| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J L Venero, M Revuelta, J Cano, A Machad. Time course changes in the dopaminergic nigrostriatal system following transection of the medial forebrain bundle: detection of oxidatively modified proteins in substantia nigra. Journal of neurochemistry. vol 68. issue 6. 1997-06-17. PMID:9166740. |
this effect was correlated with the neurochemical activity of the dopaminergic and serotoninergic systems in the substantia nigra, which suggests a role of dopamine- and serotonin-derived radical oxygen species in the oxidative stress detected in this brain area. |
1997-06-17 |
2023-08-12 |
Not clear |
| J L Venero, M Revuelta, J Cano, A Machad. Time course changes in the dopaminergic nigrostriatal system following transection of the medial forebrain bundle: detection of oxidatively modified proteins in substantia nigra. Journal of neurochemistry. vol 68. issue 6. 1997-06-17. PMID:9166740. |
the course of necrotic cell death in the substantia nigra coincided with the maximal levels of oxidatively modified proteins in the substantia nigra, suggesting a link between oxidative stress and nerve cell death and also coinciding with the neurochemical activity of both dopaminergic and serotoninergic systems. |
1997-06-17 |
2023-08-12 |
Not clear |
| E Bezard, T Boraud, B Bioulac, C E Gros. Presymptomatic revelation of experimental parkinsonism. Neuroreport. vol 8. issue 2. 1997-06-13. PMID:9080424. |
parkinson's disease results from a progressive loss of dopaminergic neurones of the substantia nigra (snc). |
1997-06-13 |
2023-08-12 |
monkey |
| J Pierre, M Mahouche, E I Suderevskaya, J Repérant, R War. Immunocytochemical localization of dopamine and its synthetic enzymes in the central nervous system of the lamprey Lampetra fluviatilis. The Journal of comparative neurology. vol 380. issue 1. 1997-06-06. PMID:9073087. |
the dopaminergic system of the lamprey appears to share many features not only with that of other anamniotes but also with that of amniotes; however, as in teleosts, dopaminergic neurons in the midbrain corresponding to the substantia nigra, the retrorubral area, and the ventral tegmental area of other species do not exist in the lamprey. |
1997-06-06 |
2023-08-12 |
Not clear |
| P Anglade, S Vyas, F Javoy-Agid, M T Herrero, P P Michel, J Marquez, A Mouatt-Prigent, M Ruberg, E C Hirsch, Y Agi. Apoptosis and autophagy in nigral neurons of patients with Parkinson's disease. Histology and histopathology. vol 12. issue 1. 1997-06-03. PMID:9046040. |
parkinson's disease (pd) is a neurodegenerative disorder characterized by progressive cell loss confined mostly to dopaminergic neurons of the substantia nigra. |
1997-06-03 |
2023-08-12 |
Not clear |
| M Trupp, N Belluardo, H Funakoshi, C F Ibáñe. Complementary and overlapping expression of glial cell line-derived neurotrophic factor (GDNF), c-ret proto-oncogene, and GDNF receptor-alpha indicates multiple mechanisms of trophic actions in the adult rat CNS. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 10. 1997-06-02. PMID:9133379. |
glial cell line-derived neurotrophic factor (gdnf), the most potent trophic factor yet described for both dopaminergic neurons of the substantia nigra and spinal motorneurons, has recently been shown to signal through a multireceptor complex composed of a novel glycosylphosphatidylinositol-anchored gdnf receptor-alpha (gdnfr-alpha) and the receptor tyrosine kinase product of the c-ret proto-oncogene (ret). |
1997-06-02 |
2023-08-12 |
rat |
| M Chritin, V Blanchard, R Raisman-Vozari, C Feuerstein, Y Agid, F Javoy-Agid, M Savast. DA uptake sites, D1 and D2 receptors, D2 and preproenkephalin mRNAs and Fos immunoreactivity in rat striatal subregions after partial dopaminergic degeneration. The European journal of neuroscience. vol 8. issue 12. 1997-05-29. PMID:8996800. |
stereotaxic injection of a limited amount of 6-hydroxydopamine in the lateral part of the rat substantia nigra induces a partial degeneration of the nigrostriatal dopaminergic system. |
1997-05-29 |
2023-08-12 |
rat |
| C Adelbrecht, Y Agid, R Raisman-Vozar. Effect of the weaver mutation on the expression of dopamine membrane transporter, tyrosine hydroxylase and vesicular monoamine transporter in dopaminergic neurons of the substantia nigra and the ventral tegmental area. Brain research. Molecular brain research. vol 43. issue 1-2. 1997-05-29. PMID:9037545. |
effect of the weaver mutation on the expression of dopamine membrane transporter, tyrosine hydroxylase and vesicular monoamine transporter in dopaminergic neurons of the substantia nigra and the ventral tegmental area. |
1997-05-29 |
2023-08-12 |
mouse |
| T F Oo, R E Burk. The time course of developmental cell death in phenotypically defined dopaminergic neurons of the substantia nigra. Brain research. Developmental brain research. vol 98. issue 2. 1997-05-27. PMID:9051260. |
the time course of developmental cell death in phenotypically defined dopaminergic neurons of the substantia nigra. |
1997-05-27 |
2023-08-12 |
rat |
| M Yamada, K Groshan, C T Phung, M Yamada, T Hisamitsu, E Richelso. The expression of mRNA for a kappa opioid receptor in the substantia nigra of Parkinson's disease brain. Brain research. Molecular brain research. vol 44. issue 1. 1997-05-22. PMID:9030693. |
