Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Xuefeng Tan, Lei Zhang, JianBing Qin, Meiling Tian, Huixia Zhu, Chuanming Dong, Heyan Zhao, Guohua Ji. Transplantation of neural stem cells co-transfected with Nurr1 and Brn4 for treatment of Parkinsonian rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 31. issue 1. 2013-05-30. PMID:23085081. |
importantly, co-expression of nurr1 and brn4 in nscs significantly increased the maturity and viability of dopaminergic neurons, further raised the da amount in the striatum and reversed the behavioral deficit of the pd rats. |
2013-05-30 |
2023-08-12 |
rat |
Mei Yu, Haiyun Suo, Ming Liu, Lei Cai, Jie Liu, Yufang Huang, Jing Xu, Yancong Wang, Cuiqing Zhu, Jian Fei, Fang Huan. NRSF/REST neuronal deficient mice are more vulnerable to the neurotoxin MPTP. Neurobiology of aging. vol 34. issue 3. 2013-05-24. PMID:22766071. |
also, the reduction of tyrosine hydroxylase protein in the striatum and the loss of dopaminergic neurons in the substantia nigra were more severe in the cko mice. |
2013-05-24 |
2023-08-12 |
mouse |
Makiko Yamada, Lucina Q Uddin, Hidehiko Takahashi, Yasuyuki Kimura, Keisuke Takahata, Ririko Kousa, Yoko Ikoma, Yoko Eguchi, Harumasa Takano, Hiroshi Ito, Makoto Higuchi, Tetsuya Suhar. Superiority illusion arises from resting-state brain networks modulated by dopamine. Proceedings of the National Academy of Sciences of the United States of America. vol 110. issue 11. 2013-05-23. PMID:23440209. |
resting-state functional connectivity between the frontal cortex and striatum regulated by inhibitory dopaminergic neurotransmission determines individual levels of the superiority illusion. |
2013-05-23 |
2023-08-12 |
human |
Oytun Erbaş, Fatih Oltulu, Dilek Taşkira. Amelioration of rotenone-induced dopaminergic cell death in the striatum by oxytocin treatment. Peptides. vol 38. issue 2. 2013-05-14. PMID:22985856. |
amelioration of rotenone-induced dopaminergic cell death in the striatum by oxytocin treatment. |
2013-05-14 |
2023-08-12 |
rat |
Shuhua Yang, Qing Gao, Lihua Bao, Jing Zhang, Yanlai Hu, Lujun Bing, Jinlong Sun, Jing Hao, Chao Chen, Shangzhi Li, W S Poon, Jinhao Sun, Yingmao Ga. Striatal extracts promote the dopaminergic differentiation of GFP-bone mesenchymal stem cells. Neuroscience letters. vol 530. issue 2. 2013-05-09. PMID:23069670. |
because the striatum is the target tissue for the projection of da neurons in the midbrain, we investigated whether its extracts could promote the dopaminergic differentiation of bmscs. |
2013-05-09 |
2023-08-12 |
mouse |
Yasukazu Hozumi, Masahiko Watanabe, Kaoru Got. Signaling cascade of diacylglycerol kinase β in the pituitary intermediate lobe: dopamine D2 receptor/phospholipase Cβ4/diacylglycerol kinase β/protein kinase Cα. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 58. issue 2. 2013-05-08. PMID:19826069. |
we have previously shown that diacylglycerol kinase β (dgkβ) is coexpressed with dopamine d1 and d2 receptors in medium spiny neurons of the striatum, suggesting a plausible implication of dgkβ in dopaminergic transmission. |
2013-05-08 |
2023-08-12 |
Not clear |
Karin Foerde, Erin Kendall Braun, Daphna Shoham. A trade-off between feedback-based learning and episodic memory for feedback events: evidence from Parkinson's disease. Neuro-degenerative diseases. vol 11. issue 2. 2013-04-30. PMID:23036965. |
