| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shozo Jinno, Toshio Kosak. Reduction of Iba1-expressing microglial process density in the hippocampus following electroconvulsive shock. Experimental neurology. vol 212. issue 2. 2008-09-02. PMID:18538764. |
the optical disector analysis demonstrated that ecs did not affect the numerical densities of iba1-positive microglia and s100beta-positive astrocytes in the hippocampus. |
2008-09-02 |
2023-08-12 |
mouse |
| Y Nasu-Nishimura, Y Taniuchi, T Nishimura, A Sakudo, K Nakajima, Y Ano, K Sugiura, S Sakaguchi, S Itohara, T Onoder. Cellular prion protein prevents brain damage after encephalomyocarditis virus infection in mice. Archives of virology. vol 153. issue 6. 2008-08-20. PMID:18408883. |
histopathological studies revealed that prnp(+/+) mice infected with 600 pfu of emcv-b showed more severe infiltration of inflammatory cells, accompanied by higher activation of microglia cells around the hippocampus, than prnp(-/-) mice; viz., no differences in the brain virus titer between these two lines of mice. |
2008-08-20 |
2023-08-12 |
mouse |
| Liliana Bernardino, Silvia Balosso, Teresa Ravizza, Nicola Marchi, George Ku, John C Randle, João O Malva, Annamaria Vezzan. Inflammatory events in hippocampal slice cultures prime neuronal susceptibility to excitotoxic injury: a crucial role of P2X7 receptor-mediated IL-1beta release. Journal of neurochemistry. vol 106. issue 1. 2008-08-19. PMID:18384650. |
we investigated the consequences of transient application of specific stimuli mimicking inflammation to hippocampal tissue on microglia activation and neuronal cell vulnerability to a subsequent excitotoxic insult. |
2008-08-19 |
2023-08-12 |
mouse |
| Karen Bulloch, Melinda M Miller, Judit Gal-Toth, Teresa A Milner, Andres Gottfried-Blackmore, Elizabeth M Waters, Ulrike W Kaunzner, Kang Liu, Randall Lindquist, Michel C Nussenzweig, Ralph M Steinman, Bruce S McEwe. CD11c/EYFP transgene illuminates a discrete network of dendritic cells within the embryonic, neonatal, adult, and injured mouse brain. The Journal of comparative neurology. vol 508. issue 5. 2008-08-01. PMID:18386786. |
kainic acid-induced seizures revealed that eyfp(+) bdc responded to damage of the hippocampus and displayed morphologies similar to those described for seizure-activated egfp(+) microglia in the hippocampus of cfms (csf-1r) egfp mice. |
2008-08-01 |
2023-08-12 |
mouse |
| Clotilde Lauro, Silvia Di Angelantonio, Raffaela Cipriani, Fabrizia Sobrero, Letizia Antonilli, Valentina Brusadin, Davide Ragozzino, Cristina Limatol. Activity of adenosine receptors type 1 Is required for CX3CL1-mediated neuroprotection and neuromodulation in hippocampal neurons. Journal of immunology (Baltimore, Md. : 1950). vol 180. issue 11. 2008-07-18. PMID:18490761. |
using cultured hippocampal neuronal cell preparations, obtained from cx(3)cr1(-/-) (cx(3)cr1(gfp/gfp)) mice, we report that these same effects are mimicked by exposing neurons to a medium conditioned with cx(3)cl1-treated mouse microglial cell line bv2 (bv2-st medium). |
2008-07-18 |
2023-08-12 |
mouse |
| Marcel Maier, Ying Peng, Liying Jiang, Timothy J Seabrook, Michael C Carroll, Cynthia A Lemer. Complement C3 deficiency leads to accelerated amyloid beta plaque deposition and neurodegeneration and modulation of the microglia/macrophage phenotype in amyloid precursor protein transgenic mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 25. 2008-07-10. PMID:18562603. |
