| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| David Arkadir, Hagai Bergman, Stanley Fah. Redundant dopaminergic activity may enable compensatory axonal sprouting in Parkinson disease. Neurology. vol 82. issue 12. 2014-05-27. PMID:24663231. |
redundant information encoding results from the similarity of representation of salient and rewarding events by many dopaminergic neurons, from the wide axonal field of a single dopaminergic neuron in the striatum, and from the nonspecific spatial effect of dopamine on striatal neurons (volume conductance). |
2014-05-27 |
2023-08-12 |
human |
| Nicolaas I Bohnen, Klaus Jah. Imaging: What can it tell us about parkinsonian gait? Movement disorders : official journal of the Movement Disorder Society. vol 28. issue 11. 2014-05-19. PMID:24132837. |
dopamine displacement imaging studies have shown evidence for a mesofrontal dopaminergic shift from a depleted striatum in parkinsonian gait. |
2014-05-19 |
2023-08-12 |
Not clear |
| Heidi R Fuller, Maica Llavero Hurtado, Thomas M Wishart, Monte A Gate. The rat striatum responds to nigro-striatal degeneration via the increased expression of proteins associated with growth and regeneration of neuronal circuitry. Proteome science. vol 12. 2014-05-16. PMID:24834013. |
although proteins expressed by the target striatum can positively affect the viability and growth of dopaminergic neurons, very little is known about the molecular response of the striatum as nigro-striatal denervation progresses. |
2014-05-16 |
2023-08-13 |
rat |
| Bernardo Stutz, Fabio Silva Lima da Conceição, Luís Eduardo Santos, Daniel Veloso Cadilhe, Renata L Fleming, Mariana Acquarone, Patrícia F Gardino, Ricardo A de Melo Reis, Phillip W Dickson, Peter R Dunkley, Stevens Rehen, Jean-Christophe Houzel, Fernando G de Mell. Murine dopaminergic Müller cells restore motor function in a model of Parkinson's disease. Journal of neurochemistry. vol 128. issue 6. 2014-05-14. PMID:24117434. |
to address the potential use of dopaminergic müller cells as a source of dopamine in cell therapy procedures, we used a mouse model of parkinson's disease, in which mouse müller cells with the dopaminergic phenotype were transplanted into the striatum of hemi-parkinsonian mice generated by unilateral injection of 6-hydroxydopamine. |
2014-05-14 |
2023-08-12 |
mouse |
| Louise M Collins, Aisling M Gavin, Sinead Walsh, Aideen M Sullivan, Sean L Wyatt, Gerard W O'Keeffe, Yvonne M Nolan, André Toulous. Expression of endogenous Mkp1 in 6-OHDA rat models of Parkinson's disease. SpringerPlus. vol 3. 2014-05-14. PMID:24826373. |
we have previously demonstrated that mitogen-activated protein kinase phosphatase 1, mkp1, is expressed in the developing and rat adult substantia nigra and striatum, where it promotes the growth of nigral dopaminergic neurons. |
2014-05-14 |
2023-08-13 |
rat |
| Jose L Labandeira-Garcia, Jannette Rodriguez-Pallares, Antonio Dominguez-Meijide, Rita Valenzuela, Begoña Villar-Cheda, Ana I Rodríguez-Pere. Dopamine-angiotensin interactions in the basal ganglia and their relevance for Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society. vol 28. issue 10. 2014-05-09. PMID:23925977. |
regulatory interactions between the dopaminergic and renin-angiotensin systems have recently been described in the substantia nigra and striatum. |
2014-05-09 |
2023-08-12 |
Not clear |
| Ahmed E Abdel Monei. The neuroprotective effects of purslane (Portulaca oleracea) on rotenone-induced biochemical changes and apoptosis in brain of rat. CNS & neurological disorders drug targets. vol 12. issue 6. 2014-05-08. PMID:23844694. |
overall, the present study demonstrated the neuroprotective role of purslane in the striatum and proposes its prophylactic potential against developing brain damage and parkinson's disease induction followed by rotenone administration, and that purslane may be considered as a potential neuroprotective agent against environmental factors affecting the function of the dopaminergic system. |
2014-05-08 |
2023-08-12 |
rat |
| Bianca C Wittmann, Geoffrey C Tan, John E Lisman, Raymond J Dolan, Emrah Düze. DAT genotype modulates striatal processing and long-term memory for items associated with reward and punishment. Neuropsychologia. vol 51. issue 11. 2014-05-08. PMID:23911780. |
these findings suggest that processing of appetitive and aversive motivation in the human striatum involve the dopaminergic system and that dopamine plays a role in memory for both types of motivational information. |
2014-05-08 |
2023-08-12 |
human |
| David Devos, Caroline Moreau, Kathy Dujardin, Ioav Cabantchik, Luc Defebvre, Regis Borde. New pharmacological options for treating advanced Parkinson's disease. Clinical therapeutics. vol 35. issue 10. 2014-05-07. PMID:24011636. |
given that the loss of dopamine in the striatum is the main pathochemical hallmark of pd, pharmacological treatment of the disease has focused on restoring dopaminergic neurotransmission and thus improving motor symptoms. |
2014-05-07 |
2023-08-12 |
Not clear |
| Regina Rumpel, Mesbah Alam, Alexander Klein, Meltem Özer, Maike Wesemann, Xingxing Jin, Joachim K Krauss, Kerstin Schwabe, Andreas Ratzka, Claudia Groth. Neuronal firing activity and gene expression changes in the subthalamic nucleus after transplantation of dopamine neurons in hemiparkinsonian rats. Neurobiology of disease. vol 59. 2014-05-05. PMID:23938762. |
