| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J T Hong, K L Park, S Y Han, K S Park, H S Kim, S D Oh, R D Lee, S J Jan. Effects of ochratoxin A on cytotoxicity and cell differentiation in cultured rat embryonic cells. Journal of toxicology and environmental health. Part A. vol 61. issue 7. 2001-01-18. PMID:11127415. |
in the present study, the effects of ochratoxin a (ota) on cytotoxicity, cell differentiation, and other cell functions in the embryonic midbrain cells, which are dopaminergic, were compared to those in the limb bud cells, which are nondopaminergic, to assess the selectivity of ota central action. |
2001-01-18 |
2023-08-12 |
rat |
| L C Costantini, O Isacso. Neuroimmunophilin ligand enhances neurite outgrowth and effect of fetal dopamine transplants. Neuroscience. vol 100. issue 3. 2001-01-11. PMID:11098114. |
neuroimmunophilin ligands have been shown to enhance neurite outgrowth in several neuronal systems in culture, including primary dopaminergic neurons from fetal ventral mesencephalon. |
2001-01-11 |
2023-08-12 |
rat |
| C Flores, J Stewar. Basic fibroblast growth factor as a mediator of the effects of glutamate in the development of long-lasting sensitization to stimulant drugs: studies in the rat. Psychopharmacology. vol 151. issue 2-3. 2001-01-08. PMID:10972461. |
neuroadaptations initiated in the ventral tegmental area (vta), a cell body region of midbrain dopaminergic neurons, and dependent on glutamatergic transmission, underlie the development of this persistent drug-induced sensitization. |
2001-01-08 |
2023-08-12 |
rat |
| H Kawasaki, K Mizuseki, S Nishikawa, S Kaneko, Y Kuwana, S Nakanishi, S I Nishikawa, Y Sasa. Induction of midbrain dopaminergic neurons from ES cells by stromal cell-derived inducing activity. Neuron. vol 28. issue 1. 2000-12-22. PMID:11086981. |
induction of midbrain dopaminergic neurons from es cells by stromal cell-derived inducing activity. |
2000-12-22 |
2023-08-12 |
mouse |
| L S Kegeles, A Abi-Dargham, Y Zea-Ponce, J Rodenhiser-Hill, J J Mann, R L Van Heertum, T B Cooper, A Carlsson, M Laruell. Modulation of amphetamine-induced striatal dopamine release by ketamine in humans: implications for schizophrenia. Biological psychiatry. vol 48. issue 7. 2000-12-05. PMID:11032974. |
the activity of midbrain dopaminergic neurons is regulated, in part, by glutamatergic projections from the pfc acting via glutamatergic n-methyl-d-aspartate (nmda) receptors. |
2000-12-05 |
2023-08-12 |
Not clear |
| Z Y Han, N Le Novère, M Zoli, J A Hill, N Champtiaux, J P Changeu. Localization of nAChR subunit mRNAs in the brain of Macaca mulatta. The European journal of neuroscience. vol 12. issue 10. 2000-11-30. PMID:11029636. |
both alpha4 and beta2 mrna signals were widely distributed in the brain, being stronger in the thalamus and in the dopaminergic cells of the mesencephalon. |
2000-11-30 |
2023-08-12 |
human |
| S Ohmachi, Y Watanabe, T Mikami, N Kusu, T Ibi, A Akaike, N Ito. FGF-20, a novel neurotrophic factor, preferentially expressed in the substantia nigra pars compacta of rat brain. Biochemical and biophysical research communications. vol 277. issue 2. 2000-11-30. PMID:11032730. |
recombinant rat fgf-20 enhanced the survival of midbrain dopaminergic neurons. |
2000-11-30 |
2023-08-12 |
human |
| J Martí, K V Wills, B Ghetti, S A Baye. The weaver gene has no effect on the generation patterns of mesencephalic dopaminergic neurons. Brain research. Developmental brain research. vol 122. issue 2. 2000-11-13. PMID:10960685. |
both the span of neurogenesis and the neurogenetic timetables of dopaminergic neurons were similar between wild-type and homozygous weavers in all midbrain areas analyzed. |
2000-11-13 |
2023-08-12 |
mouse |
| J Martí, K V Wills, B Ghetti, S A Baye. The weaver gene has no effect on the generation patterns of mesencephalic dopaminergic neurons. Brain research. Developmental brain research. vol 122. issue 2. 2000-11-13. PMID:10960685. |
the cytoarchitecture of the midbrain dopaminergic cell groups were also the same in both experimental groups indicating that cell migration, settling, and cytodifferentiation proceeds normally in spite of the presence of the weaver gene. |
2000-11-13 |
2023-08-12 |
mouse |
| J Martí, K V Wills, B Ghetti, S A Baye. The weaver gene continues to target late-generated dopaminergic neurons in midbrain areas at P90. Brain research. Developmental brain research. vol 122. issue 2. 2000-11-13. PMID:10960686. |
the weaver gene continues to target late-generated dopaminergic neurons in midbrain areas at p90. |
