| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Candan Depboylu, Lukas Maurer, Andreas Matusch, Guido Hermanns, Andrea Windolph, Martin Béhé, Wolfgang H Oertel, Günter U Höglinge. Effect of long-term treatment with pramipexole or levodopa on presynaptic markers assessed by longitudinal [123I]FP-CIT SPECT and histochemistry. NeuroImage. vol 79. 2014-01-06. PMID:23631981. |
in 6-hydroxydopamine-lesioned mice, however, neither ld nor ppx significantly influenced the stably reduced fp-cit spect signal (ld: -66%; ppx: -66%; controls -66%), th-immunoreactivity (ld: -70%; ppx: -72%; controls: -77%) and dat-immunoreactivity (ld: -70%; ppx: -75%; controls: -75%) in the striatum or the number of th-positive cells in the substantia nigra (ld: -88%; ppx: -88%; controls: -86%), compared to lesioned mice without dopaminergic treatment. |
2014-01-06 |
2023-08-12 |
mouse |
| Akane Hayashi, Naoya Matsunaga, Hiroyuki Okazaki, Keisuke Kakimoto, Yoshinori Kimura, Hiroki Azuma, Eriko Ikeda, Takeshi Shiba, Mayumi Yamato, Ken-Ichi Yamada, Satoru Koyanagi, Shigehiro Ohd. A disruption mechanism of the molecular clock in a MPTP mouse model of Parkinson's disease. Neuromolecular medicine. vol 15. issue 2. 2014-01-03. PMID:23292542. |
parkinson's disease (pd) is a common neurodegenerative disorder that is characterized by the degeneration of dopaminergic neurons in the substantia nigra and dopamine depletion in the striatum. |
2014-01-03 |
2023-08-12 |
mouse |
| Hadi Fathi-Moghaddam, Mehdi Shafiee Ardestani, Mostafa Saffari, Ali Jabbari Arabzadeh, Mitra Elm. The selective cyclooxygenase-2 inhibitor, the compound 11b improves haloperidol induced catatonia by enhancing the striatum dopaminergic neurotransmission. Iranian journal of pharmaceutical research : IJPR. vol 9. issue 4. 2014-01-01. PMID:24381603. |
the selective cyclooxygenase-2 inhibitor, the compound 11b improves haloperidol induced catatonia by enhancing the striatum dopaminergic neurotransmission. |
2014-01-01 |
2023-08-12 |
Not clear |
| Hadi Fathi-Moghaddam, Mehdi Shafiee Ardestani, Mostafa Saffari, Ali Jabbari Arabzadeh, Mitra Elm. The selective cyclooxygenase-2 inhibitor, the compound 11b improves haloperidol induced catatonia by enhancing the striatum dopaminergic neurotransmission. Iranian journal of pharmaceutical research : IJPR. vol 9. issue 4. 2014-01-01. PMID:24381603. |
the compound 11b or 1-(phenyl)-5-(4-methylsulfonylphenyl)-2-ethylthioimidazole, in a dosage of 2, 4 and 8 mg/kg on haloperidol-induced catatonia was evaluated and compared to the standard drug scopolamine (1 mg/kg) by microanalysis of striatum dopaminergic neurotransmission. |
2014-01-01 |
2023-08-12 |
Not clear |
| Dorin Yael, Dagmar H Zeef, Daniel Sand, Anan Moran, Donald B Katz, Dana Cohen, Yasin Temel, Izhar Bar-Ga. Haloperidol-induced changes in neuronal activity in the striatum of the freely moving rat. Frontiers in systems neuroscience. vol 7. 2013-12-31. PMID:24379762. |
the striatum is the main input structure of the basal ganglia, integrating input from the cerebral cortex and the thalamus, which is modulated by midbrain dopaminergic input. |
2013-12-31 |
2023-08-12 |
rat |
| Allan Colver, Sarah Longwel. New understanding of adolescent brain development: relevance to transitional healthcare for young people with long term conditions. Archives of disease in childhood. vol 98. issue 11. 2013-12-10. PMID:23986559. |
new imaging techniques show striking changes in white and grey matter between 11 and 25 years of age, with increased connectivity between brain regions, and increased dopaminergic activity in the pre-frontal cortices, striatum and limbic system and the pathways linking them. |
2013-12-10 |
2023-08-12 |
