| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Diego Centonze, Enrico Bracci, Antonio Pisani, Paolo Gubellini, Giorgio Bernardi, Paolo Calabres. Activation of dopamine D1-like receptors excites LTS interneurons of the striatum. The European journal of neuroscience. vol 15. issue 12. 2002-09-04. PMID:12099911. |
along with projection cells, striatal interneurons receive dense dopaminergic innervation from midbrain neurons, thus, also suggesting that these intrinsic cells represent a synaptic target for da action in the striatum. |
2002-09-04 |
2023-08-12 |
rat |
| D Chichung Lie, Gustavo Dziewczapolski, Andrew R Willhoite, Brian K Kaspar, Clifford W Shults, Fred H Gag. The adult substantia nigra contains progenitor cells with neurogenic potential. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 15. 2002-09-03. PMID:12151543. |
one current therapy aims at exogenous cellular replacement of dopaminergic function by transplanting fetal midbrain cells into the striatum, the main projection area of the sn. |
2002-09-03 |
2023-08-12 |
Not clear |
| Samina S Riaz, Eric Jauniaux, Gerald M Stern, Henry F Bradfor. The controlled conversion of human neural progenitor cells derived from foetal ventral mesencephalon into dopaminergic neurons in vitro. Brain research. Developmental brain research. vol 136. issue 1. 2002-08-27. PMID:12036514. |
the controlled conversion of human neural progenitor cells derived from foetal ventral mesencephalon into dopaminergic neurons in vitro. |
2002-08-27 |
2023-08-12 |
human |
| Samina S Riaz, Eric Jauniaux, Gerald M Stern, Henry F Bradfor. The controlled conversion of human neural progenitor cells derived from foetal ventral mesencephalon into dopaminergic neurons in vitro. Brain research. Developmental brain research. vol 136. issue 1. 2002-08-27. PMID:12036514. |
here, the controlled conversion of human foetal progenitor cells derived from ventral mesencephalon into dopaminergic neurons is reported. |
2002-08-27 |
2023-08-12 |
human |
| Andreas C Tomac, Alan D Agulnick, Norman Haughey, Chen-Fu Chang, Yajun Zhang, Cristina Bäckman, Marisela Morales, Mark P Mattson, Yun Wang, Heiner Westphal, Barry J Hoffe. Effects of cerebral ischemia in mice deficient in Persephin. Proceedings of the National Academy of Sciences of the United States of America. vol 99. issue 14. 2002-08-08. PMID:12093930. |
persephin (pspn), a recently cloned member of the transforming growth factor-beta superfamily (tgf-beta) and glial cell line-derived neurotrophic factor (gdnf) subfamily, is distributed throughout the nervous system at extremely low levels and is thought to function as a survival factor for midbrain dopaminergic and spinal motor neurons in vivo. |
2002-08-08 |
2023-08-12 |
mouse |
| Doreen Siu Yi Leung, Klaus Unsicker, Bernhard Reus. Expression and developmental regulation of gap junction connexins cx26, cx32, cx43 and cx45 in the rat midbrain-floor. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 20. issue 1. 2002-08-07. PMID:12008076. |
we have investigated expression of cx26, cx32, cx43, and cx45 in the midbrain floor, where nigrostriatal dopaminergic neurons originate and differentiate. |
2002-08-07 |
2023-08-12 |
rat |
| Doreen Siu Yi Leung, Klaus Unsicker, Bernhard Reus. Expression and developmental regulation of gap junction connexins cx26, cx32, cx43 and cx45 in the rat midbrain-floor. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 20. issue 1. 2002-08-07. PMID:12008076. |
taken together, our results reveal that expression and ir of cx in the midbrain floor and dopaminergic neurons, respectively, follow cx-type specific patterns that temporally coincide with important steps of midbrain morphogenesis, as e.g. |
2002-08-07 |
2023-08-12 |
rat |
| b' M E G\\xc3\\xb6tz, E Koutsilieri, P Riederer, S Ceccatelli, E Dar\\xc3\\xa. Methylmercury induces neurite degeneration in primary culture of mouse dopaminergic mesencephalic cells. Journal of neural transmission (Vienna, Austria : 1996). vol 109. issue 5-6. 2002-08-06. PMID:12111452.' |
in the present study we have used epifluorescence microscopy and confocal microscopy to investigate the alterations induced by mehg in primary da (dopaminergic) cells isolated from the ventral mesencephalon of cd-1 embryonic mice and cultured for six days in vitro. |
2002-08-06 |
2023-08-12 |
mouse |
| G Gille, W-D Rausch, S-T Hung, R Moldzio, B Janetzky, H P Hundemer, T Kolter, H Reichman. Pergolide protects dopaminergic neurons in primary culture under stress conditions. Journal of neural transmission (Vienna, Austria : 1996). vol 109. issue 5-6. 2002-08-06. PMID:12111455. |
in primary cultures from mouse mesencephalon we show that pergolide, a preferential d(2) agonist enhanced the survival of healthy dopaminergic neurons at low concentrations of 0.001 microm. |
2002-08-06 |
2023-08-12 |
mouse |
| K Kitahama, A Jouvet, M Fujimiya, I Nagatsu, R Ara. 5-Hydroxytryptophan (5-HTP) uptake and decarboxylation in the kitten brain. Journal of neural transmission (Vienna, Austria : 1996). vol 109. issue 5-6. 2002-08-06. PMID:12111460. |
