| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Giovanoli, H Engler, A Engler, J Richetto, J Feldon, M A Riva, M Schedlowski, U Meye. Preventive effects of minocycline in a neurodevelopmental two-hit model with relevance to schizophrenia. Translational psychiatry. vol 6. 2017-02-06. PMID:27045842. |
in addition, the pharmacological intervention blocked hippocampal and prefrontal microglia activation and interleukin-1β expression in offspring exposed to prenatal infection and peripubertal stress. |
2017-02-06 |
2023-08-13 |
mouse |
| Megan M Muccigrosso, Joni Ford, Brooke Benner, Daniel Moussa, Christopher Burnsides, Ashley M Fenn, Phillip G Popovich, Jonathan Lifshitz, Fredrick Rohan Walker, Daniel S Eiferman, Jonathan P Godbou. Cognitive deficits develop 1month after diffuse brain injury and are exaggerated by microglia-associated reactivity to peripheral immune challenge. Brain, behavior, and immunity. vol 54. 2017-02-01. PMID:26774527. |
these deficits were associated with exaggerated microglia-mediated inflammation with amplified (il-1β, ccl2, tnfα) and prolonged (tnfα) cytokine/chemokine expression, and a marked reactive morphological profile of microglia in the ca3 of the hippocampus. |
2017-02-01 |
2023-08-13 |
mouse |
| Peng Ji, Kyle M Schachtschneider, Lawrence B Schook, Frederick R Walker, Rodney W Johnso. Peripheral viral infection induced microglial sensome genes and enhanced microglial cell activity in the hippocampus of neonatal piglets. Brain, behavior, and immunity. vol 54. 2017-02-01. PMID:26872419. |
peripheral viral infection induced microglial sensome genes and enhanced microglial cell activity in the hippocampus of neonatal piglets. |
2017-02-01 |
2023-08-13 |
Not clear |
| Peng Ji, Kyle M Schachtschneider, Lawrence B Schook, Frederick R Walker, Rodney W Johnso. Peripheral viral infection induced microglial sensome genes and enhanced microglial cell activity in the hippocampus of neonatal piglets. Brain, behavior, and immunity. vol 54. 2017-02-01. PMID:26872419. |
to investigate this, we assessed gene expression in hippocampal tissue obtained from a previously published study reporting increased microglial cell activity and reduced hippocampal-dependent learning in neonatal piglets infected with porcine reproductive and respiratory syndrome virus (prrsv), a virus that induces interstitial pneumonia. |
2017-02-01 |
2023-08-13 |
Not clear |
| Peng Ji, Kyle M Schachtschneider, Lawrence B Schook, Frederick R Walker, Rodney W Johnso. Peripheral viral infection induced microglial sensome genes and enhanced microglial cell activity in the hippocampus of neonatal piglets. Brain, behavior, and immunity. vol 54. 2017-02-01. PMID:26872419. |
as the sensome may foretell microglia reactivity, we next inoculated piglets with culture medium or prrsv at pd 7 and assessed hippocampal microglia morphology and function at pd 28 when signs of infection were waning. |
2017-02-01 |
2023-08-13 |
Not clear |
| Peng Ji, Kyle M Schachtschneider, Lawrence B Schook, Frederick R Walker, Rodney W Johnso. Peripheral viral infection induced microglial sensome genes and enhanced microglial cell activity in the hippocampus of neonatal piglets. Brain, behavior, and immunity. vol 54. 2017-02-01. PMID:26872419. |
bipolar rod-like microglia not evident in hippocampus of control piglets, were present in infected piglets. |
2017-02-01 |
2023-08-13 |
Not clear |
