| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Li Yang, Peiyu Jin, Xiaoyan Wang, Qing Zhou, Xiaoli Lin, Shuhua X. Fluoride activates microglia, secretes inflammatory factors and influences synaptic neuron plasticity in the hippocampus of rats. Neurotoxicology. vol 69. 2019-03-15. PMID:30273629. |
fluoride activates microglia, secretes inflammatory factors and influences synaptic neuron plasticity in the hippocampus of rats. |
2019-03-15 |
2023-08-13 |
rat |
| M Bolós, J R Perea, J Terreros-Roncal, N Pallas-Bazarra, J Jurado-Arjona, J Ávila, M Llorens-Martí. Absence of microglial CX3CR1 impairs the synaptic integration of adult-born hippocampal granule neurons. Brain, behavior, and immunity. vol 68. 2019-03-12. PMID:29017970. |
these data shed light on novel aspects of the regulation of adult hippocampal neurogenesis by microglia that could be highly relevant for research into mood disorders. |
2019-03-12 |
2023-08-13 |
mouse |
| Yu-Lin Ma, Ji-Lin Xia, Xi Ga. Suppressing Irf2bp2 expressions accelerates metabolic syndrome-associated brain injury and hepatic dyslipidemia. Biochemical and biophysical research communications. vol 503. issue 3. 2019-03-12. PMID:30131248. |
further, irf2bp2-deficiency accelerated the activation of astrocytes and microglia cells, as evidenced by the promoted expressions of glial fibrillary acidic protein (gfap) and iba-1 in hippocampus and hypothalamus of hfd-fed mice. |
2019-03-12 |
2023-08-13 |
mouse |
| Amy E Perkins, Michelle K Piazza, Terrence Dea. Stereological Analysis of Microglia in Aged Male and Female Fischer 344 Rats in Socially Relevant Brain Regions. Neuroscience. vol 377. 2019-03-11. PMID:29496632. |
since immune activation and subsequent increased expression of cytokines can suppress social behavior in young rodents, we examined age and sex differences in microglia within brain regions critical to social behavior regulation (pvn, bnst, and mea) as well as in the hippocampus. |
2019-03-11 |
2023-08-13 |
rat |
| Eva-Lotta von Rüden, Fabio Wolf, Michael Keck, Fabio Gualtieri, Marta Nowakowska, Michael Oglesbee, Heidrun Potschk. Genetic Modulation of HSPA1A Accelerates Kindling Progression and Exerts Pro-convulsant Effects. Neuroscience. vol 386. 2019-03-11. PMID:29964156. |
surprisingly, hspa1a overexpression did not affect microglia activation in the hippocampus. |
2019-03-11 |
2023-08-13 |
mouse |
| Gloria J DeWalt, Biraaj Mahajan, Andrea R Foster, Lauren D E Thompson, Andrew A Marttini, Eric V Schmidt, Sara Mansuri, Dwayne D'Souza, Shama B Patel, Madeline Tenenbaum, Karla I Brandao-Viruet, Dominique Thompson, Bryan Duong, Danica H Smith, Todd A Blute, William D Eldre. Region-specific alterations in astrocyte and microglia morphology following exposure to blasts in the mouse hippocampus. Neuroscience letters. vol 664. 2019-03-07. PMID:29133177. |
region-specific alterations in astrocyte and microglia morphology following exposure to blasts in the mouse hippocampus. |
2019-03-07 |
2023-08-13 |
mouse |
| Gloria J DeWalt, Biraaj Mahajan, Andrea R Foster, Lauren D E Thompson, Andrew A Marttini, Eric V Schmidt, Sara Mansuri, Dwayne D'Souza, Shama B Patel, Madeline Tenenbaum, Karla I Brandao-Viruet, Dominique Thompson, Bryan Duong, Danica H Smith, Todd A Blute, William D Eldre. Region-specific alterations in astrocyte and microglia morphology following exposure to blasts in the mouse hippocampus. Neuroscience letters. vol 664. 2019-03-07. PMID:29133177. |
the main objective of this study was to immunocytochemically examine morphological alterations in astrocytes and microglia in the hippocampus 48h following a single blast versus multiple blasts in adult c57bl/6 mice. |
2019-03-07 |
2023-08-13 |
mouse |
| Jong Whi Kim, Sung Min Nam, Dae Young Yoo, Hyo Young Jung, In Koo Hwang, Je Kyung Seong, Yeo Sung Yoo. Strain-specific differential expression of astrocytes and microglia in the mouse hippocampus. Brain and behavior. vol 8. issue 5. 2019-03-05. PMID:29761014. |
strain-specific differential expression of astrocytes and microglia in the mouse hippocampus. |
2019-03-05 |
2023-08-13 |
mouse |
| Masahiro Okamoto, Jason D Gray, Chloe S Larson, Syed Faraz Kazim, Hideaki Soya, Bruce S McEwen, Ana C Pereir. Riluzole reduces amyloid beta pathology, improves memory, and restores gene expression changes in a transgenic mouse model of early-onset Alzheimer's disease. Translational psychiatry. vol 8. issue 1. 2019-03-04. PMID:30108205. |
rna-sequencing showed that riluzole reversed many gene expression changes observed in the hippocampus of 5xfad mice, predominantly in expression of canonical gene markers for microglia, specifically disease-associated microglia (dam), as well as neurons and astrocytes. |
2019-03-04 |
2023-08-13 |
mouse |
| Etay Aloni, Antonella Ruggiero, Atan Gross, Menahem Sega. Learning Deficits in Adult Mitochondria Carrier Homolog 2 Forebrain Knockout Mouse. Neuroscience. vol 394. 2019-03-01. PMID:30401654. |
