| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Oytun Erbas, Fatih Oltulu, Dilek Taskira. Suppression of exaggerated neuronal oscillations by oxytocin in a rat model of Parkinson's disease. General physiology and biophysics. vol 32. issue 4. 2014-03-28. PMID:23970035. |
these findings suggest that injury of dopaminergic neurons triggers exaggerated neuronal oscillations in the striatum and oxytocin may have some inhibitory effects on neuronal activity in pd. |
2014-03-28 |
2023-08-12 |
rat |
| Sudhakar Raja Subramaniam, Marie-Francoise Chessele. Mitochondrial dysfunction and oxidative stress in Parkinson's disease. Progress in neurobiology. vol 106-107. 2014-03-27. PMID:23643800. |
parkinson's disease (pd) is a movement disorder that is characterized by the progressive degeneration of dopaminergic neurons in substantia nigra pars compacta resulting in dopamine deficiency in the striatum. |
2014-03-27 |
2023-08-12 |
Not clear |
| Chris Vriend, Pieter Raijmakers, Dick J Veltman, Karin D van Dijk, Ysbrand D van der Werf, Elisabeth M J Foncke, Jan H Smit, Henk W Berendse, Odile A van den Heuve. Depressive symptoms in Parkinson's disease are related to reduced [123I]FP-CIT binding in the caudate nucleus. Journal of neurology, neurosurgery, and psychiatry. vol 85. issue 2. 2014-03-24. PMID:23813742. |
this suggests regional specificity of dopaminergic deficits in the striatum in motor and depressive symptoms in pd. |
2014-03-24 |
2023-08-12 |
Not clear |
| Y Kwak, N I Bohnen, M L T M Müller, P Dayalu, R D Seidle. Striatal denervation pattern predicts levodopa effects on sequence learning in Parkinson's disease. Journal of motor behavior. vol 45. issue 5. 2014-03-24. PMID:23971968. |
dopaminergic medications can interfere with anteroventral striatum function by overdosing this relatively intact structure. |
2014-03-24 |
2023-08-12 |
Not clear |
| Michael Baca, Andrea M Allan, L Donald Partridge, Michael C Wilso. Gene-environment interactions affect long-term depression (LTD) through changes in dopamine receptor affinity in Snap25 deficient mice. Brain research. vol 1532. 2014-03-21. PMID:23939223. |
using a high frequency stimulus electrophysiological paradigm for long-term depression (ltd) induction, we examined the roles of dopaminergic d2 receptors (d2rs) and cannabinoid cb1 receptors (cb1rs), both critical for ltd induction in the striatum. |
2014-03-21 |
2023-08-12 |
mouse |
| Gabriela Oana Bodea, Jan-Hendrik Spille, Philipp Abe, Aycan Senturk Andersson, Amparo Acker-Palmer, Ralf Stumm, Ulrich Kubitscheck, Sandra Blaes. Reelin and CXCL12 regulate distinct migratory behaviors during the development of the dopaminergic system. Development (Cambridge, England). vol 141. issue 3. 2014-03-20. PMID:24449842. |
the proper functioning of the dopaminergic system requires the coordinated formation of projections extending from dopaminergic neurons in the substantia nigra (sn), ventral tegmental area (vta) and retrorubral field to a wide array of forebrain targets including the striatum, nucleus accumbens and prefrontal cortex. |
2014-03-20 |
2023-08-12 |
mouse |
| Rumana Chowdhury, Christian Lambert, Raymond J Dolan, Emrah Düze. Parcellation of the human substantia nigra based on anatomical connectivity to the striatum. NeuroImage. vol 81. 2014-03-17. PMID:23684858. |
substantia nigra/ventral tegmental area (sn/vta) subregions, defined by dopaminergic projections to the striatum, are differentially affected by health (e.g. |
2014-03-17 |
