| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Inken Waltl, Christopher Käufer, Sonja Bröer, Chintan Chhatbar, Luca Ghita, Ingo Gerhauser, Muneeb Anjum, Ulrich Kalinke, Wolfgang Lösche. Macrophage depletion by liposome-encapsulated clodronate suppresses seizures but not hippocampal damage after acute viral encephalitis. Neurobiology of disease. vol 110. 2019-09-06. PMID:29208406. |
clodronate liposome treatment did not reduce the increased iba1 and mac3 labeling in the hippocampus of infected mice, indicating that activated microglia may contribute to hippocampal damage. |
2019-09-06 |
2023-08-13 |
mouse |
| Lucas Taoro-Gonzalez, Yaiza M Arenas, Andrea Cabrera-Pastor, Vicente Felip. Extracellular cGMP Reverses Altered Membrane Expression of AMPA Receptors in Hippocampus of Hyperammonemic Rats: Underlying Mechanisms. Molecular neurobiology. vol 56. issue 6. 2019-08-29. PMID:30328550. |
reduction in il-1β levels is due to the reduction of microglia activation in hippocampus of hyperammonemic rats. |
2019-08-29 |
2023-08-13 |
rat |
| Durairaj Ragu-Varman, Mayra Macedo-Mendoza, Francisco Emmanuel Labrada-Moncada, Pamela Reyes-Ortega, Teresa Morales, Ataúlfo Martínez-Torres, Daniel Reyes-Har. Anorexia increases microglial density and cytokine expression in the hippocampus of young female rats. Behavioural brain research. vol 363. 2019-08-26. PMID:30690107. |
by using this model, we previously showed increased reactive astrocyte density in the rat dorsal hippocampus, suggesting a pro-inflammatory environment where microglia may play an important role. |
2019-08-26 |
2023-08-13 |
rat |
| Cai Zhang, Allan V Kalueff, Cai Son. Minocycline ameliorates anxiety-related self-grooming behaviors and alters hippocampal neuroinflammation, GABA and serum cholesterol levels in female Sprague-Dawley rats subjected to chronic unpredictable mild stress. Behavioural brain research. vol 363. 2019-08-26. PMID:30703398. |
(2019) study, to examine whether cums affects grooming behavior, and whether minocycline, a microglia antagonist, can correct these behavioral deficits, accompanied by altering hippocampal neuroinflammation, gaba and serum cholesterol levels. |
2019-08-26 |
2023-08-13 |
rat |
| Li Luo, Yilin Liu, Xing Tu, Xuxin Ren, Wenyan Zhao, Jing Liu, Li Zhang, Weiqiang Chen, Pei Zhang, Weicai Wang, Lanhai Lü, Mengxia Wan. Decreased expression of ubiquilin‑1 following neonatal hypoxia‑ischemic brain injury in mice. Molecular medicine reports. vol 19. issue 6. 2019-08-26. PMID:31059032. |
immunofluorescence staining demonstrated that ubqln was extensively distributed in the cerebral cortex and hippocampus, and ubqln was expressed in neurons, astrocytes and microglia in the brains of the hi brain injury model mice. |
2019-08-26 |
2023-08-13 |
mouse |
| Yuan Chao Xue, Chelsea M Ruller, Gabriel Fung, Yasir Mohamud, Haoyu Deng, Huitao Liu, Jingchun Zhang, Ralph Feuer, Honglin Lu. Enteroviral Infection Leads to Transactive Response DNA-Binding Protein 43 Pathology in Vivo. The American journal of pathology. vol 188. issue 12. 2019-08-20. PMID:30273599. |
histologic and immunohistochemical analysis of brain tissues demonstrated sustained inflammation (microglia and astrogliosis) and lesions in multiple regions of the brain (hippocampus, cerebral cortex, striatum, olfactory bulb, and putamen) in parallel with virus detection as early as 2 days for up to 90 days after infection. |
2019-08-20 |
2023-08-13 |
mouse |
| Yu Shi, Xiangyu Guo, Jie Zhang, Hanchi Zhou, Bei Sun, Jing Fen. DNA binding protein HMGB1 secreted by activated microglia promotes the apoptosis of hippocampal neurons in diabetes complicated with OSA. Brain, behavior, and immunity. vol 73. 2019-08-06. PMID:29920330. |
