| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shirin Hosseini, Esther Wilk, Kristin Michaelsen-Preusse, Ingo Gerhauser, Wolfgang Baumgärtner, Robert Geffers, Klaus Schughart, Martin Kort. Long-Term Neuroinflammation Induced by Influenza A Virus Infection and the Impact on Hippocampal Neuron Morphology and Function. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 38. issue 12. 2019-07-05. PMID:29487124. |
spine loss was associated with an increase in the number of activated microglia, reduced long-term potentiation in the hippocampus, and impairment in spatial memory formation, indicating that iav-associated inflammation induced functional and structural alterations in hippocampal networks. |
2019-07-05 |
2023-08-13 |
mouse |
| Xiaomei Feng, Martin Valdearcos, Yosuke Uchida, David Lutrin, Mervyn Maze, Suneil K Koliwa. Microglia mediate postoperative hippocampal inflammation and cognitive decline in mice. JCI insight. vol 2. issue 7. 2019-07-03. PMID:28405620. |
microglia mediate postoperative hippocampal inflammation and cognitive decline in mice. |
2019-07-03 |
2023-08-13 |
mouse |
| Xiaomei Feng, Martin Valdearcos, Yosuke Uchida, David Lutrin, Mervyn Maze, Suneil K Koliwa. Microglia mediate postoperative hippocampal inflammation and cognitive decline in mice. JCI insight. vol 2. issue 7. 2019-07-03. PMID:28405620. |
in rodents, postoperative cognitive decline (pocd) is associated with the inflammatory activation of hippocampal microglia. |
2019-07-03 |
2023-08-13 |
mouse |
| Fanny Gaudel, Delphine Stephan, Véréna Landel, Gilles Sicard, François Féron, Gaëlle Guiraudie-Capra. Expression of the Cerebral Olfactory Receptors Olfr110/111 and Olfr544 Is Altered During Aging and in Alzheimer's Disease-Like Mice. Molecular neurobiology. vol 56. issue 3. 2019-07-01. PMID:29984401. |
we observed that olfr110/111 and olfr544 proteins are mainly expressed by neurons in cortical and hippocampal regions and, to a lesser extent, by astrocytes, microglia, oligodendrocytes, and endothelial cells. |
2019-07-01 |
2023-08-13 |
mouse |
| Yu Zhao, Jinquan Cai, Zichen Liu, Yansheng Li, Chunxiong Zheng, Yadan Zheng, Qun Chen, Hongyun Chen, Feihe Ma, Yingli An, Lehui Xiao, Chuanlu Jiang, Linqi Shi, Chunsheng Kang, Yang Li. Nanocomposites Inhibit the Formation, Mitigate the Neurotoxicity, and Facilitate the Removal of β-Amyloid Aggregates in Alzheimer's Disease Mice. Nano letters. vol 19. issue 2. 2019-06-24. PMID:30444372. |
with the reduction of the pathological aβ oligomers, the nanocomposites attenuated the aβ-induced neuron damages, regained endocranial microglia's capability to phagocytose aβ, and eventually protected hippocampal neurons against apoptosis. |
2019-06-24 |
2023-08-13 |
mouse |
| Satoshi Okuyama, Mako Katoh, Tomoko Kanzaki, Yoshimi Kotani, Yoshiaki Amakura, Morio Yoshimura, Naohiro Fukuda, Takahisa Tamai, Atsushi Sawamoto, Mitsunari Nakajima, Yoshiko Furukaw. Auraptene/Naringin-Rich Fruit Juice of Citrus kawachiensis (Kawachi Bankan) Prevents Ischemia-Induced Neuronal Cell Death in Mouse Brain through Anti-Inflammatory Responses. Journal of nutritional science and vitaminology. vol 65. issue 1. 2019-06-24. PMID:30814414. |
the present study revealed that orally administration of the dried powder of this aur/ngin-rich fruit juice (2.5 g/kg/d) for 7 d to ischemic mice significantly suppressed the ischemia-induced neuronal cell death in the hippocampus, which was coincidently with the reduction of hyperactivation of microglia and astrocytes. |
2019-06-24 |
2023-08-13 |
mouse |
| Brittany F Osborne, Alexandra Turano, Jasmine I Caulfield, Jaclyn M Schwar. Sex- and region-specific differences in microglia phenotype and characterization of the peripheral immune response following early-life infection in neonatal male and female rats. Neuroscience letters. vol 692. 2019-06-21. PMID:30367955. |
