| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Maryam Sarbishegi, Fereshteh Mehraein, Mansooreh Soleiman. Antioxidant role of oleuropein on midbrain and dopaminergic neurons of substantia nigra in aged rats. Iranian biomedical journal. vol 18. issue 1. 2014-08-28. PMID:24375158. |
antioxidant role of oleuropein on midbrain and dopaminergic neurons of substantia nigra in aged rats. |
2014-08-28 |
2023-08-12 |
rat |
| Juan Segura-Aguilar, Irmgard Paris, Patricia Muñoz, Emanuele Ferrari, Luigi Zecca, Fabio A Zucc. Protective and toxic roles of dopamine in Parkinson's disease. Journal of neurochemistry. vol 129. issue 6. 2014-08-26. PMID:24548101. |
the molecular mechanisms causing the loss of dopaminergic neurons containing neuromelanin in the substantia nigra and responsible for motor symptoms of parkinson's disease are still unknown. |
2014-08-26 |
2023-08-12 |
Not clear |
| Biswarup Ghosh, Chen Zhang, George M Smit. Bridging between transplantation therapy and neurotrophic factors in Parkinson's disease. Frontiers in bioscience (Elite edition). vol 6. 2014-08-25. PMID:24896204. |
with increased understanding of growth and guidance molecule effecting dopaminergic neurons, it may be feasible to place transplants in the damaged substantia nigra and direct the growth of axons into target regions to reconstruction of midbrain dopamine (da) circuitry. |
2014-08-25 |
2023-08-13 |
Not clear |
| Daniel C Berwick, Kirsten Harve. The regulation and deregulation of Wnt signaling by PARK genes in health and disease. Journal of molecular cell biology. vol 6. issue 1. 2014-08-21. PMID:24115276. |
this debilitating disease is characterized by the progressive loss of a subset of midbrain dopaminergic neurones in the substantia nigra leading to typical extrapyramidal motor symptoms. |
2014-08-21 |
2023-08-12 |
Not clear |
| Jing Li, Li-Na Wang, Hong-Ling Xiao, Xia Li, Ji-Jun Yan. [Effect of electroacupuncture intervention on levels of SOD, GSH, GSH-Px, MDA, and apoptosis of dopaminergic neurons in substantia Nigra in rats with Parkinson's disease]. Zhen ci yan jiu = Acupuncture research. vol 39. issue 3. 2014-08-21. PMID:25069193. |
[effect of electroacupuncture intervention on levels of sod, gsh, gsh-px, mda, and apoptosis of dopaminergic neurons in substantia nigra in rats with parkinson's disease]. |
2014-08-21 |
2023-08-13 |
rat |
| Jing Li, Li-Na Wang, Hong-Ling Xiao, Xia Li, Ji-Jun Yan. [Effect of electroacupuncture intervention on levels of SOD, GSH, GSH-Px, MDA, and apoptosis of dopaminergic neurons in substantia Nigra in rats with Parkinson's disease]. Zhen ci yan jiu = Acupuncture research. vol 39. issue 3. 2014-08-21. PMID:25069193. |
to observe the effect of electroacupuncture (ea) on superoxide (sod), glutathione peroxidase (gsh-px) activity, contents of glutathione (gsh) and malondiadehyde (mda), and expression of tyrosine hydroxylase (th) and apoptosis of dopaminergic (da) neurons in substantia nigra of rats with parkinson's disease (pd). |
2014-08-21 |
2023-08-13 |
rat |
| Eun Hee Ahn, Dae Won Kim, Min Jea Shin, Young Nam Kim, Hye Ri Kim, Su Jung Woo, So Mi Kim, Duk-Soo Kim, Joon Kim, Jinseu Park, Won Sik Eum, Hyun Sook Hwang, Soo Young Cho. PEP-1-ribosomal protein S3 protects dopaminergic neurons in an MPTP-induced Parkinson's disease mouse model. Free radical biology & medicine. vol 55. 2014-08-20. PMID:23178948. |
parkinson's disease (pd) is a neurodegenerative disease characterized by a gradual loss of dopaminergic (da) neurons in the substantia nigra (sn) of the brain. |
2014-08-20 |
2023-08-12 |
mouse |
| Wenjiao Tai, Xuan Ye, Xiuqi Bao, Baozhong Zhao, Xiaoliang Wang, Dan Zhan. Inhibition of Src tyrosine kinase activity by squamosamide derivative FLZ attenuates neuroinflammation in both in vivo and in vitro Parkinson's disease models. Neuropharmacology. vol 75. 2014-08-19. PMID:23916477. |
flz treatment significantly improved the motor dysfunction of pd model rats induced by intra-nigral injection of lps and this beneficial effect of flz attributed to the inhibition of microglial over-activation and the protection on dopaminergic neurons in the substantia nigra (sn). |
2014-08-19 |
2023-08-12 |
rat |
| Yusuke Toyoda, Cihan Erkut, Francisco Pan-Montojo, Sebastian Boland, Martin P Stewart, Daniel J Müller, Wolfgang Wurst, Anthony A Hyman, Teymuras V Kurzchali. Products of the Parkinson's disease-related glyoxalase DJ-1, D-lactate and glycolate, support mitochondrial membrane potential and neuronal survival. Biology open. vol 3. issue 8. 2014-08-16. PMID:25063200. |
parkinson's disease is associated with mitochondrial decline in dopaminergic neurons of the substantia nigra. |
2014-08-16 |
2023-08-13 |
Not clear |
| Hiroyoshi Ariga, Kazuko Takahashi-Niki, Izumi Kato, Hiroshi Maita, Takeshi Niki, Sanae M M Iguchi-Arig. Neuroprotective function of DJ-1 in Parkinson's disease. Oxidative medicine and cellular longevity. vol 2013. 2014-08-13. PMID:23766857. |
