| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Teresa Ravizza, Massimo Rizzi, Carlo Perego, Cristina Richichi, Jana Velísková, Solomon L Moshé, M Grazia De Simoni, Annamaria Vezzan. Inflammatory response and glia activation in developing rat hippocampus after status epilepticus. Epilepsia. vol 46 Suppl 5. 2005-07-28. PMID:15987264. |
we investigated the activation of microglia and astrocytes, induction of cytokines, and hippocampal neuronal damage, 4 and 24 h after kainic acid-induced status epilepticus (se) in postnatal day (pn) 9, 15, and 21 rats. |
2005-07-28 |
2023-08-12 |
rat |
| Hong-Won Suh, Han-Kyu Lee, Young-Jun Seo, Min-Soo Kwon, Eon-Jeong Shim, Jin-Young Lee, Seong-Soo Choi, Jong-Ho Le. Kainic acid (KA)-induced Ca2+/calmodulin-dependent protein kinase II (CaMK II) expression in the neurons, astrocytes and microglia of the mouse hippocampal CA3 region, and the phosphorylated CaMK II only in the hippocampal neurons. Neuroscience letters. vol 381. issue 3. 2005-07-26. PMID:15896474. |
kainic acid (ka)-induced ca2+/calmodulin-dependent protein kinase ii (camk ii) expression in the neurons, astrocytes and microglia of the mouse hippocampal ca3 region, and the phosphorylated camk ii only in the hippocampal neurons. |
2005-07-26 |
2023-08-12 |
mouse |
| Thomas van Groen, Inga Kadis. Transgenic AD model mice, effects of potential anti-AD treatments on inflammation and pathology. Brain research. Brain research reviews. vol 48. issue 2. 2005-07-15. PMID:15850676. |
plaques are surrounded by activated astrocytes and microglia, to study the relation between amyloid neuropathology and inflammation, we examined the changes in amyloid pathology in the hippocampus following three different treatments aimed at reducing the amyloid burden. |
2005-07-15 |
2023-08-12 |
mouse |
| Thomas van Groen, Inga Kadis. Transgenic AD model mice, effects of potential anti-AD treatments on inflammation and pathology. Brain research. Brain research reviews. vol 48. issue 2. 2005-07-15. PMID:15850676. |
the fimbria-fornix transection resulted in a substantial depletion of cholinergic markers in the hippocampus, but the lesion did not result in an alteration in hippocampal a deposition and inflammation (i.e., numbers or staining density of astrocytes and microglia). |
2005-07-15 |
2023-08-12 |
mouse |
| Rodrigo Herrera-Molina, Rommy von Bernhard. Transforming growth factor-beta 1 produced by hippocampal cells modulates microglial reactivity in culture. Neurobiology of disease. vol 19. issue 1-2. 2005-07-12. PMID:15837578. |
to identify regulatory mechanisms that might modulate over-activation of microglia, we evaluated the inhibition of microglial activation by factors secreted by hippocampal cells. |
2005-07-12 |
2023-08-12 |
Not clear |
| Ray D Beck, Clive Wasserfall, Grace K Ha, Jesse D Cushman, Zhi Huang, Mark A Atkinson, John M Petitt. Changes in hippocampal IL-15, related cytokines, and neurogenesis in IL-2 deficient mice. Brain research. vol 1041. issue 2. 2005-06-30. PMID:15829231. |
these cytokine changes, however, did not correlate with levels in the peripheral circulation, and there were no t cells or an increase in mhcii-positive microglia in the hippocampus of il-2 ko mice. |
2005-06-30 |
2023-08-12 |
mouse |
| Tatyana Tchaikovskaya, Vadim Fraifeld, Tinatin Urphanishvili, John H Andorfer, Peter Davies, Irving Listowsk. Glutathione S-transferase hGSTM3 and ageing-associated neurodegeneration: relationship to Alzheimer's disease. Mechanisms of ageing and development. vol 126. issue 2. 2005-06-13. PMID:15621212. |
immunocytochemistry performed with hgstm3-specific antisera, showed prominent staining of neuritic plaques, neurofibrillary tangles and microglia in sections of hippocampus obtained from patients with alzheimer's disease. |
2005-06-13 |
2023-08-12 |
human |
| Takahiro Tsuchiya, Kae Chang Park, Shinichi Toyonaga, Shoko M Yamada, Hiromichi Nakabayashi, Eiichi Nakai, Naoki Ikawa, Masato Furuya, Akira Tominaga, Keiji Shimiz. Characterization of microglia induced from mouse embryonic stem cells and their migration into the brain parenchyma. Journal of neuroimmunology. vol 160. issue 1-2. 2005-04-28. PMID:15710475. |
gfp(+) cells were detected mainly in corpus callosum and hippocampus but were rarely seen in cerebral cortex, where iba1, another marker of microglia, is primarily expressed. |
2005-04-28 |
2023-08-12 |
mouse |
| Jae-Hyuk Yi, Alan S Hazel. N-acetylcysteine attenuates early induction of heme oxygenase-1 following traumatic brain injury. Brain research. vol 1033. issue 1. 2005-04-25. PMID:15680334. |
astrocytes exhibited positive immunoreactivity for ho-1 in the injured cerebral cortex, hippocampus, and thalamus, while some neurons and microglia were also immunoreactive in the injured cortex. |
2005-04-25 |
2023-08-12 |
Not clear |
| G J Harry, R Sills, M J Schlosser, W E Maie. Neurodegeneration and glia response in rat hippocampus following nitro-L-arginine methyl ester (L-NAME). Neurotoxicity research. vol 3. issue 3. 2005-04-12. PMID:15111256. |
