All Relations between hypertrophic and matrix compartment

Publication Sentence Publish Date Extraction Date Species
Emilio Satoshi Hara, Masahiro Okada, Noriyuki Nagaoka, Takako Hattori, Takuo Kuboki, Takayoshi Nakano, Takuya Matsumot. Bioinspired Mineralization Using Chondrocyte Membrane Nanofragments. ACS biomaterials science & engineering. vol 4. issue 2. 2021-01-11. PMID:33418750. instead, chondrocyte membrane nanofragments were found in the fibrous matrix surrounding the hypertrophic chondrocytes. 2021-01-11 2023-08-13 mouse
Jianlin Feng, Maria K Armillei, Albert S Yu, Bruce T Liang, Loren W Runnels, Lixia Yu. Ca Journal of cardiovascular development and disease. vol 6. issue 4. 2021-01-10. PMID:31547577. ca cardiac fibrosis is the excessive deposition of extracellular matrix proteins by cardiac fibroblasts and myofibroblasts, and is a hallmark feature of most heart diseases, including arrhythmia, hypertrophy, and heart failure. 2021-01-10 2023-08-13 Not clear
Behzad Javaheri, Soraia P Caetano-Silva, Ioannis Kanakis, George Bou-Gharios, Andrew A Pitsillide. The Chondro-Osseous Continuum: Is It Possible to Unlock the Potential Assigned Within? Frontiers in bioengineering and biotechnology. vol 6. 2021-01-09. PMID:29619368. endochondral ossification (eo), by which long bones of the axial skeleton form, is a tightly regulated process involving chondrocyte maturation with successive stages of proliferation, maturation, and hypertrophy, accompanied by cartilage matrix synthesis, calcification, and angiogenesis, followed by osteoblast-mediated ossification. 2021-01-09 2023-08-13 Not clear
Bishara S Atiye. Nonsurgical Management of Hypertrophic Scars: Evidence-Based Therapies, Standard Practices, and Emerging Methods. Aesthetic plastic surgery. vol 44. issue 4. 2021-01-06. PMID:32766921. hypertrophic scars, resulting from alterations in the normal processes of cutaneous wound healing, are characterized by proliferation of dermal tissue with excessive deposition of fibroblast-derived extracellular matrix proteins, especially collagen, over long periods, and by persistent inflammation and fibrosis. 2021-01-06 2023-08-13 Not clear
Mazaher Gholipourmalekabadi, Sadjad Khosravimelal, Zeinab Nokhbedehghan, Marzieh Sameni, Vahid Jajarmi, Aleksandra M Urbanska, Hadi Mirzaei, Maryam Salimi, Narendra Pal Singh Chauhan, Mohammadmahdi Mobaraki, Rui L Reis, Ali Samadikuchaksaraei, Subhas C Kund. Modulation of Hypertrophic Scar Formation Using Amniotic Membrane/Electrospun Silk Fibroin Bilayer Membrane in a Rabbit Ear Model. ACS biomaterials science & engineering. vol 5. issue 3. 2021-01-06. PMID:33405623. hypertrophic scarring is a dermal disorder resulting from collagen and other extra cellular matrix protein depositions following the deep trauma, severe burn injury, and surgery incisions. 2021-01-06 2023-08-13 human
Heather Fairfield, Samantha Costa, Victoria DeMambro, Celine Schott, Janaina Da Silva Martins, Mathieu Ferron, Calvin Vary, Michaela R Reaga. Targeting Bone Cells During Sexual Maturation Reveals Sexually Dimorphic Regulation of Endochondral Ossification. JBMR plus. vol 4. issue 11. 2020-11-21. PMID:33210065. in endochondral ossification, chondroblasts become embedded in their matrix and become chondrocytes, which are mature cells that continue to proliferate, eventually becoming hypertrophic. 2020-11-21 2023-08-13 mouse
Heather Fairfield, Samantha Costa, Victoria DeMambro, Celine Schott, Janaina Da Silva Martins, Mathieu Ferron, Calvin Vary, Michaela R Reaga. Targeting Bone Cells During Sexual Maturation Reveals Sexually Dimorphic Regulation of Endochondral Ossification. JBMR plus. vol 4. issue 11. 2020-11-21. PMID:33210065. hypertrophic chondrocytes produce cartilage that is then resorbed by osteoclasts prior to bone matrix replacement via osteoblasts. 2020-11-21 2023-08-13 mouse