Not clear |
| F Tison, G K Wenning, S E Daniel, N P Quin. The pathophysiology of parkinsonism in multiple system atrophy. European journal of neurology. vol 2. issue 5. 2013-12-03. PMID:24283724. |
this review indicates that the brains of msa patients who had parkinsonism in life show degeneration principally in anatomically related regions of the nigrostriatal dopaminergic pathway and of the striatum as well as in the globus pallidus. |
2013-12-03 |
2023-08-12 |
human |
| Bin Liu, Roberta Traini, Bryan Killinger, Bernard Schneider, Anna Moszczynsk. Overexpression of parkin in the rat nigrostriatal dopamine system protects against methamphetamine neurotoxicity. Experimental neurology. vol 247. 2013-11-26. PMID:23313192. |
at high doses, meth causes a selective degeneration of dopaminergic terminals in the striatum, sparing other striatal terminals and cell bodies. |
2013-11-26 |
2023-08-12 |
rat |
| Aleksandra Glavaski-Joksimovic, Martha C Boh. Mesenchymal stem cells and neuroregeneration in Parkinson's disease. Experimental neurology. vol 247. 2013-11-26. PMID:23542820. |
parkinson's disease (pd) is a prevalent neurodegenerative disorder characterized by a progressive and extensive loss of dopaminergic (da) neurons in the substantia nigra pars compacta (snpc) and their terminals in the striatum, which results in debilitating movement disorders. |
2013-11-26 |
2023-08-12 |
Not clear |
| Dimitri Ryczko, Swantje Grätsch, François Auclair, Catherine Dubé, Saskia Bergeron, Michael H Alpert, Jackson J Cone, Mitchell F Roitman, Simon Alford, Réjean Dubu. Forebrain dopamine neurons project down to a brainstem region controlling locomotion. Proceedings of the National Academy of Sciences of the United States of America. vol 110. issue 34. 2013-11-26. PMID:23918379. |
by using triple labeling, we found that dopaminergic cells from the pt not only project an ascending pathway to the striatum, but send a descending projection to the mlr. |
2013-11-26 |
2023-08-12 |
monkey |
| Han-Sam Cho, Mal-Soon Shin, Wook Song, Tae-Won Jun, Baek-Vin Lim, Young-Pyo Kim, Chang-Ju Ki. Treadmill exercise alleviates short-term memory impairment in 6-hydroxydopamine-induced Parkinson's rats. Journal of exercise rehabilitation. vol 9. issue 3. 2013-11-26. PMID:24278884. |
in the present results, extensive degeneration of the dopaminergic neurons in the substantia nigra with loss of dopaminergic fibers in the striatum were produced in the rats without treadmill running, which resulted in short-term memory impairment. |
2013-11-26 |
2023-08-12 |
rat |
| Chang-Youl Park, Shin-Ho Lee, Bo-Kyun Kim, Mal-Soon Shin, Chang-Ju Kim, Hong Ki. Treadmill exercise ameliorates impairment of spatial learning ability through enhancing dopamine expression in hypoxic ischemia brain injury in neonatal rats. Journal of exercise rehabilitation. vol 9. issue 4. 2013-11-26. PMID:24278893. |
we determined the effects of treadmill exercise on survival of dopamine neurons in the substantia nigra and dopaminergic fibers in the striatum after hypoxic ischemia brain injury. |
2013-11-26 |
2023-08-12 |
rat |
| Chang-Youl Park, Shin-Ho Lee, Bo-Kyun Kim, Mal-Soon Shin, Chang-Ju Kim, Hong Ki. Treadmill exercise ameliorates impairment of spatial learning ability through enhancing dopamine expression in hypoxic ischemia brain injury in neonatal rats. Journal of exercise rehabilitation. vol 9. issue 4. 2013-11-26. PMID:24278893. |
in this study, hypoxic ischemia injury caused loss of dopamine neurons in the substantia nigra and dopaminergic fibers in the striatum. |
2013-11-26 |
2023-08-12 |
rat |
