| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L Ren, B Lubrich, K Biber, P J Gebicke-Haerte. Differential expression of inflammatory mediators in rat microglia cultured from different brain regions. Brain research. Molecular brain research. vol 65. issue 2. 1999-04-07. PMID:10064890. |
in this study, microglia were isolated from 2-4 week-old mixed cns cultures that had been prepared from neonatal rat diencephalon, tegmentum, hippocampus, cerebellum and cerebral cortex, and were investigated 24 h later. |
1999-04-07 |
2023-08-12 |
rat |
| L Ren, B Lubrich, K Biber, P J Gebicke-Haerte. Differential expression of inflammatory mediators in rat microglia cultured from different brain regions. Brain research. Molecular brain research. vol 65. issue 2. 1999-04-07. PMID:10064890. |
the results clearly show, that three of these mrnas (tnf-alpha, cd4, fcgamma receptor ii) are differentially expressed in microglia with hippocampal microglia displaying the highest levels of these mrnas. |
1999-04-07 |
2023-08-12 |
rat |
| J M Long, A N Kalehua, N J Muth, M E Calhoun, M Jucker, J M Hengemihle, D K Ingram, P R Mouto. Stereological analysis of astrocyte and microglia in aging mouse hippocampus. Neurobiology of aging. vol 19. issue 5. 1999-03-11. PMID:9880052. |
stereological analysis of astrocyte and microglia in aging mouse hippocampus. |
1999-03-11 |
2023-08-12 |
mouse |
| J M Long, A N Kalehua, N J Muth, M E Calhoun, M Jucker, J M Hengemihle, D K Ingram, P R Mouto. Stereological analysis of astrocyte and microglia in aging mouse hippocampus. Neurobiology of aging. vol 19. issue 5. 1999-03-11. PMID:9880052. |
to test the hypothesis that the number of microglia and astrocytes increase in the hippocampus during normal aging, unbiased stereological techniques were used to estimate total cell number in hippocampal subregions (ca1, dentate gyrus and hilus) of male c57bl/6j mice of different ages: 4-5 months, 13-14 months and 27-28 months. |
1999-03-11 |
2023-08-12 |
mouse |
| J M Long, A N Kalehua, N J Muth, M E Calhoun, M Jucker, J M Hengemihle, D K Ingram, P R Mouto. Stereological analysis of astrocyte and microglia in aging mouse hippocampus. Neurobiology of aging. vol 19. issue 5. 1999-03-11. PMID:9880052. |
no statistically significant age differences were found in the numbers of microglia or astrocytes in the hippocampal regions sampled. |
1999-03-11 |
2023-08-12 |
mouse |
| J M Long, A N Kalehua, N J Muth, M E Calhoun, M Jucker, J M Hengemihle, D K Ingram, P R Mouto. Stereological analysis of astrocyte and microglia in aging mouse hippocampus. Neurobiology of aging. vol 19. issue 5. 1999-03-11. PMID:9880052. |
these findings suggest that age-related increases in the total numbers of hippocampal microglia and astrocytes is not causal for observed age-related increases in cytokine response. |
1999-03-11 |
2023-08-12 |
mouse |
| J M Long, A N Kalehua, N J Muth, J M Hengemihle, M Jucker, M E Calhoun, D K Ingram, P R Mouto. Stereological estimation of total microglia number in mouse hippocampus. Journal of neuroscience methods. vol 84. issue 1-2. 1999-01-26. PMID:9821640. |
stereological estimation of total microglia number in mouse hippocampus. |
1999-01-26 |
2023-08-12 |
mouse |
| J M Long, A N Kalehua, N J Muth, J M Hengemihle, M Jucker, M E Calhoun, D K Ingram, P R Mouto. Stereological estimation of total microglia number in mouse hippocampus. Journal of neuroscience methods. vol 84. issue 1-2. 1999-01-26. PMID:9821640. |
in the present study, immunocytochemistry was combined with unbiased stereology to estimate the mean total number of microglia in dentate gyrus and ca1 regions of the mouse hippocampus. |
1999-01-26 |
2023-08-12 |
mouse |
| J M Long, A N Kalehua, N J Muth, J M Hengemihle, M Jucker, M E Calhoun, D K Ingram, P R Mouto. Stereological estimation of total microglia number in mouse hippocampus. Journal of neuroscience methods. vol 84. issue 1-2. 1999-01-26. PMID:9821640. |
the time required to determine total microglia number in both hippocampal sub-regions was approximately 6 h per mouse from stained sections. |
1999-01-26 |
2023-08-12 |
mouse |
| I Dalmau, B Finsen, J Zimmer, B González, B Castellan. Development of microglia in the postnatal rat hippocampus. Hippocampus. vol 8. issue 5. 1999-01-22. PMID:9825958. |
development of microglia in the postnatal rat hippocampus. |
1999-01-22 |
2023-08-12 |
rat |
| I Dalmau, B Finsen, J Zimmer, B González, B Castellan. Development of microglia in the postnatal rat hippocampus. Hippocampus. vol 8. issue 5. 1999-01-22. PMID:9825958. |
during the prenatal development of the hippocampus, microglial cell precursors progressively occur in all subfields in accordance with known ontogenetic gradients of the region (dalmau et al., j. comp. |