| Miguel Ángel Ontiveros-Torres, María Luisa Labra-Barrios, Sofía Díaz-Cintra, Azucena Ruth Aguilar-Vázquez, Samadhi Moreno-Campuzano, Paola Flores-Rodríguez, Claudia Luna-Herrera, Raúl Mena, George Perry, Benjamín Florán-Garduño, José Luna-Muñoz, Juan Pedro Luna-Aria. Fibrillar Amyloid-β Accumulation Triggers an Inflammatory Mechanism Leading to Hyperphosphorylation of the Carboxyl-Terminal End of Tau Polypeptide in the Hippocampal Formation of the 3×Tg-AD Transgenic Mouse. Journal of Alzheimer's disease : JAD. vol 52. issue 1. 2017-01-27. PMID:27031470. |
our results indicate that the presence of fibrillar aβ deposits correlates with a significant activation of astrocytes and microglia in subiculum and ca1 regions of hippocampus. |
2017-01-27 |
2023-08-13 |
mouse |
| Li-Li Qiu, Mu-Huo Ji, Hui Zhang, Jiao-Jiao Yang, Xiao-Ru Sun, Hui Tang, Jing Wang, Wen-Xue Liu, Jian-Jun Yan. NADPH oxidase 2-derived reactive oxygen species in the hippocampus might contribute to microglial activation in postoperative cognitive dysfunction in aged mice. Brain, behavior, and immunity. vol 51. 2017-01-10. PMID:26254234. |
together, our data suggested that nox2-derived ros in hippocampal microglia, at least in part, contributes to subsequent neuroinflammation and cognitive impairments induced by surgery in aged mice. |
2017-01-10 |
2023-08-13 |
mouse |
| Shuai Hao, Aditi Dey, Xiaolin Yu, Alexis M Stranaha. Dietary obesity reversibly induces synaptic stripping by microglia and impairs hippocampal plasticity. Brain, behavior, and immunity. vol 51. 2017-01-10. PMID:26336035. |
dietary obesity reversibly induces synaptic stripping by microglia and impairs hippocampal plasticity. |
2017-01-10 |
2023-08-13 |
mouse |
| Shuai Hao, Aditi Dey, Xiaolin Yu, Alexis M Stranaha. Dietary obesity reversibly induces synaptic stripping by microglia and impairs hippocampal plasticity. Brain, behavior, and immunity. vol 51. 2017-01-10. PMID:26336035. |
dietary obesity impaired hippocampus-dependent memory, reduced long-term potentiation (ltp), and induced expression of the activation marker major histocompatibility complex ii (mhcii) in hippocampal microglia. |
2017-01-10 |
2023-08-13 |
mouse |
| Shuai Hao, Aditi Dey, Xiaolin Yu, Alexis M Stranaha. Dietary obesity reversibly induces synaptic stripping by microglia and impairs hippocampal plasticity. Brain, behavior, and immunity. vol 51. 2017-01-10. PMID:26336035. |
taken together, these findings indicate that dietary obesity reversibly impairs hippocampal function, and that deficits may be attributable to synaptic stripping by microglia. |
2017-01-10 |
2023-08-13 |
mouse |
| X Chen, L Rivard, S Naqvi, S Nakada, J F Padbury, J Sanchez-Esteban, E G Stopa, Y-P Lim, B S Stonestree. Expression and localization of Inter-alpha Inhibitors in rodent brain. Neuroscience. vol 324. 2017-01-10. PMID:26964679. |
immunoreactivity was found in neurons, microglia, astrocytes and oligodendroglia in multiple brain regions including cortex and hippocampus, as well as within both the ependyma and choroid plexus. |
2017-01-10 |
2023-08-13 |
mouse |
| Jorge Valero, Iñaki Paris, Amanda Sierr. Lifestyle Shapes the Dialogue between Environment, Microglia, and Adult Neurogenesis. ACS chemical neuroscience. vol 7. issue 4. 2017-01-06. PMID:26971802. |
here, we review the current knowledge about the dialogue maintained between microglia and the hippocampal neurogenic cascade. |
2017-01-06 |
2023-08-13 |
Not clear |
| Jorge Valero, Iñaki Paris, Amanda Sierr. Lifestyle Shapes the Dialogue between Environment, Microglia, and Adult Neurogenesis. ACS chemical neuroscience. vol 7. issue 4. 2017-01-06. PMID:26971802. |