parkinson's disease (pd) is caused by dopaminergic neuronal death in the substantia nigra, resulting in a reduced level of dopamine in the striatum. |
2014-08-13 |
2023-08-12 |
Not clear |
| Michaeline L Hebron, Irina Lonskaya, Charbel E-H Mouss. Tyrosine kinase inhibition facilitates autophagic SNCA/α-synuclein clearance. Autophagy. vol 9. issue 8. 2014-08-13. PMID:23787811. |
parkinson disease (pd) is a movement disorder characterized by death of dopaminergic substantia nigra (sn) neurons and brain accumulation of snca. |
2014-08-13 |
2023-08-12 |
mouse |
| Eunju Shin, James T Rogers, Paola Devoto, Anders Björklund, Manolo Cart. Noradrenaline neuron degeneration contributes to motor impairments and development of L-DOPA-induced dyskinesia in a rat model of Parkinson's disease. Experimental neurology. vol 257. 2014-08-13. PMID:24747357. |
parkinson's disease (pd) is characterized by progressive loss of dopaminergic (da) neurons in the substantia nigra. |
2014-08-13 |
2023-08-13 |
rat |
| Liviu-Gabriel Bodea, Yiner Wang, Bettina Linnartz-Gerlach, Jens Kopatz, Lasse Sinkkonen, Ruth Musgrove, Tony Kaoma, Arnaud Muller, Laurent Vallar, Donato A Di Monte, Rudi Balling, Harald Neuman. Neurodegeneration by activation of the microglial complement-phagosome pathway. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 25. 2014-08-12. PMID:24948809. |
we now demonstrate in vivo that repeated systemic challenge of mice over four consecutive days with bacterial lps maintained an elevated microglial inflammatory phenotype and induced loss of dopaminergic neurons in the substantia nigra. |
2014-08-12 |
2023-08-13 |
mouse |
| Christopher A Bates, Wei Zhen. Brain disposition of α-Synuclein: roles of brain barrier systems and implications for Parkinson's disease. Fluids and barriers of the CNS. vol 11. 2014-08-05. PMID:25093076. |
parkinson's disease (pd) is a neurodegenerative disorder characterized by the accumulation of α-synuclein (a-syn) into lewy body inclusions and the loss of dopaminergic neurons in the substantia nigra (sn). |
2014-08-05 |
2023-08-13 |
Not clear |
| Eung Seok Oh, Chaejeong Heo, Ji Seon Kim, Minah Suh, Young Hee Lee, Jong-Min Ki. Hyperspectral fluorescence imaging for cellular iron mapping in the in vitro model of Parkinson's disease. Journal of biomedical optics. vol 19. issue 5. 2014-08-04. PMID:24297062. |
parkinson's disease (pd) is characterized by progressive dopaminergic cell loss in the substantia nigra (sn) and elevated iron levels demonstrated by autopsy. |
2014-08-04 |
2023-08-12 |
Not clear |
| Martin Göttlich, Thomas F Münte, Marcus Heldmann, Meike Kasten, Johann Hagenah, Ulrike M Kräme. Altered resting state brain networks in Parkinson's disease. PloS one. vol 8. issue 10. 2014-08-02. PMID:24204812. |
parkinson's disease (pd) is a neurodegenerative disorder affecting dopaminergic neurons in the substantia nigra leading to dysfunctional cortico-striato-thalamic-cortical loops. |
2014-08-02 |
2023-08-12 |
Not clear |
| Eiko N Minakawa, Hodaka Yamakado, Atsushi Tanaka, Kengo Uemura, Shunichi Takeda, Ryosuke Takahash. Chicken DT40 cell line lacking DJ-1, the gene responsible for familial Parkinson's disease, displays mitochondrial dysfunction. Neuroscience research. vol 77. issue 4. 2014-08-01. PMID:24064392. |
parkinson's disease (pd) is the most common neurodegenerative movement disorder mainly due to gradual loss of dopaminergic neurons in the substantia nigra. |
2014-08-01 |
2023-08-12 |
mouse |
| Anna Czarnecka, Tomasz Lenda, Helena Domin, Jolanta Konieczny, Maria Smiałowska, Elżbieta Lorenc-Koc. Alterations in the expression of nNOS in the substantia nigra and subthalamic nucleus of 6-OHDA-lesioned rats: the effects of chronic treatment with l-DOPA and the nitric oxide donor, molsidomine. Brain research. vol 1541. 2014-07-28. PMID:24129225. |
degeneration of dopaminergic neurons in the substantia nigra (sn) in parkinson's disease leads to disturbances in the nitrergic transmission in the basal ganglia. |
2014-07-28 |
2023-08-12 |
rat |
| Bai-Yun Zeng, Sarah Salvage, Peter Jenne. Current development of acupuncture research in Parkinson's disease. International review of neurobiology. vol 111. 2014-07-28. PMID:24215921. |
in addition, acupuncture therapy slows cell death process and attenuates oxidative stress to dopaminergic neurons in the substantia nigra. |
2014-07-28 |
2023-08-12 |
Not clear |
| Miklos Antal, Brandon M Beneduce, Wade G Regeh. The substantia nigra conveys target-dependent excitatory and inhibitory outputs from the basal ganglia to the thalamus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 23. 2014-07-25. PMID:24899724. |
the substantia nigra (sn) consists of gabaergic neurons of the pars reticulata that inhibit thalamic neurons and provide the primary output of the bg, and dopaminergic neurons of the pars compacta that modulate thalamic excitability. |
2014-07-25 |
2023-08-13 |
mouse |