| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Ivanova, P Mendez, L M Garcia-Segura, C Beye. Rapid stimulation of the PI3-kinase/Akt signalling pathway in developing midbrain neurones by oestrogen. Journal of neuroendocrinology. vol 14. issue 1. 2002-05-02. PMID:11903815. |
in the rodent midbrain, the maturation of dopaminergic neurones appears to be under oestrogen control. |
2002-05-02 |
2023-08-12 |
mouse |
| Lee Anna Cunningham, Chunyan S. Astrocyte delivery of glial cell line-derived neurotrophic factor in a mouse model of Parkinson's disease. Experimental neurology. vol 174. issue 2. 2002-05-02. PMID:11922664. |
importantly, gdnf-producing astrocytes provided marked neuroprotection of nigral dopaminergic perikarya, and partial protection of striatal dopaminergic fibers, when implanted into the midbrain 6 days prior to a retrograde 6-ohda lesion, as assessed by tyrosine hydroxylase immunohistochemistry. |
2002-05-02 |
2023-08-12 |
mouse |
| N Thiriet, P Jouvert, S Gobaille, O Solov'eva, B Gough, D Aunis, S Ali, J Zwille. C-type natriuretic peptide (CNP) regulates cocaine-induced dopamine increase and immediate early gene expression in rat brain. The European journal of neuroscience. vol 14. issue 10. 2002-04-23. PMID:11860464. |
cnp may produce its effect directly on dopaminergic neurons because we found that its receptor, guanylyl cyclase gc-b, was expressed in the mesencephalon where dopaminergic neurons originate, as well as in their projection fields. |
2002-04-23 |
2023-08-12 |
rat |
| Akinori Akaike, Hiroshi Katsuki, Toshiaki Kum. [Role of nitric oxide in survival and death of neurons]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 119. issue 1. 2002-04-23. PMID:11862752. |
the prominent pathological feature of the brain in parkinson's disease is selective degeneration of dopaminergic neurons in the substantia nigra of the midbrain. |
2002-04-23 |
2023-08-12 |
Not clear |
| Akinori Akaike, Hiroshi Katsuki, Toshiaki Kum. [Role of nitric oxide in survival and death of neurons]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 119. issue 1. 2002-04-23. PMID:11862752. |
we further analyzed the change of resistance to excitotoxicity in midbrain dopaminergic neurons in co-culture with the striatum by using a slice culture technique. |
2002-04-23 |
2023-08-12 |
Not clear |
| Kerstin Krieglstein, Jens Strelau, Andreas Schober, Aideen Sullivan, Klaus Unsicke. TGF-beta and the regulation of neuron survival and death. Journal of physiology, Paris. vol 96. issue 1-2. 2002-04-16. PMID:11755780. |
gdf-15 is a potent trophic factor for developing and 6-ohda-lesioned midbrain dopaminergic neurons in vitro and in vivo, matching the potency of gdnf. |
2002-04-16 |
2023-08-12 |
Not clear |
| John P O'Doherty, Ralf Deichmann, Hugo D Critchley, Raymond J Dola. Neural responses during anticipation of a primary taste reward. Neuron. vol 33. issue 5. 2002-03-29. PMID:11879657. |
expectation of a pleasant taste produced activation in dopaminergic midbrain, posterior dorsal amygdala, striatum, and orbitofrontal cortex (ofc). |
2002-03-29 |
2023-08-12 |
human |
| C P Bailey, M J O'Callaghan, A P Croft, S J Manley, H J Littl. Alterations in mesolimbic dopamine function during the abstinence period following chronic ethanol consumption. Neuropharmacology. vol 41. issue 8. 2002-03-26. PMID:11747903. |
markedly reduced spontaneous firing rates of dopaminergic cells in the ventral tegmental area (vta) in midbrain slices were seen 6 days into the abstinence period after cessation of chronic ethanol consumption, but by 2 months the firing rates had returned to control values. |
2002-03-26 |
2023-08-12 |
Not clear |
| Y Nomur. Neurophysiology of Rett syndrome. Brain & development. vol 23 Suppl 1. 2002-03-13. PMID:11738842. |
psg revealed the brainstem and midbrain monoaminergic systems are deranged from early developmental stage, that is serotonin and noradrenaline systems seem to be hypoactive and dopaminergic system is also hypoactive associated with receptor supersensitivity. |
2002-03-13 |
2023-08-12 |
Not clear |
| Saga Johansson, Ingrid Strömber. Guidance of dopaminergic neuritic growth by immature astrocytes in organotypic cultures of rat fetal ventral mesencephalon. The Journal of comparative neurology. vol 443. issue 3. 2002-03-07. PMID:11807834. |
guidance of dopaminergic neuritic growth by immature astrocytes in organotypic cultures of rat fetal ventral mesencephalon. |
2002-03-07 |
2023-08-12 |
rat |
| Saga Johansson, Ingrid Strömber. Guidance of dopaminergic neuritic growth by immature astrocytes in organotypic cultures of rat fetal ventral mesencephalon. The Journal of comparative neurology. vol 443. issue 3. 2002-03-07. PMID:11807834. |
