| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gabriela Oana Bodea, Jan-Hendrik Spille, Philipp Abe, Aycan Senturk Andersson, Amparo Acker-Palmer, Ralf Stumm, Ulrich Kubitscheck, Sandra Blaes. Reelin and CXCL12 regulate distinct migratory behaviors during the development of the dopaminergic system. Development (Cambridge, England). vol 141. issue 3. 2014-03-20. PMID:24449842. |
the proper functioning of the dopaminergic system requires the coordinated formation of projections extending from dopaminergic neurons in the substantia nigra (sn), ventral tegmental area (vta) and retrorubral field to a wide array of forebrain targets including the striatum, nucleus accumbens and prefrontal cortex. |
2014-03-20 |
2023-08-12 |
mouse |
| Rumana Chowdhury, Christian Lambert, Raymond J Dolan, Emrah Düze. Parcellation of the human substantia nigra based on anatomical connectivity to the striatum. NeuroImage. vol 81. 2014-03-17. PMID:23684858. |
substantia nigra/ventral tegmental area (sn/vta) subregions, defined by dopaminergic projections to the striatum, are differentially affected by health (e.g. |
2014-03-17 |
2023-08-12 |
human |
| N Emmanuel Díaz-Martínez, Elisa Tamariz, N Fabián Díaz, Claudia M García-Peña, Alfredo Varela-Echavarría, Iván Velasc. Recovery from experimental parkinsonism by semaphorin-guided axonal growth of grafted dopamine neurons. Molecular therapy : the journal of the American Society of Gene Therapy. vol 21. issue 8. 2014-03-06. PMID:23732989. |
one strategy to promote axonal growth of dopaminergic neurons from the substantia nigra (sn) to the striatum is degradation of inhibitory components such as chondroitin sulphate proteoglycans (cspg). |
2014-03-06 |
2023-08-12 |
rat |
| N Emmanuel Díaz-Martínez, Elisa Tamariz, N Fabián Díaz, Claudia M García-Peña, Alfredo Varela-Echavarría, Iván Velasc. Recovery from experimental parkinsonism by semaphorin-guided axonal growth of grafted dopamine neurons. Molecular therapy : the journal of the American Society of Gene Therapy. vol 21. issue 8. 2014-03-06. PMID:23732989. |
we asked whether intranigral transplantation of da neurons, combined with either degradation of cspg or with grafts of semaphorin 3-expressing cells, towards the striatum, is effective in establishing a new nigrostriatal dopaminergic pathway in rats with unilateral depletion of da neurons. |
2014-03-06 |
2023-08-12 |
rat |
| Akie Tanabe, Yukio Yamamura, Jiro Kasahara, Ryoma Morigaki, Ryuji Kaji, Satoshi Got. A novel tyrosine kinase inhibitor AMN107 (nilotinib) normalizes striatal motor behaviors in a mouse model of Parkinson's disease. Frontiers in cellular neuroscience. vol 8. 2014-03-06. PMID:24600352. |
c-abelson tyrosine kinase (c-abl) phosphorylates cyclin-dependent kinase 5 (cdk5) at tyr15 to increase the activity of cdk5, which reduces the efficacy of dopaminergic signaling by phosphorylating darpp-32 at thr75 in the striatum. |
2014-03-06 |
2023-08-12 |
mouse |
| Jessica Deslauriers, Annie Larouche, Philippe Sarret, Sylvain Grigno. Combination of prenatal immune challenge and restraint stress affects prepulse inhibition and dopaminergic/GABAergic markers. Progress in neuro-psychopharmacology & biological psychiatry. vol 45. 2014-02-26. PMID:23697796. |
ppi deficits were accompanied by dopaminergic and gabaergic abnormalities in the prefrontal cortex and striatum. |
2014-02-26 |
2023-08-12 |
mouse |
| Chia-Hsin Liao, Shin-Yuan Chen, Jon-Son Kuo, Cheng-Yoong Pan. Reduction of motor disorder in 6-OHDA-induced severe parkinsonism rats by post treatment with granulocyte-colony stimulating factor. The Chinese journal of physiology. vol 56. issue 3. 2014-02-25. PMID:23656216. |