in contrast, at 17 months of age, app;c3(-/-) mice showed significant changes of up to twofold increased total abeta and fibrillar amyloid plaque burden in midfrontal cortex and hippocampus, which correlated with (1) significantly increased tris-buffered saline (tbs)-insoluble abeta(42) levels and reduced tbs-soluble abeta(42) and abeta(40) levels in brain homogenates, (2) a trend for increased abeta levels in the plasma, (3) a significant loss of neuronal-specific nuclear protein-positive neurons in the hippocampus, and (4) differential activation of microglia toward a more alternative phenotype (e.g., significantly increased cd45-positive microglia, increased brain levels of interleukins 4 and 10, and reduced levels of cd68, f4/80, inducible nitric oxide synthase, and tumor necrosis factor). |
2008-07-10 |
2023-08-12 |
mouse |
| Ming-Ou Lu, Xing-Mei Zhang, Eilhard Mix, Hernan Concha Quezada, Tao Jin, Jie Zhu, Abdu Ade. TNF-alpha receptor 1 deficiency enhances kainic acid-induced hippocampal injury in mice. Journal of neuroscience research. vol 86. issue 7. 2008-07-08. PMID:18189316. |
in addition, obvious neurodegeneration, enhanced microglia activation, and astrogliosis in the hippocampus, as well as increased locomotor activity, were found in tnfr1-/- mice compared with the wild-type controls 8 days after ka delivery. |
2008-07-08 |
2023-08-12 |
mouse |
| Fuxing Zhang, Kujumon I Vadakkan, Susan S Kim, Long-Jun Wu, Yuze Shang, Min Zhu. Selective activation of microglia in spinal cord but not higher cortical regions following nerve injury in adult mouse. Molecular pain. vol 4. 2008-07-08. PMID:18423014. |
in contrast, microglia was not activated in supraspinal regions of the cns, including the anterior cingulate cortex (acc), prefrontal cortex (pfc), primary and secondary somatosensory cortex (s1 and s2), insular cortex (ic), amygdala, hippocampus, periaqueductal gray (pag) and rostral ventromedial medulla (rvm). |
2008-07-08 |
2023-08-12 |
mouse |
| Radoslaw Rola, Kelly Fishman, Jennifer Baure, Susanna Rosi, Kathleen R Lamborn, Andre Obenaus, Gregory A Nelson, John R Fik. Hippocampal neurogenesis and neuroinflammation after cranial irradiation with (56)Fe particles. Radiation research. vol 169. issue 6. 2008-07-03. PMID:18494546. |
results showed that there were few changes after 0.5 gy, but that there was a dose-related decrease in hippocampal neurogenesis and a dose-related increase in numbers of newly born activated microglia from 0.5-4.0 gy. |
2008-07-03 |
2023-08-12 |
mouse |
| S Xapelli, L Bernardino, R Ferreira, S Grade, A P Silva, J R Salgado, C Cavadas, E Grouzmann, F R Poulsen, B Jakobsen, C R Oliveira, J Zimmer, J O Malv. Interaction between neuropeptide Y (NPY) and brain-derived neurotrophic factor in NPY-mediated neuroprotection against excitotoxicity: a role for microglia. The European journal of neuroscience. vol 27. issue 8. 2008-07-01. PMID:18412629. |
thus, an increase of ampa-receptor mediated neurodegeneration, in the mouse hippocampus, was prevented by neuroprotective pathways activated by npy receptors (y(1) and y(2)), which can be affected by bdnf released by microglia and neurons. |
2008-07-01 |
2023-08-12 |
mouse |
| Long-Jun Wu, Min Zhu. Resting microglial motility is independent of synaptic plasticity in mammalian brain. Journal of neurophysiology. vol 99. issue 4. 2008-06-17. PMID:18256162. |
here we performed a combination of simultaneous electrophysiology and time-lapse confocal imaging in green fluorescent protein-labeled microglia in acute hippocampal slices. |
2008-06-17 |
2023-08-12 |
Not clear |
| Xuesong Chen, Jeremy W Gawryluk, John F Wagener, Othman Ghribi, Jonathan D Geige. Caffeine blocks disruption of blood brain barrier in a rabbit model of Alzheimer's disease. Journal of neuroinflammation. vol 5. 2008-06-12. PMID:18387175. |
olfactory bulbs (and for some studies hippocampus and cerebral cortex as well) were evaluated for bbb leakage, bbb tight junction protein expression levels, activation of astrocytes, and microglia density using histological, immunostaining and immunoblotting techniques. |
2008-06-12 |
