| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C K Petito, B Roberts, J D Cantando, A Rabinstein, R Dunca. Hippocampal injury and alterations in neuronal chemokine co-receptor expression in patients with AIDS. Journal of neuropathology and experimental neurology. vol 60. issue 4. 2001-04-19. PMID:11305873. |
hive cases had increased neuronal cxcr4 and decreased neuronal ccr5 expression as well as increased numbers of hippocampal gfap-positive astrocytes and ln3-positive microglia. |
2001-04-19 |
2023-08-12 |
Not clear |
| P J Kingham, J M Pococ. Microglial secreted cathepsin B induces neuronal apoptosis. Journal of neurochemistry. vol 76. issue 5. 2001-04-05. PMID:11238732. |
conditioned medium from cga exposed microglia was neurotoxic to the ht22 hippocampal cell line and to primary cultures of cerebellar granule neurones. |
2001-04-05 |
2023-08-12 |
Not clear |
| H J Bidmon, B Emde, E Oermann, R Kubitz, O W Witte, K Zille. Heme oxygenase-1 (HSP-32) and heme oxygenase-2 induction in neurons and glial cells of cerebral regions and its relation to iron accumulation after focal cortical photothrombosis. Experimental neurology. vol 168. issue 1. 2001-03-29. PMID:11170717. |
ho-1-positive astrocytes and microglia occurred in ipsilateral cortex, corpus callosum, hippocampus, striatum, and thalamic nuclei. |
2001-03-29 |
2023-08-12 |
rat |
| S W Barger, A S Basil. Activation of microglia by secreted amyloid precursor protein evokes release of glutamate by cystine exchange and attenuates synaptic function. Journal of neurochemistry. vol 76. issue 3. 2001-03-15. PMID:11158256. |
conditioned medium from primary rat microglia activated by sapp caused a calcium elevation in hippocampal neurons, whereas medium from untreated microglia did not. |
2001-03-15 |
2023-08-12 |
rat |
| C Eriksson, L P Zou, S Ahlenius, B Winblad, M Schultzber. Inhibition of kainic acid induced expression of interleukin-1 beta and interleukin-1 receptor antagonist mRNA in the rat brain by NMDA receptor antagonists. Brain research. Molecular brain research. vol 85. issue 1-2. 2001-03-08. PMID:11146112. |
results in a transient expression of il-1 beta and il-1ra mrna, mainly in microglia, in regions showing neurodegeneration such as the hippocampus, thalamus, amygdala, and certain cortical regions. |
2001-03-08 |
2023-08-12 |
rat |
| S E Arnold, L Y Han, C M Clark, M Grossman, J Q Trojanowsk. Quantitative neurohistological features of frontotemporal degeneration. Neurobiology of aging. vol 21. issue 6. 2001-02-15. PMID:11124442. |
we found that ftd frontal and hippocampal regions exhibited marked neuron loss, abundant ubiquitin-immunoreactive (ir) dystrophic neurites, gfap-ir astrocytes, and cd68-ir microglia, while calcarine cortex was spared. |
2001-02-15 |
2023-08-12 |
human |
| D Koczyk, B Oderfeld-Nowa. Long-term microglial and astroglial activation in the hippocampus of trimethyltin-intoxicated rat: stimulation of NGF and TrkA immunoreactivities in astroglia but not in microglia. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 18. issue 6. 2000-09-28. PMID:10884604. |
long-term microglial and astroglial activation in the hippocampus of trimethyltin-intoxicated rat: stimulation of ngf and trka immunoreactivities in astroglia but not in microglia. |
2000-09-28 |
2023-08-12 |
rat |
| E Aronica, E A van Vliet, O A Mayboroda, D Troost, F H da Silva, J A Gorte. Upregulation of metabotropic glutamate receptor subtype mGluR3 and mGluR5 in reactive astrocytes in a rat model of mesial temporal lobe epilepsy. The European journal of neuroscience. vol 12. issue 7. 2000-09-19. PMID:10947812. |
se resulted in hypertrophy of astrocytes and microglia activation throughout the hippocampus as revealed by immunolabelling studies. |
2000-09-19 |
2023-08-12 |
rat |
| M B Jensen, I V Hegelund, N D Lomholt, B Finsen, T Owen. IFNgamma enhances microglial reactions to hippocampal axonal degeneration. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 10. 2000-05-25. PMID:10804203. |
we have studied activation of hippocampal microglia to produce tnfalpha in response to transection of perforant path axons in sjl/j mice. |
2000-05-25 |
2023-08-12 |
mouse |
| B Hauss-Wegrzyniak, M G Vannucchi, G L Wen. Behavioral and ultrastructural changes induced by chronic neuroinflammation in young rats. Brain research. vol 859. issue 1. 2000-05-09. PMID:10720625. |