kappa opioid receptor mrna was present in melanized (possibly dopaminergic) neurons of the substantia nigra and the nucleus paranigralis. |
1997-05-22 |
2023-08-12 |
human |
| M Yamada, K Groshan, C T Phung, M Yamada, T Hisamitsu, E Richelso. The expression of mRNA for a kappa opioid receptor in the substantia nigra of Parkinson's disease brain. Brain research. Molecular brain research. vol 44. issue 1. 1997-05-22. PMID:9030693. |
from these results we suggest that dopaminergic neurons in the human substantia nigra and the nucleus paranigralis synthesize kappa opioid receptors and express them in their perikarya and their terminal regions. |
1997-05-22 |
2023-08-12 |
human |
| I Aubert, C Brana, C Pellevoisin, B Giros, I Caille, D Carles, C Vital, B Bloc. Molecular anatomy of the development of the human substantia nigra. The Journal of comparative neurology. vol 379. issue 1. 1997-05-22. PMID:9057113. |
dopaminergic (da) neurons of the substantia nigra were detected through th immunoreactivity from week 12. |
1997-05-22 |
2023-08-12 |
human |
| I Aubert, C Brana, C Pellevoisin, B Giros, I Caille, D Carles, C Vital, B Bloc. Molecular anatomy of the development of the human substantia nigra. The Journal of comparative neurology. vol 379. issue 1. 1997-05-22. PMID:9057113. |
our results demonstrate that the developing substantia nigra in human displays early transcriptional and translational activity for the main constituents of dopaminergic transmission from week 12 and receives at this time dopaminoceptive inputs bearing d1 receptors from the striatum. |
1997-05-22 |
2023-08-12 |
human |
| C S Lee, H Sauer, A Bjorklun. Dopaminergic neuronal degeneration and motor impairments following axon terminal lesion by instrastriatal 6-hydroxydopamine in the rat. Neuroscience. vol 72. issue 3. 1997-05-22. PMID:9157311. |
the aim of the present study was to assess the retrograde degenerative changes in the dopaminergic neurons of the substantia nigra and the associated behavioral and neurochemical consequences of intrastriatal injections of 6-hydroxydopamine in young adult rats. |
1997-05-22 |
2023-08-12 |
rat |
| C S Lee, H Sauer, A Bjorklun. Dopaminergic neuronal degeneration and motor impairments following axon terminal lesion by instrastriatal 6-hydroxydopamine in the rat. Neuroscience. vol 72. issue 3. 1997-05-22. PMID:9157311. |
the results show that striatal 6-hydroxydopamine lesions produce dose-dependent decreases in striatal dopamine levels and tyrosine hydroxylase-immunoreactive cell numbers in the ipsilateral substantia nigra, accompanied by a significant long-lasting atrophy of the remaining dopaminergic neurons. |
1997-05-22 |
2023-08-12 |
rat |
| C S Lee, H Sauer, A Bjorklun. Dopaminergic neuronal degeneration and motor impairments following axon terminal lesion by instrastriatal 6-hydroxydopamine in the rat. Neuroscience. vol 72. issue 3. 1997-05-22. PMID:9157311. |
the behavioral, cellular, and neurochemical effects of the nerve terminal lesion thus bear some resemblance to the early stages of parkinson's disease, where the severity of motor impairment is correlated with the loss of dopamine in the striatum and dopaminergic neuronal loss in the substantia nigra. |
1997-05-22 |
2023-08-12 |
rat |
| D A McRitchie, H R Cartwright, G M Hallida. Specific A10 dopaminergic nuclei in the midbrain degenerate in Parkinson's disease. Experimental neurology. vol 144. issue 1. 1997-05-20. PMID:9126172. |
using unbiased quantitative techniques, we evaluated the effect of parkinson's disease on the regional size and the number of tyrosine hydroxylase-producing neurons and all neurons in the midbrain a8 and a10 dopaminergic cell groups located adjacent to the substantia nigra. |
1997-05-20 |
2023-08-12 |
Not clear |
| A S Hazell, Y Itzhak, H Liu, M D Norenber. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) decreases glutamate uptake in cultured astrocytes. Journal of neurochemistry. vol 68. issue 5. 1997-05-15. PMID:9109551. |
the deleterious effect of the parkinsonian neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) on dopaminergic neurons of the substantia nigra is well established. |
1997-05-15 |
2023-08-12 |
Not clear |
| R P Gaykema, L Zaborszk. Parvalbumin-containing neurons in the basal forebrain receive direct input from the substantia nigra-ventral tegmental area. Brain research. vol 747. issue 1. 1997-05-14. PMID:9042545. |
by means of anterograde tracing of phaseolus vulgaris-leucoagglutinin (pha-l) it was determined if parvalbumin-immunoreactive neurons in the basal forebrain receive a direct synaptic input from the a9-a10 dopaminergic nuclei of the substantia nigra and ventral tegmental area. |
1997-05-14 |
2023-08-12 |
Not clear |
| E Bertrand, W Lechowicz, G M Szpak, J Dymeck. [Morphometric assessment of lesions in the dopaminergic nigrostriatal system in Parkinson disease]. Neurologia i neurochirurgia polska. vol 30. issue 5. 1997-05-12. PMID:9148173. |
a morphometric quantitative study of depletion of pigmented dopaminergic cells of substantia nigra was performed in six long-term cases of the disease. |
1997-05-12 |
2023-08-12 |
human |