| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C Beyer, M Karolcza. Estrogenic stimulation of neurite growth in midbrain dopaminergic neurons depends on cAMP/protein kinase A signalling. Journal of neuroscience research. vol 59. issue 1. 2000-02-25. PMID:10658191. |
previous work from this laboratory indicates that the differentiation of mouse midbrain dopaminergic neurons is influenced by estrogen. |
2000-02-25 |
2023-08-12 |
mouse |
| C Beyer, M Karolcza. Estrogenic stimulation of neurite growth in midbrain dopaminergic neurons depends on cAMP/protein kinase A signalling. Journal of neuroscience research. vol 59. issue 1. 2000-02-25. PMID:10658191. |
in addition, estrogen exposure stimulated the phosphorylation of creb in midbrain dopaminergic cells as studied by quantitative double-labelling immunocytochemistry and gel shift assay. |
2000-02-25 |
2023-08-12 |
mouse |
| C Bäckman, T Perlmann, A Wallén, B J Hoffer, M Morale. A selective group of dopaminergic neurons express Nurr1 in the adult mouse brain. Brain research. vol 851. issue 1-2. 2000-02-24. PMID:10642835. |
recent analyses of nurr1 null mutant mice have shown that nurr1 is essential for the development and survival of midbrain dopaminergic neurons. |
2000-02-24 |
2023-08-12 |
mouse |
| C Bäckman, T Perlmann, A Wallén, B J Hoffer, M Morale. A selective group of dopaminergic neurons express Nurr1 in the adult mouse brain. Brain research. vol 851. issue 1-2. 2000-02-24. PMID:10642835. |
nurr1 expression was confined to periglomerular and midbrain dopaminergic neurons. |
2000-02-24 |
2023-08-12 |
mouse |
| C Bäckman, T Perlmann, A Wallén, B J Hoffer, M Morale. A selective group of dopaminergic neurons express Nurr1 in the adult mouse brain. Brain research. vol 851. issue 1-2. 2000-02-24. PMID:10642835. |
these results suggest that within the adult mouse brain, nurr1 may participate in dopaminergic functions of the olfactory bulb and midbrain. |
2000-02-24 |
2023-08-12 |
mouse |
| C A Murphy, L Ghazi, A Kokabi, G Elliso. Prenatal cocaine produces signs of neurodegeneration in the lateral habenula. Brain research. vol 851. issue 1-2. 2000-02-24. PMID:10642841. |
the lateral habenula is a nucleus in the dorsal thalamus that innervates midbrain dopaminergic and serotonergic nuclei via projections through its major efferent pathway, the fasciculus retroflexus (fr). |
2000-02-24 |
2023-08-12 |
rat |
| C Perrone-Capano, P Da Pozzo, U di Porzi. Epigenetic cues in midbrain dopaminergic neuron development. Neuroscience and biobehavioral reviews. vol 24. issue 1. 2000-02-17. PMID:10654667. |
midbrain dopaminergic (da) neurons subserve complex and varied neural functions in vertebrate cns. |
2000-02-17 |
2023-08-12 |
Not clear |
| V A Russel. The nucleus accumbens motor-limbic interface of the spontaneously hypertensive rat as studied in vitro by the superfusion slice technique. Neuroscience and biobehavioral reviews. vol 24. issue 1. 2000-02-17. PMID:10654669. |
the behavioral disturbances of attention-deficit hyperactivity disorder (adhd) have been attributed to dysfunction of the mesolimbic dopaminergic (da) projection from the ventral tegmental area of the midbrain. |
2000-02-17 |
2023-08-12 |
rat |
| H Katsuki, T Kume, S Kaneko, A Akaik. [Factors regulating survival and death of midbrain dopamine neurons]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 114 Suppl 1. 2000-02-16. PMID:10629879. |
we utilized organotypic midbrain slice cultures for the assessment of survival and degeneration of dopaminergic neurons in the substantia nigra. |
2000-02-16 |
2023-08-12 |
Not clear |
| H Katsuki, T Kume, S Kaneko, A Akaik. [Factors regulating survival and death of midbrain dopamine neurons]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 114 Suppl 1. 2000-02-16. PMID:10629879. |
application of n-methyl-d-aspartate (nmda) to midbrain slice cultures for 24 h caused a concentration-dependent decrease in the number of surviving dopaminergic neurons visualized by tyrosine hydroxylase immunohistochemistry. |
2000-02-16 |
2023-08-12 |
Not clear |
| H Katsuki, T Kume, S Kaneko, A Akaik. [Factors regulating survival and death of midbrain dopamine neurons]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 114 Suppl 1. 2000-02-16. PMID:10629879. |
we also prepared co-cultures of midbrain and striatal slices to investigate whether the presence of target tissue influences toxic actions of several drugs on dopaminergic neurons. |
