| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Olga Corti, Cornelia Hampe, Hana Koutnikova, Frédéric Darios, Sandrine Jacquier, Annick Prigent, Jean-Charles Robinson, Laurent Pradier, Merle Ruberg, Marc Mirande, Etienne Hirsch, Thomas Rooney, Alain Fournier, Alexis Bric. The p38 subunit of the aminoacyl-tRNA synthetase complex is a Parkin substrate: linking protein biosynthesis and neurodegeneration. Human molecular genetics. vol 12. issue 12. 2004-02-06. PMID:12783850. |
analysis of p38 expression in the human adult midbrain revealed strong immunoreactivity in normal dopaminergic neurons and the labeling of lbs in idiopathic pd. |
2004-02-06 |
2023-08-12 |
human |
| Mariette Nordzell, Piia Aarnisalo, Gérard Benoit, Diogo S Castro, Thomas Perlman. Defining an N-terminal activation domain of the orphan nuclear receptor Nurr1. Biochemical and biophysical research communications. vol 313. issue 1. 2004-02-03. PMID:14672718. |
nurr1 is an orphan nuclear receptor essential for the development of midbrain dopaminergic neurons. |
2004-02-03 |
2023-08-12 |
Not clear |
| Barbara K Lipska, Daniel N Lerman, Zin Z Khaing, Daniel R Weinberge. The neonatal ventral hippocampal lesion model of schizophrenia: effects on dopamine and GABA mRNA markers in the rat midbrain. The European journal of neuroscience. vol 18. issue 11. 2004-01-29. PMID:14656305. |
we investigated whether alterations in mrna markers related to the activity of midbrain dopaminergic and gabaergic neurons are associated with this model. |
2004-01-29 |
2023-08-12 |
human |
| Damiana Leo, Eleonora Sorrentino, Floriana Volpicelli, Maria Eyman, Dario Greco, Davide Viggiano, Umberto di Porzio, Carla Perrone-Capan. Altered midbrain dopaminergic neurotransmission during development in an animal model of ADHD. Neuroscience and biobehavioral reviews. vol 27. issue 7. 2004-01-15. PMID:14624810. |
altered midbrain dopaminergic neurotransmission during development in an animal model of adhd. |
2004-01-15 |
2023-08-12 |
rat |
| Gonçalo Castelo-Branco, Joseph Wagner, Francisco J Rodriguez, Julianna Kele, Kyle Sousa, Nina Rawal, Hilda Amalia Pasolli, Elaine Fuchs, Jan Kitajewski, Ernest Arena. Differential regulation of midbrain dopaminergic neuron development by Wnt-1, Wnt-3a, and Wnt-5a. Proceedings of the National Academy of Sciences of the United States of America. vol 100. issue 22. 2004-01-05. PMID:14557550. |
in our study, we examined the contribution of wnts to the development of ventral midbrain (vm) dopaminergic (da) neurons. |
2004-01-05 |
2023-08-12 |
mouse |
| Alexander Storch, Henry A Lester, Bernhard O Boehm, Johannes Schwar. Functional characterization of dopaminergic neurons derived from rodent mesencephalic progenitor cells. Journal of chemical neuroanatomy. vol 26. issue 2. 2004-01-05. PMID:14599663. |
furthermore, we detect a slowly activating hyperpolarization-activated inward cation current (i(h)), which is specific for dopaminergic neurons among present midbrain neurons. |
2004-01-05 |
2023-08-12 |
human |
| Simone M Smits, Tiia Ponnio, Orla M Conneely, J Peter H Burbach, Marten P Smid. Involvement of Nurr1 in specifying the neurotransmitter identity of ventral midbrain dopaminergic neurons. The European journal of neuroscience. vol 18. issue 7. 2003-12-19. PMID:14622207. |
involvement of nurr1 in specifying the neurotransmitter identity of ventral midbrain dopaminergic neurons. |
2003-12-19 |
2023-08-12 |
mouse |
| Todd B Sherer, Ranjita Betarbet, Claudia M Testa, Byoung Boo Seo, Jason R Richardson, Jin Ho Kim, Gary W Miller, Takao Yagi, Akemi Matsuno-Yagi, J Timothy Greenamyr. Mechanism of toxicity in rotenone models of Parkinson's disease. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 34. 2003-12-16. PMID:14645467. |
to determine the relevance of rotenone-induced oxidative damage to dopaminergic neuronal death, we used a chronic midbrain slice culture model. |
2003-12-16 |
2023-08-12 |
human |
| Todd B Sherer, Ranjita Betarbet, Claudia M Testa, Byoung Boo Seo, Jason R Richardson, Jin Ho Kim, Gary W Miller, Takao Yagi, Akemi Matsuno-Yagi, J Timothy Greenamyr. Mechanism of toxicity in rotenone models of Parkinson's disease. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 34. 2003-12-16. PMID:14645467. |
finally, brains from rotenone-treated animals demonstrated oxidative damage, most notably in midbrain and olfactory bulb, dopaminergic regions affected by parkinson's disease. |
2003-12-16 |
2023-08-12 |
human |
| R Eilam, Y Peter, Y Groner, M Sega. Late degeneration of nigro-striatal neurons in ATM-/- mice. Neuroscience. vol 121. issue 1. 2003-12-05. PMID:12946702. |
these findings indicate that midbrain dopaminergic neurons in atm-/- mice initially send normal axons to the striatum, only to degenerate later in life. |
2003-12-05 |
2023-08-12 |
mouse |
| Amelia Sánchez-Capelo, Philippe Colin, Bernard Guibert, Nicole Faucon Biguet, Jacques Malle. Transforming growth factor beta1 overexpression in the nigrostriatal system increases the dopaminergic deficit of MPTP mice. Molecular and cellular neurosciences. vol 23. issue 4. 2003-12-04. PMID:12932441. |
