| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bart Van Everbroeck, Itte Dobbeleir, Michèle De Waele, Evelyn De Leenheir, Ursula Lübke, Jean-Jacques Martin, Patrick Cra. Extracellular protein deposition correlates with glial activation and oxidative stress in Creutzfeldt-Jakob and Alzheimer's disease. Acta neuropathologica. vol 108. issue 3. 2004-11-16. PMID:15221335. |
three neocortical areas, the hippocampus, and the cerebellum of 20 cjd, 10 ad and 10 control patients were immunohistochemically examined for the presence of astroglia, microglia, and protein depositions. |
2004-11-16 |
2023-08-12 |
Not clear |
| Jae K Ryu, Sonia Franciosi, Prasongchai Sattayaprasert, Seung U Kim, James G McLarno. Minocycline inhibits neuronal death and glial activation induced by beta-amyloid peptide in rat hippocampus. Glia. vol 48. issue 1. 2004-10-27. PMID:15326618. |
hippocampal injection of a beta peptide also led to marked gliosis with numbers of microglia (increased by 26-fold) and immunoreactivity of astrocytes (increased by 11-fold) relative to control, as determined from immunohistochemical analysis. |
2004-10-27 |
2023-08-12 |
rat |
| Michiyo Tomita, Raza L Khan, Benjamin H Blehm, Thomas J Santor. The potential pathogenetic link between peripheral immune activation and the central innate immune response in neuropsychiatric systemic lupus erythematosus. Medical hypotheses. vol 62. issue 3. 2004-10-21. PMID:14975498. |
these observations suggest the hypothesis that central nervous system disease in sle is driven by cross-talk between the peripheral immune system and the brain's innate immune system, which results in the inexorable activation of astrocytes, microglia, and/or neurons within the hippocampus. |
2004-10-21 |
2023-08-12 |
mouse |
| Jari Huuskonen, Tiina Suuronen, Tapio Nuutinen, Sergiy Kyrylenko, Antero Salmine. Regulation of microglial inflammatory response by sodium butyrate and short-chain fatty acids. British journal of pharmacology. vol 141. issue 5. 2004-10-14. PMID:14744800. |
we observed that sodium butyrate is strongly anti-inflammatory against lps-induced responses in rat primary microglia as well as in hippocampal slice cultures and in neural cocultures of microglial cells, astrocytes and cerebellar granule neurons. |
2004-10-14 |
2023-08-12 |
rat |
| Olivera M Mitrasinovic, Christopher C Robinson, Daniel G Tenen, Yuen Ling Lee, Clara Poon, Greer M Murph. Biolistic expression of the macrophage colony stimulating factor receptor in organotypic cultures induces an inflammatory response. Journal of neuroscience research. vol 77. issue 3. 2004-09-09. PMID:15248298. |
to determine the effects of increased microglial expression of m-csfr in a complex organotypic environment, we developed a system for biolistic transfection of microglia in hippocampal slice cultures. |
2004-09-09 |
2023-08-12 |
mouse |
| Olivera M Mitrasinovic, Christopher C Robinson, Daniel G Tenen, Yuen Ling Lee, Clara Poon, Greer M Murph. Biolistic expression of the macrophage colony stimulating factor receptor in organotypic cultures induces an inflammatory response. Journal of neuroscience research. vol 77. issue 3. 2004-09-09. PMID:15248298. |
biolistic transfection of organotypic hippocampal cultures with the cd11b/c-fms construct resulted in expression of the c-fms mrna and protein that was localized to microglia. |
2004-09-09 |
2023-08-12 |
mouse |
| Olivera M Mitrasinovic, Christopher C Robinson, Daniel G Tenen, Yuen Ling Lee, Clara Poon, Greer M Murph. Biolistic expression of the macrophage colony stimulating factor receptor in organotypic cultures induces an inflammatory response. Journal of neuroscience research. vol 77. issue 3. 2004-09-09. PMID:15248298. |