understanding how the communication between microglia and hippocampal neurogenesis is affected by lifestyle choices is crucial to maintain the brain cognitive reserve and prevent the maladaptive responses that emerge during disease or injury through adulthood and aging. |
2017-01-06 |
2023-08-13 |
Not clear |
| Junming Fan, Xiaofang Fan, Yang Li, Jinbin Guo, Dongmei Xia, Lu Ding, Qingqing Zheng, Wei Wang, Feng Xue, Ran Chen, Shouting Liu, Lianggang Hu, Yongsheng Gon. Blunted inflammation mediated by NF-κB activation in hippocampus alleviates chronic normobaric hypoxia-induced anxiety-like behavior in rats. Brain research bulletin. vol 122. 2017-01-05. PMID:26972056. |
in addition, cnh treatment significantly increased iba-1, inos, cox-2, and p-pka in hippocampus, which were blocked by pdtc pretreatment, suggesting cnh may activate microglia cells in hippocampus through nf-κb pathway. |
2017-01-05 |
2023-08-13 |
rat |
| Junming Fan, Xiaofang Fan, Yang Li, Jinbin Guo, Dongmei Xia, Lu Ding, Qingqing Zheng, Wei Wang, Feng Xue, Ran Chen, Shouting Liu, Lianggang Hu, Yongsheng Gon. Blunted inflammation mediated by NF-κB activation in hippocampus alleviates chronic normobaric hypoxia-induced anxiety-like behavior in rats. Brain research bulletin. vol 122. 2017-01-05. PMID:26972056. |
in conclusion, our results illustrate a mechanism that, activation of nf-κb in hippocampus may trigger the proinflammatory response of microglia cells, and inos-pka pathway may involve in anxiogenic effect in cnh exposed rats. |
2017-01-05 |
2023-08-13 |
rat |
| Fangfang Qi, Junhua Yang, Yucen Xia, Qunfang Yuan, Kaihua Guo, Juntao Zou, Zhibin Ya. A(H1N1) vaccination recruits T lymphocytes to the choroid plexus for the promotion of hippocampal neurogenesis and working memory in pregnant mice. Brain, behavior, and immunity. vol 53. 2017-01-03. PMID:26576725. |
furthermore, aiv vaccination caused microglia to skew toward an m2-like phenotype (increased arginase-1 and ym1 mrna levels), and elevated levels of brain-derived growth factor (bdnf) and insulin-like growth factor-1 (igf-1) were found in the hippocampus, whereas these effects were offset by anti-tcr antibody treatment. |
2017-01-03 |
2023-08-13 |
mouse |
| K E Boschen, M J Ruggiero, A Y Klintsov. Neonatal binge alcohol exposure increases microglial activation in the developing rat hippocampus. Neuroscience. vol 324. 2017-01-03. PMID:26996510. |
on pd10, microglial cell counts and area of cell territory were assessed using unbiased stereology in the hippocampal subfields ca1, ca3 and dentate gyrus (dg), and hippocampal expression of pro- and anti-inflammatory genes was analyzed. |
2017-01-03 |
2023-08-13 |
rat |
| K E Boschen, M J Ruggiero, A Y Klintsov. Neonatal binge alcohol exposure increases microglial activation in the developing rat hippocampus. Neuroscience. vol 324. 2017-01-03. PMID:26996510. |
in summary, the number and activation of microglia in the neonatal hippocampus are both affected in a rat model of fasd, along with increased gene expression of pro- and anti-inflammatory cytokines. |
2017-01-03 |
2023-08-13 |
rat |
| Yuka Kasahara, Ryuta Koyama, Yuji Ikegay. Depth and time-dependent heterogeneity of microglia in mouse hippocampal slice cultures. Neuroscience research. vol 111. 2016-12-29. PMID:27211829. |
depth and time-dependent heterogeneity of microglia in mouse hippocampal slice cultures. |
2016-12-29 |
2023-08-13 |
mouse |