| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Elyssa B Margolis, Gregory O Hjelmstad, Antonello Bonci, Howard L Field. Kappa-opioid agonists directly inhibit midbrain dopaminergic neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 31. 2003-12-02. PMID:14602811. |
kappa-opioid agonists directly inhibit midbrain dopaminergic neurons. |
2003-12-02 |
2023-08-12 |
Not clear |
| Haruki Shibata, Hiroshi Katsuki, Mayumi Nishiwaki, Toshiaki Kume, Shuji Kaneko, Akinori Akaik. Lipopolysaccharide-induced dopaminergic cell death in rat midbrain slice cultures: role of inducible nitric oxide synthase and protection by indomethacin. Journal of neurochemistry. vol 86. issue 5. 2003-11-12. PMID:12911628. |
lipopolysaccharide-induced dopaminergic cell death in rat midbrain slice cultures: role of inducible nitric oxide synthase and protection by indomethacin. |
2003-11-12 |
2023-08-12 |
rat |
| Anders Fink-Jensen, Irina Fedorova, Gitta Wörtwein, David P D Woldbye, Thøger Rasmussen, Morgane Thomsen, Tom G Bolwig, Karen M Knitowski, David L McKinzie, Masahisa Yamada, Jürgen Wess, Anthony Basil. Role for M5 muscarinic acetylcholine receptors in cocaine addiction. Journal of neuroscience research. vol 74. issue 1. 2003-11-10. PMID:13130510. |
these m5 receptors modulate the activity of midbrain dopaminergic neurons, which play an important role in mediating reinforcing properties of abused psychostimulants like cocaine. |
2003-11-10 |
2023-08-12 |
mouse |
| Hans Maaswinkel, Lei L. Olfactory input increases visual sensitivity in zebrafish: a possible function for the terminal nerve and dopaminergic interplexiform cells. The Journal of experimental biology. vol 206. issue Pt 13. 2003-11-04. PMID:12771169. |
most of the tn axons terminate in the forebrain and midbrain, but some project via the optic nerve to the neural retina, where they synapse onto dopaminergic interplexiform cells (da-ipcs). |
2003-11-04 |
2023-08-12 |
zebrafish |
| Eliane Comoli, Véronique Coizet, Justin Boyes, J Paul Bolam, Newton S Canteras, Rachel H Quirk, Paul G Overton, Peter Redgrav. A direct projection from superior colliculus to substantia nigra for detecting salient visual events. Nature neuroscience. vol 6. issue 9. 2003-10-28. PMID:12925855. |
midbrain dopaminergic neurons respond to unexpected and biologically salient events, but little is known about the sensory systems underlying this response. |
2003-10-28 |
2023-08-12 |
rat |
| Eliane Comoli, Véronique Coizet, Justin Boyes, J Paul Bolam, Newton S Canteras, Rachel H Quirk, Paul G Overton, Peter Redgrav. A direct projection from superior colliculus to substantia nigra for detecting salient visual events. Nature neuroscience. vol 6. issue 9. 2003-10-28. PMID:12925855. |
here we describe, in the rat, a direct projection from a primary visual structure, the midbrain superior colliculus (sc), to the substantia nigra pars compacta (snc) where direct synaptic contacts are made with both dopaminergic and non-dopaminergic neurons. |
2003-10-28 |
2023-08-12 |
rat |
| Ying Chen, Thomas J W Sharples, Keith G Phillips, Giovanni Benedetti, Lisa M Broad, Ruud Zwart, Emanuele She. The nicotinic alpha 4 beta 2 receptor selective agonist, TC-2559, increases dopamine neuronal activity in the ventral tegmental area of rat midbrain slices. Neuropharmacology. vol 45. issue 3. 2003-09-30. PMID:12871651. |
the ability of alpha4beta2 nicotinic acetylcholine receptors to modulate dopaminergic (da) cell activity in the ventral tegmental area (vta) in rat midbrain slices was assessed using a selective alpha4beta2 receptor agonist, tc-2559 ((e)-n-methyl-4-[3-(5-ethoxypyridin)y1]-3-buten-1-amine). |
2003-09-30 |
2023-08-12 |
human |
| Frédéric Darios, Olga Corti, Christoph B Lücking, Cornelia Hampe, Marie-Paule Muriel, Nacer Abbas, Wen-Jie Gu, Etienne C Hirsch, Thomas Rooney, Merle Ruberg, Alexis Bric. Parkin prevents mitochondrial swelling and cytochrome c release in mitochondria-dependent cell death. Human molecular genetics. vol 12. issue 5. 2003-09-26. PMID:12588799. |
parkin gene mutations have been implicated in autosomal-recessive early-onset parkinsonism and lead to specific degeneration of dopaminergic neurons in midbrain. |
2003-09-26 |
2023-08-12 |
Not clear |
| Keiko Shimizu, Kazuo Matsubara, Ko-ichi Ohtaki, Hiroshi Shion. Paraquat leads to dopaminergic neural vulnerability in organotypic midbrain culture. Neuroscience research. vol 46. issue 4. 2003-09-12. PMID:12871774. |
paraquat leads to dopaminergic neural vulnerability in organotypic midbrain culture. |
2003-09-12 |
2023-08-12 |
rat |
| Cristina Bäckman, Zhi Bing You, Thomas Perlmann, Barry J Hoffe. Elevated locomotor activity without altered striatal dopamine contents in Nurr1 heterozygous mice after acute exposure to methamphetamine. Behavioural brain research. vol 143. issue 1. 2003-09-09. PMID:12842300. |
