| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tiziana M Florio, Giuseppina Confalone, Alessandro Sciarra, Antonello Sotgiu, Marcello Alecc. Switching ability of over trained movements in a Parkinson's disease rat model. Behavioural brain research. vol 250. 2013-10-25. PMID:23707247. |
we studied the effect of a selective loss of dopaminergic terminals within the striatum and the execution of a well-learned set-shifting task as revealed using tyrosine hydroxylase immunoreactivity and magnetic resonance imaging in the rat. |
2013-10-25 |
2023-08-12 |
rat |
| Omar El Hiba, Halima Gamrani, Hicham Chatoui, Samir Ahbouch. Loss of tyrosine hydroxylase expression within the nigro-striato-cortical pathways in the cirrhotic rat: the possible restorative effect of the neurosteroid dehydroepiandrosterone sulfate. Acta histochemica. vol 115. issue 6. 2013-10-18. PMID:23453752. |
three daily injections of 5mg/kg of dheas to bdl rats significantly normalized th expression decrease in both snc and vta as well as dopaminergic projections to the striatum and the cortex of bdl rats. |
2013-10-18 |
2023-08-12 |
rat |
| Yuval Aluf, Jacob Vaya, Soliman Khatib, Yelena Loboda, John P M Finber. Selective inhibition of monoamine oxidase A or B reduces striatal oxidative stress in rats with partial depletion of the nigro-striatal dopaminergic pathway. Neuropharmacology. vol 65. 2013-10-17. PMID:22982254. |
partial lesion (50%) of the nigro-striatal dopaminergic pathway induces compensatory increase in dopamine release from the remaining neurons and increased extracellular oxidative stress (os(-ec)) in the striatum. |
2013-10-17 |
2023-08-12 |
rat |
| Paul R A Stokes, Paul Shotbolt, Mitul A Mehta, Eric Turkheimer, Aaf Benecke, Caroline Copeland, Federico E Turkheimer, Anne R Lingford-Hughes, Oliver D Howe. Nature or nurture? Determining the heritability of human striatal dopamine function: an [18F]-DOPA PET study. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 3. 2013-10-17. PMID:23093224. |
these findings underline the importance of individual-specific environmental factors for striatal dopaminergic function, particularly in the limbic striatum, with implications for understanding neuropsychiatric disorders such as schizophrenia and addictions. |
2013-10-17 |
2023-08-12 |
human |
| Georgia Rentesi, Katerina Antoniou, Marios Marselos, Marika Syrrou, Zeta Papadopoulou-Daifoti, Maria Konstand. Early maternal deprivation-induced modifications in the neurobiological, neurochemical and behavioral profile of adult rats. Behavioural brain research. vol 244. 2013-09-30. PMID:23395600. |
md rats displayed elevated dopaminergic and serotonergic function in the amygdala and prefrontal cortex, whereas in the striatum only the dopaminergic activity was also increased. |
2013-09-30 |
2023-08-12 |
rat |
| Maria Aguirregomozcorta, Maria Stamelou, Angelo Antonini, Petra Schwingenschuh, Liz Prvulovich, Mark J Edwards, John C Dickson, Kailash P Bhati. Patients with rest-tremor and scans with ipsilateral dopaminergic deficit. Journal of neurology. vol 260. issue 4. 2013-09-26. PMID:23196338. |
however, tremor-dominant parkinson's disease patients may have significantly lower uptake in the striatum ipsilateral to the rest-tremor compared to akinetic-rigid pd patients, implying a possible role of an ipsilateral deficit in the generation of rest-tremor.we report here three patients with rest-tremor and the unexpected finding of an ipsilateral presynaptic dopaminergic deficit with normal uptake contralateral to the rest-tremor in dopamine transporter imaging. |
2013-09-26 |
2023-08-12 |
Not clear |