moreover, mtch2 bko express an increase in activated microglia, in addition to a reduction in neuron density in the hippocampus, but do not express amyloid-β plaques or neurofibrillary tangles. |
2019-03-01 |
2023-08-13 |
mouse |
| Gonzalo León-Espinosa, Mamen Regalado-Reyes, Javier DeFelipe, Alberto Muño. Changes in neocortical and hippocampal microglial cells during hibernation. Brain structure & function. vol 223. issue 4. 2019-02-26. PMID:29260372. |
using immunofluorescence, confocal microscopy, quantitative analysis methods and intracellular injections, we have characterized microglia morphological changes that occur in the neocortex and hippocampus of the syrian hamster during hibernation. |
2019-02-26 |
2023-08-13 |
Not clear |
| Salvador Dominguez, Mayra Gisel Flores-Montoya, Christina Sobi. Early chronic exposure to low-level lead alters total hippocampal microglia in pre-adolescent mice. Toxicology letters. vol 302. 2019-02-26. PMID:30352268. |
early chronic exposure to low-level lead alters total hippocampal microglia in pre-adolescent mice. |
2019-02-26 |
2023-08-13 |
mouse |
| Salvador Dominguez, Mayra Gisel Flores-Montoya, Christina Sobi. Early chronic exposure to low-level lead alters total hippocampal microglia in pre-adolescent mice. Toxicology letters. vol 302. 2019-02-26. PMID:30352268. |
a previous study showed that early lead exposure reduced microglia number in the dentate gyrus region of the hippocampus. |
2019-02-26 |
2023-08-13 |
mouse |
| Salvador Dominguez, Mayra Gisel Flores-Montoya, Christina Sobi. Early chronic exposure to low-level lead alters total hippocampal microglia in pre-adolescent mice. Toxicology letters. vol 302. 2019-02-26. PMID:30352268. |
given the critical role of microglia in brain development, it is important to determine whether these differences are unique to the dentate gyrus, or occur throughout the hippocampus. |
2019-02-26 |
2023-08-13 |
mouse |
| Salvador Dominguez, Mayra Gisel Flores-Montoya, Christina Sobi. Early chronic exposure to low-level lead alters total hippocampal microglia in pre-adolescent mice. Toxicology letters. vol 302. 2019-02-26. PMID:30352268. |
unbiased stereology was used to quantify microglia mean cell body number in total hippocampus, and compare the proportion of microglia in the ventral vs. dorsal regions. |
2019-02-26 |
2023-08-13 |
mouse |
| Salvador Dominguez, Mayra Gisel Flores-Montoya, Christina Sobi. Early chronic exposure to low-level lead alters total hippocampal microglia in pre-adolescent mice. Toxicology letters. vol 302. 2019-02-26. PMID:30352268. |
in lead exposed animals, microglia mean cell body number was reduced in total hippocampus; total hippocampal volume was reduced. |
2019-02-26 |
2023-08-13 |
mouse |
| Salvador Dominguez, Mayra Gisel Flores-Montoya, Christina Sobi. Early chronic exposure to low-level lead alters total hippocampal microglia in pre-adolescent mice. Toxicology letters. vol 302. 2019-02-26. PMID:30352268. |
contrary to study hypotheses, the distribution of hippocampal microglia in the ventral vs. dorsal hippocampal regions did not differ. |
2019-02-26 |
2023-08-13 |
mouse |
| Kohei Takahashi, Osamu Nakagawasai, Wataru Nemoto, Shogo Kadota, Jinichi Isono, Takayo Odaira, Wakana Sakuma, Yuichiro Arai, Takeshi Tadano, Koichi Tan-N. Memantine ameliorates depressive-like behaviors by regulating hippocampal cell proliferation and neuroprotection in olfactory bulbectomized mice. Neuropharmacology. vol 137. 2019-02-20. PMID:29729893. |
subsequently, we investigated the effects of mem on the distribution of tyrosine hydroxylase (th), altered microglia morphometry, and astrocyte and cell proliferation in the hippocampus with immunohistochemistry. |
2019-02-20 |
2023-08-13 |
mouse |
| Kohei Takahashi, Osamu Nakagawasai, Wataru Nemoto, Shogo Kadota, Jinichi Isono, Takayo Odaira, Wakana Sakuma, Yuichiro Arai, Takeshi Tadano, Koichi Tan-N. Memantine ameliorates depressive-like behaviors by regulating hippocampal cell proliferation and neuroprotection in olfactory bulbectomized mice. Neuropharmacology. vol 137. 2019-02-20. PMID:29729893. |
in contrast, the number of activated microglia and astrocytes and the levels of iba1, gfap, p-iκb-α, p-nf-κb p65, tnf-α, il-6, bax, and cleaved caspase-3 were increased in the hippocampus. |
2019-02-20 |
2023-08-13 |
mouse |
| Rui-Fang Wang, Guo-Fang Xue, Christian Hölscher, Miao-Jing Tian, Peng Feng, Ji-Ying Zheng, Dong-Fang L. Post-treatment with the GLP-1 analogue liraglutide alleviate chronic inflammation and mitochondrial stress induced by Status epilepticus. Epilepsy research. vol 142. 2019-02-19. PMID:29549796. |
once-daily after the induction of se for 7 days reduced chronic inflammation as shown by reduced numbers of activated microglia and astrocytes, and reduced levels of tnf-α and il-1ß in the hippocampus. |
2019-02-19 |
2023-08-13 |
Not clear |