemia reperfusion. |
2016-09-20 |
2023-08-13 |
rat |
| Yu Jia, Nian Gong, Teng-Fei Li, Bin Zhu, Yong-Xiang Wan. Peptidic exenatide and herbal catalpol mediate neuroprotection via the hippocampal GLP-1 receptor/β-endorphin pathway. Pharmacological research. vol 102. 2016-09-20. PMID:26546042. |
injection of exenatide and catalpol significantly stimulated β-endorphin expression in the hippocampus and cultured primary microglia (but not primary neurons or astrocytes). |
2016-09-20 |
2023-08-13 |
rat |
| Yu Jia, Nian Gong, Teng-Fei Li, Bin Zhu, Yong-Xiang Wan. Peptidic exenatide and herbal catalpol mediate neuroprotection via the hippocampal GLP-1 receptor/β-endorphin pathway. Pharmacological research. vol 102. 2016-09-20. PMID:26546042. |
our results indicate, for the first time, that the neuroprotective effects of catalpol and exenatide are glp-1r-specific, and that these effects are mediated by β-endorphin expression probably in hippocampal microglia. |
2016-09-20 |
2023-08-13 |
rat |
| Taito Matsuda, Kinichi Nakashim. Bidirectional communication between the innate immune and nervous systems for homeostatic neurogenesis in the adult hippocampus. Neurogenesis (Austin, Tex.). vol 2. issue 1. 2016-09-08. PMID:27604264. |
recently, we have discovered that microglia, the major immune cells in the brain, attenuate seizure-induced aberrant hippocampal neurogenesis to withstand cognitive decline and recurrent seizure. |
2016-09-08 |
2023-08-13 |
Not clear |
| Satya Narayan Deep, Iswar Baitharu, Apurva Sharma, Anoop Kishor Singh Gurjar, Dipti Prasad, Shashi Bala Sing. Neuroprotective Role of L-NG-Nitroarginine Methyl Ester (L-NAME) against Chronic Hypobaric Hypoxia with Crowding Stress (CHC) Induced Depression-Like Behaviour. PloS one. vol 11. issue 4. 2016-08-29. PMID:27082990. |
the inhibition of no synthesis by l-name during chc exposure decreased the number of active microglia in hippocampus as evident from decreased iba-1 positive cells. |
2016-08-29 |
2023-08-13 |
rat |
| Marie-Caroline Cotel, Ewelina M Lenartowicz, Sridhar Natesan, Michel M Modo, Jonathan D Cooper, Steven C R Williams, Shitij Kapur, Anthony C Verno. Microglial activation in the rat brain following chronic antipsychotic treatment at clinically relevant doses. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 25. issue 11. 2016-08-26. PMID:26321204. |
chronic apd treatment resulted in increased density of total microglia in the hippocampus, striatum, and somatosensory cortex, but not in the acc. |
2016-08-26 |
2023-08-13 |
rat |
| Daniel B McKim, Anzela Niraula, Andrew J Tarr, Eric S Wohleb, John F Sheridan, Jonathan P Godbou. Neuroinflammatory Dynamics Underlie Memory Impairments after Repeated Social Defeat. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 9. 2016-08-16. PMID:26937001. |
here, we show that rsd promoted hippocampal neuroinflammatory activation that was characterized by proinflammatory gene expression and by microglia activation and monocyte trafficking that was particularly pronounced within the caudal extent of the hippocampus. |
2016-08-16 |
2023-08-13 |
Not clear |
| Yuan Shao, Hui Peng, Qingjun Huang, Jiming Kong, Haiyun X. Quetiapine mitigates the neuroinflammation and oligodendrocyte loss in the brain of C57BL/6 mouse following cuprizone exposure for one week. European journal of pharmacology. vol 765. 2016-08-12. PMID:26321148. |
mice in the ns+cpz group showed fewer ols, more activated astrocytes and microglia with higher immunofluorescence intensity in the examined brain regions of the corpus callosum, caudate putamen, cerebral cortex, and hippocampus. |
2016-08-12 |
2023-08-13 |
mouse |
| Sabine Hellwig, Annette Masuch, Sigrun Nestel, Natalie Katzmarski, Melanie Meyer-Luehmann, Knut Bibe. Forebrain microglia from wild-type but not adult 5xFAD mice prevent amyloid-β plaque formation in organotypic hippocampal slice cultures. Scientific reports. vol 5. 2016-08-08. PMID:26416689. |
forebrain microglia from wild-type but not adult 5xfad mice prevent amyloid-β plaque formation in organotypic hippocampal slice cultures. |
2016-08-08 |
2023-08-13 |
mouse |
| Sabine Hellwig, Annette Masuch, Sigrun Nestel, Natalie Katzmarski, Melanie Meyer-Luehmann, Knut Bibe. Forebrain microglia from wild-type but not adult 5xFAD mice prevent amyloid-β plaque formation in organotypic hippocampal slice cultures. Scientific reports. vol 5. 2016-08-08. PMID:26416689. |
in the present study, an organotypic hippocampal slice culture (ohsc) system with an in vivo-like microglial-neuronal environment was used to investigate the potential contribution of microglia to aβ plaque formation. |
2016-08-08 |
2023-08-13 |
mouse |