2023-08-12 |
human |
| N Emmanuel Díaz-Martínez, Elisa Tamariz, N Fabián Díaz, Claudia M García-Peña, Alfredo Varela-Echavarría, Iván Velasc. Recovery from experimental parkinsonism by semaphorin-guided axonal growth of grafted dopamine neurons. Molecular therapy : the journal of the American Society of Gene Therapy. vol 21. issue 8. 2014-03-06. PMID:23732989. |
one strategy to promote axonal growth of dopaminergic neurons from the substantia nigra (sn) to the striatum is degradation of inhibitory components such as chondroitin sulphate proteoglycans (cspg). |
2014-03-06 |
2023-08-12 |
rat |
| N Emmanuel Díaz-Martínez, Elisa Tamariz, N Fabián Díaz, Claudia M García-Peña, Alfredo Varela-Echavarría, Iván Velasc. Recovery from experimental parkinsonism by semaphorin-guided axonal growth of grafted dopamine neurons. Molecular therapy : the journal of the American Society of Gene Therapy. vol 21. issue 8. 2014-03-06. PMID:23732989. |
we asked whether intranigral transplantation of da neurons, combined with either degradation of cspg or with grafts of semaphorin 3-expressing cells, towards the striatum, is effective in establishing a new nigrostriatal dopaminergic pathway in rats with unilateral depletion of da neurons. |
2014-03-06 |
2023-08-12 |
rat |
| Akie Tanabe, Yukio Yamamura, Jiro Kasahara, Ryoma Morigaki, Ryuji Kaji, Satoshi Got. A novel tyrosine kinase inhibitor AMN107 (nilotinib) normalizes striatal motor behaviors in a mouse model of Parkinson's disease. Frontiers in cellular neuroscience. vol 8. 2014-03-06. PMID:24600352. |
c-abelson tyrosine kinase (c-abl) phosphorylates cyclin-dependent kinase 5 (cdk5) at tyr15 to increase the activity of cdk5, which reduces the efficacy of dopaminergic signaling by phosphorylating darpp-32 at thr75 in the striatum. |
2014-03-06 |
2023-08-12 |
mouse |
| Jessica Deslauriers, Annie Larouche, Philippe Sarret, Sylvain Grigno. Combination of prenatal immune challenge and restraint stress affects prepulse inhibition and dopaminergic/GABAergic markers. Progress in neuro-psychopharmacology & biological psychiatry. vol 45. 2014-02-26. PMID:23697796. |
ppi deficits were accompanied by dopaminergic and gabaergic abnormalities in the prefrontal cortex and striatum. |
2014-02-26 |
2023-08-12 |
mouse |
| Chia-Hsin Liao, Shin-Yuan Chen, Jon-Son Kuo, Cheng-Yoong Pan. Reduction of motor disorder in 6-OHDA-induced severe parkinsonism rats by post treatment with granulocyte-colony stimulating factor. The Chinese journal of physiology. vol 56. issue 3. 2014-02-25. PMID:23656216. |
rats were killed on the 28th day and survival dopaminergic neurons in the substantia nigra, dopaminergic axons and dopaminergic receptor 2 in the striatum were examined. |
2014-02-25 |
2023-08-12 |
mouse |
| Chia-Hsin Liao, Shin-Yuan Chen, Jon-Son Kuo, Cheng-Yoong Pan. Reduction of motor disorder in 6-OHDA-induced severe parkinsonism rats by post treatment with granulocyte-colony stimulating factor. The Chinese journal of physiology. vol 56. issue 3. 2014-02-25. PMID:23656216. |
we, for the first time, demonstrated that post treatment with g-csf reduced abnormal rotational behavior and increased the lesion to non-lesion ratio of dopaminergic fibers in the striatum, but the treatment promoted neither the increase in survival dopaminergic neurons nor the increase in dopaminergic receptor 2 expression. |
2014-02-25 |
2023-08-12 |
mouse |