dna binding protein hmgb1 secreted by activated microglia promotes the apoptosis of hippocampal neurons in diabetes complicated with osa. |
2019-08-06 |
2023-08-13 |
mouse |
| Yu Shi, Xiangyu Guo, Jie Zhang, Hanchi Zhou, Bei Sun, Jing Fen. DNA binding protein HMGB1 secreted by activated microglia promotes the apoptosis of hippocampal neurons in diabetes complicated with OSA. Brain, behavior, and immunity. vol 73. 2019-08-06. PMID:29920330. |
we aimed to determine the relationship between the activation of microglia and the apoptosis of hippocampal neurons, specifically in terms of high mobility group box-1 (hmgb1), after high glucose (hg) and intermittent hypoxia (ih) exposure. |
2019-08-06 |
2023-08-13 |
mouse |
| Zhuangzhuang Chen, Di Zhong, Guozhong L. The role of microglia in viral encephalitis: a review. Journal of neuroinflammation. vol 16. issue 1. 2019-08-05. PMID:30967139. |
on the other hand, microglia mediate presynaptic membrane damage in the hippocampus through complement, resulting in long-term memory impairment and cognitive dysfunction in patients with encephalitis. |
2019-08-05 |
2023-08-13 |
Not clear |
| Xiao-Hua Sun, Ming-Fen Song, Hai-Dong Song, Yu-Wen Wang, Ming-Jin Luo, Li-Ming Yi. miR‑155 mediates inflammatory injury of hippocampal neuronal cells via the activation of microglia. Molecular medicine reports. vol 19. issue 4. 2019-08-01. PMID:30720115. |
mir‑155 mediates inflammatory injury of hippocampal neuronal cells via the activation of microglia. |
2019-08-01 |
2023-08-13 |
Not clear |
| Xiao-Hua Sun, Ming-Fen Song, Hai-Dong Song, Yu-Wen Wang, Ming-Jin Luo, Li-Ming Yi. miR‑155 mediates inflammatory injury of hippocampal neuronal cells via the activation of microglia. Molecular medicine reports. vol 19. issue 4. 2019-08-01. PMID:30720115. |
furthermore, conditioned medium from mir‑155‑treated microglia decreased the cell viability of ht22 hippocampal cells. |
2019-08-01 |
2023-08-13 |
Not clear |
| Xiao-Hua Sun, Ming-Fen Song, Hai-Dong Song, Yu-Wen Wang, Ming-Jin Luo, Li-Ming Yi. miR‑155 mediates inflammatory injury of hippocampal neuronal cells via the activation of microglia. Molecular medicine reports. vol 19. issue 4. 2019-08-01. PMID:30720115. |
mir‑155‑treated microglia increased the apoptosis of neuronal hippocampal cells by modulating the expression levels of apoptosis regulator bax, apoptosis regulator bcl‑2, pro‑caspase‑3 and cleaved‑caspase‑3. |
2019-08-01 |
2023-08-13 |
Not clear |
| Xiao-Hua Sun, Ming-Fen Song, Hai-Dong Song, Yu-Wen Wang, Ming-Jin Luo, Li-Ming Yi. miR‑155 mediates inflammatory injury of hippocampal neuronal cells via the activation of microglia. Molecular medicine reports. vol 19. issue 4. 2019-08-01. PMID:30720115. |
furthermore, the overexpression of suppressor of cytokine signaling 1 reversed the pro‑apoptotic effect of activated microglia on hippocampal neuronal cells. |
2019-08-01 |
2023-08-13 |
Not clear |
| Tianhai Wang, Hongge Zhu, Yanshen Hou, Weixin Gu, Haichuan Wu, Yiwen Luan, Cheng Xiao, Chunyi Zho. Galantamine reversed early postoperative cognitive deficit via alleviating inflammation and enhancing synaptic transmission in mouse hippocampus. European journal of pharmacology. vol 846. 2019-07-29. PMID:30586550. |
in comparison with sham mice (anesthesia only), the surgery mice exhibited cognitive deficits in a fear conditioning paradigm at postsurgery day 3-7, and increased numbers of microglia and elevated levels of pro-inflammatory cytokines (il-1β, il-6 and tnf-α) without change of anti-inflammatory cytokines (il-4 and il-10) in the hippocampus. |
2019-07-29 |
2023-08-13 |
