| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Irena Balzekas, Jose Hernandez, Jacob White, Sookyong Ko. Confounding effect of EEG implantation surgery: Inadequacy of surgical control in a two hit model of temporal lobe epilepsy. Neuroscience letters. vol 622. 2017-07-19. PMID:27095588. |
hippocampal microglia activation, as demonstrated by percent area gfp signal and gfp positive cell counts, prior to seizures was indistinguishable between electrode-implanted mice and controls, but was significantly greater in electrode-implanted mice following seizures. |
2017-07-19 |
2023-08-13 |
mouse |
| Nutchareeporn Nillert, Wanassanun Pannangrong, Jariya Umka Welbat, Wunnee Chaijaroonkhanarak, Kittisak Sripanidkulchai, Bungorn Sripanidkulcha. Neuroprotective Effects of Aged Garlic Extract on Cognitive Dysfunction and Neuroinflammation Induced by β-Amyloid in Rats. Nutrients. vol 9. issue 1. 2017-07-13. PMID:28054940. |
then the rats were sacrificed to investigate the alteration of microglia cells, il-1β and tnfα in the cerebral cortex and hippocampus. |
2017-07-13 |
2023-08-13 |
rat |
| Ke Pan, Xiaojun Li, Yan Chen, Dan Zhu, Yuping Li, Guocai Tao, Zhiyi Zu. Deferoxamine pre-treatment protects against postoperative cognitive dysfunction of aged rats by depressing microglial activation via ameliorating iron accumulation in hippocampus. Neuropharmacology. vol 111. 2017-07-11. PMID:27608977. |
furthermore, deferoxamine sharply reduced the hippocampal reactive oxygen species, malondialdehyde concentration and ox-42 that is a marker of microglia, which might reduce postoperative brain cell apoptosis. |
2017-07-11 |
2023-08-13 |
rat |
| Ya-Juan Zhu, Ke Peng, Xiao-Wen Meng, Fu-Hai J. Attenuation of neuroinflammation by dexmedetomidine is associated with activation of a cholinergic anti-inflammatory pathway in a rat tibial fracture model. Brain research. vol 1644. 2017-06-29. PMID:27163720. |
dexmedetomidine pretreatment significantly suppressed the inflammatory responses, as evidenced by lower tnf-α and il-1β levels, significantly inhibited nf-κb activity, and alleviated overexpression of microglia and astrocytes in the hippocampus. |
2017-06-29 |
2023-08-13 |
rat |
| Andrew D Kraft, Christopher A McPherson, G Jean Harr. Association Between Microglia, Inflammatory Factors, and Complement with Loss of Hippocampal Mossy Fiber Synapses Induced by Trimethyltin. Neurotoxicity research. vol 30. issue 1. 2017-06-26. PMID:26892644. |
association between microglia, inflammatory factors, and complement with loss of hippocampal mossy fiber synapses induced by trimethyltin. |
2017-06-26 |
2023-08-13 |
mouse |
| Oihane Abiega, Sol Beccari, Irune Diaz-Aparicio, Agnes Nadjar, Sophie Layé, Quentin Leyrolle, Diego Gómez-Nicola, María Domercq, Alberto Pérez-Samartín, Víctor Sánchez-Zafra, Iñaki Paris, Jorge Valero, Julie C Savage, Chin-Wai Hui, Marie-Ève Tremblay, Juan J P Deudero, Amy L Brewster, Anne E Anderson, Laura Zaldumbide, Lara Galbarriatu, Ainhoa Marinas, Maria dM Vivanco, Carlos Matute, Mirjana Maletic-Savatic, Juan M Encinas, Amanda Sierr. Neuronal Hyperactivity Disturbs ATP Microgradients, Impairs Microglial Motility, and Reduces Phagocytic Receptor Expression Triggering Apoptosis/Microglial Phagocytosis Uncoupling. PLoS biology. vol 14. issue 5. 2017-06-21. PMID:27228556. |
recent findings suggest that in the adult hippocampal neurogenic niche, where the excess of newborn cells undergo apoptosis in physiological conditions, phagocytosis is efficiently executed by surveillant, ramified microglia. |
2017-06-21 |
2023-08-13 |
mouse |
