| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Piia Aarnisalo, Chae-Hee Kim, Jae Woon Lee, Thomas Perlman. Defining requirements for heterodimerization between the retinoid X receptor and the orphan nuclear receptor Nurr1. The Journal of biological chemistry. vol 277. issue 38. 2002-10-24. PMID:12130634. |
nurr1, an orphan nuclear receptor mainly expressed in the central nervous system, is essential for the development of the midbrain dopaminergic neurons. |
2002-10-24 |
2023-08-12 |
Not clear |
| Srinivas Bharath, Michael Hsu, Deepinder Kaur, Subramanian Rajagopalan, Julie K Anderse. Glutathione, iron and Parkinson's disease. Biochemical pharmacology. vol 64. issue 5-6. 2002-10-17. PMID:12213603. |
parkinson's disease (pd) is a progressive neurodegenerative disease involving neurodegeneration of dopaminergic neurons of the substantia nigra (sn), a part of the midbrain. |
2002-10-17 |
2023-08-12 |
Not clear |
| Bassem F El-Khodor, Robert E Burk. Medial forebrain bundle axotomy during development induces apoptosis in dopamine neurons of the substantia nigra and activation of caspases in their degenerating axons. The Journal of comparative neurology. vol 452. issue 1. 2002-10-16. PMID:12205710. |
we find that this lesion induces apoptosis in midbrain dopaminergic neurons at the level of the cell soma. |
2002-10-16 |
2023-08-12 |
Not clear |
| Yaping Chu, Katie Kompoliti, Elizabeth J Cochran, Elliott J Mufson, Jeffrey H Kordowe. Age-related decreases in Nurr1 immunoreactivity in the human substantia nigra. The Journal of comparative neurology. vol 450. issue 3. 2002-10-10. PMID:12209851. |
nuclear receptor-related factor 1 (nurr1), a member of the nuclear receptor superfamily, is associated with the induction of dopaminergic (da) phenotypes in developing and mature midbrain neurons. |
2002-10-10 |
2023-08-12 |
human |
| Joaquín Martí, Katherine V Wills, Bernardino Ghetti, Shirley A Baye. A combined immunohistochemical and autoradiographic method to detect midbrain dopaminergic neurons and determine their time of origin. Brain research. Brain research protocols. vol 9. issue 3. 2002-09-27. PMID:12113779. |
a combined immunohistochemical and autoradiographic method to detect midbrain dopaminergic neurons and determine their time of origin. |
2002-09-27 |
2023-08-12 |
mouse |
| Joaquín Martí, Katherine V Wills, Bernardino Ghetti, Shirley A Baye. A combined immunohistochemical and autoradiographic method to detect midbrain dopaminergic neurons and determine their time of origin. Brain research. Brain research protocols. vol 9. issue 3. 2002-09-27. PMID:12113779. |
the method described here allows us to demonstrate that the neurogenetic timetables of midbrain dopaminergic neurons were different between control and homozygous weaver mice in the mesencephalic area studied. |
2002-09-27 |
2023-08-12 |
mouse |
| Mauro Federici, Silvia Natoli, Giorgio Bernardi, Nicola B Mercur. Dopamine selectively reduces GABA(B) transmission onto dopaminergic neurones by an unconventional presynaptic action. The Journal of physiology. vol 540. issue Pt 1. 2002-09-23. PMID:11927674. |
the functioning of midbrain dopaminergic neurones is closely involved in mental processes and movement. |
2002-09-23 |
2023-08-12 |
Not clear |
| Virginia M Pickel, Miguel Garzón, Elisa Mengua. Electron microscopic immunolabeling of transporters and receptors identifies transmitter-specific functional sites envisioned in Cajal's neuron. Progress in brain research. vol 136. 2002-09-19. PMID:12143378. |
dopamine terminals in the striatum and ventral pallidum, as well as dendrites of midbrain dopaminergic neurons in the ventral tegmental area and substantia nigra express the plasmalemmal dopamine transporter (dat) and the vesicular monoamine transporter (vmat2). |
2002-09-19 |
2023-08-12 |
Not clear |
| Virginia M Pickel, Miguel Garzón, Elisa Mengua. Electron microscopic immunolabeling of transporters and receptors identifies transmitter-specific functional sites envisioned in Cajal's neuron. Progress in brain research. vol 136. 2002-09-19. PMID:12143378. |
in somata and dendrites of the midbrain dopaminergic neurons, d2r labeling is expressed in most dendrites that contain vmat2 storage vesicles, as well as in both excitatory and inhibitory afferents. |
2002-09-19 |
2023-08-12 |
Not clear |
| Jacqueline Scuvee-Moreau, Jean-François Liegeois, Laurent Massotte, Vincent Seuti. Methyl-laudanosine: a new pharmacological tool to investigate the function of small-conductance Ca(2+)-activated K(+) channels. The Journal of pharmacology and experimental therapeutics. vol 302. issue 3. 2002-09-18. PMID:12183678. |
intracellular recordings were performed on rat midbrain dopaminergic neurons and hippocampus ca1 pyramidal cells. |
2002-09-18 |
2023-08-12 |
rat |
| Michelle Smeyne, Richard J Smeyn. Method for culturing postnatal substantia nigra as an in vitro model of experimental Parkinson's disease. Brain research. Brain research protocols. vol 9. issue 2. 2002-09-10. PMID:12034329. |