1999-01-22 |
2023-08-12 |
rat |
| I Dalmau, B Finsen, J Zimmer, B González, B Castellan. Development of microglia in the postnatal rat hippocampus. Hippocampus. vol 8. issue 5. 1999-01-22. PMID:9825958. |
the present study follows the regional distribution of these microglial cell precursors and their morphological differentiation in the rat hippocampus from birth to postnatal (p) day 18. |
1999-01-22 |
2023-08-12 |
rat |
| I Dalmau, B Finsen, J Zimmer, B González, B Castellan. Development of microglia in the postnatal rat hippocampus. Hippocampus. vol 8. issue 5. 1999-01-22. PMID:9825958. |
the appearance of microglia in the hippocampal subregions and differentiation of cell precursors into adult microglia occur earlier at temporal levels than at septal levels. |
1999-01-22 |
2023-08-12 |
rat |
| I Dalmau, B Finsen, J Zimmer, B González, B Castellan. Development of microglia in the postnatal rat hippocampus. Hippocampus. vol 8. issue 5. 1999-01-22. PMID:9825958. |
the differentiation and appearance of microglia in the various hippocampal and dentate subregions often correspond to the developmental stage of intrinsic and extrinsic afferent nerve fiber projections. |
1999-01-22 |
2023-08-12 |
rat |
| A Hagendorff, C Dettmers, P Danos, M Hümmelgen, C Vahlhaus, C Martin, G Heusch, B Lüderit. Cerebral vasoconstriction during sustained ventricular tachycardia induces an ischemic stress response of brain tissue in rats. Journal of molecular and cellular cardiology. vol 30. issue 10. 1998-12-16. PMID:9826520. |
hsp 72 and activated microglia were found in hippocampal regions only after mht-vt (p<0.05 v control and mhh). |
1998-12-16 |
2023-08-12 |
rat |
| E J Beilharz, V C Russo, G Butler, N L Baker, B Connor, E S Sirimanne, M Dragunow, G A Werther, P D Gluckman, C E Williams, A Scheepen. Co-ordinated and cellular specific induction of the components of the IGF/IGFBP axis in the rat brain following hypoxic-ischemic injury. Brain research. Molecular brain research. vol 59. issue 2. 1998-10-28. PMID:9729323. |
igfbp-2 mrna was strongly induced in reactive astrocytes throughout the injured hemisphere, and igfbp-3 and igfbp-5 mrna were moderately induced in reactive microglia and neurones of the injured hippocampus, respectively. |
1998-10-28 |
2023-08-12 |
rat |
| A Bruccoleri, H Brown, G J Harr. Cellular localization and temporal elevation of tumor necrosis factor-alpha, interleukin-1 alpha, and transforming growth factor-beta 1 mRNA in hippocampal injury response induced by trimethyltin. Journal of neurochemistry. vol 71. issue 4. 1998-10-14. PMID:9751191. |
to study the role of cytokines in the early stages of brain injury, we examined alterations in the 17-day-old mouse hippocampus during trimethyltin-induced neurodegeneration characterized by neuronal necrosis, microglia activation in the dentate, and astrocyte reactivity throughout the hippocampus. |
1998-10-14 |
2023-08-12 |
mouse |
| Y Matsuoka, Y Kitamura, M Okazaki, J Kakimura, I Tooyama, H Kimura, T Taniguch. Kainic acid induction of heme oxygenase in vivo and in vitro. Neuroscience. vol 85. issue 4. 1998-10-01. PMID:9681959. |
in the rat hippocampus, cells expressing heme oxygenase-1 in vivo were predominately microglia and only a few astrocytes. |
1998-10-01 |
2023-08-12 |
rat |
| B M Bradt, W P Kolb, N R Coope. Complement-dependent proinflammatory properties of the Alzheimer's disease beta-peptide. The Journal of experimental medicine. vol 188. issue 3. 1998-09-08. PMID:9687521. |
large numbers of neuritic plaques (np), largely composed of a fibrillar insoluble form of the beta-amyloid peptide (abeta), are found in the hippocampus and neocortex of alzheimer's disease (ad) patients in association with damaged neuronal processes, increased numbers of activated astrocytes and microglia, and several proteins including the components of the proinflammatory complement system. |
1998-09-08 |
2023-08-12 |
Not clear |
| D L Price, P C Wong, D R Borchelt, C A Pardo, G Thinakaran, A P Doan, M K Lee, L J Martin, S S Sisodi. Amyotrophic lateral sclerosis and Alzheimer disease. Lessons from model systems. Revue neurologique. vol 153. issue 8-9. 1998-08-10. PMID:9683997. |
models of ad include: aged monkeys that show both cognitive/memory deficits and cellular abnormalities (amyloid deposition/cytoskeletal abnormalities of neurons) in cortex and hippocampus; and tg mice that express mutant human fad-linked genes (i.e., app and ps1) and show increased levels of a.42, amyloid deposits, dystrophic neurites, and local responses of astrocytes and microglia. |
1998-08-10 |
2023-08-12 |
mouse |