Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Natasha Luquin, Salvador Sierra, Alberto J Rico, Virginia Gómez-Bautista, Elvira Roda, Lorena Conte-Perales, Rafael Franco, Peter McCormick, José L Labandeira-García, José L Lancieg. Unmasking adenosine 2A receptors (A2ARs) in monkey basal ganglia output neurons using cholera toxin subunit B (CTB). Neurobiology of disease. vol 47. issue 3. 2012-11-29. PMID:22659306. |
the a(2a)r has become a therapeutic target in parkinson disease due to its functional role in the striatum, capable of modulating dopaminergic neurotransmission in the basal ganglia. |
2012-11-29 |
2023-08-12 |
monkey |
Anne Pankow, Astrid Knobel, Martin Voss, Andreas Hein. Neurobiological correlates of delusion: beyond the salience attribution hypothesis. Neuropsychobiology. vol 66. issue 1. 2012-11-27. PMID:22797275. |
based on studies revealing dopamine dysfunction in addiction research, it has been suggested that phasic or chaotic firing of dopaminergic neurons projecting to the (ventral) striatum attribute salience to otherwise irrelevant stimuli and thus contribute to delusional mood and delusion formation. |
2012-11-27 |
2023-08-12 |
Not clear |
Jonghan Kim, Yuan Li, Peter D Buckett, Mark Böhlke, Khristy J Thompson, Masaya Takahashi, Timothy J Maher, Marianne Wessling-Resnic. Iron-responsive olfactory uptake of manganese improves motor function deficits associated with iron deficiency. PloS one. vol 7. issue 3. 2012-11-19. PMID:22479410. |
although tissue dopamine concentrations were similar in the striatum, dopamine transporter (dat) and dopamine receptor d(1) (d1r) levels were reduced and dopamine receptor d(2) (d2r) levels were increased in manganese-instilled rats, suggesting that manganese-induced changes in post-synaptic dopaminergic signaling contribute to the compensatory effect. |
2012-11-19 |
2023-08-12 |
rat |
Yuexiang Wang, Adrian C Michae. Microdialysis probes alter presynaptic regulation of dopamine terminals in rat striatum. Journal of neuroscience methods. vol 208. issue 1. 2012-11-13. PMID:22546476. |
the insertion of microdialysis probes into the rat striatum disrupts dopaminergic activity near the probe track. |
2012-11-13 |
2023-08-12 |
rat |
Flávia Doyle, Francisco Cardoso, Lívia Lopes, Marina Mendes, Fernando Dias, Luciana Cruz, Rubens Tavares, Aroldo Camargos, Márcia Carneiro, Camila Dias-Lopes, Carlos Chávez-Olórtegu. Infusion of Sydenham's chorea antibodies in striatum with up-regulated dopaminergic receptors: a pilot study to investigate the potential of SC antibodies to increase dopaminergic activity. Neuroscience letters. vol 523. issue 2. 2012-11-13. PMID:22781496. |
infusion of sydenham's chorea antibodies in striatum with up-regulated dopaminergic receptors: a pilot study to investigate the potential of sc antibodies to increase dopaminergic activity. |
2012-11-13 |
2023-08-12 |
rat |
Luke S Poth, Bryan P O'Connell, Janet L McDermott, Dean E Dluze. Nomifensine alters sex differences in striatal dopaminergic function. Synapse (New York, N.Y.). vol 66. issue 8. 2012-11-09. PMID:22389194. |
taken together these results demonstrate the critical role played by catecholamine transporters in sex differences of dopaminergic function and suggest that this may involve the dopamine transporter, due to its high concentrations within the striatum. |
2012-11-09 |
2023-08-12 |
mouse |
A Garcia-Falgueras, M M Castillo-Ruiz, T Put, A Tobeña, A Fernández-Terue. Differential hippocampal neuron density between inbred Roman high- (low anxious) and low-avoidance (high anxious) rats. Neuroscience letters. vol 522. issue 1. 2012-11-09. PMID:22698586. |
in rats of these two strains/lines previous brain studies have been performed, specifically in the striatum, the mesencephalic dopaminergic areas and the prefrontal cortex, as these brain areas are the classical ones for their critical role in sensitization and may play a role in the well-characterized anxiety response. |
2012-11-09 |
2023-08-12 |
rat |
A Bueno-Nava, R Gonzalez-Pina, A Alfaro-Rodriguez, A Avila-Luna, E Arch-Tirado, M Alonso-Spilsbur. The selective inhibition of the D₁ dopamine receptor results in an increase of metabolized dopamine in the rat striatum. Neurochemical research. vol 37. issue 8. 2012-11-05. PMID:22573387. |
our aim was to study the specific role of the postsynaptic d(1) receptors on dopaminergic response and analyze the metabolized dopamine (da) in the rat striatum. |
2012-11-05 |
2023-08-12 |
rat |
Mary P Heyer, Amar K Pani, Richard J Smeyne, Paul J Kenny, Guoping Fen. Normal midbrain dopaminergic neuron development and function in miR-133b mutant mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 32. 2012-10-26. PMID:22875923. |
dopamine levels are unchanged in the striatum, while expression of dopaminergic genes, including pitx3, is also unaffected. |
2012-10-26 |
2023-08-12 |
mouse |
Wayne A Cass, Laura E Peters, Anita M Fletcher, David M Yure. Evoked dopamine overflow is augmented in the striatum of calcitriol treated rats. Neurochemistry international. vol 60. issue 2. 2012-10-19. PMID:22133428. |