the co-administration of a hippocampal neurotoxicant, trimethyltin (tmt), with the last dose of l-name (2x/day), produced an additive response pattern of neuronal degeneration including both ca1-2 and ca3-4 pyramidal neurons accompanied by tmt-induced astrocyte hypertrophy and prominent microglia reactivity. |
2005-04-12 |
2023-08-12 |
rat |
| Kohichi Kawahara, Masataka Mori, Hitoshi Nakayam. [NO-induced apoptosis and ER stress in microglia]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 124. issue 6. 2005-04-05. PMID:15572844. |
we found activated rat type-1 microglia induced expression of inos and exhibited neurotoxic to rat hippocampal neurons. |
2005-04-05 |
2023-08-12 |
mouse |
| Han-Kyu Lee, Seong-Soo Choi, Eun-Jung Han, Jin-Young Lee, Min-Soo Kwon, Eon-Jeong Shim, Young-Jun Seo, Hong-Won Su. Role of nicotinic acetylcholine receptors in the regulation of kainic acid-induced hippocampal cell death in mice. Brain research bulletin. vol 64. issue 4. 2005-03-14. PMID:15561465. |
reactive astrocytes, which was meant by gfap ir, and activated microglia, which was meant by ox-42 ir, may be a good indicator for measuring the cell death in hippocampal regions by ka-induced excitotoxicity. |
2005-03-14 |
2023-08-12 |
mouse |
| Matthew Whiteman, Nam Sang Cheung, Yi-Zhun Zhu, Siew Hwa Chu, Jia Ling Siau, Boon Seng Wong, Jeffrey S Armstrong, Philip K Moor. Hydrogen sulphide: a novel inhibitor of hypochlorous acid-mediated oxidative damage in the brain? Biochemical and biophysical research communications. vol 326. issue 4. 2005-02-18. PMID:15607739. |
levels of myeloperoxidase (mpo), an enzyme that catalyses the formation of the oxidant hypochlorous acid (hocl), are elevated in the prefrontal cortex, hippocampal microglia, and neurons of ad patients where mpo co-localised with beta-amyloid plaques. |
2005-02-18 |
2023-08-12 |
human |
| E E Olson, R J McKeo. Characterization of cellular and neurological damage following unilateral hypoxia/ischemia. Journal of the neurological sciences. vol 227. issue 1. 2005-02-14. PMID:15546586. |
increased microglia activation was evident in the h/i-treated cortex and hippocampus versus sham cortex and hippocampus, particularly within areas undergoing degeneration. |
2005-02-14 |
2023-08-12 |
mouse |
| Hila Avidan, Jonathan Kipnis, Oleg Butovsky, Rachel R Caspi, Michal Schwart. Vaccination with autoantigen protects against aggregated beta-amyloid and glutamate toxicity by controlling microglia: effect of CD4+CD25+ T cells. European journal of immunology. vol 34. issue 12. 2005-02-03. PMID:15549735. |
in mouse hippocampal slices, microglia encountering activated t cells overcame the cytotoxicity of aggregated beta-amyloid. |
2005-02-03 |
2023-08-12 |
mouse |
| In Koo Hwang, Ki-Yeon Yoo, Duk Soo Kim, Seon-Gil Do, Yang-Seok Oh, Tae-Cheon Kang, Byoung Hee Han, Jong Sung Kim, Moo Ho Wo. Expression and changes of galanin in neurons and microglia in the hippocampus after transient forebrain ischemia in gerbils. Brain research. vol 1023. issue 2. 2005-01-24. PMID:15374745. |
expression and changes of galanin in neurons and microglia in the hippocampus after transient forebrain ischemia in gerbils. |
2005-01-24 |
2023-08-12 |
Not clear |
| Xiaoning Bi, Michel Baudry, Jihua Liu, Yueqin Yao, Lawrence Fu, Fernando Brucher, Gary Lync. Inhibition of geranylgeranylation mediates the effects of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors on microglia. The Journal of biological chemistry. vol 279. issue 46. 2005-01-21. PMID:15364922. |
both mevastatin and simvastatin caused a concentration- and time-dependent activation of microglia in cultured rat hippocampal slices. |
2005-01-21 |
2023-08-12 |
rat |
| Rommy von Bernhardi, Jaime Eugení. Microglial reactivity to beta-amyloid is modulated by astrocytes and proinflammatory factors. Brain research. vol 1025. issue 1-2. 2005-01-06. PMID:15464759. |
this pro-apoptotic effect was not observed in hippocampal cultures exposed to conditioned media obtained from mixed glial (astrocytes and microglia) cultures that had been exposed to abeta. |
2005-01-06 |
2023-08-12 |
Not clear |
| D Ramonet, M J Rodríguez, M Pugliese, N Mah. Putative glucosensing property in rat and human activated microglia. Neurobiology of disease. vol 17. issue 1. 2004-12-21. PMID:15350960. |
this study analyses activated microglia in an in vivo rat neurodegenerative model based on acute hippocampal glutamate receptor overactivation and in postmortem samples from patients with alzheimer's disease. |
2004-12-21 |
2023-08-12 |
human |
| Jeffrey M Craft, D Martin Watterson, Sally A Frautschy, Linda J Van Eldi. Aminopyridazines inhibit beta-amyloid-induced glial activation and neuronal damage in vivo. Neurobiology of aging. vol 25. issue 10. 2004-12-15. PMID:15465624. |
peripheral administration of the aminopyridazine mw01-070c, beginning 3 weeks after the start of intracerebroventricular infusion of human abeta1-42, decreased the number of activated astrocytes and microglia and the levels of proinflammatory cytokines interleukin-1beta, tumor necrosis factor-alpha and s100b in the hippocampus. |
2004-12-15 |
2023-08-12 |
human |