| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Gille, W-D Rausch, S-T Hung, R Moldzio, B Janetzky, H P Hundemer, T Kolter, H Reichman. Pergolide protects dopaminergic neurons in primary culture under stress conditions. Journal of neural transmission (Vienna, Austria : 1996). vol 109. issue 5-6. 2002-08-06. PMID:12111455. |
in primary cultures from mouse mesencephalon we show that pergolide, a preferential d(2) agonist enhanced the survival of healthy dopaminergic neurons at low concentrations of 0.001 microm. |
2002-08-06 |
2023-08-12 |
mouse |
| K Kitahama, A Jouvet, M Fujimiya, I Nagatsu, R Ara. 5-Hydroxytryptophan (5-HTP) uptake and decarboxylation in the kitten brain. Journal of neural transmission (Vienna, Austria : 1996). vol 109. issue 5-6. 2002-08-06. PMID:12111460. |
after loading of 5-htp and monoamine oxidase inhibitor (maoi), we could demonstrate 5-ht-immunoreactivity (ir) not only in hypothalamic and midbrain dopaminergic (da) cell bodies, but also in na ones located in the pons and medulla oblongata of the new born kitten aged from 1 to 7 days. |
2002-08-06 |
2023-08-12 |
Not clear |
| Seiji Nishino, Beth Ripley, Emmanuel Mignot, Kathleen L Benson, Vincent P Zarcon. CSF hypocretin-1 levels in schizophrenics and controls: relationship to sleep architecture. Psychiatry research. vol 110. issue 1. 2002-07-31. PMID:12007588. |
hypocretin is known to excite midbrain dopaminergic neurons and to induce hyperactivity and stereotypy in animals. |
2002-07-31 |
2023-08-12 |
human |
| Anh Hai Tran, Ryoi Tamura, Teruko Uwano, Tsuneyuki Kobayashi, Motoya Katsuki, Gen Matsumoto, Taketoshi On. Altered accumbens neural response to prediction of reward associated with place in dopamine D2 receptor knockout mice. Proceedings of the National Academy of Sciences of the United States of America. vol 99. issue 13. 2002-07-19. PMID:12084937. |
midbrain dopaminergic activity seems to be important in forming the prediction of future events such as rewards. |
2002-07-19 |
2023-08-12 |
mouse |
| François Georges, Gary Aston-Jone. Activation of ventral tegmental area cells by the bed nucleus of the stria terminalis: a novel excitatory amino acid input to midbrain dopamine neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 12. 2002-07-15. PMID:12077212. |
we examined the role of excitatory amino acids (eaas) in the activation of midbrain dopaminergic (da) neurons evoked by stimulation of the ventromedial and ventrolateral (subcommissural) bed nucleus of the stria terminalis (vbnst). |
2002-07-15 |
2023-08-12 |
rat |
| Long Ding, David J Perke. Dopamine modulates excitability of spiny neurons in the avian basal ganglia. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 12. 2002-07-15. PMID:12077216. |
like their mammalian counterparts, they receive dense dopaminergic innervation from the midbrain, but the physiological functions of this projection remain unclear. |
2002-07-15 |
2023-08-12 |
Not clear |
| M Yoshimura, T Yamamoto, N Iso-o, I Imafuku, T Momose, I Shirouzu, S Kwak, I Kanazaw. Hemiparkinsonism associated with a mesencephalic tumor. Journal of the neurological sciences. vol 197. issue 1-2. 2002-07-03. PMID:11997073. |
these findings are consistent with a dysfunction in the left nigrostriatal dopaminergic pathway that is presumably induced by the cystic mass in the left midbrain. |
2002-07-03 |
2023-08-12 |
Not clear |
| Simonetta Prisco, Silvia Natoli, Giorgio Bernardi, Nicola B Mercur. Group I metabotropic glutamate receptors activate burst firing in rat midbrain dopaminergic neurons. Neuropharmacology. vol 42. issue 3. 2002-06-27. PMID:11897107. |
group i metabotropic glutamate receptors activate burst firing in rat midbrain dopaminergic neurons. |
2002-06-27 |
2023-08-12 |
rat |
| Simonetta Prisco, Silvia Natoli, Giorgio Bernardi, Nicola B Mercur. Group I metabotropic glutamate receptors activate burst firing in rat midbrain dopaminergic neurons. Neuropharmacology. vol 42. issue 3. 2002-06-27. PMID:11897107. |
these results suggest that both the activation of glutamate metabotropic type 1 and nmda ionotropic receptors induce burst firing in the dopaminergic cells of the ventral midbrain when the activity of the sk-channels is reduced. |
2002-06-27 |
2023-08-12 |
rat |
| Bart A Ellenbroek, Luuk J Lubbers, Alexander R Cool. The role of hippocampal dopamine receptors in prepulse inhibition. The European journal of neuroscience. vol 15. issue 7. 2002-06-21. PMID:11982634. |
although it has long been realized that the hippocampal formation receives a projection from the midbrain dopaminergic cell groups and contains mrna for all five dopamine receptors, the functional role of this dopaminergic projection has not been studied so far. |
2002-06-21 |
2023-08-12 |
Not clear |
| T Gearan, O A Castillo, M A Schwarzschil. The parkinsonian neurotoxin, MPP+ induces phosphorylated c-Jun in dopaminergric neurons of mesencephalic cultures. Parkinsonism & related disorders. vol 8. issue 1. 2002-06-20. PMID:11472876. |
