Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
H Sei, K Ikemoto, R Arai, Y Morit. Injection of 6-hydroxydopamine into the ventral tegmental area suppresses the increase in arterial pressure during REM sleep in the rat. Sleep research online : SRO. vol 2. issue 1. 2001-10-18. PMID:11382875. |
it is suggested that midbrain dopaminergic neurons are involved in the control of ap and hr during rem sleep and in the eeg theta activity. |
2001-10-18 |
2023-08-12 |
rat |
C B Hurelbrink, R J Armstrong, L M Luheshi, S B Dunnett, A E Rosser, R A Barke. Death of dopaminergic neurons in vitro and in nigral grafts: reevaluating the role of caspase activation. Experimental neurology. vol 171. issue 1. 2001-10-11. PMID:11520120. |
in this study, the role of caspase-1 and -3 in the death of dopaminergic neurons derived from the e14 rat ventral mesencephalon (vm) has been examined in two model systems using peptide caspase inhibitors. |
2001-10-11 |
2023-08-12 |
rat |
L Zaborszky, C Vadas. The midbrain dopaminergic system: anatomy and genetic variation in dopamine neuron number of inbred mouse strains. Behavior genetics. vol 31. issue 1. 2001-10-11. PMID:11529274. |
the midbrain dopaminergic system: anatomy and genetic variation in dopamine neuron number of inbred mouse strains. |
2001-10-11 |
2023-08-12 |
mouse |
D SiuYi Leung, K Unsicker, B Reus. Gap junctions modulate survival-promoting effects of fibroblast growth factor-2 on cultured midbrain dopaminergic neurons. Molecular and cellular neurosciences. vol 18. issue 1. 2001-09-27. PMID:11461152. |
gap junctions modulate survival-promoting effects of fibroblast growth factor-2 on cultured midbrain dopaminergic neurons. |
2001-09-27 |
2023-08-12 |
rat |
D SiuYi Leung, K Unsicker, B Reus. Gap junctions modulate survival-promoting effects of fibroblast growth factor-2 on cultured midbrain dopaminergic neurons. Molecular and cellular neurosciences. vol 18. issue 1. 2001-09-27. PMID:11461152. |
fibroblast growth factor 2 (fgf-2) and glial cell line-derived neurotrophic factor (gdnf) support survival of dopaminergic midbrain neurons. |
2001-09-27 |
2023-08-12 |
rat |
D SiuYi Leung, K Unsicker, B Reus. Gap junctions modulate survival-promoting effects of fibroblast growth factor-2 on cultured midbrain dopaminergic neurons. Molecular and cellular neurosciences. vol 18. issue 1. 2001-09-27. PMID:11461152. |
furthermore, the gap junction blocker oleamide abolished survival-promoting effects of fgf-2 on dopaminergic midbrain neurons. |
2001-09-27 |
2023-08-12 |
rat |
D SiuYi Leung, K Unsicker, B Reus. Gap junctions modulate survival-promoting effects of fibroblast growth factor-2 on cultured midbrain dopaminergic neurons. Molecular and cellular neurosciences. vol 18. issue 1. 2001-09-27. PMID:11461152. |
together, these results support a direct role of gap junction communication for survival-promoting effects of fgf-2 on dopaminergic midbrain neurons, making gap junction communication a substantial parameter for neuron survival. |
2001-09-27 |
2023-08-12 |
rat |
V M Goettl, T A Wemlinger, A E Colvin, N H Neff, M Hadjiconstantino. Motoric behavior in aged rats treated with GM1. Brain research. vol 906. issue 1-2. 2001-09-13. PMID:11430865. |
gm1 ganglioside partially restores pre-synaptic dopaminergic markers and the number and morphology of dopaminergic neurons in the midbrain and striatum of sprague--dawley aged rats. |
2001-09-13 |
2023-08-12 |
rat |
W Chen, S Burgess, N Hopkin. Analysis of the zebrafish smoothened mutant reveals conserved and divergent functions of hedgehog activity. Development (Cambridge, England). vol 128. issue 12. 2001-09-13. PMID:11493557. |
interestingly, even after inhibition of maternal hedgehog activity, the midbrain dopaminergic neurons still form, and looping of the heart does not randomize in the mutants. |
2001-09-13 |
2023-08-12 |
drosophila_melanogaster |
B Liu, L Qin, S N Yang, B C Wilson, Y Liu, J S Hon. Femtomolar concentrations of dynorphins protect rat mesencephalic dopaminergic neurons against inflammatory damage. The Journal of pharmacology and experimental therapeutics. vol 298. issue 3. 2001-09-13. PMID:11504811. |
the purpose of this study was to explore the neuroprotective effect of dynorphins in the inflammation-mediated degeneration of dopaminergic neurons in rat midbrain neuron-glia cultures. |
2001-09-13 |
2023-08-12 |
rat |
