Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Doug W Smith, Theodore Friedman. Discrepant effects of culture conditions on survival and function of dopaminergic neurons. Neuroreport. vol 15. issue 6. 2004-06-29. PMID:15076727. |
primary midbrain cultures are valuable for probing the function of dopaminergic neurons and for elucidating the factors that cause their dysfunction and degeneration. |
2004-06-29 |
2023-08-12 |
Not clear |
Fumie Yasumoto, Takayuki Negishi, Yoshiyuki Ishii, Shigeru Kyuwa, Yoichiro Kuroda, Yasuhiro Yoshikaw. Endogenous dopamine maintains synchronous oscillation of intracellular calcium in primary cultured-mouse midbrain neurons. Cellular and molecular neurobiology. vol 24. issue 1. 2004-06-28. PMID:15049510. |
synchronous oscillation of midbrain neurons would be a useful tool for in vitro researches into various neural disorders directly or indirectly caused by dopaminergic neurons. |
2004-06-28 |
2023-08-12 |
Not clear |
Hannu Sariola, Mart Saarm. Novel functions and signalling pathways for GDNF. Journal of cell science. vol 116. issue Pt 19. 2004-06-24. PMID:12953054. |
glial-cell-line-derived neurotrophic factor (gdnf) was originally identified as a survival factor for midbrain dopaminergic neurons. |
2004-06-24 |
2023-08-12 |
Not clear |
Maria G Macedo, Burcu Anar, Iraad F Bronner, Milena Cannella, Ferdinando Squitieri, Vincenzo Bonifati, André Hoogeveen, Peter Heutink, Patrizia Rizz. The DJ-1L166P mutant protein associated with early onset Parkinson's disease is unstable and forms higher-order protein complexes. Human molecular genetics. vol 12. issue 21. 2004-06-22. PMID:12952867. |
parkinson's disease (pd) is a common neurodegenerative disorder that involves the selective degeneration of midbrain dopaminergic neurons. |
2004-06-22 |
2023-08-12 |
Not clear |
Raffaella Geracitano, Mauro Federici, Simonetta Prisco, Giorgio Bernardi, Nicola B Mercur. Inhibitory effects of trace amines on rat midbrain dopaminergic neurons. Neuropharmacology. vol 46. issue 6. 2004-06-21. PMID:15033340. |
inhibitory effects of trace amines on rat midbrain dopaminergic neurons. |
2004-06-21 |
2023-08-12 |
rat |
Anton Reiner, David J Perkel, Laura L Bruce, Ann B Butler, András Csillag, Wayne Kuenzel, Loreta Medina, George Paxinos, Toru Shimizu, Georg Striedter, Martin Wild, Gregory F Ball, Sarah Durand, Onur Güntürkün, Diane W Lee, Claudio V Mello, Alice Powers, Stephanie A White, Gerald Hough, Lubica Kubikova, Tom V Smulders, Kazuhiro Wada, Jennifer Dugas-Ford, Scott Husband, Keiko Yamamoto, Jing Yu, Connie Siang, Erich D Jarvis, Onur Gütürkü. Revised nomenclature for avian telencephalon and some related brainstem nuclei. The Journal of comparative neurology. vol 473. issue 3. 2004-06-21. PMID:15116397. |
the midbrain dopaminergic cell group in birds known as the nucleus tegmenti pedunculopontinus pars compacta was recognized as homologous to the mammalian substantia nigra pars compacta and was renamed accordingly; a group of gamma-aminobutyric acid (gaba)ergic neurons at the lateral edge of this region was identified as homologous to the mammalian substantia nigra pars reticulata and was also renamed accordingly. |
2004-06-21 |
2023-08-12 |
pigeon |
Darren C Robertson, Oliver Schmidt, Natalia Ninkina, Paul A Jones, John Sharkey, Vladimir L Buchma. Developmental loss and resistance to MPTP toxicity of dopaminergic neurones in substantia nigra pars compacta of gamma-synuclein, alpha-synuclein and double alpha/gamma-synuclein null mutant mice. Journal of neurochemistry. vol 89. issue 5. 2004-06-18. PMID:15147505. |