| Chia-Hsin Liao, Shin-Yuan Chen, Jon-Son Kuo, Cheng-Yoong Pan. Reduction of motor disorder in 6-OHDA-induced severe parkinsonism rats by post treatment with granulocyte-colony stimulating factor. The Chinese journal of physiology. vol 56. issue 3. 2014-02-25. PMID:23656216. |
we conclude that post treatment with g-csf can reduce the abnormal rotational behavior of severe pd rats primarily through relative increases in dopaminergic fibers of the lesion side in the striatum. |
2014-02-25 |
2023-08-12 |
mouse |
| Y Qian, M Chen, H Forssberg, R Diaz Heijt. Genetic variation in dopamine-related gene expression influences motor skill learning in mice. Genes, brain, and behavior. vol 12. issue 6. 2014-02-25. PMID:23819855. |
gene expression analysis of midbrain, frontal cortex and striatum showed significant differences in the expression of presynaptic and postsynaptic dopaminergic (daergic) markers (e.g. |
2014-02-25 |
2023-08-12 |
mouse |
| Marcio Lazzarini, Sabine Martin, Mišo Mitkovski, Rita Raisman Vozari, Walter Stühmer, Elaine Del Be. Doxycycline restrains glia and confers neuroprotection in a 6-OHDA Parkinson model. Glia. vol 61. issue 7. 2014-02-10. PMID:23595698. |
in the 6-ohda mouse model of parkinson's disease, doxycycline administered at a dose that both induces/represses conditional transgene expression in the tetracycline system, mitigates the loss of dopaminergic neurons in the substantia nigra compacta and nerve terminals in the striatum. |
2014-02-10 |
2023-08-12 |
mouse |
| Matthew J Robson, Michael J Seminerio, Christopher R McCurdy, Andrew Coop, Rae R Matsumot. σ Receptor antagonist attenuation of methamphetamine-induced neurotoxicity is correlated to body temperature modulation. Pharmacological reports : PR. vol 65. issue 2. 2014-02-07. PMID:23744418. |
methamphetamine (meth) causes hyperthermia and dopaminergic neurotoxicity in the rodent striatum. |
2014-02-07 |
2023-08-12 |
mouse |
| Chuan-Ching Lai, Li-Jen Lee, Hsiang-Shu Yi. Combinational effects of ketamine and amphetamine on behaviors and neurotransmitter systems of mice. Neurotoxicology. vol 37. 2014-02-05. PMID:23660488. |
dopaminergic and gabaergic systems were affected differentially by the drugs in the striatum. |
2014-02-05 |
2023-08-12 |
mouse |
| Liliana R V Castro, Marina Brito, Elvire Guiot, Marina Polito, Christoph W Korn, Denis Hervé, Jean-Antoine Girault, Danièle Paupardin-Tritsch, Pierre Vincen. Striatal neurones have a specific ability to respond to phasic dopamine release. The Journal of physiology. vol 591. issue 13. 2014-01-28. PMID:23551948. |
the prefrontal cortex and striatum both receive dopaminergic inputs and we analysed the dynamics of the camp/pka signal triggered by dopamine d1 receptors in these two brain structures. |
2014-01-28 |
2023-08-12 |
mouse |
| Youyong Tian, Shenggang Sun, Cuiju Tang, Jianing Wang, Xiaowu Chen, Xian Qia. Intrastriatal gene transfer of vascular endothelial growth factor rescues dopaminergic neurons in a rat Parkinson's disease model. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 26. issue 6. 2014-01-23. PMID:17357485. |
to examine the ability of intrastriatal gene transfer of vascular endothelial growth factor 165 mediated by adenoviral vector to rescue dopaminergic neurons in a rat model of parkinson's disease (pd), we constructed recombinant replication-deficient adenoviral vectors carrying the gene of vegf165 (ad-vegf), and injected ad-vegf (or ad-lacz and pbs as controls) into the striatum of rats 7 days after the lesion by 6-hydroxydopamine. |
2014-01-23 |
2023-08-12 |
rat |