| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H Okamura, C Yokoyama, Y Ibat. Lateromedial gradient of the susceptibility of midbrain dopaminergic neurons to neonatal 6-hydroxydopamine toxicity. Experimental neurology. vol 136. issue 2. 1996-01-17. PMID:7498403. |
in all cases of intracisternal 6-ohda treatment, a9 dopaminergic neurons in the substantia nigra (sn) were much more vulnerable to death than more medially located a10 dopaminergic neurons. |
1996-01-17 |
2023-08-12 |
Not clear |
| W H Oertel, H Ellgrin. Parkinson's disease--medical education and psychosocial aspects. Patient education and counseling. vol 26. issue 1-3. 1996-01-11. PMID:7494758. |
the extent of the degeneration of dopaminergic neurons in the substantia nigra, present at the outbreak of the disease, is illustrated to the patient. |
1996-01-11 |
2023-08-12 |
Not clear |
| P M Laduro. Functional consequences of retrograde axonal transport of receptor-bound neurotensin. Trends in pharmacological sciences. vol 16. issue 10. 1996-01-04. PMID:7491711. |
the most compelling evidence that retrograde axonal transport of receptor-bound neuropeptide represents a long-distance signalling system in gene expression, discussed here by pierre laduron, comes from the recent observation that neurotensin injected in the striatum undergoes retrograde transport in dopaminergic neurones to the substantia nigra, where it induces in the cell bodies an increase of tyrosine hydroxylase mrna. |
1996-01-04 |
2023-08-12 |
Not clear |
| J S Parboosingh, M Rousseau, F Rogan, Z Amit, H Chertkow, W G Johnson, F Manganaro, H N Schipper, T J Curran, J Stoess. Absence of mutations in superoxide dismutase and catalase genes in patients with Parkinson's disease. Archives of neurology. vol 52. issue 12. 1996-01-04. PMID:7492289. |
parkinson's disease (pd) is an adult-onset, neurodegenerative disorder characterized by a selective loss of the dopaminergic cells of the substantia nigra and by progressive motor decline. |
1996-01-04 |
2023-08-12 |
Not clear |
| J S Parboosingh, M Rousseau, F Rogan, Z Amit, H Chertkow, W G Johnson, F Manganaro, H N Schipper, T J Curran, J Stoess. Absence of mutations in superoxide dismutase and catalase genes in patients with Parkinson's disease. Archives of neurology. vol 52. issue 12. 1996-01-04. PMID:7492289. |
studies have shown aberrant oxidative stress metabolism within the substantia nigra and other dopaminergic regions of the brain in patients with pd. |
1996-01-04 |
2023-08-12 |
Not clear |
| E Roy, P Y Côté, L Grégoire, A Parent, P J Bédar. Mesencephalic grafts partially restore normal nigral dynorphin levels in 6-hydroxydopamine-lesioned rats treated chronically with L-dihydroxyphenylalanine. Neuroscience. vol 66. issue 2. 1995-12-07. PMID:7477882. |
however, only animals displaying heavy loss of dopaminergic neurons in the substantia nigra pars compacta showed significant changes of dynorphin levels in the substantia nigra following drug treatment. |
1995-12-07 |
2023-08-12 |
rat |
| E M Tew, A Fearon, P N Anderson, G Burnstoc. Tyrosine hydroxylase-containing fibres extend from the rat corpus striatum into grafts of muscularis externa and myenteric plexus. Neuroscience letters. vol 194. issue 1-2. 1995-11-28. PMID:7478206. |
since the striatum receives profuse dopaminergic innervation from the substantia nigra, we have investigated whether central catecholaminergic neurons participated in the sprouting response and grew into grafts of adult myenteric plexus (surrounded by smooth muscle) implanted in the adult corpus striatum. |
1995-11-28 |
2023-08-12 |
rat |
| J Grenhoff, R A North, S W Johnso. Alpha 1-adrenergic effects on dopamine neurons recorded intracellularly in the rat midbrain slice. The European journal of neuroscience. vol 7. issue 8. 1995-11-28. PMID:7582125. |
electrophysiological and pharmacological parameters were used to identify cells as principal (presumably dopaminergic) neurons as opposed to secondary (presumably gabaergic) neurons in the substantia nigra zona compacta and the ventral tegmental area. |
1995-11-28 |
2023-08-12 |
rat |
| A Jaffer, G D van der Spuy, V A Russell, M Mintz, J J Taljaar. Activation of the subthalamic nucleus and pedunculopontine tegmentum: does it affect dopamine levels in the substantia nigra, nucleus accumbens and striatum? Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration. vol 4. issue 2. 1995-11-28. PMID:7583677. |
this study investigated whether death of substantia nigra (sn) dopaminergic neurons could be caused by the hyperactivity of afferent pathways resulting in the release of a toxic dose of excitatory amino acids in the sn. |
1995-11-28 |
2023-08-12 |
rat |
| M A Hossain, N Weine. Interactions of dopaminergic and GABAergic neurotransmission: impact of 6-hydroxydopamine lesions into the substantia nigra of rats. The Journal of pharmacology and experimental therapeutics. vol 275. issue 1. 1995-11-21. PMID:7562556. |
