| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kyoko Tsuboi, Clifford W Shult. Intrastriatal injection of sonic hedgehog reduces behavioral impairment in a rat model of Parkinson's disease. Experimental neurology. vol 173. issue 1. 2002-02-04. PMID:11771942. |
shh also promotes the survival of fetal dopaminergic neurons and protects cultures of fetal midbrain dopaminergic neurons from the toxic effects of n-methyl-4-phenylpyridinium (mpp(+)), a neurotoxin that selectively injures nigral dopaminergic neurons. |
2002-02-04 |
2023-08-12 |
human |
| S K Michelhaugh, C Fiskerstrand, E Lovejoy, M J Bannon, J P Quin. The dopamine transporter gene (SLC6A3) variable number of tandem repeats domain enhances transcription in dopamine neurons. Journal of neurochemistry. vol 79. issue 5. 2002-01-17. PMID:11739616. |
this study demonstrates by lipid transfection into an immortalized dopaminergic cell line and biolistic transfection into dopamine neurons in neonatal rat midbrain slices that the human nine-repeat dat vntr can enhance transcription. |
2002-01-17 |
2023-08-12 |
human |
| F Zheng, S W Johnso. Glycine receptor-mediated inhibition of dopamine and non-dopamine neurons of the rat ventral tegmental area in vitro. Brain research. vol 919. issue 2. 2002-01-15. PMID:11701143. |
dopaminergic and non-dopaminergic neurons of the ventral tegmental area (vta) were recorded intracellularly in slices of rat midbrain. |
2002-01-15 |
2023-08-12 |
rat |
| K Tanaka, T Suzuki, T Chiba, H Shimura, N Hattori, Y Mizun. Parkin is linked to the ubiquitin pathway. Journal of molecular medicine (Berlin, Germany). vol 79. issue 9. 2002-01-14. PMID:11692161. |
ar-jp is characterized by selective and massive loss of dopaminergic neurons in the substantia nigra of the midbrain and absence of lewy bodies, the pathological hallmark of idiopathic parkinson's disease. |
2002-01-14 |
2023-08-12 |
Not clear |
| A S Freeman, F K Weddige, J L Lipinsk. Effect of glucose on antipsychotic drug-induced changes in dopamine neuronal activity. European journal of pharmacology. vol 431. issue 1. 2002-01-11. PMID:11716841. |
the effect of glucose on antipsychotic drug-induced changes in the spontaneous activity of rat midbrain dopaminergic neurons was tested with the cells-per-track extracellular electrophysiology method. |
2002-01-11 |
2023-08-12 |
rat |
| A S Freeman, F K Weddige, J L Lipinsk. Effect of glucose on antipsychotic drug-induced changes in dopamine neuronal activity. European journal of pharmacology. vol 431. issue 1. 2002-01-11. PMID:11716841. |
these results suggest that caloric intake may influence antipsychotic drug-induced changes in the population activity of midbrain dopaminergic neurons. |
2002-01-11 |
2023-08-12 |
rat |
| F Amenta, F Mignini, A Ricci, M Sabbatini, D Tomassoni, S K Tayebat. Age-related changes of dopamine receptors in the rat hippocampus: a light microscope autoradiography study. Mechanisms of ageing and development. vol 122. issue 16. 2001-12-31. PMID:11589924. |
it is supplied with a dopaminergic innervation arising from the midbrain, which is part of the mesolimbic dopaminergic pathway. |
2001-12-31 |
2023-08-12 |
rat |
| D S Castro, E Hermanson, B Joseph, A Wallén, P Aarnisalo, A Heller, T Perlman. Induction of cell cycle arrest and morphological differentiation by Nurr1 and retinoids in dopamine MN9D cells. The Journal of biological chemistry. vol 276. issue 46. 2001-12-26. PMID:11553630. |
nurr1 is an orphan nuclear receptor essential for the development of midbrain dopaminergic neurons. |
2001-12-26 |
2023-08-12 |
Not clear |
| F Yang, L Feng, F Zheng, S W Johnson, J Du, L Shen, C P Wu, B L. GDNF acutely modulates excitability and A-type K(+) channels in midbrain dopaminergic neurons. Nature neuroscience. vol 4. issue 11. 2001-12-07. PMID:11593232. |
gdnf acutely modulates excitability and a-type k(+) channels in midbrain dopaminergic neurons. |
2001-12-07 |
2023-08-12 |
Not clear |
| F Yang, L Feng, F Zheng, S W Johnson, J Du, L Shen, C P Wu, B L. GDNF acutely modulates excitability and A-type K(+) channels in midbrain dopaminergic neurons. Nature neuroscience. vol 4. issue 11. 2001-12-07. PMID:11593232. |
glial cell line-derived neurotrophic factor (gdnf) prevents lesion-induced death of midbrain dopaminergic neurons, but its function in normal brain remains uncertain. |
2001-12-07 |
2023-08-12 |
Not clear |
