| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| F M Göldner, K T Dineley, J W Patric. Immunohistochemical localization of the nicotinic acetylcholine receptor subunit alpha6 to dopaminergic neurons in the substantia nigra and ventral tegmental area. Neuroreport. vol 8. issue 12. 1997-10-23. PMID:9295110. |
immunohistochemical localization of the nicotinic acetylcholine receptor subunit alpha6 to dopaminergic neurons in the substantia nigra and ventral tegmental area. |
1997-10-23 |
2023-08-12 |
rat |
| F M Göldner, K T Dineley, J W Patric. Immunohistochemical localization of the nicotinic acetylcholine receptor subunit alpha6 to dopaminergic neurons in the substantia nigra and ventral tegmental area. Neuroreport. vol 8. issue 12. 1997-10-23. PMID:9295110. |
alpha6 immunoreactivity was found to be present in the substantia nigra, the ventral tegmental area, the locus coeruleus and the medial habenula, and double-labeling for tyrosine hydroxylase demonstrated that the alpha6 protein is present on dopaminergic neurons of the midbrain. |
1997-10-23 |
2023-08-12 |
rat |
| P Anglade, S Vyas, E C Hirsch, Y Agi. Apoptosis in dopaminergic neurons of the human substantia nigra during normal aging. Histology and histopathology. vol 12. issue 3. 1997-10-22. PMID:9225140. |
apoptosis in dopaminergic neurons of the human substantia nigra during normal aging. |
1997-10-22 |
2023-08-12 |
human |
| Y Li, P Maher, D Schuber. A role for 12-lipoxygenase in nerve cell death caused by glutathione depletion. Neuron. vol 19. issue 2. 1997-10-16. PMID:9292733. |
an early and highly specific decrease in glutathione (gsh) in the substantia nigra is associated with parkinson's disease, and low levels of gsh lead to the degeneration of cultured dopaminergic neurons. |
1997-10-16 |
2023-08-12 |
Not clear |
| E A Kordysh, Y Herishanu, J R Goldsmit. Chemical exposures and Parkinson's disease in residents of three Negev kibbutzim. Environmental research. vol 73. issue 1-2. 1997-10-15. PMID:9311542. |
literature data on pd pathogenesis have been compared with common pathogenetic pathways to xenobiotics effects; the following neurotoxic mechanisms, besides individual sensitivity, have been suggested: (1) impairment of the protective role of the substantia nigra against toxicants by binding of chemicals to melanin; (2) oxidative stress induction, including glutathione reduction, impaired calcium metabolism, and alteration of cytochrome p-450 activity; (3) blockade of iron chelators because of structural similarities to them or their precursors; (4) mediation of the production of endogenous dopaminergic neurotoxins, such as trichloroharmanes or isoquinolines; (5) blockade of dopamine receptors because of their resemblance to chemicals with affinity to these receptors; (6) stimulation of prostaglandin-h synthase and monooxygenase activity; and (7) stimulation of autoimmune processes and creation of autoimmunity to structures of the dopaminergic system caused by chemical similarity. |
1997-10-15 |
2023-08-12 |
Not clear |
| M M Winnicka, J J Braszk. 6-OHDA lesions to the central amygdala abolish angiotensins facilitation of object recognition in rats. General pharmacology. vol 29. issue 2. 1997-10-02. PMID:9251906. |
we have previously reported that the dopaminergic projection from a10 ventral tegmental neurons and a9 neurons of substantia nigra to the central amygdala (ca) is, in part, responsible for the facilitatory effect of angiotensin ii (aii) and its 3-7 fragment [aii(3-7)] on the retrieval of information in memory that is motivated affectively. |
1997-10-02 |
2023-08-12 |
rat |
| C Henchcliffe, R E Burk. Increased expression of cyclin-dependent kinase 5 in induced apoptotic neuron death in rat substantia nigra. Neuroscience letters. vol 230. issue 1. 1997-09-24. PMID:9259459. |
we reported previously that striatal excitotoxic lesion with quinolinic acid of rat pups during the first 2 weeks of postnatal life results in loss of dopaminergic neurons of the substantia nigra (sn) due to induced apoptosis. |
1997-09-24 |
2023-08-12 |
rat |
| N B Mercuri, A Saiardi, A Bonci, R Picetti, P Calabresi, G Bernardi, E Borrell. Loss of autoreceptor function in dopaminergic neurons from dopamine D2 receptor deficient mice. Neuroscience. vol 79. issue 2. 1997-09-05. PMID:9200717. |
dopaminergic neurons arise from the ventral tegmental area and the substantia nigra. |
1997-09-05 |
2023-08-12 |
mouse |
| S K Mukherjee, L K Klaidman, R Yasharel, J D Adam. Increased brain NAD prevents neuronal apoptosis in vivo. European journal of pharmacology. vol 330. issue 1. 1997-09-02. PMID:9228411. |
mptp selectively damages dopaminergic neurons in the substantia nigra of the midbrain. |
1997-09-02 |
2023-08-12 |
Not clear |
| P Polla. [Mechanisms and treatments of Parkinson disease]. La Revue du praticien. vol 47. issue 10. 1997-08-05. PMID:9208669. |
