| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| N Matsuura, D C Lie, M Hoshimaru, M Asahi, M Hojo, R Ishizaki, N Hashimoto, S Noji, H Ohuchi, H Yoshioka, F H Gag. Sonic hedgehog facilitates dopamine differentiation in the presence of a mesencephalic glial cell line. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 12. 2001-07-12. PMID:11404418. |
this monoclonal, shh-n-overexpressing cell line further enhanced dopaminergic differentiation of e11 rat mesencephalon cells. |
2001-07-12 |
2023-08-12 |
rat |
| J Wolfart, H Neuhoff, O Franz, J Roepe. Differential expression of the small-conductance, calcium-activated potassium channel SK3 is critical for pacemaker control in dopaminergic midbrain neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 10. 2001-06-21. PMID:11331374. |
differential expression of the small-conductance, calcium-activated potassium channel sk3 is critical for pacemaker control in dopaminergic midbrain neurons. |
2001-06-21 |
2023-08-12 |
mouse |
| J Wolfart, H Neuhoff, O Franz, J Roepe. Differential expression of the small-conductance, calcium-activated potassium channel SK3 is critical for pacemaker control in dopaminergic midbrain neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 10. 2001-06-21. PMID:11331374. |
the physiological activity of dopaminergic midbrain (da) neurons is important for movement, cognition, and reward. |
2001-06-21 |
2023-08-12 |
mouse |
| K Sawamoto, N Nakao, K Kakishita, Y Ogawa, Y Toyama, A Yamamoto, M Yamaguchi, K Mori, S A Goldman, T Itakura, H Okan. Generation of dopaminergic neurons in the adult brain from mesencephalic precursor cells labeled with a nestin-GFP transgene. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 11. 2001-06-21. PMID:11356877. |
together, these findings indicate that precursor cells harvested from the embryonic ventral mesencephalon can generate dopaminergic neurons able to restore function to the chemically denervated adult striatum. |
2001-06-21 |
2023-08-12 |
mouse |
| H Katsuki, C Takenaka, T Kume, S Kaneko, A Akaik. Requirement of neural activity for the maintenance of dopaminergic neurons in rat midbrain slice cultures. Neuroscience letters. vol 300. issue 3. 2001-06-14. PMID:11226637. |
requirement of neural activity for the maintenance of dopaminergic neurons in rat midbrain slice cultures. |
2001-06-14 |
2023-08-12 |
rat |
| H Katsuki, C Takenaka, T Kume, S Kaneko, A Akaik. Requirement of neural activity for the maintenance of dopaminergic neurons in rat midbrain slice cultures. Neuroscience letters. vol 300. issue 3. 2001-06-14. PMID:11226637. |
chronic treatment of organotypic midbrain slice cultures with l-type ca(2+) channel blocker nicardipine (3-10 microm) or verapamil (10 microm) for 18 days resulted in a drastic decrease in the number of dopaminergic neurons. |
2001-06-14 |
2023-08-12 |
rat |
| H Katsuki, C Takenaka, T Kume, S Kaneko, A Akaik. Requirement of neural activity for the maintenance of dopaminergic neurons in rat midbrain slice cultures. Neuroscience letters. vol 300. issue 3. 2001-06-14. PMID:11226637. |
these results suggest that spontaneous neuronal activity within midbrain slice cultures, causing ca(2+) influx through l-type ca(2+) channels that maintains intracellular cyclic amp levels, is required for the maintenance of dopaminergic neurons. |
2001-06-14 |
2023-08-12 |
rat |
| M Rezgaoui, G Hermey, I B Riedel, W Hampe, H C Schaller, I Hermans-Borgmeye. Identification of SorCS2, a novel member of the VPS10 domain containing receptor family, prominently expressed in the developing mouse brain. Mechanisms of development. vol 100. issue 2. 2001-06-07. PMID:11165493. |
in addition, high transcript levels were detected transiently in a variety of brain regions including the dopaminergic midbrain nuclei and the dorsal thalamus. |
2001-06-07 |
2023-08-12 |
mouse |
| M Zarate-Lagunes, W J Gu, V Blanchard, C Francois, M P Muriel, A Mouatt-Prigent, B Bonici, A Parent, A Hartmann, J Yelnik, G A Boehme, L Pradier, S Moussaoui, B Faucheux, R Raisman-Vozari, Y Agid, A Brice, E C Hirsc. Parkin immunoreactivity in the brain of human and non-human primates: an immunohistochemical analysis in normal conditions and in Parkinsonian syndromes. The Journal of comparative neurology. vol 432. issue 2. 2001-06-07. PMID:11241385. |
it was detectable in the dopaminergic systems at the level of the perikarya in the mesencephalon but also in the striatum. |
2001-06-07 |
2023-08-12 |
human |
| H H Simon, H Saueressig, W Wurst, M D Goulding, D D O'Lear. Fate of midbrain dopaminergic neurons controlled by the engrailed genes. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 9. 2001-06-07. PMID:11312297. |