| Laura Baroncelli, Angelo Molinaro, Francesco Cacciante, Maria Grazia Alessandrì, Debora Napoli, Elena Putignano, Jonida Tola, Vincenzo Leuzzi, Giovanni Cioni, Tommaso Pizzoruss. A mouse model for creatine transporter deficiency reveals early onset cognitive impairment and neuropathology associated with brain aging. Human molecular genetics. vol 25. issue 19. 2017-06-09. PMID:27466184. |
pathological examination showed a prominent loss of gabaergic synapses, marked activation of microglia, reduction of hippocampal neurogenesis and the accumulation of autofluorescent lipofuscin. |
2017-06-09 |
2023-08-13 |
mouse |
| Michelle Go, Jinghong Kou, Jeong-Eun Lim, Junling Yang, Ken-Ichiro Fukuch. Microglial response to LPS increases in wild-type mice during aging but diminishes in an Alzheimer's mouse model: Implication of TLR4 signaling in disease progression. Biochemical and biophysical research communications. vol 479. issue 2. 2017-06-06. PMID:27641666. |
in contrast, at 12 months of age, iba1 immunoreactivity of microglia was increased 541-fold and 38-fold in the neocortex and hippocampus, respectively, in lps-injected non-tg mice and 2.7-fold and 3.3-fold in the neocortex and hippocampus, respectively, in lps-injected tgapp/ps1 mice. |
2017-06-06 |
2023-08-13 |
mouse |
| Hye-Sun Lim, Ohn-Soon Kim, Bu-Yeo Kim, Soo-Jin Jeon. Apigetrin from Scutellaria baicalensis Georgi Inhibits Neuroinflammation in BV-2 Microglia and Exerts Neuroprotective Effect in HT22 Hippocampal Cells. Journal of medicinal food. vol 19. issue 11. 2017-05-26. PMID:27845861. |
apigetrin from scutellaria baicalensis georgi inhibits neuroinflammation in bv-2 microglia and exerts neuroprotective effect in ht22 hippocampal cells. |
2017-05-26 |
2023-08-13 |
mouse |
| Martin Pohland, Robert Glumm, Frank Wiekhorst, Jürgen Kiwit, Jana Glum. Biocompatibility of very small superparamagnetic iron oxide nanoparticles in murine organotypic hippocampal slice cultures and the role of microglia. International journal of nanomedicine. vol 12. 2017-05-08. PMID:28280327. |
biocompatibility of very small superparamagnetic iron oxide nanoparticles in murine organotypic hippocampal slice cultures and the role of microglia. |
2017-05-08 |
2023-08-13 |
Not clear |
| Gudrun Schlegel, Ralf Scholz, Kurt Ullrich, René Santer, Gabriele M Run. Phenylketonuria: Direct and indirect effects of phenylalanine. Experimental neurology. vol 281. 2017-05-01. PMID:27091224. |
microglia activity and c3 complement expression, both of which were reduced in the pah(enu2) mouse, however, were unaffected in hippocampal cultures treated with phenylalanine. |
2017-05-01 |
2023-08-13 |
mouse |
| Ha-Jin Pak, Tae-Ryong Riew, Yoo-Jin Shin, Jeong-Heon Choi, Xuyan Jin, Mun-Yong Le. Enhanced expression of the calcium-sensing receptor in reactive astrocytes following ischemic injury in vivo and in vitro. Journal of the neurological sciences. vol 366. 2017-04-25. PMID:27288786. |
casr was constitutively expressed in neurons of the pyramidal and granule cell layers, whereas increased casr immunoreactivity was observed in reactive astrocytes, but not in activated microglia or macrophages, in the ca1 region of the post-ischemic hippocampus. |
2017-04-25 |
2023-08-13 |
rat |
| Yu Jin Kim, Hye-Sun Lim, Jun Lee, Soo-Jin Jeon. Quantitative Analysis of Psoralea corylifolia Linne and its Neuroprotective and Anti-Neuroinflammatory Effects in HT22 Hippocampal Cells and BV-2 Microglia. Molecules (Basel, Switzerland). vol 21. issue 8. 2017-04-14. PMID:27548120. |
quantitative analysis of psoralea corylifolia linne and its neuroprotective and anti-neuroinflammatory effects in ht22 hippocampal cells and bv-2 microglia. |
2017-04-14 |
2023-08-13 |
Not clear |
| Yu Jin Kim, Hye-Sun Lim, Jun Lee, Soo-Jin Jeon. Quantitative Analysis of Psoralea corylifolia Linne and its Neuroprotective and Anti-Neuroinflammatory Effects in HT22 Hippocampal Cells and BV-2 Microglia. Molecules (Basel, Switzerland). vol 21. issue 8. 2017-04-14. PMID:27548120. |