the loss of dopaminergic melanized neurons of the substantia nigra is the main lesion of parkinson's disease. |
1997-08-05 |
2023-08-12 |
Not clear |
| R L Watt. The role of dopamine agonists in early Parkinson's disease. Neurology. vol 49. issue 1 Suppl 1. 1997-08-04. PMID:9222273. |
because they act on postsynaptic dopamine receptors of the striatum, dopamine agonists act independent of the synthetic dopaminergic enzyme system and are not dependent on degenerating presynaptic neurons in the substantia nigra. |
1997-08-04 |
2023-08-12 |
Not clear |
| H Allain, D Bentué-Ferre. [Parkinson disease: interrogations and solutions]. Presse medicale (Paris, France : 1983). vol 26. issue 19. 1997-08-04. PMID:9232065. |
a neurodegenerative disease: idiopathic parkinson's disease is initially due to a selective and specific destruction of the pars compacta dopaminergic neurons in substantia nigra. |
1997-08-04 |
2023-08-12 |
Not clear |
| K R Oliver, P Brennan, J K Fazakerle. Specific infection and destruction of dopaminergic neurons in the substantia nigra by Theiler's virus. Journal of virology. vol 71. issue 8. 1997-07-31. PMID:9223513. |
specific infection and destruction of dopaminergic neurons in the substantia nigra by theiler's virus. |
1997-07-31 |
2023-08-12 |
mouse |
| J Balthazart, P Absi. Identification of catecholaminergic inputs to and outputs from aromatase-containing brain areas of the Japanese quail by tract tracing combined with tyrosine hydroxylase immunocytochemistry. The Journal of comparative neurology. vol 382. issue 3. 1997-07-30. PMID:9183702. |
in these last two regions, many retrogradely labeled cells were located in dopaminergic areas such as the retroruberal field (rrf), substantia nigra (sn), and area ventralis of tsai (avt) but also in noradrenergic cell groups such as the locus ceruleus and subceruleus. |
1997-07-30 |
2023-08-12 |
Not clear |
| E Nalivaiko, J C Michaud, P Soubrié, G Le Fur, P Felt. Tachykinin neurokinin-1 and neurokinin-3 receptor-mediated responses in guinea-pig substantia nigra: an in vitro electrophysiological study. Neuroscience. vol 78. issue 3. 1997-07-21. PMID:9153655. |
we conclude that, in the guinea-pig substantia nigra, tachykinins evoke excitatory responses in both dopaminergic and non-dopaminergic neurons; however, the sensitivity to tachykinin agonists (neurokinin-1 versus neurokinin-3) depends on both neuronal type and localization. |
1997-07-21 |
2023-08-12 |
Not clear |
| N S Haque, C J LeBlanc, O Isacso. Differential dissection of the rat E16 ventral mesencephalon and survival and reinnervation of the 6-OHDA-lesioned striatum by a subset of aldehyde dehydrogenase-positive TH neurons. Cell transplantation. vol 6. issue 3. 1997-07-21. PMID:9171157. |
the retinoic acid-generating enzyme, aldehyde dehydrogenase (ahd), is expressed in a subpopulation of dopaminergic neurons found in the substantia nigra. |
1997-07-21 |
2023-08-12 |
rat |
| M D Lindner, M A Plone, J M Francis, T J Blaney, J D Salamone, D F Emeric. Rats with partial striatal dopamine depletions exhibit robust and long-lasting behavioral deficits in a simple fixed-ratio bar-pressing task. Behavioural brain research. vol 86. issue 1. 1997-07-15. PMID:9105579. |
it is widely accepted that enduring parkinsonian symptoms are only evident if there are few remaining dopaminergic neurons in the substantia nigra and dopamine levels in the basal ganglia are very low [26,41]. |
1997-07-15 |
2023-08-12 |
rat |
| A Gasbarri, A Sulli, M G Packar. The dopaminergic mesencephalic projections to the hippocampal formation in the rat. Progress in neuro-psychopharmacology & biological psychiatry. vol 21. issue 1. 1997-06-27. PMID:9075256. |
the dopaminergic mesencephalic neurons projecting to the hippocampal formation are distributed in three cell groups: a8 region in the retrorubral field, a9 region in the substantia nigra and a10 region in the ventral tegmental area. |
1997-06-27 |
2023-08-12 |
rat |
| N A Pochon, A Menoud, J L Tseng, A D Zurn, P Aebische. Neuronal GDNF expression in the adult rat nervous system identified by in situ hybridization. The European journal of neuroscience. vol 9. issue 3. 1997-06-27. PMID:9104588. |
double labelling of the substantia nigra using tyrosine hydroxylase immunohistochemistry, associated with gdnf in situ hybridization, show that the majority of dopaminergic neurons express gdnf. |
1997-06-27 |
2023-08-12 |
rat |
| J L Venero, M Revuelta, J Cano, A Machad. Time course changes in the dopaminergic nigrostriatal system following transection of the medial forebrain bundle: detection of oxidatively modified proteins in substantia nigra. Journal of neurochemistry. vol 68. issue 6. 1997-06-17. PMID:9166740. |
time course changes in the dopaminergic nigrostriatal system following transection of the medial forebrain bundle: detection of oxidatively modified proteins in substantia nigra. |
1997-06-17 |
2023-08-12 |
Not clear |