instead, neonatal infection with e.coli increased the expression of a number of cytokines in the brain of both males and females similarly including tnf-α, il-1β, and cd11b (a marker of microglia activation) in the hippocampus and, in the spleen, tnf-α and il-1β. |
2019-06-21 |
2023-08-13 |
rat |
| Tirzah Kreisel, Brachi Wolf, Eli Keshet, Tamar Lich. Unique role for dentate gyrus microglia in neuroblast survival and in VEGF-induced activation. Glia. vol 67. issue 4. 2019-06-11. PMID:30453385. |
neurogenic roles of microglia (mg) are thought to include an active role in adult hippocampal neurogenesis in addition to their established roles in pruning surplus dendrites and clearing dead neuroblasts. |
2019-06-11 |
2023-08-13 |
Not clear |
| Ji Hyeon Ahn, Minah Song, Hyunjung Kim, Tae-Kyeong Lee, Cheol Woo Park, Young Eun Park, Jae-Chul Lee, Jun Hwi Cho, Young-Myeong Kim, In Koo Hwang, Moo-Ho Won, Joon Ha Par. Differential regional infarction, neuronal loss and gliosis in the gerbil cerebral hemisphere following 30 min of unilateral common carotid artery occlusion. Metabolic brain disease. vol 34. issue 1. 2019-06-06. PMID:30443768. |
in brief, our results demonstrate that 30 min of uocca in gerbils produced infarcts or selective neuronal death depending on ischemic severity in the ipsilateral cerebral cortex, striatum, thalamus and hippocampus, showing that astrocytes and microglia were differently reacted 5 days after uocca. |
2019-06-06 |
2023-08-13 |
Not clear |
| Wenqi Gao, Wei Wang, Gang Liu, Jing Zhang, Jian Yang, Zhifang Den. Allicin attenuated chronic social defeat stress induced depressive-like behaviors through suppression of NLRP3 inflammasome. Metabolic brain disease. vol 34. issue 1. 2019-06-06. PMID:30515710. |
microglia activation, as well as inflammatory cytokines elevation in the hippocampus of csds also down-regulated by administration of allicin. |
2019-06-06 |
2023-08-13 |
mouse |
| Cun-Quan Xiong, Hong-Cheng Zhou, Jian Wu, Nai-Zhou Gu. The Protective Effects and the Involved Mechanisms of Tanshinone IIA on Sepsis-Induced Brain Damage in Mice. Inflammation. vol 42. issue 1. 2019-06-03. PMID:30255286. |
tanshinone iia has a protective effect on the nerve of septic mice, and its mechanism may be related to the anti-inflammatory effects of the peripheral and hippocampal parts as well as inhibiting the over-activation of astrocytes and microglia. |
2019-06-03 |
2023-08-13 |
mouse |
| Shigeyoshi Saito, Kazuhiko Sawada, Ichio Aok. Prenatal Irradiation-Induced Hippocampal Abnormalities in Rats Evaluated Using Manganese-Enhanced MRI. Frontiers in neural circuits. vol 12. 2019-06-03. PMID:30618648. |
furthermore, glial components consisted largely by astrocytes and minor by microglia were densely distributed in the dg rather than in other hippocampal regions, and their density radiation-exposed rats. |
2019-06-03 |
2023-08-13 |
rat |
| Ahsia M Clayton, Qingmei Shao, Nina D Paauw, Ashtin B Giambrone, Joey P Granger, Junie P Warringto. Postpartum increases in cerebral edema and inflammation in response to placental ischemia during pregnancy. Brain, behavior, and immunity. vol 70. 2019-05-21. PMID:29588233. |
western blot analysis showed no changes in astrocyte marker, glial fibrillary acidic protein (gfap); however, the microglia marker, ionized calcium binding adaptor molecule (iba1) tended to increase in hippocampus of rupp-exposed rats. |
2019-05-21 |
2023-08-13 |
rat |
| Maria Elvira Brocca, Luciana Pietranera, Edo Ronald de Kloet, Alejandro Federico De Nicol. Mineralocorticoid Receptors, Neuroinflammation and Hypertensive Encephalopathy. Cellular and molecular neurobiology. vol 39. issue 4. 2019-05-17. PMID:30117098. |
then oxidative stress caused by vasculopathy and hypoxia further increases mr activation in hippocampal neurons and glia cells, activates microglia activation and pro-inflammatory mediators, and down-regulates anti-inflammatory factors. |