to assess the involvement of c-jun, a key transcription factor substrate of sapk (also known as c-jun n-terminal kinase, or jnk) in the mptp-induced death of dopaminergic nigral neurons, we determined the ability of mpp+, the active toxin metabolite of mptp, to induce the phosphorylated form of c-jun in dopaminergic neurons in nigral (ventral mesencephalon) cultures. |
2002-06-20 |
2023-08-12 |
Not clear |
| Paulo D Koeberle, Alexander K Bal. Neurturin enhances the survival of axotomized retinal ganglion cells in vivo: combined effects with glial cell line-derived neurotrophic factor and brain-derived neurotrophic factor. Neuroscience. vol 110. issue 3. 2002-06-12. PMID:11906793. |
the present findings have implications for the rescue of injured retinal ganglion cells, as well as other cns neurons that are responsive to neurturin, gdnf, and bdnf, including midbrain dopaminergic neurons and motor neurons. |
2002-06-12 |
2023-08-12 |
rat |
| Yoshiko Nomur. [Pathophysiology of Rett syndrome from the standpoints of clinical characteristics and clinical neurophysiological findings]. No to hattatsu = Brain and development. vol 34. issue 3. 2002-05-31. PMID:12030007. |
psg suggested the early dysfunction of the brainstem and midbrain monoaminergic systems; hypoactive serotonin and noradrenaline systems and dopaminergic system associated with receptor supersensitivity. |
2002-05-31 |
2023-08-12 |
Not clear |
| L M Farkas, K Krieglstei. Heparin-binding epidermal growth factor-like growth factor (HB-EGF) regulates survival of midbrain dopaminergic neurons. Journal of neural transmission (Vienna, Austria : 1996). vol 109. issue 3. 2002-05-23. PMID:11956950. |
heparin-binding epidermal growth factor-like growth factor (hb-egf) regulates survival of midbrain dopaminergic neurons. |
2002-05-23 |
2023-08-12 |
Not clear |
| L M Farkas, K Krieglstei. Heparin-binding epidermal growth factor-like growth factor (HB-EGF) regulates survival of midbrain dopaminergic neurons. Journal of neural transmission (Vienna, Austria : 1996). vol 109. issue 3. 2002-05-23. PMID:11956950. |
these findings indicate that hb-egf may be an important molecule for developing dopaminergic neurons of the ventral midbrain. |
2002-05-23 |
2023-08-12 |
Not clear |
| José L Venero, El-Hadi Absi, Josefina Cano, Alberto Machad. Melatonin induces tyrosine hydroxylase mRNA expression in the ventral mesencephalon but not in the hypothalamus. Journal of pineal research. vol 32. issue 1. 2002-05-20. PMID:11841594. |
in the ventral mesencephalon, melatonin treatment significantly induced th mrna levels in individual dopaminergic neurons in sn and vta. |
2002-05-20 |
2023-08-12 |
rat |
| Xue-June Li, Jing Gu, Shi-Duo Lu, Feng-Yan Su. Melatonin attenuates MPTP-induced dopaminergic neuronal injury associated with scavenging hydroxyl radical. Journal of pineal research. vol 32. issue 1. 2002-05-20. PMID:11841600. |
however, melatonin dose-dependently inhibited the increase of dhba levels in ventral midbrain tissues, the decrease of da content and the loss of dopaminergic neurons. |
2002-05-20 |
2023-08-12 |
mouse |
| Anton Reine. Functional circuitry of the avian basal ganglia: implications for basal ganglia organization in stem amniotes. Brain research bulletin. vol 57. issue 3-4. 2002-05-20. PMID:11923021. |
these include: (1) an extensive glutamatergic "cortico"-striatal input and distinctive, cell-type specific localization of glutamate receptor subtypes; (2) an extensive, presumptively glutamatergic intralaminar thalamic input to striatal neurons; (3) an extensive dopaminergic input from the midbrain targeting both substance p (sp) type and enkephalin (enk) type striatal projection neurons, with sp-type striatal neurons seemingly richer in the d-1 type dopamine receptor; and (4) sp+ and enk+ striatal outputs giving rise to functionally distinct so-called direct and indirect motor output pathways, with the direct pathway having a pallido-thalamo-motor cortex loop and the indirect pathway relaying back to the direct circuit via the subthalamic nucleus. |
2002-05-20 |
2023-08-12 |
Not clear |
| Jakob Wolfart, Jochen Roepe. Selective coupling of T-type calcium channels to SK potassium channels prevents intrinsic bursting in dopaminergic midbrain neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 9. 2002-05-20. PMID:11978817. |
selective coupling of t-type calcium channels to sk potassium channels prevents intrinsic bursting in dopaminergic midbrain neurons. |
2002-05-20 |
2023-08-12 |
Not clear |
| Jakob Wolfart, Jochen Roepe. Selective coupling of T-type calcium channels to SK potassium channels prevents intrinsic bursting in dopaminergic midbrain neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 9. 2002-05-20. PMID:11978817. |
dopaminergic midbrain (da) neurons display two principal activity patterns in vivo, single-spike and burst firing, the latter coding for reward-related events. |
2002-05-20 |
2023-08-12 |
Not clear |