2000-02-16 |
2023-08-12 |
Not clear |
| H Katsuki, T Kume, S Kaneko, A Akaik. [Factors regulating survival and death of midbrain dopamine neurons]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 114 Suppl 1. 2000-02-16. PMID:10629879. |
dopaminergic neurons in midbrain--striatum co-cultures were more resistant to the cytotoxic actions of nmda and a nitric oxide donor noc-18, than the same neuronal population in single midbrain cultures. |
2000-02-16 |
2023-08-12 |
Not clear |
| V Seutin, F Mkahli, L Massotte, A Dress. Calcium release from internal stores is required for the generation of spontaneous hyperpolarizations in dopaminergic neurons of neonatal rats. Journal of neurophysiology. vol 83. issue 1. 2000-02-16. PMID:10634866. |
we recently have demonstrated the existence of spontaneous hyperpolarizations in midbrain dopaminergic neurons of neonatal but not adult rats. |
2000-02-16 |
2023-08-12 |
rat |
| D M Donovan, L L Miner, M P Perry, R S Revay, L G Sharpe, S Przedborski, V Kostic, R M Philpot, C L Kirstein, R B Rothman, C W Schindler, G R Uh. Cocaine reward and MPTP toxicity: alteration by regional variant dopamine transporter overexpression. Brain research. Molecular brain research. vol 73. issue 1-2. 2000-02-14. PMID:10581396. |
the dopamine transporter (dat; slc6a3) is densely expressed by the dopaminergic midbrain neurons that play central roles in drug reward and is believed to be a primary site of action for cocaine reward. |
2000-02-14 |
2023-08-12 |
mouse |
| L Chen, D M Segal, C T Moraes, D C Mas. Dopamine transporter mRNA in autopsy studies of chronic cocaine users. Brain research. Molecular brain research. vol 73. issue 1-2. 2000-02-14. PMID:10581411. |
the effects of chronic cocaine abuse on transcriptional regulation of human dopamine transporter (dat) mrna in midbrain dopaminergic neurons was assessed by reverse transcription-polymerase chain reaction (rt-pcr). |
2000-02-14 |
2023-08-12 |
human |
| S R Sinclair, J W Fawcett, S B Dunnet. Dopamine cells in nigral grafts differentiate prior to implantation. The European journal of neuroscience. vol 11. issue 12. 2000-02-10. PMID:10594660. |
precursor cells that would differentiate into dopaminergic neurons beyond e14 if left in situ in the intact ventral mesencephalon do not readily differentiate into mature dopamine neurons following transplantation. |
2000-02-10 |
2023-08-12 |
rat |
| M Vila, S Vukosavic, V Jackson-Lewis, M Neystat, M Jakowec, S Przedborsk. Alpha-synuclein up-regulation in substantia nigra dopaminergic neurons following administration of the parkinsonian toxin MPTP. Journal of neurochemistry. vol 74. issue 2. 2000-02-10. PMID:10646524. |
after a regimen of mptp that kills dopaminergic neurons by apoptosis, synuclein mrna and protein levels were increased significantly in midbrain extracts; the time course of these changes paralleled that of mptp-induced dopaminergic neurodegeneration. |
2000-02-10 |
2023-08-12 |
mouse |
| B Gronier, K Rasmusse. Pertussis toxin treatment differentially affects cholinergic and dopaminergic receptor stimulation of midbrain dopaminergic neurons. Neuropharmacology. vol 38. issue 12. 2000-01-18. PMID:10608285. |
pertussis toxin treatment differentially affects cholinergic and dopaminergic receptor stimulation of midbrain dopaminergic neurons. |
2000-01-18 |
2023-08-12 |
rat |
| G S Kaminski Schierle, O Hansson, P Brundi. Flunarizine improves the survival of grafted dopaminergic neurons. Neuroscience. vol 94. issue 1. 2000-01-14. PMID:10613492. |
addition of 1 microm flunarizine inhibited cell death in a suspension of cells derived from the rat's ventral mesencephalon and when such a treated suspension was injected into the neostriatum there was a 2.6-fold greater number of surviving dopaminergic neurons, a doubling of the graft volume and a doubling of the volume of the host neostriatum innervated by dopaminergic fibers from the graft, compared with suspensions not exposed to flunarizine. |
2000-01-14 |
2023-08-12 |
rat |
| D C German, K F Manaye, D Wu, L B Hersh, R M Zwei. Mesopontine cholinergic and non-cholinergic neurons in schizophrenia. Neuroscience. vol 94. issue 1. 2000-01-14. PMID:10613494. |
mesopontine cholinergic neurons influence midbrain dopaminergic neurons, and thalamic and cerebellar structures which have been implicated in the neuroanatomy of schizophrenia. |
2000-01-14 |
2023-08-12 |
Not clear |