| V P Chou, T R Holman, A B Manning-Bo. Differential contribution of lipoxygenase isozymes to nigrostriatal vulnerability. Neuroscience. vol 228. 2013-09-23. PMID:23079635. |
taken together, these data provide the first evidence that: (i) lox isozymes are involved in the maintenance of normal dopaminergic function in the striatum and (ii) the 5- and 12/15-lox isozymes contribute differentially to striatal vulnerability in response to neurotoxicant challenge. |
2013-09-23 |
2023-08-12 |
mouse |
| W Tripanichkul, E-O Jaroensuppaperc. Ameliorating effects of curcumin on 6-OHDA-induced dopaminergic denervation, glial response, and SOD1 reduction in the striatum of hemiparkinsonian mice. European review for medical and pharmacological sciences. vol 17. issue 10. 2013-09-04. PMID:23740450. |
ameliorating effects of curcumin on 6-ohda-induced dopaminergic denervation, glial response, and sod1 reduction in the striatum of hemiparkinsonian mice. |
2013-09-04 |
2023-08-12 |
mouse |
| Maria Xilouri, Oeystein Roed Brekk, Natalie Landeck, Pothitos M Pitychoutis, Themistoklis Papasilekas, Zoi Papadopoulou-Daifoti, Deniz Kirik, Leonidas Stefani. Boosting chaperone-mediated autophagy in vivo mitigates α-synuclein-induced neurodegeneration. Brain : a journal of neurology. vol 136. issue Pt 7. 2013-08-29. PMID:23757764. |
overexpression of the lysosomal receptor through the nigral injection of recombinant adeno-associated virus vectors effectively ameliorated α-synuclein-induced dopaminergic neurodegeneration by increasing the survival of neurons located in the substantia nigra as well as the axon terminals located in the striatum, which was associated with a reduction in total α-synuclein levels and related aberrant species. |
2013-08-29 |
2023-08-12 |
human |
| Changlei Xu, Junpeng Zhao, Yujun Liu, Xianzhi Zeng, Yan Jia, Ying Wang, Xiaohua Jiang, Qunyuan X. Dopaminergic axons preferentially innervate dendritic spines with hyperactive glutamatergic synapses in the rat striatum. Brain research. vol 1486. 2013-08-23. PMID:23010310. |
dopaminergic axons preferentially innervate dendritic spines with hyperactive glutamatergic synapses in the rat striatum. |
2013-08-23 |
2023-08-12 |
rat |
| Changlei Xu, Junpeng Zhao, Yujun Liu, Xianzhi Zeng, Yan Jia, Ying Wang, Xiaohua Jiang, Qunyuan X. Dopaminergic axons preferentially innervate dendritic spines with hyperactive glutamatergic synapses in the rat striatum. Brain research. vol 1486. 2013-08-23. PMID:23010310. |
these results demonstrated that dopaminergic axons were biased to a target and preferred to innervate dendritic spines with hyperactive and high-efficacy glutamatergic synapses in the striatum. |
2013-08-23 |
2023-08-12 |
rat |
| Ranier Gutierrez, Mary Kay Lobo, Feng Zhang, Luis de Lece. Neural integration of reward, arousal, and feeding: recruitment of VTA, lateral hypothalamus, and ventral striatal neurons. IUBMB life. vol 63. issue 10. 2013-08-16. PMID:21901814. |
here, we briefly review the causal effect of activity of six genetically defined neural circuits on behavior, including the dopaminergic neurons da in the ventral tegmental area (vta); the two main populations of medium-sized spiny neurons (d1- and d2-positive) in the striatum; the giant cholinergic interneurons in the ventral striatum; and the hypocretin- and mch- expressing neurons in the lateral hypothalamus. |
2013-08-16 |
2023-08-12 |
Not clear |
| Giuseppe Gangarossa, Julie Perroy, Emmanuel Valjen. Combinatorial topography and cell-type specific regulation of the ERK pathway by dopaminergic agonists in the mouse striatum. Brain structure & function. vol 218. issue 2. 2013-08-16. PMID:22453353. |
combinatorial topography and cell-type specific regulation of the erk pathway by dopaminergic agonists in the mouse striatum. |