furthermore, biolistic overexpression of m-csfr on microglia resulted in significantly increased production by the hippocampal cultures of the proinflammatory cytokines interleukin (il)-1alpha macrophage inflammatory protein (mip-1alpha), and trends toward increased production of il-6 and m-csf. |
2004-09-09 |
2023-08-12 |
mouse |
| Eszter Farkas, Adám Institóris, Ferenc Domoki, András Mihály, Paul G M Luiten, Ferenc Bar. Diazoxide and dimethyl sulphoxide prevent cerebral hypoperfusion-related learning dysfunction and brain damage after carotid artery occlusion. Brain research. vol 1008. issue 2. 2004-07-21. PMID:15145763. |
subsequently, the animals were sacrificed and neurons, astrocytes and microglia were labeled with immunocytochemistry in the dorsal hippocampus. |
2004-07-21 |
2023-08-12 |
rat |
| Mark A Petersen, Michael E Daile. Diverse microglial motility behaviors during clearance of dead cells in hippocampal slices. Glia. vol 46. issue 2. 2004-05-28. PMID:15042586. |
we used two-channel three-dimensional time-lapse fluorescence confocal imaging in live rat hippocampal slice cultures (1-7 days in vitro) to determine the motility behaviors of activated microglia as they engage dead and dying cells following traumatic brain tissue injury. |
2004-05-28 |
2023-08-12 |
rat |
| S Shoham, C Bejar, E Kovalev, M Weinstoc. Intracerebroventricular injection of streptozotocin causes neurotoxicity to myelin that contributes to spatial memory deficits in rats. Experimental neurology. vol 184. issue 2. 2004-04-02. PMID:14769399. |
stz caused selective injury to myelin and axons in the fornix and hippocampus in association with activation of microglia. |
2004-04-02 |
2023-08-12 |
rat |
| Ralph Andre, Rachel D Wheeler, Peter D Collins, Giamal N Luheshi, Stuart Pickering-Brown, Ian Kimber, Nancy J Rothwell, Emmanuel Pinteau. Identification of a truncated IL-18R beta mRNA: a putative regulator of IL-18 expressed in rat brain. Journal of neuroimmunology. vol 145. issue 1-2. 2004-03-22. PMID:14644029. |
both forms of il-18rbeta were expressed in rat cortex, striatum, hypothalamus, hippocampus, and also liver, and were detected in pure cultures of microglia, astrocytes and neurons. |
2004-03-22 |
2023-08-12 |
rat |
| Jeong Min Kim, Dongwook Son, Pyeongjae Lee, Kang Jin Lee, Hocheol Kim, Sun Yeou Ki. Ethyl acetate soluble fraction of Cnidium officinale MAKINO inhibits neuronal cell death by reduction of excessive nitric oxide production in lipopolysaccharide-treated rat hippocampal slice cultures and microglia cells. Journal of pharmacological sciences. vol 92. issue 1. 2004-03-11. PMID:12832858. |
ethyl acetate soluble fraction of cnidium officinale makino inhibits neuronal cell death by reduction of excessive nitric oxide production in lipopolysaccharide-treated rat hippocampal slice cultures and microglia cells. |
2004-03-11 |
2023-08-12 |
rat |
| Jaewon Lee, Wendy W Auyeung, Mark P Mattso. Interactive effects of excitotoxic injury and dietary restriction on microgliosis and neurogenesis in the hippocampus of adult mice. Neuromolecular medicine. vol 4. issue 3. 2004-03-09. PMID:14716025. |
because dietary restriction (dr) can increase hippocampal neurogenesis and promotes the survival of neurons following injury, we determined the effects of dr on the responses of neural stem cells, microglia, and astrocytes in the hippocampus to seizure-induced hippocampal damage. |
2004-03-09 |
2023-08-12 |
mouse |
