| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chen Fan, Samir El Andaloussi, Taavi Lehto, Kiat Whye Kong, Yiqi Seo. Smad‑binding decoy reduces extracellular matrix expression in human hypertrophic scar fibroblasts. Molecular medicine reports. vol 22. issue 6. 2021-05-13. PMID:33173952. |
smad‑binding decoy reduces extracellular matrix expression in human hypertrophic scar fibroblasts. |
2021-05-13 |
2023-08-13 |
human |
| Vivek Jeyakumar, Nedaa Amraish, Eugenia Niculescu-Morsza, Christoph Bauer, Dieter Pahr, Stefan Nehre. Decellularized Cartilage Extracellular Matrix Incorporated Silk Fibroin Hybrid Scaffolds for Endochondral Ossification Mediated Bone Regeneration. International journal of molecular sciences. vol 22. issue 8. 2021-05-12. PMID:33919985. |
hbmsc's were primed two weeks for chondrogenesis, followed by six weeks for hypertrophy onto hybrid cd-ecm/sf or sf alone scaffolds and evaluated for the mineralized matrix formation in vitro. |
2021-05-12 |
2023-08-13 |
Not clear |
| Xinhang Dong, Mingzi Zhang, Xiaolei Ji. The Mechanism of miR-222 Targets Matrix Metalloproteinase 1 in Regulating Fibroblast Proliferation in Hypertrophic Scars. Aesthetic plastic surgery. 2021-05-08. PMID:33963427. |
the mechanism of mir-222 targets matrix metalloproteinase 1 in regulating fibroblast proliferation in hypertrophic scars. |
2021-05-08 |
2023-08-13 |
Not clear |
| Ying Kui Zhong, Bao Lan Lu, Si Yun Huang, Yu Jun Chen, Zi Ping Li, Jordi Rimola, Xue Hua L. Cross-sectional imaging for assessing intestinal fibrosis in Crohn's disease. Journal of digestive diseases. vol 21. issue 6. 2021-04-30. PMID:32418328. |
excessive deposition of extracellular matrix components in the submucosa and smooth muscle hypertrophy or hyperplasia are the main features of fibrosis in cd. |
2021-04-30 |
2023-08-13 |
Not clear |
| Zachary M Working, Elizabeth R Morris, Jiun Chiun Chang, Ryan F Coghlan, Brian Johnstone, Theodore Miclau, William A Horton, Chelsea S Bahne. A quantitative serum biomarker of circulating collagen X effectively correlates with endochondral fracture healing. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. vol 39. issue 1. 2021-04-30. PMID:32533783. |
prior to converting to the bone, cartilage undergoes hypertrophic maturation, characterized by the deposition of a provisional collagen x matrix. |
2021-04-30 |
2023-08-13 |
mouse |
| Kathrin Maly, Enrique Andres Sastre, Eric Farrell, Andrea Meurer, Frank Zauck. COMP and TSP-4: Functional Roles in Articular Cartilage and Relevance in Osteoarthritis. International journal of molecular sciences. vol 22. issue 5. 2021-04-29. PMID:33668140. |
the usually quiescent chondrocytes become reactivated and accumulate in cell clusters, become hypertrophic, and intensively produce not only degrading enzymes, but also ecm proteins, like the cartilage oligomeric matrix protein (comp) and thrombospondin-4 (tsp-4). |
2021-04-29 |
2023-08-13 |
Not clear |
| Yi Zhang, Wei-Long Hong, Zhi-Ming Li, Qi-Yu Zhang, Kang Zen. The Mechanism of miR-222 Targets Matrix Metalloproteinase 1 in Regulating Fibroblast Proliferation in Hypertrophic Scars. Aesthetic plastic surgery. vol 45. issue 2. 2021-04-19. PMID:32350561. |
the mechanism of mir-222 targets matrix metalloproteinase 1 in regulating fibroblast proliferation in hypertrophic scars. |
2021-04-19 |
2023-08-13 |
Not clear |