fate of midbrain dopaminergic neurons controlled by the engrailed genes. |
2001-06-07 |
2023-08-12 |
mouse |
| H H Simon, H Saueressig, W Wurst, M D Goulding, D D O'Lear. Fate of midbrain dopaminergic neurons controlled by the engrailed genes. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 9. 2001-06-07. PMID:11312297. |
deficiencies in neurotransmitter-specific cell groups in the midbrain result in prominent neural disorders, including parkinson's disease, which is caused by the loss of dopaminergic neurons of the substantia nigra. |
2001-06-07 |
2023-08-12 |
mouse |
| H H Simon, H Saueressig, W Wurst, M D Goulding, D D O'Lear. Fate of midbrain dopaminergic neurons controlled by the engrailed genes. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 9. 2001-06-07. PMID:11312297. |
we have investigated in mice the role of the engrailed homeodomain transcription factors, en-1 and en-2, in controlling the developmental fate of midbrain dopaminergic neurons. |
2001-06-07 |
2023-08-12 |
mouse |
| H H Simon, H Saueressig, W Wurst, M D Goulding, D D O'Lear. Fate of midbrain dopaminergic neurons controlled by the engrailed genes. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 9. 2001-06-07. PMID:11312297. |
these findings show that the engrailed genes are expressed by midbrain dopaminergic neurons from their generation to adulthood but are not required for their specification. |
2001-06-07 |
2023-08-12 |
mouse |
| H H Simon, H Saueressig, W Wurst, M D Goulding, D D O'Lear. Fate of midbrain dopaminergic neurons controlled by the engrailed genes. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 9. 2001-06-07. PMID:11312297. |
however, the engrailed genes control the survival of midbrain dopaminergic neurons in a gene dose-dependent manner. |
2001-06-07 |
2023-08-12 |
mouse |
| M Rodríguez, P Barroso-Chinea, P Abdala, J Obeso, T González-Hernánde. Dopamine cell degeneration induced by intraventricular administration of 6-hydroxydopamine in the rat: similarities with cell loss in parkinson's disease. Experimental neurology. vol 169. issue 1. 2001-06-07. PMID:11312569. |
in an attempt to find a convenient rat model to study cell vulnerability in parkinson's disease, we have investigated the cell-loss profile in different midbrain dopaminergic nuclei and subnuclei of rats injected with 6-hydroxydopamine (6-ohda) in the third ventricle. |
2001-06-07 |
2023-08-12 |
rat |
| A Snyder-Keller, L C Costantini, D J Grabe. Development of striatal patch/matrix organization in organotypic co-cultures of perinatal striatum, cortex and substantia nigra. Neuroscience. vol 103. issue 1. 2001-05-24. PMID:11311790. |
some were co-cultured with embryonic day 12-16 ventral mesencephalon and/or embryonic day 19 to postnatal day 4 cortex, which produced a dense dopaminergic innervation and a modest cortical innervation. |
2001-05-24 |
2023-08-12 |
rat |
| A Snyder-Keller, L C Costantini, D J Grabe. Development of striatal patch/matrix organization in organotypic co-cultures of perinatal striatum, cortex and substantia nigra. Neuroscience. vol 103. issue 1. 2001-05-24. PMID:11311790. |
furthermore, dopaminergic innervation from co-cultured pieces of ventral mesencephalon enhances patch formation in organotypic cultures. |
2001-05-24 |
2023-08-12 |
rat |
| G P Demyanenko, Y Shibata, P F Manes. Altered distribution of dopaminergic neurons in the brain of L1 null mice. Brain research. Developmental brain research. vol 126. issue 1. 2001-05-17. PMID:11172883. |
dopaminergic neurons of the mouse mesencephalon originate in the ventricular zone and migrate radially along radial glia then tangentially along nerve fibers that express the neural cell adhesion molecule l1 to form the substantia nigra (a9 group) and ventral tegmental area (vta) (a10 group). |
2001-05-17 |
2023-08-12 |
mouse |
| G P Demyanenko, Y Shibata, P F Manes. Altered distribution of dopaminergic neurons in the brain of L1 null mice. Brain research. Developmental brain research. vol 126. issue 1. 2001-05-17. PMID:11172883. |
these results suggested that l1 plays an important developmental role in the organization of dopaminergic neuronal cell groups in the mesencephalon and diencephalon. |
2001-05-17 |
2023-08-12 |
mouse |
| M Lebel, Y Gauthier, A Moreau, J Droui. Pitx3 activates mouse tyrosine hydroxylase promoter via a high-affinity binding site. Journal of neurochemistry. vol 77. issue 2. 2001-05-17. PMID:11299318. |
pitx3, a homeodomain-containing transcription factor, has been cloned from neuronal tissues and, in the cns, mouse pitx3 is exclusively expressed in midbrain dopaminergic (mesda) neurons from embryonic day 11 (e11). |
2001-05-17 |
2023-08-12 |
mouse |