2013-08-16 |
2023-08-12 |
mouse |
| Polina Petkova-Kirova, Maria Grazia Giovannini, Reni Kalfin, Angelina Rakovsk. Modulation of acetylcholine release by cholecystokinin in striatum: receptor specificity; role of dopaminergic neuronal activity. Brain research bulletin. vol 89. issue 5-6. 2013-08-16. PMID:22981453. |
modulation of acetylcholine release by cholecystokinin in striatum: receptor specificity; role of dopaminergic neuronal activity. |
2013-08-16 |
2023-08-12 |
rat |
| Polina Petkova-Kirova, Maria Grazia Giovannini, Reni Kalfin, Angelina Rakovsk. Modulation of acetylcholine release by cholecystokinin in striatum: receptor specificity; role of dopaminergic neuronal activity. Brain research bulletin. vol 89. issue 5-6. 2013-08-16. PMID:22981453. |
the presented results indicate that (i) cck-8 is capable of increasing ach elicited by field electrical stimulation in striatum; (ii) cck-8 is more effective in its ach-stimulating effect when dopaminergic activity in striatum is blocked i.e. |
2013-08-16 |
2023-08-12 |
rat |
| A Dhanushkodi, E O Akano, E E Roguski, Y Xue, S K Rao, S G Matta, T S Rex, M P McDonal. A single intramuscular injection of rAAV-mediated mutant erythropoietin protects against MPTP-induced parkinsonism. Genes, brain, and behavior. vol 12. issue 2. 2013-08-09. PMID:23190369. |
analysis of th-positive fibers in the striatum showed normalized density in mptp-lesioned mice pretreated with raav.epos71e, suggesting that enhanced sprouting induced by epos71e may have been responsible for normal behavior and dopaminergic tone in these mice. |
2013-08-09 |
2023-08-12 |
mouse |
| John P M Finber. Pharmacology of Rasagiline, a New MAO-B Inhibitor Drug for the Treatment of Parkinson's Disease with Neuroprotective Potential. Rambam Maimonides medical journal. vol 1. issue 1. 2013-08-05. PMID:23908775. |
although the exact distribution of mao isoforms in different neurons and tissues is not known, dopamine behaves largely as a mao-a substrate in vivo, but following loss of dopaminergic axonal varicosities from the striatum, metabolism by glial mao-b becomes increasingly important. |
2013-08-05 |
2023-08-12 |
human |
| Trent U Steidinger, Sunny R Slone, Huiping Ding, David G Standaert, Talene A Yacoubia. Angiogenin in Parkinson disease models: role of Akt phosphorylation and evaluation of AAV-mediated angiogenin expression in MPTP treated mice. PloS one. vol 8. issue 2. 2013-07-29. PMID:23409128. |
we found that angiogenin overexpression using this approach does not reduce the mptp-induced degeneration of dopaminergic cells in the substantia nigra, nor limit the depletion of dopamine and its metabolites in the striatum. |
2013-07-29 |
2023-08-12 |
mouse |
| Y Zhao, J Xiao, S Gong, J A Clara, M S Ledou. Neural expression of the transcription factor THAP1 during development in rat. Neuroscience. vol 231. 2013-07-25. PMID:23219941. |
in addition to purkinje cells in the cerebellum, thap1-ir was also localized to pyramidal neurons in the cerebral cortex, relay neurons in the thalamus, medium spiny and cholinergic neurons in the striatum, dopaminergic neurons in the substantia nigra, and pyramidal and interneurons in the hippocampus. |
2013-07-25 |
2023-08-12 |
rat |
| Marian E Berryhill, Martin Wiener, Jaclyn A Stephens, Falk W Lohoff, H Branch Coslet. COMT and ANKK1-Taq-Ia genetic polymorphisms influence visual working memory. PloS one. vol 8. issue 1. 2013-07-17. PMID:23383291. |
these findings link wm performance with slower dopaminergic metabolism in the prefrontal cortex as well as a greater density of dopamine receptors in the striatum. |
2013-07-17 |
2023-08-12 |
human |