rats were killed on the 28th day and survival dopaminergic neurons in the substantia nigra, dopaminergic axons and dopaminergic receptor 2 in the striatum were examined. |
2014-02-25 |
2023-08-12 |
mouse |
| Chia-Hsin Liao, Shin-Yuan Chen, Jon-Son Kuo, Cheng-Yoong Pan. Reduction of motor disorder in 6-OHDA-induced severe parkinsonism rats by post treatment with granulocyte-colony stimulating factor. The Chinese journal of physiology. vol 56. issue 3. 2014-02-25. PMID:23656216. |
we, for the first time, demonstrated that post treatment with g-csf reduced abnormal rotational behavior and increased the lesion to non-lesion ratio of dopaminergic fibers in the striatum, but the treatment promoted neither the increase in survival dopaminergic neurons nor the increase in dopaminergic receptor 2 expression. |
2014-02-25 |
2023-08-12 |
mouse |
| Chia-Hsin Liao, Shin-Yuan Chen, Jon-Son Kuo, Cheng-Yoong Pan. Reduction of motor disorder in 6-OHDA-induced severe parkinsonism rats by post treatment with granulocyte-colony stimulating factor. The Chinese journal of physiology. vol 56. issue 3. 2014-02-25. PMID:23656216. |
we conclude that post treatment with g-csf can reduce the abnormal rotational behavior of severe pd rats primarily through relative increases in dopaminergic fibers of the lesion side in the striatum. |
2014-02-25 |
2023-08-12 |
mouse |
| Y Qian, M Chen, H Forssberg, R Diaz Heijt. Genetic variation in dopamine-related gene expression influences motor skill learning in mice. Genes, brain, and behavior. vol 12. issue 6. 2014-02-25. PMID:23819855. |
gene expression analysis of midbrain, frontal cortex and striatum showed significant differences in the expression of presynaptic and postsynaptic dopaminergic (daergic) markers (e.g. |
2014-02-25 |
2023-08-12 |
mouse |
| Marcio Lazzarini, Sabine Martin, Mišo Mitkovski, Rita Raisman Vozari, Walter Stühmer, Elaine Del Be. Doxycycline restrains glia and confers neuroprotection in a 6-OHDA Parkinson model. Glia. vol 61. issue 7. 2014-02-10. PMID:23595698. |
in the 6-ohda mouse model of parkinson's disease, doxycycline administered at a dose that both induces/represses conditional transgene expression in the tetracycline system, mitigates the loss of dopaminergic neurons in the substantia nigra compacta and nerve terminals in the striatum. |
2014-02-10 |
2023-08-12 |
mouse |
| Matthew J Robson, Michael J Seminerio, Christopher R McCurdy, Andrew Coop, Rae R Matsumot. σ Receptor antagonist attenuation of methamphetamine-induced neurotoxicity is correlated to body temperature modulation. Pharmacological reports : PR. vol 65. issue 2. 2014-02-07. PMID:23744418. |
methamphetamine (meth) causes hyperthermia and dopaminergic neurotoxicity in the rodent striatum. |
2014-02-07 |
2023-08-12 |
mouse |
| Chuan-Ching Lai, Li-Jen Lee, Hsiang-Shu Yi. Combinational effects of ketamine and amphetamine on behaviors and neurotransmitter systems of mice. Neurotoxicology. vol 37. 2014-02-05. PMID:23660488. |
dopaminergic and gabaergic systems were affected differentially by the drugs in the striatum. |
2014-02-05 |
2023-08-12 |
mouse |
| Liliana R V Castro, Marina Brito, Elvire Guiot, Marina Polito, Christoph W Korn, Denis Hervé, Jean-Antoine Girault, Danièle Paupardin-Tritsch, Pierre Vincen. Striatal neurones have a specific ability to respond to phasic dopamine release. The Journal of physiology. vol 591. issue 13. 2014-01-28. PMID:23551948. |