these results suggest that systemically administered calcitriol can upregulate dopaminergic release processes in the striatum and da levels in the substantia nigra. |
2012-10-19 |
2023-08-12 |
rat |
Wayne A Cass, Laura E Peters, Anita M Fletcher, David M Yure. Evoked dopamine overflow is augmented in the striatum of calcitriol treated rats. Neurochemistry international. vol 60. issue 2. 2012-10-19. PMID:22133428. |
the ability of calcitriol to lead to augmented da release in the striatum suggests that calcitriol may be beneficial in disease processes involving dopaminergic dysfunction. |
2012-10-19 |
2023-08-12 |
rat |
Sang-hyun Baik, Heung Sik Yoon, Sang Eun Kim, Sang Hee Ki. Extraversion and striatal dopaminergic receptor availability in young adults: an [18F]fallypride PET study. Neuroreport. vol 23. issue 4. 2012-10-18. PMID:22257904. |
we investigated whether dopaminergic receptor availability in the striatum was directly associated with individual differences in extraversion using the high-affinity radiotracer [¹⁸f]fallypride and pet. |
2012-10-18 |
2023-08-12 |
human |
Sang-hyun Baik, Heung Sik Yoon, Sang Eun Kim, Sang Hee Ki. Extraversion and striatal dopaminergic receptor availability in young adults: an [18F]fallypride PET study. Neuroreport. vol 23. issue 4. 2012-10-18. PMID:22257904. |
both region of interest and voxel-based whole-brain analyses showed that extraversion was significantly correlated with dopaminergic receptor availability in the striatum bilaterally. |
2012-10-18 |
2023-08-12 |
human |
Yu-bing Dai, Xin-jie Tan, Wan-fu Wu, Margaret Warner, Jan-Åke Gustafsso. Liver X receptor β protects dopaminergic neurons in a mouse model of Parkinson disease. Proceedings of the National Academy of Sciences of the United States of America. vol 109. issue 32. 2012-10-15. PMID:22826221. |
administration of the lxr agonist gw3965 to mptp-treated wt mice protected against loss of dopaminergic neurons and of dopaminergic fibers projecting to the striatum, and resulted in fewer activated microglia and astroglia. |
2012-10-15 |
2023-08-12 |
mouse |
Pierre Berthet, Jeanette Hellgren-Kotaleski, Anders Lansne. Action selection performance of a reconfigurable basal ganglia inspired model with Hebbian-Bayesian Go-NoGo connectivity. Frontiers in behavioral neuroscience. vol 6. 2012-10-15. PMID:23060764. |
the dopaminergic signal to striatum, the input stage of the bg, has been commonly described as coding a reward prediction error (rpe), i.e., the difference between the predicted and actual reward. |
2012-10-15 |
2023-08-12 |
monkey |
Vanessa Franco, Robert S Turne. Testing the contributions of striatal dopamine loss to the genesis of parkinsonian signs. Neurobiology of disease. vol 47. issue 1. 2012-10-12. PMID:22498034. |
the diverse and independently-varying signs of parkinson's disease (pd) are often attributed to one simple mechanism: degeneration of the dopaminergic innervation of the posterolateral striatum. |
2012-10-12 |
2023-08-12 |
monkey |
Jinming Zhang, Xiaojun Zhang, Yungang Li, Jiahe Tia. Simple, rapid and reliable preparation of [¹¹C]-(+)-α-DTBZ of high quality for routine applications. Molecules (Basel, Switzerland). vol 17. issue 6. 2012-10-09. PMID:22728363. |
[¹¹c]-(+)-α-dtbz has been used as a marker of dopaminergic terminal densities in human striatum and expressed in islet beta cells in the pancreas. |
2012-10-09 |
2023-08-12 |
human |
Hong Yuan, Li-Wu Liang, Zheng-Jing Chen, Hui-Ru Ji, Mei-Kang Wang, Hai-Ying Zhang, Cao Li, Jian-Yang X. R-apomorphine protects against 6-hydroxydopamine-induced nigrostriatal damage in rat. Neuroscience bulletin. vol 22. issue 6. 2012-10-02. PMID:17690718. |
objective the aim of the present study was not only to assess the retrograde degenerative changes in the dopaminergic neurons of the substantia nigra (sn) and ventral tegmental area (vta) after injection of 6-hydroxydopamine (6-ohda) into the striatum, but also to use this 6-ohda model of parkinson's disease to explore the possible neuroprotective effect of r-apomorphine (r-apo). |
2012-10-02 |
2023-08-12 |
rat |
C Fernández, K De La Cuétara, O Castellanos, O González, N Nunez, L Alvarez, R Macías, A Torres, R Pernas, J Soto, H Molina, W Sole. Brain aging and neurotransplantation. I. Nigral cell suspension graft to aged rodent striatum and motor disabilities. Archives of gerontology and geriatrics. vol 19 Suppl 1. 2012-10-02. PMID:18649843. |
deficient rats were divided in two groups: one group received dissociated fetal dopaminergic cells from ventral mesencephalon (e12-e14) to striatum, whereas the other group having the same level of impairment, was followed without any graft and served as age-matched controls. |
2012-10-02 |
2023-08-12 |
rat |
B Berger, J Nguyen-Legros, A M Thierr. Demonstration of horseradish peroxidase and fluorescent catecholamines in the same neuron. Neuroscience letters. vol 9. issue 4. 2012-10-02. PMID:19605235. |
after hrp injection into the striatum or into the nucleus accumbens of the rat, both fluorescent dopaminergic neurons labelled with hrp and non-fluorescent neurons labelled with hrp were observed in the substantia nigra or in the ventral tegmental area, respectively. |
2012-10-02 |
2023-08-12 |
rat |