after loading of 5-htp and monoamine oxidase inhibitor (maoi), we could demonstrate 5-ht-immunoreactivity (ir) not only in hypothalamic and midbrain dopaminergic (da) cell bodies, but also in na ones located in the pons and medulla oblongata of the new born kitten aged from 1 to 7 days. |
2002-08-06 |
2023-08-12 |
Not clear |
| Seiji Nishino, Beth Ripley, Emmanuel Mignot, Kathleen L Benson, Vincent P Zarcon. CSF hypocretin-1 levels in schizophrenics and controls: relationship to sleep architecture. Psychiatry research. vol 110. issue 1. 2002-07-31. PMID:12007588. |
hypocretin is known to excite midbrain dopaminergic neurons and to induce hyperactivity and stereotypy in animals. |
2002-07-31 |
2023-08-12 |
human |
| Anh Hai Tran, Ryoi Tamura, Teruko Uwano, Tsuneyuki Kobayashi, Motoya Katsuki, Gen Matsumoto, Taketoshi On. Altered accumbens neural response to prediction of reward associated with place in dopamine D2 receptor knockout mice. Proceedings of the National Academy of Sciences of the United States of America. vol 99. issue 13. 2002-07-19. PMID:12084937. |
midbrain dopaminergic activity seems to be important in forming the prediction of future events such as rewards. |
2002-07-19 |
2023-08-12 |
mouse |
| François Georges, Gary Aston-Jone. Activation of ventral tegmental area cells by the bed nucleus of the stria terminalis: a novel excitatory amino acid input to midbrain dopamine neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 12. 2002-07-15. PMID:12077212. |
we examined the role of excitatory amino acids (eaas) in the activation of midbrain dopaminergic (da) neurons evoked by stimulation of the ventromedial and ventrolateral (subcommissural) bed nucleus of the stria terminalis (vbnst). |
2002-07-15 |
2023-08-12 |
rat |
| Long Ding, David J Perke. Dopamine modulates excitability of spiny neurons in the avian basal ganglia. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 12. 2002-07-15. PMID:12077216. |
like their mammalian counterparts, they receive dense dopaminergic innervation from the midbrain, but the physiological functions of this projection remain unclear. |
2002-07-15 |
2023-08-12 |
Not clear |
| M Yoshimura, T Yamamoto, N Iso-o, I Imafuku, T Momose, I Shirouzu, S Kwak, I Kanazaw. Hemiparkinsonism associated with a mesencephalic tumor. Journal of the neurological sciences. vol 197. issue 1-2. 2002-07-03. PMID:11997073. |
these findings are consistent with a dysfunction in the left nigrostriatal dopaminergic pathway that is presumably induced by the cystic mass in the left midbrain. |
2002-07-03 |
2023-08-12 |
Not clear |
| Simonetta Prisco, Silvia Natoli, Giorgio Bernardi, Nicola B Mercur. Group I metabotropic glutamate receptors activate burst firing in rat midbrain dopaminergic neurons. Neuropharmacology. vol 42. issue 3. 2002-06-27. PMID:11897107. |
group i metabotropic glutamate receptors activate burst firing in rat midbrain dopaminergic neurons. |
2002-06-27 |
2023-08-12 |
rat |
| Simonetta Prisco, Silvia Natoli, Giorgio Bernardi, Nicola B Mercur. Group I metabotropic glutamate receptors activate burst firing in rat midbrain dopaminergic neurons. Neuropharmacology. vol 42. issue 3. 2002-06-27. PMID:11897107. |
these results suggest that both the activation of glutamate metabotropic type 1 and nmda ionotropic receptors induce burst firing in the dopaminergic cells of the ventral midbrain when the activity of the sk-channels is reduced. |
2002-06-27 |
2023-08-12 |
rat |
| Bart A Ellenbroek, Luuk J Lubbers, Alexander R Cool. The role of hippocampal dopamine receptors in prepulse inhibition. The European journal of neuroscience. vol 15. issue 7. 2002-06-21. PMID:11982634. |
although it has long been realized that the hippocampal formation receives a projection from the midbrain dopaminergic cell groups and contains mrna for all five dopamine receptors, the functional role of this dopaminergic projection has not been studied so far. |
2002-06-21 |
2023-08-12 |
Not clear |
| T Gearan, O A Castillo, M A Schwarzschil. The parkinsonian neurotoxin, MPP+ induces phosphorylated c-Jun in dopaminergric neurons of mesencephalic cultures. Parkinsonism & related disorders. vol 8. issue 1. 2002-06-20. PMID:11472876. |
to assess the involvement of c-jun, a key transcription factor substrate of sapk (also known as c-jun n-terminal kinase, or jnk) in the mptp-induced death of dopaminergic nigral neurons, we determined the ability of mpp+, the active toxin metabolite of mptp, to induce the phosphorylated form of c-jun in dopaminergic neurons in nigral (ventral mesencephalon) cultures. |
2002-06-20 |
2023-08-12 |
Not clear |
| Paulo D Koeberle, Alexander K Bal. Neurturin enhances the survival of axotomized retinal ganglion cells in vivo: combined effects with glial cell line-derived neurotrophic factor and brain-derived neurotrophic factor. Neuroscience. vol 110. issue 3. 2002-06-12. PMID:11906793. |
the present findings have implications for the rescue of injured retinal ganglion cells, as well as other cns neurons that are responsive to neurturin, gdnf, and bdnf, including midbrain dopaminergic neurons and motor neurons. |
2002-06-12 |
2023-08-12 |
rat |