the prefrontal cortex and striatum both receive dopaminergic inputs and we analysed the dynamics of the camp/pka signal triggered by dopamine d1 receptors in these two brain structures. |
2014-01-28 |
2023-08-12 |
mouse |
| Youyong Tian, Shenggang Sun, Cuiju Tang, Jianing Wang, Xiaowu Chen, Xian Qia. Intrastriatal gene transfer of vascular endothelial growth factor rescues dopaminergic neurons in a rat Parkinson's disease model. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 26. issue 6. 2014-01-23. PMID:17357485. |
to examine the ability of intrastriatal gene transfer of vascular endothelial growth factor 165 mediated by adenoviral vector to rescue dopaminergic neurons in a rat model of parkinson's disease (pd), we constructed recombinant replication-deficient adenoviral vectors carrying the gene of vegf165 (ad-vegf), and injected ad-vegf (or ad-lacz and pbs as controls) into the striatum of rats 7 days after the lesion by 6-hydroxydopamine. |
2014-01-23 |
2023-08-12 |
rat |
| Patricia Gillespie, Julianne Tajuba, Morton Lippmann, Lung-Chi Chen, Bellina Verones. Particulate matter neurotoxicity in culture is size-dependent. Neurotoxicology. vol 36. 2014-01-13. PMID:22057156. |
together, these data suggest that the inverse relationship between size and toxicity reported in cardiopulmonary systems occurs in cultures of isolated dopaminergic neurons and in primary cultures of the rat striatum. |
2014-01-13 |
2023-08-12 |
rat |
| Alexander Koch, Karin Reich, Jan Wielopolski, Marion Clepce, Marie Fischer, Johannes Kornhuber, Norbert Thuerau. Catatonic dilemma in a 33-year-old woman: a discussion. Case reports in psychiatry. vol 2013. 2014-01-13. PMID:24416611. |
the desirable effect of ect in cases of cs might be dopaminergic stimulation in the striatum and decrease of both the dopaminergic activity in the limbic system and the serotonergic activity on 5-ht2 receptors. |
2014-01-13 |
2023-08-12 |
Not clear |
| Fabia Febbraro, Gurdal Sahin, Aina Farran, Sofia Soares, Poul H Jensen, Deniz Kirik, Marina Romero-Ramo. Ser129D mutant alpha-synuclein induces earlier motor dysfunction while S129A results in distinctive pathology in a rat model of Parkinson's disease. Neurobiology of disease. vol 56. 2014-01-10. PMID:23567651. |
this approach was similar in design to previous studies, however our investigation of dopaminergic degeneration also included performing a detailed study of the α-synuclein induced pathology in the striatum and the analysis of motor deficits. |
2014-01-10 |
2023-08-12 |
human |
| Stéphanie Pain, Alice Gochard, Sylvie Bodard, Zuhal Gulhan, Caroline Prunier-Aesch, Sylvie Chalo. Toxicity of MPTP on neurotransmission in three mouse models of Parkinson's disease. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. vol 65. issue 5. 2014-01-07. PMID:23083629. |
results showed that tyrosine hydroxylase activity and dopaminergic transporter density were reduced in striatum and substantia nigra of mice and that this reduction was dependent on the cumulative dose of mptp injected. |
2014-01-07 |
2023-08-12 |
mouse |
| Pablo Pandolfo, Nuno J Machado, Attila Köfalvi, Reinaldo N Takahashi, Rodrigo A Cunh. Caffeine regulates frontocorticostriatal dopamine transporter density and improves attention and cognitive deficits in an animal model of attention deficit hyperactivity disorder. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 23. issue 4. 2014-01-06. PMID:22561003. |
attention deficit hyperactivity disorder (adhd) likely involves dopaminergic dysfunction in the frontal cortex and striatum, resulting in cognitive and motor abnormalities. |
2014-01-06 |
2023-08-12 |
rat |