| Yanping Wei, Tingting Wang, Ningning Zhang, Yunyun Ma, Siji Shi, Ruxing Zhang, Xianzhao Zheng, Lindong Zha. LncRNA TRHDE-AS1 inhibit the scar fibroblasts proliferation via miR-181a-5p/PTEN axis. Journal of molecular histology. vol 52. issue 2. 2021-04-17. PMID:33675502. |
hypertrophic scar (hs), a fibroproliferative disorder caused by abnormal wound healing after skin injury, which is characterized by excessive deposition of extracellular matrix and invasive growth of fibroblasts. |
2021-04-17 |
2023-08-13 |
Not clear |
| Gabriela S Kronemberger, Gisele M L Dalmônico, André L Rossi, Paulo Emílio Correa Leite, Antonio M Saraiva, Anderson Beatrici, Karina Ribeiro Silva, José Mauro Granjeiro, Leandra Santos Baptist. Scaffold- and serum-free hypertrophic cartilage tissue engineering as an alternative approach for bone repair. Artificial organs. vol 44. issue 7. 2021-04-12. PMID:31950507. |
human adipose stem/stromal cell (asc) spheroids were used as a serum-free in vitro model to recapitulate the molecular events and extracellular matrix organization that orchestrate a hypertrophic cartilage phenotype. |
2021-04-12 |
2023-08-13 |
human |
| Danying Wang, Bo Che. The Mechanism of miR-222 Targets Matrix Metalloproteinase 1 in Regulating Fibroblast Proliferation in Hypertrophic Scars. Aesthetic plastic surgery. 2021-03-26. PMID:33768305. |
the mechanism of mir-222 targets matrix metalloproteinase 1 in regulating fibroblast proliferation in hypertrophic scars. |
2021-03-26 |
2023-08-13 |
Not clear |
| Jinxia Zhang, Zhikuan Xia, Shuanglin Zhou, Wanting Luo, Zhuoying Peng, Rongya Yan. Effect of Artesunate Combined With Fractional CO Lasers in surgery and medicine. 2021-03-18. PMID:33644924. |
effect of artesunate combined with fractional co hypertrophic scar (hs), a common complication in wound healing, is characterized by the disarrangement of collagen, fibers, and extracellular matrix. |
2021-03-18 |
2023-08-13 |
Not clear |
| Marietta Herrmann, Klaus Engelke, Regina Ebert, Sigrid Müller-Deubert, Maximilian Rudert, Fani Ziouti, Franziska Jundt, Dieter Felsenberg, Franz Jako. Interactions between Muscle and Bone-Where Physics Meets Biology. Biomolecules. vol 10. issue 3. 2021-03-17. PMID:32164381. |
this may result in the initiation of bone formation, muscle hypertrophy, and the enhanced production of extracellular matrix constituents, adhesion molecules, and cytoskeletal elements. |
2021-03-17 |
2023-08-13 |
Not clear |
| Yuyan Pan, Zhiwei Chen, Fazhi Qi, Jiaqi Li. Identification of drug compounds for keloids and hypertrophic scars: drug discovery based on text mining and DeepPurpose. Annals of translational medicine. vol 9. issue 4. 2021-03-13. PMID:33708974. |
keloids (kl) and hypertrophic scars (hs) are forms of abnormal cutaneous scarring characterized by excessive deposition of extracellular matrix and fibroblast proliferation. |
2021-03-13 |
2023-08-13 |
Not clear |
| Zhiqiang Li, Pengtao Wang, Jie Zhang, Dongkui Zha. MicroRNA-497-5p downregulation inhibits cell viability, reduces extracellular matrix deposition and induces apoptosis in human hyperplastic scar fibroblasts by regulating Smad7. Experimental and therapeutic medicine. vol 21. issue 4. 2021-03-10. PMID:33680106. |
hypertrophic scars (hss) are characterized by excessive extracellular matrix deposition and excessive growth of dense fibrous tissues. |
2021-03-10 |
2023-08-13 |
human |