interactions of dopaminergic and gabaergic neurotransmission: impact of 6-hydroxydopamine lesions into the substantia nigra of rats. |
1995-11-21 |
2023-08-12 |
rat |
| C Marin, T N Chas. Effects of SCH 32615, an enkephalinase inhibitor, on D-1 and D-2 dopamine receptor-mediated behaviors. Neuropharmacology. vol 34. issue 6. 1995-11-14. PMID:7566505. |
striatal enkephalin-containing neurons receive dopaminergic inputs from the substantia nigra and project to the external segment of globus pallidus. |
1995-11-14 |
2023-08-12 |
Not clear |
| B A Faucheux, N Nillesse, P Damier, G Spik, A Mouatt-Prigent, A Pierce, B Leveugle, N Kubis, J J Hauw, Y Agi. Expression of lactoferrin receptors is increased in the mesencephalon of patients with Parkinson disease. Proceedings of the National Academy of Sciences of the United States of America. vol 92. issue 21. 1995-11-14. PMID:7568181. |
moreover, in the substantia nigra, the intensity of immunoreactivity on neurons and microvessels was higher for patients with higher nigral dopaminergic loss. |
1995-11-14 |
2023-08-12 |
human |
| S A Bayer, K V Wills, L C Triarhou, T Verina, J D Thomas, B Ghett. Selective vulnerability of late-generated dopaminergic neurons of the substantia nigra in weaver mutant mice. Proceedings of the National Academy of Sciences of the United States of America. vol 92. issue 20. 1995-10-27. PMID:7568088. |
selective vulnerability of late-generated dopaminergic neurons of the substantia nigra in weaver mutant mice. |
1995-10-27 |
2023-08-12 |
mouse |
| S A Bayer, K V Wills, L C Triarhou, T Verina, J D Thomas, B Ghett. Selective vulnerability of late-generated dopaminergic neurons of the substantia nigra in weaver mutant mice. Proceedings of the National Academy of Sciences of the United States of America. vol 92. issue 20. 1995-10-27. PMID:7568088. |
in homozygous weaver (wv/wv) mutant mice, nearly 50% of the dopaminergic substantia nigra neurons degenerate by postnatal day 20. |
1995-10-27 |
2023-08-12 |
mouse |
| H Sauer, C Rosenblad, A Björklun. Glial cell line-derived neurotrophic factor but not transforming growth factor beta 3 prevents delayed degeneration of nigral dopaminergic neurons following striatal 6-hydroxydopamine lesion. Proceedings of the National Academy of Sciences of the United States of America. vol 92. issue 19. 1995-10-23. PMID:7568047. |
we investigated the effects of intracerebral administration of gdnf and tgf-beta 3 on the delayed cell death of the dopamine neurons in the rat substantia nigra following 6-hydroxydopamine lesions of dopaminergic terminals in the striatum. |
1995-10-23 |
2023-08-12 |
human |
| L Medina, K D Anderson, E J Karle, A Reine. An ultrastructural double-label immunohistochemical study of the enkephalinergic input to dopaminergic neurons of the substantia nigra in pigeons. The Journal of comparative neurology. vol 357. issue 3. 1995-10-19. PMID:7673476. |
an ultrastructural double-label immunohistochemical study of the enkephalinergic input to dopaminergic neurons of the substantia nigra in pigeons. |
1995-10-19 |
2023-08-12 |
rat |
| L Medina, K D Anderson, E J Karle, A Reine. An ultrastructural double-label immunohistochemical study of the enkephalinergic input to dopaminergic neurons of the substantia nigra in pigeons. The Journal of comparative neurology. vol 357. issue 3. 1995-10-19. PMID:7673476. |
enk+ terminals in the substantia nigra were labeled with antileucine-enkephalin antiserum by using peroxidase-antiperoxidase methods, and dopaminergic neurons were labeled with anti-tyrosine hydroxylase antiserum by using silver-intensified immunogold methods. |
1995-10-19 |
2023-08-12 |
rat |
| L Medina, K D Anderson, E J Karle, A Reine. An ultrastructural double-label immunohistochemical study of the enkephalinergic input to dopaminergic neurons of the substantia nigra in pigeons. The Journal of comparative neurology. vol 357. issue 3. 1995-10-19. PMID:7673476. |
the results indicate that enk+ striatonigral neurons in birds may directly influence both dopaminergic and nondopaminergic neurons of the substantia nigra. |
1995-10-19 |
2023-08-12 |
rat |
| J Röper, F M Ashcrof. Metabolic inhibition and low internal ATP activate K-ATP channels in rat dopaminergic substantia nigra neurones. Pflugers Archiv : European journal of physiology. vol 430. issue 1. 1995-10-10. PMID:7667078. |
metabolic inhibition and low internal atp activate k-atp channels in rat dopaminergic substantia nigra neurones. |
1995-10-10 |
2023-08-12 |
rat |
| J A Richter, M G Brenneman, S R Dlouhy, B Ghett. Dopaminergic parameters in the striatum and substantia nigra of seven strains of mice: higher density in striatum of CAST compared to BALB mice. Neurochemical research. vol 20. issue 4. 1995-09-27. PMID:7651576. |
dopaminergic parameters in the striatum and substantia nigra of seven strains of mice: higher density in striatum of cast compared to balb mice. |
1995-09-27 |
2023-08-12 |
mouse |