we combined behavioral and histological findings with electrophysiological extracellular recordings in the stn, as well as qrt-pcr analyses of dopaminergic, gabaergic, and glutamatergic transporter and receptor genes in the striatum and the stn. |
2014-05-05 |
2023-08-12 |
rat |
| Karolina Pytka, Małgorzata Zygmunt, Barbara Filipe. [Pharmacotherapy of Parkinson's disease: progress or regress?]. Postepy higieny i medycyny doswiadczalnej (Online). vol 67. 2014-04-29. PMID:24018435. |
parkinson's disease (pd) is a chronic, progressive disease of the central nervous system (cns), characterized by a slow loss of dopaminergic neurons in the substantia nigra, leading to significant decrease in dopamine (da) levels in the striatum. |
2014-04-29 |
2023-08-12 |
Not clear |
| Bryan Killinger, Mrudang Shah, Anna Moszczynsk. Co-administration of betulinic acid and methamphetamine causes toxicity to dopaminergic and serotonergic nerve terminals in the striatum of late adolescent rats. Journal of neurochemistry. vol 128. issue 5. 2014-04-29. PMID:24151877. |
co-administration of betulinic acid and methamphetamine causes toxicity to dopaminergic and serotonergic nerve terminals in the striatum of late adolescent rats. |
2014-04-29 |
2023-08-12 |
rat |
| Bryan Killinger, Mrudang Shah, Anna Moszczynsk. Co-administration of betulinic acid and methamphetamine causes toxicity to dopaminergic and serotonergic nerve terminals in the striatum of late adolescent rats. Journal of neurochemistry. vol 128. issue 5. 2014-04-29. PMID:24151877. |
ba or meth alone did not decrease the levels of dopaminergic or serotonergic markers in the striatum whereas ba and meth together decreased these markers in a ba dose-dependent manner. |
2014-04-29 |
2023-08-12 |
rat |
| Bijay Aryal, Jin-Koo Lee, Hak Rim Kim, Hyung-Gun Ki. Alteration of striatal tetrahydrobiopterin in iron-induced unilateral model of Parkinson's disease. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology. vol 18. issue 2. 2014-04-23. PMID:24757374. |
it has been suggested that transition metal ions such as iron can produce an oxidative injuries to nigrostriatal dopaminergic neurons, like parkinson's disease (pd) and subsequent compensative increase of tetrahydrobiopterin (bh4) during the disease progression induces the aggravation of dopaminergic neurodegeneration in striatum. |
2014-04-23 |
2023-08-13 |
rat |
| Robert Christian Wolf, Markus Huber, Malte Sebastian Depping, Philipp Arthur Thomann, Martin Karner, Peter Lepping, Roland W Freudenman. Abnormal gray and white matter volume in delusional infestation. Progress in neuro-psychopharmacology & biological psychiatry. vol 46. 2014-04-22. PMID:23791615. |
case series and the response to anti-dopaminergic medication indicate disruptions in dopaminergic neurotransmission in the striatum (caudate, putamen), but did not allow for population-based inference. |
2014-04-22 |
2023-08-12 |
Not clear |
| Karin Löw, Patrick Aebischer, Bernard L Schneide. Direct and retrograde transduction of nigral neurons with AAV6, 8, and 9 and intraneuronal persistence of viral particles. Human gene therapy. vol 24. issue 6. 2014-04-17. PMID:23600720. |
surprisingly, single-stranded viral genomes persisted in nigral dopaminergic neurons within cell bodies and axon terminals in the striatum, and intact assembled aav capsid was enriched in nuclei of nigral neurons, 4 weeks after virus injections to the substantia nigra. |
2014-04-17 |
2023-08-12 |
Not clear |
| Karin Löw, Patrick Aebischer, Bernard L Schneide. Direct and retrograde transduction of nigral neurons with AAV6, 8, and 9 and intraneuronal persistence of viral particles. Human gene therapy. vol 24. issue 6. 2014-04-17. PMID:23600720. |
6-hydroxydopamine (6-ohda)-induced degeneration of dopaminergic neurons in the substantia nigra reduced the number of viral genomes in the striatum, in line with viral genome persistence in axon terminals. |
2014-04-17 |
2023-08-12 |
Not clear |
| Makiko Yamad. [Neuromolecular mechanism of the superiority illusion]. Brain and nerve = Shinkei kenkyu no shinpo. vol 66. issue 1. 2014-04-15. PMID:24371131. |
a functional connectivity between the frontal cortex and striatum, regulated by inhibitory dopaminergic neurotransmission, determines individual levels of the superiority illusion. |
2014-04-15 |
2023-08-12 |
human |
| Milica Cerovic, Raffaele d'Isa, Raffaella Tonini, Riccardo Brambill. Molecular and cellular mechanisms of dopamine-mediated behavioral plasticity in the striatum. Neurobiology of learning and memory. vol 105. 2014-04-11. PMID:23827407. |
by integrating glutamatergic signals from cortical and subcortical regions and dopaminergic signals from mesolimbic nuclei the striatum functions as an important neural substrate for procedural and motor learning as well as for reward-guided behaviors. |
2014-04-11 |
2023-08-12 |
Not clear |
| Oren Civier, Daniel Bullock, Ludo Max, Frank H Guenthe. Computational modeling of stuttering caused by impairments in a basal ganglia thalamo-cortical circuit involved in syllable selection and initiation. Brain and language. vol 126. issue 3. 2014-04-10. PMID:23872286. |
"neurally impaired" versions of the neurocomputational speech production model godiva were utilized to test two hypotheses: (1) that white-matter abnormalities disturb the circuit via corticostriatal projections carrying copies of executed motor commands and (2) that dopaminergic abnormalities disturb the circuit via the striatum. |
2014-04-10 |
2023-08-12 |
Not clear |