| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Terhi J Pirttilä, Katarzyna Lukasiuk, Katarina Håkansson, Anders Grubb, Magnus Abrahamson, Asla Pitkäne. Cystatin C modulates neurodegeneration and neurogenesis following status epilepticus in mouse. Neurobiology of disease. vol 20. issue 2. 2006-01-23. PMID:16242633. |
the present data showed that the expression of cystatin c protein increased in the mouse hippocampus 7 days following se and localized mainly to astrocytes and microglia. |
2006-01-23 |
2023-08-12 |
mouse |
| Yu-Peng Liu, Hsin-I Lin, Shun-Fen Tzen. Tumor necrosis factor-alpha and interleukin-18 modulate neuronal cell fate in embryonic neural progenitor culture. Brain research. vol 1054. issue 2. 2005-12-21. PMID:16054598. |
neurogenesis in the adult hippocampus has been found to be inhibited by a proinflammatory cytokine, interleukin-6 (il-6), suggesting that activated microglia in the inflamed brain may control neurogenesis. |
2005-12-21 |
2023-08-12 |
Not clear |
| Jing-Hui Dong, Guo-Xin Ying, Xin Liu, Wen-Yuan Wang, Yan Wang, Zi-Mei Ni, Chang-Fu Zho. Expression of thymosin beta4 mRNA by activated microglia in the denervated hippocampus. Neuroreport. vol 16. issue 15. 2005-12-01. PMID:16189468. |
expression of thymosin beta4 mrna by activated microglia in the denervated hippocampus. |
2005-12-01 |
2023-08-12 |
Not clear |
| S Rosi, C B Pert, M R Ruff, K McGann-Gramling, G L Wen. Chemokine receptor 5 antagonist D-Ala-peptide T-amide reduces microglia and astrocyte activation within the hippocampus in a neuroinflammatory rat model of Alzheimer's disease. Neuroscience. vol 134. issue 2. 2005-11-15. PMID:15979806. |
chemokine receptor 5 antagonist d-ala-peptide t-amide reduces microglia and astrocyte activation within the hippocampus in a neuroinflammatory rat model of alzheimer's disease. |
2005-11-15 |
2023-08-12 |
rat |
| S Rosi, C B Pert, M R Ruff, K McGann-Gramling, G L Wen. Chemokine receptor 5 antagonist D-Ala-peptide T-amide reduces microglia and astrocyte activation within the hippocampus in a neuroinflammatory rat model of Alzheimer's disease. Neuroscience. vol 134. issue 2. 2005-11-15. PMID:15979806. |
reactive microglia and astrocytes are observed within the hippocampus during the early stages of the disease. |
2005-11-15 |
2023-08-12 |
rat |
| Ching-Liang Hsieh, Chi-Long Chen, Nou-Ying Tang, Chin-Min Chuang, Ching-Tou Hsieh, Su-Yin Chiang, Jaung-Geng Lin, Sheng-Feng Hs. Gastrodia elata BL mediates the suppression of nNOS and microglia activation to protect against neuronal damage in kainic acid-treated rats. The American journal of Chinese medicine. vol 33. issue 4. 2005-11-07. PMID:16173534. |
the aim of the present study was to further investigate possible physiological mechanisms of ge against activities of neuronal nitric oxide synthase (nnos) and microglia in ka-treated rats; 0.5 g/kg and 1.0 g/kg of ge extract were administered orally, whereas 20 mg/kg of n-nitro-l-arginine methyl ester (l-name) was administered intraperitoneally (ip), both at 30 minutes prior to ka (2 microg/2 microl) being injected into the right hippocampus region of rats. |
2005-11-07 |
2023-08-12 |
rat |
| Kazuhiro Imamura, Nozomi Hishikawa, Kenji Ono, Hiromi Suzuki, Makoto Sawada, Toshiharu Nagatsu, Mari Yoshida, Yoshio Hashizum. Cytokine production of activated microglia and decrease in neurotrophic factors of neurons in the hippocampus of Lewy body disease brains. Acta neuropathologica. vol 109. issue 2. 2005-09-21. PMID:15619128. |