parkinson's disease (pd) is characterized by a loss of dopaminergic projections to the striatum, leading to both motor and cognitive impairments. |
2013-04-30 |
2023-08-12 |
Not clear |
Maryna Baydyuk, Yuxiang Xie, Lino Tessarollo, Baoji X. Midbrain-derived neurotrophins support survival of immature striatal projection neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 8. 2013-04-24. PMID:23426664. |
here we report that brain-derived neurotrophic factor and neurotrophin-3 are anterogradely transported from midbrain dopaminergic neurons and support the survival of immature msns of the indirect and direct pathways, respectively, in the developing mouse striatum and lge. |
2013-04-24 |
2023-08-12 |
mouse |
OrhanTansel Korkmaz, Hakan Ay, Emel Ulupinar, Neşe Tunçe. Vasoactive intestinal peptide enhances striatal plasticity and prevents dopaminergic cell loss in Parkinsonian rats. Journal of molecular neuroscience : MN. vol 48. issue 3. 2013-04-19. PMID:22544516. |
dopaminergic inputs from the snc innervate the medium spiny neurons of the striatum and modulate the spontaneous activity of the primary output nuclei of the basal ganglia, globus pallidus interna, and substantia nigra pars reticulata. |
2013-04-19 |
2023-08-12 |
rat |
OrhanTansel Korkmaz, Hakan Ay, Emel Ulupinar, Neşe Tunçe. Vasoactive intestinal peptide enhances striatal plasticity and prevents dopaminergic cell loss in Parkinsonian rats. Journal of molecular neuroscience : MN. vol 48. issue 3. 2013-04-19. PMID:22544516. |
the 6-ohda significantly decreased the total number of dopaminergic neurons, branching, and spine density of the medium spiny neurons in the striatum. |
2013-04-19 |
2023-08-12 |
rat |
Takao Nozaki, Kenji Sugiyama, Shunsuke Yagi, Etsuji Yoshikawa, Toshihiko Kanno, Tetsuya Asakawa, Tae Ito, Tatsuhiro Terada, Hiroki Namba, Yasuomi Ouch. Effect of subthalamic nucleus stimulation during exercise on the mesolimbocortical dopaminergic region in Parkinson's disease: a positron emission tomography study. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 33. issue 3. 2013-04-19. PMID:23211966. |
the lack of dopamine release in the putamen and the significant dopamine release in the ventromedial striatum by stn-dbs during exercise indicated dopaminergic activation occurring in the motivational circuit during action, suggesting a compensatory functional activation of the motor loop from the nonmotor to the motor loop system. |
2013-04-19 |
2023-08-12 |
Not clear |
Susanne Bäck, Johan Peränen, Emilia Galli, Päivi Pulkkila, Liina Lonka-Nevalaita, Tuulia Tamminen, Merja H Voutilainen, Atso Raasmaja, Mart Saarma, Pekka T Männistö, Raimo K Tuomine. Gene therapy with AAV2-CDNF provides functional benefits in a rat model of Parkinson's disease. Brain and behavior. vol 3. issue 2. 2013-03-28. PMID:23532969. |
two weeks after aav2 vector injection, 6-ohda was injected into the rat striatum, creating a progressive degeneration of the nigrostriatal dopaminergic system. |
2013-03-28 |
2023-08-12 |
mouse |
Anh H Pham, Shuxia Meng, Quynh N Chu, David C Cha. Loss of Mfn2 results in progressive, retrograde degeneration of dopaminergic neurons in the nigrostriatal circuit. Human molecular genetics. vol 21. issue 22. 2013-03-26. PMID:22859504. |
these motor deficits are preceded by the loss of dopaminergic terminals in the striatum. |
2013-03-26 |
2023-08-12 |
mouse |
