| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T A Jenkins, A M Allen, S Y Chai, D P MacGregor, G Paxinos, F A Mendelsoh. Interactions of angiotensin II with central dopamine. Advances in experimental medicine and biology. vol 396. 1996-12-03. PMID:8726689. |
it also extends to the nigrostriatal dopaminergic system which bear at1 receptors, both on their cell bodies in the substantia nigra presynaptically, and on their terminals in the striatum, where ang ii can markedly potentiate da release. |
1996-12-03 |
2023-08-12 |
Not clear |
| P Anglade, A Mouatt-Prigent, Y Agid, E Hirsc. Synaptic plasticity in the caudate nucleus of patients with Parkinson's disease. Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration. vol 5. issue 2. 1996-12-03. PMID:8819132. |
the loss of dopaminergic neurons from the substantia nigra in parkinson's disease (pd) may provoke a reorganization of cellular interactions in the nigrostriatal pathway. |
1996-12-03 |
2023-08-12 |
human |
| D G Schaar, M R Varia, S Elkabes, L Ramakrishnan, C F Dreyfus, I B Blac. The identification of a novel cDNA preferentially expressed in the olfactory-limbic system of the adult rat. Brain research. vol 721. issue 1-2. 1996-11-27. PMID:8793103. |
our previous studies indicated that local substantia nigra (sn) type 1 astrocytes elaborate an array of trophic molecules which support the survival of sn dopaminergic neurons. |
1996-11-27 |
2023-08-12 |
rat |
| M Garcia-Munoz, D S Segal, P Patino, S J Young, R Kuczenski, P M Grove. Amphetamine-induced changes in nigrostriatal terminal excitability are modified following repeated amphetamine pretreatment. Brain research. vol 720. issue 1-2. 1996-11-25. PMID:8782905. |
either 24 h or 14 days after the last injection, extracellular recordings were obtained from dopaminergic neurons of the substantia nigra, in a blind design in which the experimenter did not know the pretreatment regime. |
1996-11-25 |
2023-08-12 |
rat |
| D J Surmeier, P G Mermelstein, D Goldowit. The weaver mutation of GIRK2 results in a loss of inwardly rectifying K+ current in cerebellar granule cells. Proceedings of the National Academy of Sciences of the United States of America. vol 93. issue 20. 1996-11-25. PMID:8855331. |
the weaver mutation in mice results in a severe ataxia that is attributable to the degeneration of cerebellar granule cells and dopaminergic neurons in the substantia nigra. |
1996-11-25 |
2023-08-12 |
mouse |
| X M Shen, G Dryhurs. Further insights into the influence of L-cysteine on the oxidation chemistry of dopamine: reaction pathways of potential relevance to Parkinson's disease. Chemical research in toxicology. vol 9. issue 4. 1996-11-19. PMID:8831820. |
the initial step in the genesis of neuromelanin, a black polymeric pigment normally found in the cytoplasm of dopaminergic cell bodies in the substantia nigra (sn), is the autoxidation of dopamine (da) to da-o-quinone (1). |
1996-11-19 |
2023-08-12 |
mouse |
| R A Barker, S B Dunnett, A Faissner, J W Fawcet. The time course of loss of dopaminergic neurons and the gliotic reaction surrounding grafts of embryonic mesencephalon to the striatum. Experimental neurology. vol 141. issue 1. 1996-11-12. PMID:8797670. |
however, when examined some weeks after implantation, grafted substantia nigra only contains about 5% of the expected complement of dopaminergic neurons. |
1996-11-12 |
2023-08-12 |
rat |
| O Bandmann, M B Davis, C D Marsden, N W Woo. The human homologue of the weaver mouse gene in familial and sporadic Parkinson's disease. Neuroscience. vol 72. issue 4. 1996-11-01. PMID:8735215. |
the pathological hallmark of parkinson's disease is cell death of dopaminergic neurons in the substantia nigra, resulting in striatal dopaminergic deficit and a clinical syndrome dominated by disorders of movement. |
1996-11-01 |
2023-08-12 |
mouse |
| T Alexi, F Heft. Neurotrophin-4/5 selectively protects nigral calbindin-containing neurons in rats with medial forebrain bundle transections. Neuroscience. vol 72. issue 4. 1996-11-01. PMID:8735219. |
unilateral transections resulted in a partial reduction of the number of dopaminergic neurons as identified by immunocytochemistry for tyrosine hydroxylase to approximately half of the number of neurons present on the intact contralateral substantia nigra. |
1996-11-01 |
2023-08-12 |
rat |
| J L Cornish, M van den Buus. Stimulation of the rat mesolimbic dopaminergic system produces a pressor response which is mediated by dopamine D-1 and D-2 receptor activation and the release of vasopressin. Brain research. vol 701. issue 1-2. 1996-10-25. PMID:8925292. |
the administration of dime-c7 into the region of origin of the nigrostriatal a9 dopaminergic system, the substantia nigra, produced a slight but significant increase in blood pressure with little effect on heart rate. |