| F Yang, L Feng, F Zheng, S W Johnson, J Du, L Shen, C P Wu, B L. GDNF acutely modulates excitability and A-type K(+) channels in midbrain dopaminergic neurons. Nature neuroscience. vol 4. issue 11. 2001-12-07. PMID:11593232. |
application of gdnf also elicited a map kinase-dependent enhancement of the excitability in dopaminergic neurons in midbrain slice. |
2001-12-07 |
2023-08-12 |
Not clear |
| F Yang, L Feng, F Zheng, S W Johnson, J Du, L Shen, C P Wu, B L. GDNF acutely modulates excitability and A-type K(+) channels in midbrain dopaminergic neurons. Nature neuroscience. vol 4. issue 11. 2001-12-07. PMID:11593232. |
these results demonstrate an acute regulation of gdnf on ion channels and its underlying signaling mechanism, and reveal an unexpected role of gdnf in normal midbrain dopaminergic neurons. |
2001-12-07 |
2023-08-12 |
Not clear |
| D Wirtshafter, A C Sheppar. Localization of GABA(B) receptors in midbrain monoamine containing neurons in the rat. Brain research bulletin. vol 56. issue 1. 2001-12-07. PMID:11604241. |
almost all of the serotonergic and dopaminergic cell bodies in the midbrain displayed gaba(b) receptor-like immunoreactivity. |
2001-12-07 |
2023-08-12 |
rat |
| K R Sidell, S J Olson, J J Ou, Y Zhang, V Amarnath, T J Montin. Cysteine and mercapturate conjugates of oxidized dopamine are in human striatum but only the cysteine conjugate impedes dopamine trafficking in vitro and in vivo. Journal of neurochemistry. vol 79. issue 3. 2001-12-07. PMID:11701754. |
here we investigated map enzymes and products in the midbrain and striatum of control individuals and patients with dementia with lewy bodies (dlb) who had less severe dopaminergic degeneration than pd patients and who were not treated with l-dopa. |
2001-12-07 |
2023-08-12 |
human |
| N Brunel, X J Wan. Effects of neuromodulation in a cortical network model of object working memory dominated by recurrent inhibition. Journal of computational neuroscience. vol 11. issue 1. 2001-12-04. PMID:11524578. |
these mechanisms could be implemented in the prefrontal cortex by dopaminergic projections from the midbrain. |
2001-12-04 |
2023-08-12 |
Not clear |
| E Küppers, T Ivanova, M Karolczak, N Lazarov, K Föhr, C Beye. Classical and nonclassical estrogen action in the developing midbrain. Hormones and behavior. vol 40. issue 2. 2001-12-04. PMID:11534982. |
in the midbrain, classical and nonclassical estrogen signaling routes operate side by side to ensure the proper development of dopaminergic cells. |
2001-12-04 |
2023-08-12 |
Not clear |
| B Liss, J Roepe. ATP-sensitive potassium channels in dopaminergic neurons: transducers of mitochondrial dysfunction. News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society. vol 16. 2001-12-04. PMID:11572924. |
dopaminergic midbrain neurons express alternative types of k(atp) channels mediating their differential response to mitochondrial complex i inhibition. |
2001-12-04 |
2023-08-12 |
Not clear |
| N Berretta, E Paolucci, G Bernardi, N B Mercur. Glutamate receptor stimulation induces a persistent rhythmicity of the GABAergic inputs to rat midbrain dopaminergic neurons. The European journal of neuroscience. vol 14. issue 5. 2001-12-04. PMID:11576181. |
glutamate receptor stimulation induces a persistent rhythmicity of the gabaergic inputs to rat midbrain dopaminergic neurons. |
2001-12-04 |
2023-08-12 |
rat |
| N Berretta, E Paolucci, G Bernardi, N B Mercur. Glutamate receptor stimulation induces a persistent rhythmicity of the GABAergic inputs to rat midbrain dopaminergic neurons. The European journal of neuroscience. vol 14. issue 5. 2001-12-04. PMID:11576181. |
here we report that in the dopaminergic neurons of the rat ventral midbrain a brief coactivation of group i metabotropic and nmda glutamate receptors may transform a temporally dispersed synaptic gabaergic input into a rhythmic pattern (range 4.5-22.5 hz), probably through a mechanism involving electrotonic couplings. |
2001-12-04 |
2023-08-12 |
rat |
| N Berretta, E Paolucci, G Bernardi, N B Mercur. Glutamate receptor stimulation induces a persistent rhythmicity of the GABAergic inputs to rat midbrain dopaminergic neurons. The European journal of neuroscience. vol 14. issue 5. 2001-12-04. PMID:11576181. |
the plastic and long-lasting modification in the temporal code of the inhibitory synaptic activity induced by glutamate may be a key element in determining the function of midbrain dopaminergic neurons in both normal and pathological behaviour. |
2001-12-04 |
2023-08-12 |
rat |