| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Daniela Rossi, Liliana Brambilla, Chiara F Valori, Andrea Crugnola, Giorgio Giaccone, Raffaella Capobianco, Michela Mangieri, Ann E Kingston, Alain Bloc, Paola Bezzi, Andrea Volterr. Defective tumor necrosis factor-alpha-dependent control of astrocyte glutamate release in a transgenic mouse model of Alzheimer disease. The Journal of biological chemistry. vol 280. issue 51. 2006-04-04. PMID:16253995. |
defective tumor necrosis factor-alpha-dependent control of astrocyte glutamate release in a transgenic mouse model of alzheimer disease. |
2006-04-04 |
2023-08-12 |
mouse |
| Daniela Rossi, Liliana Brambilla, Chiara F Valori, Andrea Crugnola, Giorgio Giaccone, Raffaella Capobianco, Michela Mangieri, Ann E Kingston, Alain Bloc, Paola Bezzi, Andrea Volterr. Defective tumor necrosis factor-alpha-dependent control of astrocyte glutamate release in a transgenic mouse model of Alzheimer disease. The Journal of biological chemistry. vol 280. issue 51. 2006-04-04. PMID:16253995. |
acute inflammation in vitro, induced by adding reactive microglia to astrocyte cultures, enhances tnfalpha production and amplifies glutamate release, switching the pathway into a neurodamaging cascade (bezzi, p., domercq, m., brambilla, l., galli, r., schols, d., de clercq, e., vescovi, a., bagetta, g., kollias, g., meldolesi, j., and volterra, a. |
2006-04-04 |
2023-08-12 |
mouse |
| Nader Binesh, Amir Huda, M Albert Thomas, Nathaniel Wyckoff, Mary Bugbee, Steven Han, Natalie Rasgon, Pablo Davanzo, James Sayre, Barry Guze, Paul Martin, Fawzy Fawz. Hepatic encephalopathy: a neurochemical, neuroanatomical, and neuropsychological study. Journal of applied clinical medical physics. vol 7. issue 1. 2006-04-03. PMID:16518320. |
in summary, this study partially confirms a hypothesized mechanism of he pathogenesis, an increased synthesis of glutamine by brain glutamate in astrocytes due to excessive blood ammonia, followed by a compensatory loss of myo-inositol to maintain astrocyte volume homeostasis. |
2006-04-03 |
2023-08-12 |
Not clear |
| Andrew Charle. Reaching out beyond the synapse: glial intercellular waves coordinate metabolism. Science's STKE : signal transduction knowledge environment. vol 2005. issue 270. 2006-03-31. PMID:15701894. |
neuronal activity can stimulate an increase in astrocyte intracellular calcium concentration, which is propagated through neighboring astrocytes as a "calcium wave"; these calcium waves are accompanied by the release of glutamate. |
2006-03-31 |
2023-08-12 |
Not clear |
| Daniela Caccamo, Agata Campisi, Monica Currò, Mohammed Aguennouz, Giovanni Li Volti, Roberto Avola, Riccardo Ientil. Nuclear factor-kappab activation is associated with glutamate-evoked tissue transglutaminase up-regulation in primary astrocyte cultures. Journal of neuroscience research. vol 82. issue 6. 2006-03-14. PMID:16273541. |
we have previously demonstrated that alterations of cell redox state, evoked by glutamate, are associated with tissue transglutaminase increases in primary astrocyte cultures. |
2006-03-14 |
2023-08-12 |
Not clear |
| Daniela Caccamo, Agata Campisi, Monica Currò, Mohammed Aguennouz, Giovanni Li Volti, Roberto Avola, Riccardo Ientil. Nuclear factor-kappab activation is associated with glutamate-evoked tissue transglutaminase up-regulation in primary astrocyte cultures. Journal of neuroscience research. vol 82. issue 6. 2006-03-14. PMID:16273541. |
these preliminary data suggest that nf-kappab activation, which has been demonstrated to be involved in astrocyte response to glutamate, could also be associated with the molecular pathway leading to glutamate-evoked tissue transglutaminase up-regulation. |
2006-03-14 |
2023-08-12 |
Not clear |
| Raima Larter, Melissa Glendening Crai. Glutamate-induced glutamate release: a proposed mechanism for calcium bursting in astrocytes. Chaos (Woodbury, N.Y.). vol 15. issue 4. 2006-03-14. PMID:16396604. |
the glutamate feedback process considered here is shown to be critical for the generation of complex bursting oscillations in the astrocytes and to, perhaps, code for information which may be passed from neuron to neuron via the astrocyte. |