1996-10-25 |
2023-08-12 |
rat |
| S Hunot, F Boissière, B Faucheux, B Brugg, A Mouatt-Prigent, Y Agid, E C Hirsc. Nitric oxide synthase and neuronal vulnerability in Parkinson's disease. Neuroscience. vol 72. issue 2. 1996-10-24. PMID:8737406. |
however, it cannot be excluded that the presence of glial cells expressing nitric oxide synthase in the substantia nigra of patients with parkinson's disease represents a consequence of dopaminergic neuronal loss. |
1996-10-24 |
2023-08-12 |
human |
| E Kienzl, L Puchinger, K Jellinger, W Linert, H Stachelberger, R F Jameso. The role of transition metals in the pathogenesis of Parkinson's disease. Journal of the neurological sciences. vol 134 Suppl. 1996-10-24. PMID:8847547. |
the mechanisms that lead to degeneration of melanized dopaminergic neurons in the brain stem, and particularly in the substantia nigra (sn) in patients with parkinson's disease (pd) are still unknown. |
1996-10-24 |
2023-08-12 |
Not clear |
| S Fenu, A Carta, M Morell. Intranigral injections of glutamate antagonists modulate dopamine D1-mediated turning behavior and striatal c-fos expression. Journal of neural transmission. Supplementum. vol 45. 1996-10-23. PMID:8748612. |
the contribution of the substantia nigra (sn) in the positive interaction between dopamine d1 receptor agonists and glutamate antagonists was studied in rats with a unilateral 6-hydroxydopamine (6-ohda) lesion of dopaminergic nigro-striatal pathway. |
1996-10-23 |
2023-08-12 |
rat |
| N A Uranov. [Brain synaptic plasticity in schizophrenia]. Vestnik Rossiiskoi akademii meditsinskikh nauk. issue 4. 1996-10-23. PMID:8754075. |
in some postmortem brain structures of the dopaminergic system: the substantia nigra, ventral tegmentum area, prefrontal cortex (area 10), anterior cingulate cortex (area 24), the head of the caudate nucleus in schizophrenia and age-matched controls without mental disorders. |
1996-10-23 |
2023-08-12 |
Not clear |
| D A McRitchie, C D Hardman, G M Hallida. Cytoarchitectural distribution of calcium binding proteins in midbrain dopaminergic regions of rats and humans. The Journal of comparative neurology. vol 364. issue 1. 1996-10-23. PMID:8789281. |
the results suggest that few dopaminergic neurons receiving striatal input in the substantia nigra contain calcium binding proteins; rather, the nondopaminergic nigral neurons contain parvalbumin. |
1996-10-23 |
2023-08-12 |
human |
| P Hulley, J Hartikka, S Abdel'Al, P Engels, H R Buerki, K H Wiederhold, T Müller, P Kelly, D Lowe, H Lübber. Inhibitors of type IV phosphodiesterases reduce the toxicity of MPTP in substantia nigra neurons in vivo. The European journal of neuroscience. vol 7. issue 12. 1996-10-22. PMID:8845948. |
the neuropathology of parkinson's disease is characterized by the degeneration of dopaminergic neurons in the substantia nigra. |
1996-10-22 |
2023-08-12 |
mouse |
| P Hulley, J Hartikka, S Abdel'Al, P Engels, H R Buerki, K H Wiederhold, T Müller, P Kelly, D Lowe, H Lübber. Inhibitors of type IV phosphodiesterases reduce the toxicity of MPTP in substantia nigra neurons in vivo. The European journal of neuroscience. vol 7. issue 12. 1996-10-22. PMID:8845948. |
thus, protein kinase a regulates the survival and differentiation of dopaminergic substantia nigra neurons in vivo, implicating a therapeutic potential for substances which regulate camp turnover in these neurons. |
1996-10-22 |
2023-08-12 |
mouse |
| K M Kim, Y Nakajima, S Nakajim. G protein-coupled inward rectifier modulated by dopamine agonists in cultured substantia nigra neurons. Neuroscience. vol 69. issue 4. 1996-10-22. PMID:8848103. |
dopamine release from dopaminergic neurons in the substantia nigra plays an important role in regulating their activity. |
1996-10-22 |
2023-08-12 |
Not clear |
| S Patel, J Roberts, J Moorman, C Reavil. Localization of serotonin-4 receptors in the striatonigral pathway in rat brain. Neuroscience. vol 69. issue 4. 1996-10-22. PMID:8848104. |
however, serotonin-4 receptors are not located on dopaminergic neurons, either on their cell bodies in the substantia nigra or terminals in the striatum. |
1996-10-22 |
2023-08-12 |
rat |
| M Yamada, C Bolden-Watson, M A Watson, T Cho, N J Coleman, M Yamada, E Richelso. Regulation of neurotensin receptor mRNA expression by the receptor antagonist SR 48692 in the rat midbrain dopaminergic neurons. Brain research. Molecular brain research. vol 33. issue 2. 1996-10-09. PMID:8750895. |
in this study, we demonstrated that the tyrosine hydroxylase-like immuno-reactive (possibly dopaminergic) neurons express neurotensin receptor mrna in the rat substantia nigra and in the ventral tegmental area. |
1996-10-09 |
2023-08-12 |
rat |