gene targeting experiments, in which both alleles of the nurr1 gene were deleted, have shown that this molecule plays an essential role in the development of midbrain dopaminergic neurons, as shown by the loss of dopaminergic markers and the neurotransmitter dopamine (da) in the ventral mesencephalon of nurr1 null mutant mice. |
2003-09-09 |
2023-08-12 |
mouse |
| Dong-Youn Hwang, Paul Ardayfio, Un Jung Kang, Elena V Semina, Kwang-Soo Ki. Selective loss of dopaminergic neurons in the substantia nigra of Pitx3-deficient aphakia mice. Brain research. Molecular brain research. vol 114. issue 2. 2003-09-05. PMID:12829322. |
dopaminergic (da) neurons in the ventral midbrain nuclei, substantia nigra pars compacta (snc, a9) and ventral tegmental area (vta, a10), play important roles in the control of movement, emotion, cognition, and reward related behavior. |
2003-09-05 |
2023-08-12 |
mouse |
| Jun Wang, Guiquan Chen, Bai Lu, Chien-ping W. GDNF acutely potentiates Ca2+ channels and excitatory synaptic transmission in midbrain dopaminergic neurons. Neuro-Signals. vol 12. issue 2. 2003-09-04. PMID:12876402. |
gdnf acutely potentiates ca2+ channels and excitatory synaptic transmission in midbrain dopaminergic neurons. |
2003-09-04 |
2023-08-12 |
Not clear |
| Jun Wang, Guiquan Chen, Bai Lu, Chien-ping W. GDNF acutely potentiates Ca2+ channels and excitatory synaptic transmission in midbrain dopaminergic neurons. Neuro-Signals. vol 12. issue 2. 2003-09-04. PMID:12876402. |
glial cell line-derived neurotrophic factor (gdnf) is best known for its long-term survival effect on dopaminergic neurons in the ventral midbrain. |
2003-09-04 |
2023-08-12 |
Not clear |
| Jun Wang, Guiquan Chen, Bai Lu, Chien-ping W. GDNF acutely potentiates Ca2+ channels and excitatory synaptic transmission in midbrain dopaminergic neurons. Neuro-Signals. vol 12. issue 2. 2003-09-04. PMID:12876402. |
these results reveal, for the first time, an acute effect of gdnf on synaptic transmission and its potential mechanisms, and suggest that an important function of gdnf for midbrain dopaminergic neurons is the acute modulation of transmission and ion channels. |
2003-09-04 |
2023-08-12 |
Not clear |
| Hong Gao, Jianjun Wang, Wei Zhang, Yuhui Jiang, Dongbin Niu, Xiaomin Wan. [Recombinant adenovirus carrying glial cell line-derived neurotrophic factor gene protect midbrain dopaminergic neurons in mice]. Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences. vol 35. issue 3. 2003-08-26. PMID:12914240. |
[recombinant adenovirus carrying glial cell line-derived neurotrophic factor gene protect midbrain dopaminergic neurons in mice]. |
2003-08-26 |
2023-08-12 |
mouse |
| Hong Gao, Jianjun Wang, Wei Zhang, Yuhui Jiang, Dongbin Niu, Xiaomin Wan. [Recombinant adenovirus carrying glial cell line-derived neurotrophic factor gene protect midbrain dopaminergic neurons in mice]. Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences. vol 35. issue 3. 2003-08-26. PMID:12914240. |
to observe the protective effects of recombinant adenovirus expressing glial cell line-derived neurotrophic factor (ad-rgdnf) on the midbrain dopaminergic neurons against mptp damage. |
2003-08-26 |
2023-08-12 |
mouse |
| Long Ding, David J Perkel, Michael A Farrie. Presynaptic depression of glutamatergic synaptic transmission by D1-like dopamine receptor activation in the avian basal ganglia. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 14. 2003-08-07. PMID:12853427. |
it also receives dense dopaminergic innervation from the midbrain. |
2003-08-07 |
2023-08-12 |
Not clear |
| Lilla M Farkas, Nicole Dünker, Eleni Roussa, Klaus Unsicker, Kerstin Krieglstei. Transforming growth factor-beta(s) are essential for the development of midbrain dopaminergic neurons in vitro and in vivo. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 12. 2003-08-05. PMID:12832542. |
transforming growth factor-beta(s) are essential for the development of midbrain dopaminergic neurons in vitro and in vivo. |
2003-08-05 |
2023-08-12 |
rat |
| Lilla M Farkas, Nicole Dünker, Eleni Roussa, Klaus Unsicker, Kerstin Krieglstei. Transforming growth factor-beta(s) are essential for the development of midbrain dopaminergic neurons in vitro and in vivo. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 12. 2003-08-05. PMID:12832542. |
development of midbrain dopaminergic neurons is known to depend on inductive signals derived from the ventral midline, including sonic hedgehog (shh) as one of the identified molecules. |
2003-08-05 |
2023-08-12 |
rat |
| Lilla M Farkas, Nicole Dünker, Eleni Roussa, Klaus Unsicker, Kerstin Krieglstei. Transforming growth factor-beta(s) are essential for the development of midbrain dopaminergic neurons in vitro and in vivo. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 12. 2003-08-05. PMID:12832542. |
here we show that in addition to shh, transforming growth factor (tgf)-beta is required for both induction and survival of ventrally located midbrain dopaminergic neurons. |
2003-08-05 |
2023-08-12 |
rat |