| Massimo Rizzi, Carlo Perego, Marisa Aliprandi, Cristina Richichi, Teresa Ravizza, Daniele Colella, Jana Velískŏvá, Solomon L Moshé, M Grazia De Simoni, Annamaria Vezzan. Glia activation and cytokine increase in rat hippocampus by kainic acid-induced status epilepticus during postnatal development. Neurobiology of disease. vol 14. issue 3. 2004-03-05. PMID:14678765. |
thus, we investigated the activation of microglia and astrocytes, induction of cytokines, and hippocampal neuronal injury 4 and 24 h following kainic acid-induced se in postnatal day (pn) 9, 15, and 21 rats. |
2004-03-05 |
2023-08-12 |
rat |
| Michael G Drage, Gregory L Holmes, Thomas N Seyfrie. Hippocampal neurons and glia in epileptic EL mice. Journal of neurocytology. vol 31. issue 8-9. 2004-02-26. PMID:14501207. |
the results indicate that recurrent seizure activity in el mice is associated with abnormalities in hippocampal astrocytes and brain microglia, but is not associated with obvious neuronal loss or mossy fiber synaptic rearrangements. |
2004-02-26 |
2023-08-12 |
mouse |
| Christopher A McPherson, Julie Kubik, Robert N Wine, Christian Lefebvre D'Hellencourt, G Jean Harr. Alterations in cyclin A, B, and D1 in mouse dentate gyrus following TMT-induced hippocampal damage. Neurotoxicity research. vol 5. issue 5. 2004-01-28. PMID:14715453. |
to postnatal day 21 cd-1 male mice produced neuronal necrosis and loss of dentate granule cells, astrocyte hypertrophy, and microglia activation in the hippocampus within 24 hrs. |
2004-01-28 |
2023-08-12 |
mouse |
| Christopher A McPherson, Julie Kubik, Robert N Wine, Christian Lefebvre D'Hellencourt, G Jean Harr. Alterations in cyclin A, B, and D1 in mouse dentate gyrus following TMT-induced hippocampal damage. Neurotoxicity research. vol 5. issue 5. 2004-01-28. PMID:14715453. |
tnf-alpha mrna levels were significantly elevated in the hippocampus by 12 h and remained elevated for 72 h. mrna levels for cyclin a2 and cyclin b1 were elevated by approximately 2-fold at 72 h. immunohistochemistry suggested a cellular localization of cyclin a to microglia in the region of neuronal necrosis in the dentate, cyclin b in glial cells in juxtaposition to neurons in the hilus of the hippocampus and cyclin d1 to non-glial cells in the dentate. |
2004-01-28 |
2023-08-12 |
mouse |
| A Bordey, D D Spence. Chemokine modulation of high-conductance Ca(2+)-sensitive K(+) currents in microglia from human hippocampi. The European journal of neuroscience. vol 18. issue 10. 2004-01-26. PMID:14656339. |
thus, patch-clamp recordings of microglia were performed in hippocampal slices from seven patients who underwent surgery for pharmaco-resistant epilepsy. |
2004-01-26 |
2023-08-12 |
human |
| Kazuhiro Imamura, Nozomi Hishikawa, Makoto Sawada, Toshiharu Nagatsu, Mari Yoshida, Yoshio Hashizum. Distribution of major histocompatibility complex class II-positive microglia and cytokine profile of Parkinson's disease brains. Acta neuropathologica. vol 106. issue 6. 2004-01-16. PMID:14513261. |
the number of activated microglia not only in the sn and putamen but also in the hippocampus, transentorhinal cortex, cingulate cortex and temporal cortex in pd was significantly higher than that in the normal control. |
2004-01-16 |
2023-08-12 |
Not clear |
| Jee-Ching Hsu, Ying-Shiung Lee, Chen-Nen Chang, Huo-Li Chuang, Eng-Ang Ling, Chyn-Tair La. Sleep deprivation inhibits expression of NADPH-d and NOS while activating microglia and astroglia in the rat hippocampus. Cells, tissues, organs. vol 173. issue 4. 2004-01-08. PMID:12766354. |
sleep deprivation inhibits expression of nadph-d and nos while activating microglia and astroglia in the rat hippocampus. |
2004-01-08 |
2023-08-12 |
rat |