2000-11-13 |
2023-08-12 |
mouse |
| J Martí, K V Wills, B Ghetti, S A Baye. The weaver gene continues to target late-generated dopaminergic neurons in midbrain areas at P90. Brain research. Developmental brain research. vol 122. issue 2. 2000-11-13. PMID:10960686. |
to determine if lethal action of the weaver gene is more intense in late-generated dopaminergic neurons in midbrain areas on postnatal day (p) 90 [3h] thymidine autoradiography and tyrosine hydroxylase immunohistochemistry were combined in the same tissue section in homozygous weaver mice and normal controls. |
2000-11-13 |
2023-08-12 |
mouse |
| J Martí, K V Wills, B Ghetti, S A Baye. The weaver gene continues to target late-generated dopaminergic neurons in midbrain areas at P90. Brain research. Developmental brain research. vol 122. issue 2. 2000-11-13. PMID:10960686. |
neurogenetic timetables of dopaminergic neurons were different between wild type and homozygous weavers in all midbrain areas analyzed. |
2000-11-13 |
2023-08-12 |
mouse |
| M Park, K Kitahama, M Geffard, T Maed. Postnatal development of the dopaminergic neurons in the rat mesencephalon. Brain & development. vol 22 Suppl 1. 2000-11-07. PMID:10984659. |
postnatal development of the dopaminergic neurons in the rat mesencephalon. |
2000-11-07 |
2023-08-12 |
rat |
| M J Bourque, L E Trudea. GDNF enhances the synaptic efficacy of dopaminergic neurons in culture. The European journal of neuroscience. vol 12. issue 9. 2000-11-07. PMID:10998101. |
glial cell line-derived neurotrophic factor (gdnf) is known to promote the survival and differentiation of dopaminergic neurons of the midbrain. |
2000-11-07 |
2023-08-12 |
rat |
| R I HogenEsch, J Koopmans, J C Copray, W M van Roon, I Kema, G Molenaar, K G Go, M J Staa. Fetal porcine ventral mesencephalon graft. Determination of the optimal gestational age for implantation in parkinsonian patients. Experimental brain research. vol 132. issue 3. 2000-10-19. PMID:10883382. |
human fetal ventral mesencephalon tissue has been used as dopaminergic striatal implants in parkinsonian patients, so far with variable effects. |
2000-10-19 |
2023-08-12 |
human |
| O Franz, B Liss, A Neu, J Roepe. Single-cell mRNA expression of HCN1 correlates with a fast gating phenotype of hyperpolarization-activated cyclic nucleotide-gated ion channels (Ih) in central neurons. The European journal of neuroscience. vol 12. issue 8. 2000-10-19. PMID:10971612. |
in contrast, hcn1 mrna was detected in neocortical and hippocampal pyramidal neurons but not in dopaminergic midbrain and thalamocortical neurons. |
2000-10-19 |
2023-08-12 |
mouse |
| N B Mercuri, M Federici, S Marinelli, G Bernard. Tranylcypromine, but not moclobemide, prolongs the inhibitory action of dopamine on midbrain dopaminergic neurons: an in vitro electrophysiological study. Synapse (New York, N.Y.). vol 37. issue 3. 2000-10-06. PMID:10881043. |
tranylcypromine, but not moclobemide, prolongs the inhibitory action of dopamine on midbrain dopaminergic neurons: an in vitro electrophysiological study. |
2000-10-06 |
2023-08-12 |
rat |
| N B Mercuri, M Federici, S Marinelli, G Bernard. Tranylcypromine, but not moclobemide, prolongs the inhibitory action of dopamine on midbrain dopaminergic neurons: an in vitro electrophysiological study. Synapse (New York, N.Y.). vol 37. issue 3. 2000-10-06. PMID:10881043. |
by using intracellular electrophysiological recordings, here we report that the irreversible mao a and b inhibitor tranylcypromine, but not the reversible mao a inhibitor moclobemide, potentiates da responses in rat midbrain dopaminergic neurones maintained in vitro. |
2000-10-06 |
2023-08-12 |
rat |
| B Franke, N Bayatti, J Engel. Neurotrophins require distinct extracellular signals to promote the survival of CNS neurons in vitro. Experimental neurology. vol 165. issue 1. 2000-10-04. PMID:10964491. |
in dissociated cell cultures of the embryonic rat mesencephalon, bdnf promoted dopaminergic cell survival only after a delay of several days. |
2000-10-04 |
2023-08-12 |
rat |
| M J Nowaczyk, M J Huggins, D J Tomkins, E Rossi, J A Ramsay, J Woulfe, S W Scherer, E Bellon. Holoprosencephaly, sacral anomalies, and situs ambiguus in an infant with partial monosomy 7q/trisomy 2p and SHH and HLXB9 haploinsufficiency.. Clinical genetics. vol 57. issue 5. 2000-09-28. PMID:10852374. |
immunohistochemical studies showed intact dopaminergic pathways in the mesencephalon, suggesting that midbrain dopamine neuron induction appears to require only one functioning shh allele. |
2000-09-28 |
2023-08-12 |
Not clear |