Luis Hortells, Iñigo Valiente-Alandi, Zachary M Thomas, Emma J Agnew, Dan J Schnell, Allen J York, Ronald J Vagnozzi, Evan C Meyer, Jeffery D Molkentin, Katherine E Yutze. A specialized population of Periostin-expressing cardiac fibroblasts contributes to postnatal cardiomyocyte maturation and innervation. Proceedings of the National Academy of Sciences of the United States of America. vol 117. issue 35. 2020-11-13. PMID:32817558. during the postnatal period in mammals, the cardiac muscle transitions from hyperplasic to hypertrophic growth, the extracellular matrix (ecm) undergoes remodeling, and the heart loses regenerative capacity. 2020-11-13 2023-08-13 mouse
Amanda R Tucci, Francisco O R de Oliveira, Guilherme C Lechuga, Gabriel M Oliveira, Ana Carolina Eleuterio, Liliane B de Mesquita, Priscila S G Farani, Constança Britto, Otacílio C Moreira, Mirian Claudia S Pereir. Role of FAK signaling in chagasic cardiac hypertrophy. The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases. vol 24. issue 5. 2020-11-09. PMID:32931757. c57bl/6 mice infected with t. cruzi (brazil strain) were evaluated for electrocardiographic (ecg) changes, plasma levels of endothelin-1 (et-1) and activation of signaling pathways involved in cardiac hypertrophy, including fak and erk1/2, as well as expression of hypertrophy marker and components of the extracellular matrix in the different stages of t. cruzi infection (60-210 dpi). 2020-11-09 2023-08-13 mouse
Margot Neefjes, Arjan P M van Caam, Peter M van der Kraa. Transcription Factors in Cartilage Homeostasis and Osteoarthritis. Biology. vol 9. issue 9. 2020-10-28. PMID:32937960. in this review, we discuss crucial transcription factors for extracellular matrix metabolism, chondrocyte hypertrophy, chondrocyte senescence, and autophagy in chondrocytes. 2020-10-28 2023-08-13 Not clear
Qiyu Liu, Zhe Yang, Ning Ma, Weixing Wang, Yangqun L. MMP-2 and TIMP-2 expression, quantitative analysis and biomechanical changes in scar hypertrophy after autologous free transplantation of rabbit oral mucosa and scrotal skin. Saudi journal of biological sciences. vol 27. issue 11. 2020-10-28. PMID:33100864. this study aimed to investigate the long-term scar hypertrophy in the rabbit transplanted oral mucosa and scrotal skin with changed matrix environment, as well as the scar location expression, quantitative analysis of matrix metalloproteinase-2 (mmp-2) and tissue inhibitor of metalloproteinase-2 (timp-2) and biomechanical changes in the transplanted tissues. 2020-10-28 2023-08-13 rabbit
Kirsty L Culley, Samantha G Lessard, Jordan D Green, Justin Quinn, Jun Chang, Tyler Khilnani, Elisabeth B Wondimu, Cecilia L Dragomir, Kenneth B Marcu, Mary B Goldring, Miguel Oter. Inducible knockout of CHUK/IKKα in adult chondrocytes reduces progression of cartilage degradation in a surgical model of osteoarthritis. Scientific reports. vol 9. issue 1. 2020-10-27. PMID:31222033. chuk/ikkα contributes to collagenase-driven extracellular matrix remodeling and chondrocyte hypertrophic differentiation in vitro, in a kinase-independent manner. 2020-10-27 2023-08-13 Not clear
Kirsty L Culley, Samantha G Lessard, Jordan D Green, Justin Quinn, Jun Chang, Tyler Khilnani, Elisabeth B Wondimu, Cecilia L Dragomir, Kenneth B Marcu, Mary B Goldring, Miguel Oter. Inducible knockout of CHUK/IKKα in adult chondrocytes reduces progression of cartilage degradation in a surgical model of osteoarthritis. Scientific reports. vol 9. issue 1. 2020-10-27. PMID:31222033. these processes contribute to osteoarthritis (oa), where chondrocytes experience a phenotypic shift towards hypertrophy concomitant with abnormal matrix remodeling. 2020-10-27 2023-08-13 Not clear