we studied the effect of inactivation of gamma-synuclein gene on mouse midbrain dopaminergic neurones. |
2004-06-18 |
2023-08-12 |
mouse |
Kazuya Saitoh, Tadashi Isa, Kaoru Takakusak. Nigral GABAergic inhibition upon mesencephalic dopaminergic cell groups in rats. The European journal of neuroscience. vol 19. issue 9. 2004-06-14. PMID:15128394. |
synaptic inhibition from the substantia nigra pars reticulata (snr) to the mesencephalic dopaminergic neurons, which was mediated by gamma (gamma)-amino-butyric acid (gaba), was investigated in a midbrain slice preparation of wistar rats. |
2004-06-14 |
2023-08-12 |
rat |
Chang-Lin Liang, Omar Nelson, Umar Yazdani, Parichehr Pasbakhsh, Dwight C Germa. Inverse relationship between the contents of neuromelanin pigment and the vesicular monoamine transporter-2: human midbrain dopamine neurons. The Journal of comparative neurology. vol 473. issue 1. 2004-05-24. PMID:15067721. |
these data support the hypothesis that midbrain dopaminergic neurons that synthesize greater amounts of dopamine have more vesicular storage capacity for action potential-induced release of transmitter and that the ventral sn neurons accumulate the most neuromelanin pigment, in part because they have the least vmat2 protein. |
2004-05-24 |
2023-08-12 |
human |
D Shohamy, C E Myers, S Grossman, J Sage, M A Gluck, R A Poldrac. Cortico-striatal contributions to feedback-based learning: converging data from neuroimaging and neuropsychology. Brain : a journal of neurology. vol 127. issue Pt 4. 2004-05-20. PMID:15013954. |
these findings also link between learning impairments in parkinson's disease and the physiological and computational evidence for the role of midbrain dopaminergic systems in feedback processing. |
2004-05-20 |
2023-08-12 |
Not clear |
Suling Zhao, Sarah Maxwell, Antonio Jimenez-Beristain, Joaquim Vives, Eva Kuehner, Jiexin Zhao, Carmel O'Brien, Carmen de Felipe, Elena Semina, Meng L. Generation of embryonic stem cells and transgenic mice expressing green fluorescence protein in midbrain dopaminergic neurons. The European journal of neuroscience. vol 19. issue 5. 2004-05-05. PMID:15016072. |
generation of embryonic stem cells and transgenic mice expressing green fluorescence protein in midbrain dopaminergic neurons. |
2004-05-05 |
2023-08-12 |
mouse |
Kai-Christian Sonntag, Rabi Simantov, Kwang-Soo Kim, Ole Isacso. Temporally induced Nurr1 can induce a non-neuronal dopaminergic cell type in embryonic stem cell differentiation. The European journal of neuroscience. vol 19. issue 5. 2004-05-05. PMID:15016073. |
the nuclear transcription factor nurr1 is involved in the development and maintenance of the midbrain dopaminergic (da) neuronal phenotype. |
2004-05-05 |
2023-08-12 |
Not clear |
Satoshi Horiguchi, Jun Takahashi, Yo Kishi, Asuka Morizane, Yo Okamoto, Masaomi Koyanagi, Masayuki Tsuji, Kei Tashiro, Tasuku Honjo, Shingo Fujii, Nobuo Hashimot. Neural precursor cells derived from human embryonic brain retain regional specificity. Journal of neuroscience research. vol 75. issue 6. 2004-05-03. PMID:14994342. |
furthermore, the th-positive cells from diencephalic and mesencephalic precursors were large, multipolar, and gamma-aminobutyric acid (gaba)-negative, which suggested that these cells were midbrain dopaminergic neurons. |