immunohistochemical staining found numerous highly activated microglia distributed throughout the cingulate gyrus, entorhinal cortex, hippocampus and dentate gyrus. |
2000-05-09 |
2023-08-12 |
rat |
| G G Skibo, I R Nikonenko, V L Savchenko, J A McKann. Microglia in organotypic hippocampal slice culture and effects of hypoxia: ultrastructure and lipocortin-1 immunoreactivity. Neuroscience. vol 96. issue 2. 2000-04-20. PMID:10683583. |
microglia in organotypic hippocampal slice culture and effects of hypoxia: ultrastructure and lipocortin-1 immunoreactivity. |
2000-04-20 |
2023-08-12 |
Not clear |
| G G Skibo, I R Nikonenko, V L Savchenko, J A McKann. Microglia in organotypic hippocampal slice culture and effects of hypoxia: ultrastructure and lipocortin-1 immunoreactivity. Neuroscience. vol 96. issue 2. 2000-04-20. PMID:10683583. |
lipocortin-1 immunocytochemistry was used to study the various cell forms of microglia that appear during organotypic hippocampal tissue culture, as well as in the in vitro toxic hypoxia model. |
2000-04-20 |
2023-08-12 |
Not clear |
| V Zujovic, J Benavides, X Vigé, C Carter, V Taupi. Fractalkine modulates TNF-alpha secretion and neurotoxicity induced by microglial activation. Glia. vol 29. issue 4. 2000-04-11. PMID:10652441. |
lps-activated microglia were neurotoxic when added to neuronal hippocampal culture, producing 20% neuronal death, as measured by neun-positive cell counting. |
2000-04-11 |
2023-08-12 |
rat |
| M P Flavin, G Zhao, L T H. Microglial tissue plasminogen activator (tPA) triggers neuronal apoptosis in vitro. Glia. vol 29. issue 4. 2000-04-11. PMID:10652444. |
we previously showed that conditioned medium (cm) harvested from peritoneal macrophages or from activated microglia triggered apoptosis in rat hippocampal neurons in culture. |
2000-04-11 |
2023-08-12 |
human |
| M P Flavin, G Zhao, L T H. Microglial tissue plasminogen activator (tPA) triggers neuronal apoptosis in vitro. Glia. vol 29. issue 4. 2000-04-11. PMID:10652444. |
quiescent microglia produced cm that did not disrupt hippocampal neurons. |
2000-04-11 |
2023-08-12 |
human |
| K Bulloch, M Sadamatsu, A Patel, B S McEwe. Calcitonin gene-related peptide immunoreactivity in the hippocampus and its relationship to cellular changes following exposure to trimethyltin. Journal of neuroscience research. vol 55. issue 4. 2000-03-29. PMID:10723055. |
we have specifically focused on comparing the changes in cgrp-ir with the pattern of apoptosis (via tunel staining), cell-cycle activation (ki67-ir), and in alteration in microglia (ox-42-ir) and astrocyte (ggfap-ir) immunocytochemistry in tmt-treated hippocampus. |
2000-03-29 |
2023-08-12 |
Not clear |
| K Bulloch, M Sadamatsu, A Patel, B S McEwe. Calcitonin gene-related peptide immunoreactivity in the hippocampus and its relationship to cellular changes following exposure to trimethyltin. Journal of neuroscience research. vol 55. issue 4. 2000-03-29. PMID:10723055. |
our results show a marked change in cgrp-ir in regions of the hippocampus that are temporally and anatomically correlated with the induction of apoptosis and activation of microglia, astrocyte, and the cell-cycle marker. |
2000-03-29 |
2023-08-12 |
Not clear |
| A Matsumoto, K Itoh, R Matsumot. A novel carboxypeptidase B that processes native beta-amyloid precursor protein is present in human hippocampus. The European journal of neuroscience. vol 12. issue 1. 2000-03-16. PMID:10651877. |
an immunohistochemical study showed that the protease is expressed in various neuronal perikarya, including those of pyramidal neurons of the hippocampus and ependymal-choroid plexus cells, and in a portion of the microglia of normal brains. |
2000-03-16 |
2023-08-12 |
human |
| S A Kotecha, L C Schlichte. A Kv1.5 to Kv1.3 switch in endogenous hippocampal microglia and a role in proliferation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 24. 2000-01-06. PMID:10594052. |
a kv1.5 to kv1.3 switch in endogenous hippocampal microglia and a role in proliferation. |
2000-01-06 |
2023-08-12 |
rat |
| S A Kotecha, L C Schlichte. A Kv1.5 to Kv1.3 switch in endogenous hippocampal microglia and a role in proliferation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 24. 2000-01-06. PMID:10594052. |
microglia were tissue-printed directly from the hippocampal region using brain slices from 5- to 14-d-old rats. |
2000-01-06 |
2023-08-12 |
rat |