Lorenzo R Sewanan, Jonas Schwan, Jonathan Kluger, Jinkyu Park, Daniel L Jacoby, Yibing Qyang, Stuart G Campbel. Extracellular Matrix From Hypertrophic Myocardium Provokes Impaired Twitch Dynamics in Healthy Cardiomyocytes. JACC. Basic to translational science. vol 4. issue 4. 2020-10-27. PMID:31468004. extracellular matrix from hypertrophic myocardium provokes impaired twitch dynamics in healthy cardiomyocytes. 2020-10-27 2023-08-13 mouse
Julie K Nguyen, Evan Austin, Alisen Huang, Andrew Mamalis, Jared Jagde. The IL-4/IL-13 axis in skin fibrosis and scarring: mechanistic concepts and therapeutic targets. Archives of dermatological research. vol 312. issue 2. 2020-10-27. PMID:31493000. skin fibrosis, characterized by excessive fibroblast proliferation and extracellular matrix deposition in the dermis, is the histopathologic hallmark of dermatologic diseases such as systemic sclerosis, hypertrophic scars, and keloids. 2020-10-27 2023-08-13 Not clear
Kelsie E Oatmen, Elizabeth Cull, Francis G Spinal. Heart failure as interstitial cancer: emergence of a malignant fibroblast phenotype. Nature reviews. Cardiology. vol 17. issue 8. 2020-10-26. PMID:31686012. in animal models, a major factor driving progression from pressure-overload hypertrophy (poh) to hfpef is the activation and proliferation of an abnormal fibroblast phenotype that is resistant to apoptosis, degrades normal stromal matrix and is replaced with a fibrotic matrix structure. 2020-10-26 2023-08-13 Not clear
Fumiko Yano, Shinsuke Ohba, Yasutaka Murahashi, Sakae Tanaka, Taku Saito, Ung-Il Chun. Runx1 contributes to articular cartilage maintenance by enhancement of cartilage matrix production and suppression of hypertrophic differentiation. Scientific reports. vol 9. issue 1. 2020-10-14. PMID:31113964. runx1 contributes to articular cartilage maintenance by enhancement of cartilage matrix production and suppression of hypertrophic differentiation. 2020-10-14 2023-08-13 Not clear
Weike Feng, Yue Zhao, Xiaotong Song, Yuan Wang, Qian Chen, Haijun Zhao, Guangying Lu, Hongyan Yuan, Zhichun Wu, Huayun Y. Zi Shen Huo Luo Formula Prevents Aldosterone-Induced Cardiomyocyte Hypertrophy and Cardiac Fibroblast Proliferation by Regulating the Striatin-Mediated MR/EGFR/ERK Signaling Pathway. Evidence-based complementary and alternative medicine : eCAM. vol 2020. 2020-10-06. PMID:33014117. excessive aldosterone can lead to myocardial extracellular matrix collagen proliferation, fibrosis, and cardiomyocyte hypertrophy and aggravate maladaptive remodeling. 2020-10-06 2023-08-13 rat
Danyang Zhao, Yu Wang, Chao Du, Shengzhou Shan, Yifan Zhang, Zijing Du, Dong Ha. Honokiol Alleviates Hypertrophic Scar by Targeting Transforming Growth Factor-β/Smad2/3 Signaling Pathway. Frontiers in pharmacology. vol 8. 2020-10-01. PMID:28469575. hypertrophic scar (hps) presents as excessive extracellular matrix deposition and abnormal function of fibroblasts. 2020-10-01 2023-08-13 Not clear
Melissa A Lyle, Jonathan P Davis, Frank V Brozovic. Regulation of Pulmonary Vascular Smooth Muscle Contractility in Pulmonary Arterial Hypertension: Implications for Therapy. Frontiers in physiology. vol 8. 2020-10-01. PMID:28878690. there are two primary components that produce pulmonary arterial hypertension (pah); aberrant structural changes (smooth muscle cell proliferation, smooth muscle cell hypertrophy, and the deposition of matrix proteins within the media of pulmonary arterial vessels), and excess vasoconstriction. 2020-10-01 2023-08-13 Not clear