2023-08-12 |
rabbit |
| Mariela Susana Borán, María Antonia Baltrons, Agustina Garcí. The ANP-cGMP-protein kinase G pathway induces a phagocytic phenotype but decreases inflammatory gene expression in microglial cells. Glia. vol 56. issue 4. 2008-05-30. PMID:18186083. |
the morphological changes and the decrease of lps-induced nos-2 expression produced by anp in cultured microglia are also observed by immunostaining in organotypic cultures from rat hippocampus. |
2008-05-30 |
2023-08-12 |
rat |
| G Jean Harry, Jason A Funk, Christian Lefebvre d'Hellencourt, Christopher A McPherson, Mineyoshi Aoyam. The type 1 interleukin 1 receptor is not required for the death of murine hippocampal dentate granule cells and microglia activation. Brain research. vol 1194. 2008-05-30. PMID:18191113. |
the type 1 interleukin 1 receptor is not required for the death of murine hippocampal dentate granule cells and microglia activation. |
2008-05-30 |
2023-08-12 |
mouse |
| David Muyllaert, Dick Terwel, Anna Kremer, Kristina Sennvik, Peter Borghgraef, Herman Devijver, Ilse Dewachter, Fred Van Leuve. Neurodegeneration and neuroinflammation in cdk5/p25-inducible mice: a model for hippocampal sclerosis and neocortical degeneration. The American journal of pathology. vol 172. issue 2. 2008-04-08. PMID:18202185. |
the inducible p25 mice present as a model for neurodegeneration in hippocampal sclerosis and neocortical degeneration, with important contributions of activated microglia. |
2008-04-08 |
2023-08-12 |
mouse |
| Noriyuki Akahoshi, Yoshiya L Murashima, Toshiyuki Himi, Yasuki Ishizaki, Isao Ishi. Increased expression of the lysosomal protease cathepsin S in hippocampal microglia following kainate-induced seizures. Neuroscience letters. vol 429. issue 2-3. 2008-03-04. PMID:17997037. |
increased expression of the lysosomal protease cathepsin s in hippocampal microglia following kainate-induced seizures. |
2008-03-04 |
2023-08-12 |
mouse |
| Tom Schilling, Claudia Ede. Ion channel expression in resting and activated microglia of hippocampal slices from juvenile mice. Brain research. vol 1186. 2008-03-04. PMID:18005942. |
ion channel expression in resting and activated microglia of hippocampal slices from juvenile mice. |
2008-03-04 |
2023-08-12 |
mouse |
| Tom Schilling, Claudia Ede. Ion channel expression in resting and activated microglia of hippocampal slices from juvenile mice. Brain research. vol 1186. 2008-03-04. PMID:18005942. |
in summary, our data indicate that the physiological properties of microglia in acute and cultured hippocampal slices from juvenile mice differ markedly from those of microglia cultured in vitro and from those of microglia in adult brain slices. |
2008-03-04 |
2023-08-12 |
mouse |
| Adam Institoris, Eszter Farkas, Sandor Berczi, Zoltan Sule, Ferenc Bar. Effects of cyclooxygenase (COX) inhibition on memory impairment and hippocampal damage in the early period of cerebral hypoperfusion in rats. European journal of pharmacology. vol 574. issue 1. 2008-01-17. PMID:17719573. |
neurons in the hippocampus were subjected to immunocytochemical labeling with cresyl violet, the dendrites with microtubule-associated protein-2, astrocytes with glial fibrillary acidic protein and microglia activation with ox-42 antibody. |
2008-01-17 |
2023-08-12 |
rat |
| M S Petrik, J M B Wilson, S C Grant, S J Blackband, R C Tabata, X Shan, C Krieger, C A Sha. Magnetic resonance microscopy and immunohistochemistry of the CNS of the mutant SOD murine model of ALS reveals widespread neural deficits. Neuromolecular medicine. vol 9. issue 3. 2007-12-27. PMID:17914180. |
increased apoptosis, gfap positive astrocytes, and/or activated microglia were observed in all those cns regions that showed volume loss except for the hippocampus. |
2007-12-27 |
2023-08-12 |
mouse |