mouse |
| Tianhai Wang, Hongge Zhu, Yanshen Hou, Weixin Gu, Haichuan Wu, Yiwen Luan, Cheng Xiao, Chunyi Zho. Galantamine reversed early postoperative cognitive deficit via alleviating inflammation and enhancing synaptic transmission in mouse hippocampus. European journal of pharmacology. vol 846. 2019-07-29. PMID:30586550. |
interestingly, daily intraperitoneal administration of galantamine, an inhibitor of acetylcholinesterase, reversed cognitive dysfunction in surgery mice and attenuated accumulation of microglia and protein levels of il-1β, il-6 and tnf-α in the hippocampus. |
2019-07-29 |
2023-08-13 |
mouse |
| Hanadie Yousef, Cathrin J Czupalla, Davis Lee, Michelle B Chen, Ashley N Burke, Kristy A Zera, Judith Zandstra, Elisabeth Berber, Benoit Lehallier, Vidhu Mathur, Ramesh V Nair, Liana N Bonanno, Andrew C Yang, Todd Peterson, Husein Hadeiba, Taylor Merkel, Jakob Körbelin, Markus Schwaninger, Marion S Buckwalter, Stephen R Quake, Eugene C Butcher, Tony Wyss-Cora. Aged blood impairs hippocampal neural precursor activity and activates microglia via brain endothelial cell VCAM1. Nature medicine. vol 25. issue 6. 2019-07-15. PMID:31086348. |
aged blood impairs hippocampal neural precursor activity and activates microglia via brain endothelial cell vcam1. |
2019-07-15 |
2023-08-13 |
mouse |
| Patricia Rivera, María Del Mar Fernández-Arjona, Daniel Silva-Peña, Eduardo Blanco, Antonio Vargas, María Dolores López-Ávalos, Jesús M Grondona, Antonia Serrano, Francisco Javier Pavón, Fernando Rodríguez de Fonseca, Juan Suáre. Pharmacological blockade of fatty acid amide hydrolase (FAAH) by URB597 improves memory and changes the phenotype of hippocampal microglia despite ethanol exposure. Biochemical pharmacology. vol 157. 2019-07-08. PMID:30098312. |
pharmacological blockade of fatty acid amide hydrolase (faah) by urb597 improves memory and changes the phenotype of hippocampal microglia despite ethanol exposure. |
2019-07-08 |
2023-08-13 |
rat |
| Patricia Rivera, María Del Mar Fernández-Arjona, Daniel Silva-Peña, Eduardo Blanco, Antonio Vargas, María Dolores López-Ávalos, Jesús M Grondona, Antonia Serrano, Francisco Javier Pavón, Fernando Rodríguez de Fonseca, Juan Suáre. Pharmacological blockade of fatty acid amide hydrolase (FAAH) by URB597 improves memory and changes the phenotype of hippocampal microglia despite ethanol exposure. Biochemical pharmacology. vol 157. 2019-07-08. PMID:30098312. |
urb597 increased microglial (iba-1+) cell population, and changed morphometric features (cell area and perimeter, roughness, fractal dimension, lacunarity) associated with activated microglia in the hippocampus of ethanol-exposed rats. |
2019-07-08 |
2023-08-13 |
rat |
| Rand S Eid, Jessica A Chaiton, Stephanie E Lieblich, Tamara S Bodnar, Joanne Weinberg, Liisa A M Gale. Early and late effects of maternal experience on hippocampal neurogenesis, microglia, and the circulating cytokine milieu. Neurobiology of aging. vol 78. 2019-07-08. PMID:30825663. |
early and late effects of maternal experience on hippocampal neurogenesis, microglia, and the circulating cytokine milieu. |
2019-07-08 |
2023-08-13 |
rat |
| Rand S Eid, Jessica A Chaiton, Stephanie E Lieblich, Tamara S Bodnar, Joanne Weinberg, Liisa A M Gale. Early and late effects of maternal experience on hippocampal neurogenesis, microglia, and the circulating cytokine milieu. Neurobiology of aging. vol 78. 2019-07-08. PMID:30825663. |
transient postpartum adaptations to the neuroimmune environment of the hippocampus were evidenced, as iba-1-immunoreactive microglia assumed a deramified morphology followed by increased density. |
2019-07-08 |
2023-08-13 |
rat |