2019-05-17 |
2023-08-13 |
human |
| Bin Zheng, Shuncai Zhang, Yanlu Ying, Xinying Guo, Hengchang Li, Lixin Xu, Xiangcai Rua. Administration of Dexmedetomidine inhibited NLRP3 inflammasome and microglial cell activities in hippocampus of traumatic brain injury rats. Bioscience reports. vol 38. issue 5. 2019-05-17. PMID:30232232. |
administration of dexmedetomidine inhibited nlrp3 inflammasome and microglial cell activities in hippocampus of traumatic brain injury rats. |
2019-05-17 |
2023-08-13 |
rat |
| Joana Mendes Duarte, Rita Gaspar, Liliana Caetano, Patrícia Patrício, Carina Soares-Cunha, António Mateus-Pinheiro, Nuno Dinis Alves, Ana Rita Santos, Samira G Ferreira, Vanessa Sardinha, João Filipe Oliveira, Carlos Fontes-Ribeiro, Nuno Sousa, Rodrigo A Cunha, António F Ambrósio, Luísa Pinto, Ana João Rodrigues, Catarina A Gome. Region-specific control of microglia by adenosine A Glia. vol 67. issue 1. 2019-05-15. PMID:30461068. |
gender differences in microglia morphology, the higher prevalence of anxiety in women and the negative impact of anxiety in cognition, led us to specifically evaluate cognitive behavior and associated circuits (namely mpfc-dorsal hippocampus, dhip), as well as microglia morphology in female rats prenatally exposed to dexamethasone (in utero dex, iudex). |
2019-05-15 |
2023-08-13 |
rat |
| Meng Zhang, Yating Zhai, Yaping Sun, Wenli Zhang, Qian Li, Darrell Brann, Ruimin Wan. Swimming improves cognitive reserve in ovariectomized rats and enhances neuroprotection after global cerebral ischemia. Brain research. vol 1692. 2019-05-08. PMID:29778778. |
our results revealed that (1) morris water maze and shuttle box test analysis revealed that swimming improved cognitive function in ovx-rats, (2) the levels of psd95 and synaptophysin, as well as the protein expression of p-erk, p-creb and bdnf were all increased in the hippocampus after swimming with or without gci, and (3) swimming also increased the number of surviving neurons and il4 protein expression, while decreasing the iba1 (a microglia marker) level in the hippocampus. |
2019-05-08 |
2023-08-13 |
rat |
| Huixin Xu, Molly M Rajsombath, Pia Weikop, Dennis J Selko. Enriched environment enhances β-adrenergic signaling to prevent microglia inflammation by amyloid-β. EMBO molecular medicine. vol 10. issue 9. 2019-05-03. PMID:30093491. |
mice lacking β1/β2-adrenergic receptors showed no protection of microglia by ee in sh mice, quantification of norepinephrine in hippocampus and interstitial fluid showed that oaβ disrupted norepinephrine homeostasis, and microglial-specific analysis of β2-adrenergic receptors indicated a decreased receptor level. |
2019-05-03 |
2023-08-13 |
mouse |
| Giuseppina Talarico, Alessandro Trebbastoni, Giuseppe Bruno, Carlo de Len. Modulation of the Cannabinoid System: A New Perspective for the Treatment of the Alzheimer's Disease. Current neuropharmacology. vol 17. issue 2. 2019-05-01. PMID:29962346. |
cb2 receptors have been shown to be upregulated in neuritic plaque-associated microglia in the hippocampus and entorhinal cortex of patients, which suggests that these receptors play a role in the inflammatory pathology of ad. |
2019-05-01 |
2023-08-13 |
Not clear |
| Joanne O Davidson, Vittoria Draghi, Sean Whitham, Simerdeep K Dhillon, Guido Wassink, Laura Bennet, Alistair J Gun. How long is sufficient for optimal neuroprotection with cerebral cooling after ischemia in fetal sheep? Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 38. issue 6. 2019-04-30. PMID:28504050. |
ischemia was associated with profound loss of electroencephalogram (eeg) power, neurons in the cortex and hippocampus, and oligodendrocytes and myelin basic protein expression in the white matter, with increased iba-1-positive microglia and proliferation. |
2019-04-30 |
2023-08-13 |
Not clear |