in the absence of mptp, tgfbeta1 greatly decreased the number of dopaminergic neurons in the ventral mesencephalon of fully mature mice. |
2003-12-04 |
2023-08-12 |
mouse |
| Guillaume Hébert, Josette Arsaut, Robert Dantzer, Jacques Demotes-Mainar. Time-course of the expression of inflammatory cytokines and matrix metalloproteinases in the striatum and mesencephalon of mice injected with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, a dopaminergic neurotoxin. Neuroscience letters. vol 349. issue 3. 2003-12-04. PMID:12951201. |
time-course of the expression of inflammatory cytokines and matrix metalloproteinases in the striatum and mesencephalon of mice injected with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, a dopaminergic neurotoxin. |
2003-12-04 |
2023-08-12 |
mouse |
| Elyssa B Margolis, Gregory O Hjelmstad, Antonello Bonci, Howard L Field. Kappa-opioid agonists directly inhibit midbrain dopaminergic neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 31. 2003-12-02. PMID:14602811. |
kappa-opioid agonists directly inhibit midbrain dopaminergic neurons. |
2003-12-02 |
2023-08-12 |
Not clear |
| Haruki Shibata, Hiroshi Katsuki, Mayumi Nishiwaki, Toshiaki Kume, Shuji Kaneko, Akinori Akaik. Lipopolysaccharide-induced dopaminergic cell death in rat midbrain slice cultures: role of inducible nitric oxide synthase and protection by indomethacin. Journal of neurochemistry. vol 86. issue 5. 2003-11-12. PMID:12911628. |
lipopolysaccharide-induced dopaminergic cell death in rat midbrain slice cultures: role of inducible nitric oxide synthase and protection by indomethacin. |
2003-11-12 |
2023-08-12 |
rat |
| Anders Fink-Jensen, Irina Fedorova, Gitta Wörtwein, David P D Woldbye, Thøger Rasmussen, Morgane Thomsen, Tom G Bolwig, Karen M Knitowski, David L McKinzie, Masahisa Yamada, Jürgen Wess, Anthony Basil. Role for M5 muscarinic acetylcholine receptors in cocaine addiction. Journal of neuroscience research. vol 74. issue 1. 2003-11-10. PMID:13130510. |
these m5 receptors modulate the activity of midbrain dopaminergic neurons, which play an important role in mediating reinforcing properties of abused psychostimulants like cocaine. |
2003-11-10 |
2023-08-12 |
mouse |
| Hans Maaswinkel, Lei L. Olfactory input increases visual sensitivity in zebrafish: a possible function for the terminal nerve and dopaminergic interplexiform cells. The Journal of experimental biology. vol 206. issue Pt 13. 2003-11-04. PMID:12771169. |
most of the tn axons terminate in the forebrain and midbrain, but some project via the optic nerve to the neural retina, where they synapse onto dopaminergic interplexiform cells (da-ipcs). |
2003-11-04 |
2023-08-12 |
zebrafish |
| Eliane Comoli, Véronique Coizet, Justin Boyes, J Paul Bolam, Newton S Canteras, Rachel H Quirk, Paul G Overton, Peter Redgrav. A direct projection from superior colliculus to substantia nigra for detecting salient visual events. Nature neuroscience. vol 6. issue 9. 2003-10-28. PMID:12925855. |
midbrain dopaminergic neurons respond to unexpected and biologically salient events, but little is known about the sensory systems underlying this response. |
2003-10-28 |
2023-08-12 |
rat |
| Eliane Comoli, Véronique Coizet, Justin Boyes, J Paul Bolam, Newton S Canteras, Rachel H Quirk, Paul G Overton, Peter Redgrav. A direct projection from superior colliculus to substantia nigra for detecting salient visual events. Nature neuroscience. vol 6. issue 9. 2003-10-28. PMID:12925855. |
here we describe, in the rat, a direct projection from a primary visual structure, the midbrain superior colliculus (sc), to the substantia nigra pars compacta (snc) where direct synaptic contacts are made with both dopaminergic and non-dopaminergic neurons. |
2003-10-28 |
2023-08-12 |
rat |
| Ying Chen, Thomas J W Sharples, Keith G Phillips, Giovanni Benedetti, Lisa M Broad, Ruud Zwart, Emanuele She. The nicotinic alpha 4 beta 2 receptor selective agonist, TC-2559, increases dopamine neuronal activity in the ventral tegmental area of rat midbrain slices. Neuropharmacology. vol 45. issue 3. 2003-09-30. PMID:12871651. |
the ability of alpha4beta2 nicotinic acetylcholine receptors to modulate dopaminergic (da) cell activity in the ventral tegmental area (vta) in rat midbrain slices was assessed using a selective alpha4beta2 receptor agonist, tc-2559 ((e)-n-methyl-4-[3-(5-ethoxypyridin)y1]-3-buten-1-amine). |
2003-09-30 |
2023-08-12 |
human |
| Frédéric Darios, Olga Corti, Christoph B Lücking, Cornelia Hampe, Marie-Paule Muriel, Nacer Abbas, Wen-Jie Gu, Etienne C Hirsch, Thomas Rooney, Merle Ruberg, Alexis Bric. Parkin prevents mitochondrial swelling and cytochrome c release in mitochondria-dependent cell death. Human molecular genetics. vol 12. issue 5. 2003-09-26. PMID:12588799. |
parkin gene mutations have been implicated in autosomal-recessive early-onset parkinsonism and lead to specific degeneration of dopaminergic neurons in midbrain. |
2003-09-26 |
2023-08-12 |
Not clear |