T Brevig, M Meyer, T Kristensen, J Zimme. Neural xenotransplantation: pretreatment of porcine embryonic nigral tissue with anti-Gal antibodies and complement is not toxic for the dopaminergic neurons. Cell transplantation. vol 10. issue 1. 2001-08-16. PMID:11294468. |
in the present study, our aim was to determine whether a pretreatment with antibodies against the alpha-galactosyl epitope (anti-gal) and complement would lyse or otherwise damage dopaminergic neurons in porcine embryonic ventral mesencephalon (vm), the donor tissue for treatment of parkinson's disease by xenotransplantation. |
2001-08-16 |
2023-08-12 |
human |
V P Chekhonin, V P Baklaushev, T B Dmitrieva, B M Kogan, E A Savchenko, S V Lebedev, I P Lazarenko, I V Man'kovskaya, T S Filatova, V V Belopaso. Complex analysis of efficiency of transplantation of embryonic nerve tissue to rats with hemiparkinsonism. Bulletin of experimental biology and medicine. vol 130. issue 12. 2001-08-02. PMID:11276317. |
effect of transplantation of embryonic ventral mesencephalon preparation containing dopaminergic neurons on repair of the dopaminergic nigrostriatal system was studied in rats with hemiparkinsonism induced by 6-hydroxydopamine. |
2001-08-02 |
2023-08-12 |
rat |
M Cassidy, P Brow. Task-related EEG-EEG coherence depends on dopaminergic activity in Parkinson's disease. Neuroreport. vol 12. issue 4. 2001-08-02. PMID:11277568. |
ascending dopaminergic projections from the ventral mesencephalon may therefore be important in determining the pattern and extent of corticocortical coupling during executive tasks. |
2001-08-02 |
2023-08-12 |
Not clear |
X Guo, V L Dawson, T M Dawso. Neuroimmunophilin ligands exert neuroregeneration and neuroprotection in midbrain dopaminergic neurons. The European journal of neuroscience. vol 13. issue 9. 2001-07-26. PMID:11359520. |
neuroimmunophilin ligands exert neuroregeneration and neuroprotection in midbrain dopaminergic neurons. |
2001-07-26 |
2023-08-12 |
mouse |
X Guo, V L Dawson, T M Dawso. Neuroimmunophilin ligands exert neuroregeneration and neuroprotection in midbrain dopaminergic neurons. The European journal of neuroscience. vol 13. issue 9. 2001-07-26. PMID:11359520. |
in the present study, we use mpp+ and 6-ohda toxicity models to examine both neuroprotective and neuroregenerative effects of immunophilin ligands on primary cultures of midbrain dopaminergic neurons. |
2001-07-26 |
2023-08-12 |
mouse |
J D Adams, M L Chang, L Klaidma. Parkinson's disease--redox mechanisms. Current medicinal chemistry. vol 8. issue 7. 2001-07-26. PMID:11375751. |
parkinson's disease occurs in 1% of people over the age of 65 when about 60% of the dopaminergic neurons in the substantia nigra of the midbrain are lost. |
2001-07-26 |
2023-08-12 |
Not clear |
E Küppers, T Ivanova, M Karolczak, C Beye. Estrogen: a multifunctional messenger to nigrostriatal dopaminergic neurons. Journal of neurocytology. vol 29. issue 5-6. 2001-07-26. PMID:11424954. |
in the past, we have intensively studied the effects of estrogen on midbrain dopaminergic neurons which represent the most affected cell population during parkinson's disease. |
2001-07-26 |
2023-08-12 |
Not clear |
J B Eells, J E Rives, S K Yeung, V M Nikode. In vitro regulated expression of tyrosine hydroxylase in ventral midbrain neurons from Nurr1-null mouse pups. Journal of neuroscience research. vol 64. issue 4. 2001-07-19. PMID:11340638. |
the transcription factor nurr1, an orphan member of the steroid-thyroid hormone nuclear receptor superfamily, is essential for the proper terminal differentiation of ventral midbrain dopaminergic neurons. |
2001-07-19 |
2023-08-12 |
mouse |
K Sawamoto, N Nakao, K Kobayashi, N Matsushita, H Takahashi, K Kakishita, A Yamamoto, T Yoshizaki, T Terashima, F Murakami, T Itakura, H Okan. Visualization, direct isolation, and transplantation of midbrain dopaminergic neurons. Proceedings of the National Academy of Sciences of the United States of America. vol 98. issue 11. 2001-07-19. PMID:11353855. |
visualization, direct isolation, and transplantation of midbrain dopaminergic neurons. |
2001-07-19 |
2023-08-12 |
mouse |
S R Laviolette, D van der Koo. GABA(A) receptors in the ventral tegmental area control bidirectional reward signalling between dopaminergic and non-dopaminergic neural motivational systems. The European journal of neuroscience. vol 13. issue 5. 2001-07-12. PMID:11264674. |
in the midbrain ventral tegmental area (vta), both dopaminergic and nondopaminergic neural substrates mediate various behavioural reward phenomena. |
2001-07-12 |
2023-08-12 |
Not clear |