| Ugo E Pazzaglia, Marcella Reguzzoni, Lavinia Casati, Valeria Sibilia, Guido Zarattini, Mario Raspant. New morphological evidence of the 'fate' of growth plate hypertrophic chondrocytes in the general context of endochondral ossification. Journal of anatomy. vol 236. issue 2. 2021-03-09. PMID:31820452. |
furthermore, the study provided evidence that the metaphyseal capillaries could advance inside the columns of stacked hypertrophic chondrocytes (delimited by the intercolumnar septa) without the need for calcified matrix resorption because the thin transverse septa between the stacked chondrocyte (below the mineral deposition line) were not calcified. |
2021-03-09 |
2023-08-13 |
Not clear |
| Xuanye Bi, Chengzhi Yang, Yunhu Song, Jiansong Yuan, Jingang Cui, Fenghuan Hu, Shubin Qia. Matrix Metalloproteinases Increase Because of Hypoperfusion in Obstructive Hypertrophic Cardiomyopathy. The Annals of thoracic surgery. vol 111. issue 3. 2021-03-09. PMID:32738221. |
matrix metalloproteinases increase because of hypoperfusion in obstructive hypertrophic cardiomyopathy. |
2021-03-09 |
2023-08-13 |
Not clear |
| Monika Szepes, Anna Melchert, Julia Dahlmann, Jan Hegermann, Christopher Werlein, Danny Jonigk, Axel Haverich, Ulrich Martin, Ruth Olmer, Ina Gru. Dual Function of iPSC-Derived Pericyte-Like Cells in Vascularization and Fibrosis-Related Cardiac Tissue Remodeling In Vitro. International journal of molecular sciences. vol 21. issue 23. 2021-03-05. PMID:33255686. |
myocardial interstitial fibrosis (mif) is characterized by excessive extracellular matrix (ecm) deposition, increased myocardial stiffness, functional weakening, and compensatory cardiomyocyte (cm) hypertrophy. |
2021-03-05 |
2023-08-13 |
human |
| Sara Al-Ghadban, India A Pursell, Zaidmara T Diaz, Karen L Herbst, Bruce A Bunnel. 3D Spheroids Derived from Human Lipedema ASCs Demonstrated Similar Adipogenic Differentiation Potential and ECM Remodeling to Non-Lipedema ASCs In Vitro. International journal of molecular sciences. vol 21. issue 21. 2021-03-01. PMID:33171717. |
in lipedema, both inflammation and hypoxia influence the expansion and differentiation of ascs, resulting in hypertrophic adipocytes and deposition of collagen, a primary component of the extracellular matrix (ecm). |
2021-03-01 |
2023-08-13 |
human |
| Marlies Corvelyn, Nathalie De Beukelaer, Robin Duelen, Jorieke Deschrevel, Anja Van Campenhout, Sandra Prinsen, Ghislaine Gayan-Ramirez, Karen Maes, Guido Weide, Kaat Desloovere, Maurilio Sampaolesi, Domiziana Costamagn. Muscle Microbiopsy to Delineate Stem Cell Involvement in Young Patients: A Novel Approach for Children With Cerebral Palsy. Frontiers in physiology. vol 11. 2021-02-26. PMID:32848872. |
previous research reported altered muscle properties, such as reduced volume and satellite cell (sc) numbers and hypertrophic extracellular matrix compared to typically developing (td) children (>10 years). |
2021-02-26 |
2023-08-13 |
human |
| Soumya Maity, Falguni Das, Balakuntalam S Kasinath, Nandini Ghosh-Choudhury, Goutam Ghosh Choudhur. TGFβ acts through PDGFRβ to activate mTORC1 via the Akt/PRAS40 axis and causes glomerular mesangial cell hypertrophy and matrix protein expression. The Journal of biological chemistry. vol 295. issue 42. 2021-02-23. PMID:32732288. |
tgfβ acts through pdgfrβ to activate mtorc1 via the akt/pras40 axis and causes glomerular mesangial cell hypertrophy and matrix protein expression. |
2021-02-23 |
2023-08-13 |
mouse |