cytokine production of activated microglia and decrease in neurotrophic factors of neurons in the hippocampus of lewy body disease brains. |
2005-09-21 |
2023-08-12 |
Not clear |
| Kazuhiro Imamura, Nozomi Hishikawa, Kenji Ono, Hiromi Suzuki, Makoto Sawada, Toshiharu Nagatsu, Mari Yoshida, Yoshio Hashizum. Cytokine production of activated microglia and decrease in neurotrophic factors of neurons in the hippocampus of Lewy body disease brains. Acta neuropathologica. vol 109. issue 2. 2005-09-21. PMID:15619128. |
we have already reported numerous mhc class ii-positive microglia in the hippocampus in pd patients, and that this phenomenon may be responsible for functional changes in the neurons and the cognitive decline in pd patients. |
2005-09-21 |
2023-08-12 |
Not clear |
| Kazuhiro Imamura, Nozomi Hishikawa, Kenji Ono, Hiromi Suzuki, Makoto Sawada, Toshiharu Nagatsu, Mari Yoshida, Yoshio Hashizum. Cytokine production of activated microglia and decrease in neurotrophic factors of neurons in the hippocampus of Lewy body disease brains. Acta neuropathologica. vol 109. issue 2. 2005-09-21. PMID:15619128. |
in this study, we have investigated the distribution of activated microglia and the immunohistochemical and the mrna expression of several cytokines and neurotrophic factors of the hippocampus in pd and dementia with lewy bodies (dlb). |
2005-09-21 |
2023-08-12 |
Not clear |
| Kazuhiro Imamura, Nozomi Hishikawa, Kenji Ono, Hiromi Suzuki, Makoto Sawada, Toshiharu Nagatsu, Mari Yoshida, Yoshio Hashizum. Cytokine production of activated microglia and decrease in neurotrophic factors of neurons in the hippocampus of Lewy body disease brains. Acta neuropathologica. vol 109. issue 2. 2005-09-21. PMID:15619128. |
mhc class ii-positive microglia were distributed diffusely in the hippocampus of pd and dlb brains. |
2005-09-21 |
2023-08-12 |
Not clear |
| Kazuhiro Imamura, Nozomi Hishikawa, Kenji Ono, Hiromi Suzuki, Makoto Sawada, Toshiharu Nagatsu, Mari Yoshida, Yoshio Hashizum. Cytokine production of activated microglia and decrease in neurotrophic factors of neurons in the hippocampus of Lewy body disease brains. Acta neuropathologica. vol 109. issue 2. 2005-09-21. PMID:15619128. |
the increased number of activated microglia and the production of neurotrophic cytokines such as il-6, together with the decreased expression of the neurotrophic factors of neurons in the hippocampus of pd and dlb brains, may be related to functional cellular changes associated with dementia. |
2005-09-21 |
2023-08-12 |
Not clear |
| Michael T Heneka, Magdalena Sastre, Lucia Dumitrescu-Ozimek, Anne Hanke, Ilse Dewachter, Cuno Kuiperi, Kerry O'Banion, Thomas Klockgether, Fred Van Leuven, Gary E Landret. Acute treatment with the PPARgamma agonist pioglitazone and ibuprofen reduces glial inflammation and Abeta1-42 levels in APPV717I transgenic mice. Brain : a journal of neurology. vol 128. issue Pt 6. 2005-09-13. PMID:15817521. |
we report that an acute 7 day oral treatment of 10-month-old appv717i mice with the ppargamma agonist pioglitazone or the nsaid ibuprofen resulted in a reduction in the number of activated microglia and reactive astrocytes in the hippocampus and cortex. |
2005-09-13 |
2023-08-12 |
mouse |
| G J Guillemin, B J Brew, C E Noonan, O Takikawa, K M Culle. Indoleamine 2,3 dioxygenase and quinolinic acid immunoreactivity in Alzheimer's disease hippocampus. Neuropathology and applied neurobiology. vol 31. issue 4. 2005-09-06. PMID:16008823. |