by specifically culturing ventrolateral midbrain containing the substantia nigra, one can more directly target the effects of dopaminergic toxins. |
2002-09-10 |
2023-08-12 |
Not clear |
| Szilvia Mezey, András Csilla. Selective striatal connections of midbrain dopaminergic nuclei in the chick (Gallus domesticus). Cell and tissue research. vol 308. issue 1. 2002-09-06. PMID:12012204. |
selective striatal connections of midbrain dopaminergic nuclei in the chick (gallus domesticus). |
2002-09-06 |
2023-08-12 |
chicken |
| Diego Centonze, Enrico Bracci, Antonio Pisani, Paolo Gubellini, Giorgio Bernardi, Paolo Calabres. Activation of dopamine D1-like receptors excites LTS interneurons of the striatum. The European journal of neuroscience. vol 15. issue 12. 2002-09-04. PMID:12099911. |
along with projection cells, striatal interneurons receive dense dopaminergic innervation from midbrain neurons, thus, also suggesting that these intrinsic cells represent a synaptic target for da action in the striatum. |
2002-09-04 |
2023-08-12 |
rat |
| D Chichung Lie, Gustavo Dziewczapolski, Andrew R Willhoite, Brian K Kaspar, Clifford W Shults, Fred H Gag. The adult substantia nigra contains progenitor cells with neurogenic potential. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 15. 2002-09-03. PMID:12151543. |
one current therapy aims at exogenous cellular replacement of dopaminergic function by transplanting fetal midbrain cells into the striatum, the main projection area of the sn. |
2002-09-03 |
2023-08-12 |
Not clear |
| Samina S Riaz, Eric Jauniaux, Gerald M Stern, Henry F Bradfor. The controlled conversion of human neural progenitor cells derived from foetal ventral mesencephalon into dopaminergic neurons in vitro. Brain research. Developmental brain research. vol 136. issue 1. 2002-08-27. PMID:12036514. |
the controlled conversion of human neural progenitor cells derived from foetal ventral mesencephalon into dopaminergic neurons in vitro. |
2002-08-27 |
2023-08-12 |
human |
| Samina S Riaz, Eric Jauniaux, Gerald M Stern, Henry F Bradfor. The controlled conversion of human neural progenitor cells derived from foetal ventral mesencephalon into dopaminergic neurons in vitro. Brain research. Developmental brain research. vol 136. issue 1. 2002-08-27. PMID:12036514. |
here, the controlled conversion of human foetal progenitor cells derived from ventral mesencephalon into dopaminergic neurons is reported. |
2002-08-27 |
2023-08-12 |
human |
| Andreas C Tomac, Alan D Agulnick, Norman Haughey, Chen-Fu Chang, Yajun Zhang, Cristina Bäckman, Marisela Morales, Mark P Mattson, Yun Wang, Heiner Westphal, Barry J Hoffe. Effects of cerebral ischemia in mice deficient in Persephin. Proceedings of the National Academy of Sciences of the United States of America. vol 99. issue 14. 2002-08-08. PMID:12093930. |
persephin (pspn), a recently cloned member of the transforming growth factor-beta superfamily (tgf-beta) and glial cell line-derived neurotrophic factor (gdnf) subfamily, is distributed throughout the nervous system at extremely low levels and is thought to function as a survival factor for midbrain dopaminergic and spinal motor neurons in vivo. |
2002-08-08 |
2023-08-12 |
mouse |
| Doreen Siu Yi Leung, Klaus Unsicker, Bernhard Reus. Expression and developmental regulation of gap junction connexins cx26, cx32, cx43 and cx45 in the rat midbrain-floor. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 20. issue 1. 2002-08-07. PMID:12008076. |
we have investigated expression of cx26, cx32, cx43, and cx45 in the midbrain floor, where nigrostriatal dopaminergic neurons originate and differentiate. |
2002-08-07 |
2023-08-12 |
rat |
| Doreen Siu Yi Leung, Klaus Unsicker, Bernhard Reus. Expression and developmental regulation of gap junction connexins cx26, cx32, cx43 and cx45 in the rat midbrain-floor. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 20. issue 1. 2002-08-07. PMID:12008076. |
taken together, our results reveal that expression and ir of cx in the midbrain floor and dopaminergic neurons, respectively, follow cx-type specific patterns that temporally coincide with important steps of midbrain morphogenesis, as e.g. |
2002-08-07 |
2023-08-12 |
rat |
| b' M E G\\xc3\\xb6tz, E Koutsilieri, P Riederer, S Ceccatelli, E Dar\\xc3\\xa. Methylmercury induces neurite degeneration in primary culture of mouse dopaminergic mesencephalic cells. Journal of neural transmission (Vienna, Austria : 1996). vol 109. issue 5-6. 2002-08-06. PMID:12111452.' |
in the present study we have used epifluorescence microscopy and confocal microscopy to investigate the alterations induced by mehg in primary da (dopaminergic) cells isolated from the ventral mesencephalon of cd-1 embryonic mice and cultured for six days in vitro. |
2002-08-06 |
2023-08-12 |
mouse |