Javier Sanchez-Betancourt, Veronica Anaya-Martínez, Ana Luisa Gutierrez-Valdez, José Luis Ordoñez-Librado, Enrique Montiel-Flores, Jesús Espinosa-Villanueva, Leonardo Reynoso-Erazo, Maria Rosa Avila-Cost. Manganese mixture inhalation is a reliable Parkinson disease model in rats. Neurotoxicology. vol 33. issue 5. 2013-03-21. PMID:22975423. |
the mixture of mncl(2)/mn(oac)(3) caused alterations in the motor tests, 75.95% loss of snc dopaminergic neurons, and no cell alterations in globus pallidus or striatum. |
2013-03-21 |
2023-08-12 |
mouse |
Noelia Granado, Sara Ares-Santos, Rosario Moratall. Methamphetamine and Parkinson's disease. Parkinson's disease. vol 2013. 2013-03-12. PMID:23476887. |
in rodents, methamphetamine exposure damages dopaminergic neurons in the substantia nigra, resulting in a significant loss of dopamine in the striatum. |
2013-03-12 |
2023-08-12 |
human |
Claudia Kühne, Oliver Puk, Jochen Graw, Martin Hrabě de Angelis, Günther Schütz, Wolfgang Wurst, Jan M Deussin. Visualizing corticotropin-releasing hormone receptor type 1 expression and neuronal connectivities in the mouse using a novel multifunctional allele. The Journal of comparative neurology. vol 520. issue 14. 2013-03-08. PMID:22886732. |
thereby, we were able to visualize projections of crhr1 neurons such as glutamatergic and dopaminergic afferent connections of the striatum and gabaergic crhr1-expressing neurons located within its patch compartment. |
2013-03-08 |
2023-08-12 |
mouse |
Sung-Il Ki. Neuroscientific model of motivational process. Frontiers in psychology. vol 4. 2013-03-06. PMID:23459598. |
these three sub processes interact with each other by sending reward prediction error signals through dopaminergic pathway from the striatum and to the prefrontal cortex. |
2013-03-06 |
2023-08-12 |
Not clear |
Michal Kirshner, Ronit Galron, Dan Frenkel, Gil Mandelbaum, Yosef Shiloh, Zhao-Qi Wang, Ari Barzila. Malfunctioning DNA damage response (DDR) leads to the degeneration of nigro-striatal pathway in mouse brain. Journal of molecular neuroscience : MN. vol 46. issue 3. 2013-02-25. PMID:21922345. |
earlier reports show that atm-deficient mice exhibit severe degeneration of tyrosine hydroxylase (th)-positive dopaminergic nigro-striatal neurons and their terminals in the striatum. |
2013-02-25 |
2023-08-12 |
mouse |
Frederico C Pereira, Teresa Cunha-Oliveira, Sofia D Viana, Ana S Travassos, Sara Nunes, Carlos Silva, Rui Daniel Prediger, A Cristina Rego, Syed F Ali, Carlos Alberto Fontes Ribeir. Disruption of striatal glutamatergic/GABAergic homeostasis following acute methamphetamine in mice. Neurotoxicology and teratology. vol 34. issue 5. 2013-02-25. PMID:22884891. |
this methamphetamine regimen also produced dopaminergic terminal degeneration in the striatum, as evidenced by dopamine and tyrosine hydroxylase depletion. |
2013-02-25 |
2023-08-12 |
mouse |
Yukio Yamamura, Ryoma Morigaki, Jiro Kasahara, Hironori Yokoyama, Akie Tanabe, Shinya Okita, Hidetaka Koizumi, Shinji Nagahiro, Ryuji Kaji, Satoshi Got. Dopamine signaling negatively regulates striatal phosphorylation of Cdk5 at tyrosine 15 in mice. Frontiers in cellular neuroscience. vol 7. 2013-02-20. PMID:23420105. |
we here report that cdk5 with tyr15 phosphorylation (cdk5-ptyr15) is enriched in the mouse striatum, where dopaminergic stimulation inhibited phosphorylation of tyr15-cdk5 by acting through the d2 class dopamine receptors. |
2013-02-20 |
2023-08-12 |
mouse |