| J A Priebe, P Rieckmann, S Lautenbache. [Central pain processing and Parkinson's disease. Epidemiology, physiology, and experimental results issuing pain processing]. Schmerz (Berlin, Germany). vol 26. issue 6. 2013-11-19. PMID:23052966. |
based on a review of the literature, it is postulated that dysfunction in endogenous pain inhibition caused by dopaminergic deficiency in the basal ganglia, especially in the striatum, but also in mesolimbic areas is a main pathophysiological mechanism involved in nociceptive abnormalities in pd. |
2013-11-19 |
2023-08-12 |
Not clear |
| Mohammad Reza Aghasadeghi, Seyyed Davar Siadat, Mehdi Shafiee Ardestani, Ali Jabbari Arabzadeh, Mitra Elmi, Hadi Fathi Moghadda. Selective cyclooxygenase-2 inhibitor compound 11b improves haloperidol-induced catatonia by enhancing the striatum dopaminergic neurotransmission. Iranian journal of pharmaceutical research : IJPR. vol 11. issue 1. 2013-11-19. PMID:24250457. |
selective cyclooxygenase-2 inhibitor compound 11b improves haloperidol-induced catatonia by enhancing the striatum dopaminergic neurotransmission. |
2013-11-19 |
2023-08-12 |
Not clear |
| Mohammad Reza Aghasadeghi, Seyyed Davar Siadat, Mehdi Shafiee Ardestani, Ali Jabbari Arabzadeh, Mitra Elmi, Hadi Fathi Moghadda. Selective cyclooxygenase-2 inhibitor compound 11b improves haloperidol-induced catatonia by enhancing the striatum dopaminergic neurotransmission. Iranian journal of pharmaceutical research : IJPR. vol 11. issue 1. 2013-11-19. PMID:24250457. |
in this study, the effect of orally, acutely and sub-chronically administrations of compound 11b [1-(phenyl)-5-(4-methylsulfonylphenyl)-2-ethylthioimidazole] (2, 4 and 8 mg/kg), a newly selective cox-2 inhibitor, was investigated against the haloperidol-induced catatonia phenomenon comparing to the standard drug scopolamine (1 mg/kg) followed by microdialysis analysis of striatum dopaminergic neurotransmission. |
2013-11-19 |
2023-08-12 |
Not clear |
| Satoshi Fujita, Risako Kato, Yilong Cui, Masanori Terakado, Kurando Suga, Noriaki Koshikawa, Masayuki Kobayash. Apomorphine-induced modulation of neural activities in the ventrolateral striatum of rats. Synapse (New York, N.Y.). vol 67. issue 7. 2013-11-07. PMID:23401143. |
the dopaminergic system in the ventrolateral portion of the striatum (svl), part of the basal ganglia, regulates orofacial movements; bilateral co-stimulation of both dopamine d1 -like and d2 -like receptors elicits repetitive jaw movements in rats. |
2013-11-07 |
2023-08-12 |
rat |
| G Giordano, L Tait, C E Furlong, T B Cole, T J Kavanagh, L G Cost. Gender differences in brain susceptibility to oxidative stress are mediated by levels of paraoxonase-2 expression. Free radical biology & medicine. vol 58. 2013-11-01. PMID:23376469. |
in mouse brain, pon2 levels are highest in dopaminergic areas (e.g., striatum) and are higher in astrocytes than in neurons. |
2013-11-01 |
2023-08-12 |
mouse |
| Yen Yu, Thomas H B FitzGerald, Karl J Fristo. Working memory and anticipatory set modulate midbrain and putamen activity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 35. 2013-10-28. PMID:23986240. |
based on the known role of dopamine in cognitive flexibility and working memory updating, we hypothesized that differences in anticipatory set would be manifest in the dopaminergic midbrain and striatum. |
2013-10-28 |
2023-08-12 |
human |
| Yen Yu, Thomas H B FitzGerald, Karl J Fristo. Working memory and anticipatory set modulate midbrain and putamen activity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 35. 2013-10-28. PMID:23986240. |
consistent with our predictions, we identified sustained activation in the dopaminergic midbrain and the striatum, associated with anticipations of high versus low updating probability. |
2013-10-28 |
2023-08-12 |
human |