2004-05-03 |
2023-08-12 |
human |
R G Wiley, M B Harrison, A I Levey, D A Lapp. Destruction of midbrain dopaminergic neurons by using immunotoxin to dopamine transporter. Cellular and molecular neurobiology. vol 23. issue 4-5. 2004-04-30. PMID:14514035. |
destruction of midbrain dopaminergic neurons by using immunotoxin to dopamine transporter. |
2004-04-30 |
2023-08-12 |
rat |
R G Wiley, M B Harrison, A I Levey, D A Lapp. Destruction of midbrain dopaminergic neurons by using immunotoxin to dopamine transporter. Cellular and molecular neurobiology. vol 23. issue 4-5. 2004-04-30. PMID:14514035. |
in the present study, we sought to determine if a monoclonal antibody to the dopamine transporter (anti-dat) could be used to target midbrain dopaminergic neurons. |
2004-04-30 |
2023-08-12 |
rat |
R G Wiley, M B Harrison, A I Levey, D A Lapp. Destruction of midbrain dopaminergic neurons by using immunotoxin to dopamine transporter. Cellular and molecular neurobiology. vol 23. issue 4-5. 2004-04-30. PMID:14514035. |
these results show that anti-dat can be used to target midbrain dopaminergic neurons and that anti-dat-saporin may be useful for producing a lesion very similar to the naturally occurring neural degeneration seen in parkinson's disease. |
2004-04-30 |
2023-08-12 |
rat |
K Radad, G Gille, R Moldzio, H Saito, K Ishige, W-D Rausc. Ginsenosides Rb1 and Rg1 effects on survival and neurite growth of MPP+-affected mesencephalic dopaminergic cells. Journal of neural transmission (Vienna, Austria : 1996). vol 111. issue 1. 2004-04-30. PMID:14714214. |
in our study, primary cultures from embryonic mouse mesencephalon are applied to examine the effects of these two ginsenosides on neuritic growth of dopaminergic cells and their survival affected by 1-methyl-4-phenylpyridinium-iodide (mpp(+)). |
2004-04-30 |
2023-08-12 |
mouse |
Hideki Okada, Natsuki Matsushita, Kenta Kobayashi, Kazuto Kobayash. Identification of GABAA receptor subunit variants in midbrain dopaminergic neurons. Journal of neurochemistry. vol 89. issue 1. 2004-04-26. PMID:15030384. |
identification of gabaa receptor subunit variants in midbrain dopaminergic neurons. |
2004-04-26 |
2023-08-12 |
mouse |
Diego M Gelman, Daniela Noaín, M Elena Avale, Verónica Otero, Malcolm J Low, Marcelo Rubinstei. Transgenic mice engineered to target Cre/loxP-mediated DNA recombination into catecholaminergic neurons. Genesis (New York, N.Y. : 2000). vol 36. issue 4. 2004-04-23. PMID:12929090. |
immunohistochemistry performed on transgenic mouse brain sections revealed a high number of cells expressing cre in areas where th is normally expressed, including the olfactory bulb, hypothalamic and midbrain dopaminergic neurons, and the locus coeruleus. |
2004-04-23 |
2023-08-12 |
mouse |
Jae-Won Shim, Hyun-Chul Koh, Mi-Yoon Chang, Eun Roh, Cha-Yong Choi, Young J Oh, Hyeon Son, Yong-Sung Lee, Lorenz Studer, Sang-Hun Le. Enhanced in vitro midbrain dopamine neuron differentiation, dopaminergic function, neurite outgrowth, and 1-methyl-4-phenylpyridium resistance in mouse embryonic stem cells overexpressing Bcl-XL. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 4. 2004-04-12. PMID:14749429. |
enhanced in vitro midbrain dopamine neuron differentiation, dopaminergic function, neurite outgrowth, and 1-methyl-4-phenylpyridium resistance in mouse embryonic stem cells overexpressing bcl-xl. |
2004-04-12 |
2023-08-12 |
mouse |