| C G Diniz, N G M Magalhães, A A Sousa, C Santos Filho, D G Diniz, C M Lima, M A Oliveira, D C Paulo, P D C Pereira, D F Sherry, C W Picanço-Dini. Microglia and neurons in the hippocampus of migratory sandpipers. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 49. issue 1. 2016-08-08. PMID:26577847. |
microglia and neurons in the hippocampus of migratory sandpipers. |
2016-08-08 |
2023-08-13 |
Not clear |
| C G Diniz, N G M Magalhães, A A Sousa, C Santos Filho, D G Diniz, C M Lima, M A Oliveira, D C Paulo, P D C Pereira, D F Sherry, C W Picanço-Dini. Microglia and neurons in the hippocampus of migratory sandpipers. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 49. issue 1. 2016-08-08. PMID:26577847. |
a. macularia did not differ from c. pusilla in the total number of hippocampal neurons, but the species had a larger hippocampal formation and more hippocampal microglia. |
2016-08-08 |
2023-08-13 |
Not clear |
| Barbara Klein, Heike Mrowetz, Josef Thalhamer, Sandra Scheiblhofer, Richard Weiss, Ludwig Aigne. Allergy Enhances Neurogenesis and Modulates Microglial Activation in the Hippocampus. Frontiers in cellular neuroscience. vol 10. 2016-07-22. PMID:27445696. |
the focus of the present study was on microglia, the resident immune cells of the cns, and on hippocampal neurogenesis, i.e., the generation of new neurons. |
2016-07-22 |
2023-08-13 |
mouse |
| Barbara Klein, Heike Mrowetz, Josef Thalhamer, Sandra Scheiblhofer, Richard Weiss, Ludwig Aigne. Allergy Enhances Neurogenesis and Modulates Microglial Activation in the Hippocampus. Frontiers in cellular neuroscience. vol 10. 2016-07-22. PMID:27445696. |
surprisingly, fewer iba1(+) microglia were found in the granular layer (gl) and subgranular zone (sgz) of the hippocampal dentate gyrus and also the number of iba1(+)mhcii(+) cells was lower, indicating a reduced microglial surveillance and activation in the hippocampus of allergic mice. |
2016-07-22 |
2023-08-13 |
mouse |
| Barbara Klein, Heike Mrowetz, Josef Thalhamer, Sandra Scheiblhofer, Richard Weiss, Ludwig Aigne. Allergy Enhances Neurogenesis and Modulates Microglial Activation in the Hippocampus. Frontiers in cellular neuroscience. vol 10. 2016-07-22. PMID:27445696. |
in summary, allergy led to a reduced microglia presence and activity and to an elevated level of neurogenesis in the hippocampus. |
2016-07-22 |
2023-08-13 |
mouse |
| Michael J Vasek, Charise Garber, Denise Dorsey, Douglas M Durrant, Bryan Bollman, Allison Soung, Jinsheng Yu, Carlos Perez-Torres, Arnaud Frouin, Daniel K Wilton, Kristen Funk, Bette K DeMasters, Xiaoping Jiang, James R Bowen, Steven Mennerick, John K Robinson, Joel R Garbow, Kenneth L Tyler, Mehul S Suthar, Robert E Schmidt, Beth Stevens, Robyn S Klei. A complement-microglial axis drives synapse loss during virus-induced memory impairment. Nature. vol 534. issue 7608. 2016-07-20. PMID:27337340. |
wnv-ns5-e218a-recovered mice (recovery defined as survival after acute infection) display impaired spatial learning and persistence of phagocytic microglia without loss of hippocampal neurons or volume. |
2016-07-20 |
2023-08-13 |
mouse |
| Takashi Umekawa, Ahmed M Osman, Wei Han, Tomoaki Ikeda, Klas Blomgre. Resident microglia, rather than blood-derived macrophages, contribute to the earlier and more pronounced inflammatory reaction in the immature compared with the adult hippocampus after hypoxia-ischemia. Glia. vol 63. issue 12. 2016-07-19. PMID:26179283. |
resident microglia, rather than blood-derived macrophages, contribute to the earlier and more pronounced inflammatory reaction in the immature compared with the adult hippocampus after hypoxia-ischemia. |
2016-07-19 |
2023-08-13 |
mouse |
| Takashi Umekawa, Ahmed M Osman, Wei Han, Tomoaki Ikeda, Klas Blomgre. Resident microglia, rather than blood-derived macrophages, contribute to the earlier and more pronounced inflammatory reaction in the immature compared with the adult hippocampus after hypoxia-ischemia. Glia. vol 63. issue 12. 2016-07-19. PMID:26179283. |
the purpose of this study was to phenotype resident microglia and blood-derived macrophages in the hippocampus after hi in neonatal (postnatal day 9, p9) or adult (3 months of age, 3mo) mice. |
2016-07-19 |
2023-08-13 |
mouse |
| Takashi Umekawa, Ahmed M Osman, Wei Han, Tomoaki Ikeda, Klas Blomgre. Resident microglia, rather than blood-derived macrophages, contribute to the earlier and more pronounced inflammatory reaction in the immature compared with the adult hippocampus after hypoxia-ischemia. Glia. vol 63. issue 12. 2016-07-19. PMID:26179283. |
resident microglia (cx3cr1-gfp+) proliferated and were activated earlier after hi in the p9 (1-3 days) than that in the 3mo hippocampus, but remained longer in the adult brain (3-7 days). |
2016-07-19 |
2023-08-13 |
mouse |