in ad hippocampus, both ido- and quin-immunoreactivity (-ir) was detected in cortical microglia, astrocytes and neurones, with microglial and astrocytic expression of ido and quin highest in the perimeter of senile plaques. |
2005-09-06 |
2023-08-12 |
Not clear |
| Oleg Butovsky, Adolfo E Talpalar, Keren Ben-Yaakov, Michal Schwart. Activation of microglia by aggregated beta-amyloid or lipopolysaccharide impairs MHC-II expression and renders them cytotoxic whereas IFN-gamma and IL-4 render them protective. Molecular and cellular neurosciences. vol 29. issue 3. 2005-08-29. PMID:15890528. |
using an in vitro assay of hippocampal slices, we show that the cytokines interferon-gamma and (especially) interleukin-4, characteristic of pro-inflammatory and anti-inflammatory t cells, respectively, can make microglia neuroprotective. |
2005-08-29 |
2023-08-12 |
Not clear |
| Jeong-Sun Choi, Ha-Young Kim, Jin-Woong Chung, Myung-Hoon Chun, Seong Yun Kim, Shin-Hee Yoon, Mun-Yong Le. Activation of Src tyrosine kinase in microglia in the rat hippocampus following transient forebrain ischemia. Neuroscience letters. vol 380. issue 1-2. 2005-07-28. PMID:15854740. |
activation of src tyrosine kinase in microglia in the rat hippocampus following transient forebrain ischemia. |
2005-07-28 |
2023-08-12 |
rat |
| Jeong-Sun Choi, Ha-Young Kim, Jin-Woong Chung, Myung-Hoon Chun, Seong Yun Kim, Shin-Hee Yoon, Mun-Yong Le. Activation of Src tyrosine kinase in microglia in the rat hippocampus following transient forebrain ischemia. Neuroscience letters. vol 380. issue 1-2. 2005-07-28. PMID:15854740. |
these results demonstrate increased phosphorylation of src in activated microglia of the post-ischemic hippocampus, indicating that src signaling may be involved in the microglial reaction to an ischemic insult. |
2005-07-28 |
2023-08-12 |
rat |
| Margaret M Moga, Dominique Dempah, Dan Zho. Annexin 7-immunoreactive microglia in the hippocampus of control and adrenalectomized rats. Neuroscience letters. vol 380. issue 1-2. 2005-07-28. PMID:15854748. |
annexin 7-immunoreactive microglia in the hippocampus of control and adrenalectomized rats. |
2005-07-28 |
2023-08-12 |
rat |
| Margaret M Moga, Dominique Dempah, Dan Zho. Annexin 7-immunoreactive microglia in the hippocampus of control and adrenalectomized rats. Neuroscience letters. vol 380. issue 1-2. 2005-07-28. PMID:15854748. |
anx7 was co-localized with ox42 in microglia distributed throughout the hippocampus of both control and adx animals. |
2005-07-28 |
2023-08-12 |
rat |
| Margaret M Moga, Dominique Dempah, Dan Zho. Annexin 7-immunoreactive microglia in the hippocampus of control and adrenalectomized rats. Neuroscience letters. vol 380. issue 1-2. 2005-07-28. PMID:15854748. |
no reactive microglia were present in the hippocampus of sham-adx or adx + corticosterone treated animals. |
2005-07-28 |
2023-08-12 |
rat |
| Margaret M Moga, Dominique Dempah, Dan Zho. Annexin 7-immunoreactive microglia in the hippocampus of control and adrenalectomized rats. Neuroscience letters. vol 380. issue 1-2. 2005-07-28. PMID:15854748. |
our results show that anx7 is abundantly expressed in the rat hippocampus by different microglial forms (e.g., ramified, activated and reactive microglia), suggesting an important role for this calcium-binding protein in microglial ca2+-dependent processes. |
2005-07-28 |
2023-08-12 |
rat |