this study was performed to investigate astrocytic guidance of growth derived from dopaminergic neurons using organotypic cultures of rat fetal ventral mesencephalon. |
2002-03-07 |
2023-08-12 |
rat |
| Hiroshi Kawasaki, Hirofumi Suemori, Kenji Mizuseki, Kiichi Watanabe, Fumi Urano, Hiroshi Ichinose, Masatoshi Haruta, Masayo Takahashi, Kanako Yoshikawa, Shin-Ichi Nishikawa, Norio Nakatsuji, Yoshiki Sasa. Generation of dopaminergic neurons and pigmented epithelia from primate ES cells by stromal cell-derived inducing activity. Proceedings of the National Academy of Sciences of the United States of America. vol 99. issue 3. 2002-03-07. PMID:11818560. |
we previously identified a stromal cell-derived inducing activity (sdia), which induces differentiation of neural cells, including midbrain tyrosine hydroxylase-positive (th(+)) dopaminergic neurons, from mouse embryonic stem cells. |
2002-03-07 |
2023-08-12 |
mouse |
| Y H Chen, M T Tsai, C K Shaw, C H Che. Mutation analysis of the human NR4A2 gene, an essential gene for midbrain dopaminergic neurogenesis, in schizophrenic patients. American journal of medical genetics. vol 105. issue 8. 2002-03-05. PMID:11803525. |
mutation analysis of the human nr4a2 gene, an essential gene for midbrain dopaminergic neurogenesis, in schizophrenic patients. |
2002-03-05 |
2023-08-12 |
mouse |
| Y H Chen, M T Tsai, C K Shaw, C H Che. Mutation analysis of the human NR4A2 gene, an essential gene for midbrain dopaminergic neurogenesis, in schizophrenic patients. American journal of medical genetics. vol 105. issue 8. 2002-03-05. PMID:11803525. |
recent studies have revealed that an orphan receptor gene of the steroid/thyroid hormone nuclear receptor superfamily, the nurr1 gene, is essential for the neurogenesis and differentiation of dopaminergic neurons in the midbrain of mice. |
2002-03-05 |
2023-08-12 |
mouse |
| Y H Chen, M T Tsai, C K Shaw, C H Che. Mutation analysis of the human NR4A2 gene, an essential gene for midbrain dopaminergic neurogenesis, in schizophrenic patients. American journal of medical genetics. vol 105. issue 8. 2002-03-05. PMID:11803525. |
transgenic mice lacking the nurr1 gene soon die after birth and are devoid of dopaminergic neurons in the midbrain. |
2002-03-05 |
2023-08-12 |
mouse |
| Nandita Jha, M Jyothi Kumar, Rapee Boonplueang, Julie K Anderse. Glutathione decreases in dopaminergic PC12 cells interfere with the ubiquitin protein degradation pathway: relevance for Parkinson's disease? Journal of neurochemistry. vol 80. issue 4. 2002-03-04. PMID:11841562. |
parkinson's disease (pd) is characterized by the presence of proteinaceous neuronal inclusions called lewy bodies in susceptible dopaminergic midbrain neurons. |
2002-03-04 |
2023-08-12 |
Not clear |
| Hui-Ming Gao, Jau-Shyong Hong, Wanqin Zhang, Bin Li. Distinct role for microglia in rotenone-induced degeneration of dopaminergic neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 3. 2002-02-27. PMID:11826108. |
using primary neuron-enriched and neuron/glia cultures from the rat mesencephalon, we discovered an extraordinary feature for rotenone-induced degeneration of cultured dopaminergic neurons. |
2002-02-27 |
2023-08-12 |
rat |
| Henrike Neuhoff, Axel Neu, Birgit Liss, Jochen Roepe. I(h) channels contribute to the different functional properties of identified dopaminergic subpopulations in the midbrain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 4. 2002-02-26. PMID:11850457. |
i(h) channels contribute to the different functional properties of identified dopaminergic subpopulations in the midbrain. |
2002-02-26 |
2023-08-12 |
mouse |
| Henrike Neuhoff, Axel Neu, Birgit Liss, Jochen Roepe. I(h) channels contribute to the different functional properties of identified dopaminergic subpopulations in the midbrain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 4. 2002-02-26. PMID:11850457. |
dopaminergic (da) midbrain neurons in the substantia nigra (sn) and ventral tegmental area (vta) are involved in various brain functions such as voluntary movement and reward and are targets in disorders such as parkinson's disease and schizophrenia. |
2002-02-26 |
2023-08-12 |
mouse |
| V P Chekhonin, V P Baklaushev, O I Gurina, T B Dmitrieva, E A Savchenko, I P Lazarenko, S V Lebedev, V V Belopaso. Immunoenzyme assay of glial fibrillary acidic protein for evaluation of functional activity of cell grafts from embryonic ventral mesencephalon in rats with experimental hemiparkinsonism. Bulletin of experimental biology and medicine. vol 131. issue 6. 2002-02-14. PMID:11586404. |
it was found that intrastriatal transplantation of cell preparations from embryonic ventral mesencephalon significantly attenuated apomorphine-induced rotation, which points to functional recovery of the dopaminergic nigrostriatal system. |
2002-02-14 |
2023-08-12 |
rat |