we also investigated the neuroprotective and anti-neuroinflammation effects of p. corylifolia and its standard components in the hippocampal cell line ht22 and microglia cell line bv-2. |
2017-04-14 |
2023-08-13 |
Not clear |
| Susan Cohen, Xingrao Ke, Qiuli Liu, Qi Fu, Amber Majnik, Robert Lan. Adverse early life environment increases hippocampal microglia abundance in conjunction with decreased neural stem cells in juvenile mice. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 55. 2017-03-28. PMID:27666383. |
adverse early life environment increases hippocampal microglia abundance in conjunction with decreased neural stem cells in juvenile mice. |
2017-03-28 |
2023-08-13 |
mouse |
| Bo Chen, Xiaoyuan Deng, Bin Wang, Hongliang Li. Etanercept, an inhibitor of TNF-a, prevents propofol-induced neurotoxicity in the developing brain. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 55. 2017-03-28. PMID:27756568. |
furthermore, mtnf-α (precursor of tnf-α) expression in microglia cells is increased after propofol anaesthesia in either the hippocampus or pfc, but mtnf-α expression in neurons is only increased in the pfc. |
2017-03-28 |
2023-08-13 |
rat |
| Shuangxi Liu, Yan Gao, Xiaoli Yu, Baoming Zhao, Lu Liu, Yin Zhao, Zhenzhao Luo, Jing Sh. Annexin-1 Mediates Microglial Activation and Migration via the CK2 Pathway during Oxygen-Glucose Deprivation/Reperfusion. International journal of molecular sciences. vol 17. issue 10. 2017-03-23. PMID:27782092. |
in rat hippocampal slices, ogd/r treatment enhanced the anxa1 expression in neuron, the formyl peptide receptor (fprs) expression in microglia, and the microglial activation in the ca1 region (cornu ammonis 1). |
2017-03-23 |
2023-08-13 |
rat |
| Eun Jeong Sohn, Min Jea Shin, Won Sik Eum, Dae Won Kim, Ji In Yong, Eun Ji Ryu, Jung Hwan Park, Su Bin Cho, Hyun Ju Cha, Sang Jin Kim, Hyeon Ji Yeo, Eun Ji Yeo, Yeon Joo Choi, Seung Kwon Im, Hae Young Kweon, Duk-Soo Kim, Yeon Hee Yu, Sung-Woo Cho, Meeyoung Park, Jinseu Park, Yong-Jun Cho, Soo Young Cho. Tat-NOL3 protects against hippocampal neuronal cell death induced by oxidative stress through the regulation of apoptotic pathways. International journal of molecular medicine. vol 38. issue 1. 2017-03-06. PMID:27221790. |
in addition, tat-nol3 protein transduced into the animal brains and significantly protected against neuronal cell death in the ca1 region of the hippocampus by regulating the activation of microglia and astrocytes. |
2017-03-06 |
2023-08-13 |
Not clear |
| Enas S Gad, Sawsan A Zaitone, Yasser M Moustaf. Pioglitazone and exenatide enhance cognition and downregulate hippocampal beta amyloid oligomer and microglia expression in insulin-resistant rats. Canadian journal of physiology and pharmacology. vol 94. issue 8. 2017-02-10. PMID:27389824. |
pioglitazone and exenatide enhance cognition and downregulate hippocampal beta amyloid oligomer and microglia expression in insulin-resistant rats. |
2017-02-10 |
2023-08-13 |
rat |
| Enas S Gad, Sawsan A Zaitone, Yasser M Moustaf. Pioglitazone and exenatide enhance cognition and downregulate hippocampal beta amyloid oligomer and microglia expression in insulin-resistant rats. Canadian journal of physiology and pharmacology. vol 94. issue 8. 2017-02-10. PMID:27389824. |
the current results confirmed that (1) feeding male rats with fructose syrup for 12 weeks resulted in a decline of learning and memory registered in eight-arm radial maze test; (2) treatment with pioglitazone or exenatide enhanced cognition, reduced hippocampal neurodegeneration, and reduced hippocampal microglia expression and beta amyloid oligomer deposition in a manner that is equal to monotherapies. |
2017-02-10 |
2023-08-13 |
rat |