2006-03-14 |
2023-08-12 |
Not clear |
| Didier De Saint Jan, Gary L Westbroo. Detecting activity in olfactory bulb glomeruli with astrocyte recording. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 11. 2006-03-13. PMID:15772351. |
the astrocyte k+ current was dependent on ampa and nmda receptors in mitral/tufted cells as well as on a previously undescribed metabotropic glutamate receptor 1 component. |
2006-03-13 |
2023-08-12 |
Not clear |
| Raymond C Koehler, Debebe Gebremedhin, David R Harde. Role of astrocytes in cerebrovascular regulation. Journal of applied physiology (Bethesda, Md. : 1985). vol 100. issue 1. 2006-02-01. PMID:16357084. |
the increase in astrocyte calcium after neuronal activation is mediated, in part, by activation of metabotropic glutamate receptors. |
2006-02-01 |
2023-08-12 |
Not clear |
| Ning Kang, Jun Xu, Qiwu Xu, Maiken Nedergaard, Jian Kan. Astrocytic glutamate release-induced transient depolarization and epileptiform discharges in hippocampal CA1 pyramidal neurons. Journal of neurophysiology. vol 94. issue 6. 2006-01-25. PMID:16162834. |
the neuronal stc is mediated by ionotropic glutamate receptors leading to the td and epileptiform discharges; while the astrocytic tc is a glutamate reuptake current resulting from transporting released glutamate into the patched astrocyte. |
2006-01-25 |
2023-08-12 |
Not clear |
| Daniela Caccamo, Agata Campisi, Monica Currò, Vincenzo Bramanti, Michelangelo Tringali, Giovanni Li Volti, Angelo Vanella, Riccardo Ientil. Antioxidant treatment inhibited glutamate-evoked NF-kappaB activation in primary astroglial cell cultures. Neurotoxicology. vol 26. issue 5. 2005-12-22. PMID:15894376. |
altogether, these data confirm that the nf-kappab pathway is involved in cell response to oxidative stress induced by glutamate injury in primary astrocyte cultures, and suggest that the use of antioxidants, such as irfi 016, may be a helpful pharmacological strategy for neuroprotection. |
2005-12-22 |
2023-08-12 |
Not clear |
| Yun Zhang, Gang H. [Iptakalim enhances astrocytic glutamate uptake activity]. Yao xue xue bao = Acta pharmaceutica Sinica. vol 39. issue 12. 2005-12-14. PMID:15813025. |
to investigate the effect of iptakalim (ipt), a novel atp-sensitive potassium channel opener (katpco), on astrocyte glutamate uptake activity. |
2005-12-14 |
2023-08-12 |
Not clear |
| Dieter Häussinger, Freimut Schlies. Astrocyte swelling and protein tyrosine nitration in hepatic encephalopathy. Neurochemistry international. vol 47. issue 1-2. 2005-09-01. PMID:15908046. |
recent findings suggest a close interrelation between astrocyte swelling, nmda receptor signaling, glutamate, oxidative stress and nitric oxide, which may result in mutual amplification of swelling and oxidative stress. |
2005-09-01 |
2023-08-12 |
Not clear |
| Jaekwang Lee, M Tommerdahl, O V Favorov, B L Whitse. Optically recorded response of the superficial dorsal horn: dissociation from neuronal activity, sensitivity to formalin-evoked skin nociceptor activation. Journal of neurophysiology. vol 94. issue 1. 2005-08-16. PMID:15744009. |
these observations from slices from normal subjects are interpreted to indicate that the ois(dr) mainly reflects cell volume and light scattering changes associated with dh(s) astrocyte uptake of k+ and glutamate (glu). |
2005-08-16 |
2023-08-12 |
human |
| Daniela Caccamo, Agata Campisi, Herbert Marini, Elena B Adamo, Giovanni Li Volti, Francesco Squadrito, Riccardo Ientil. Glutamate promotes NF-kappaB pathway in primary astrocytes: protective effects of IRFI 016, a synthetic vitamin E analogue. Experimental neurology. vol 193. issue 2. 2005-07-15. PMID:15869940. |
a prolonged exposure to glutamate (24 h) caused a depletion of intracellular glutathione that, in astroglial cells, has been considered a biochemical change typical of early astrocyte dysfunction, leading to cell alterations occurring in the gliosis. |
2005-07-15 |
2023-08-12 |
Not clear |
| Daniela Caccamo, Agata Campisi, Herbert Marini, Elena B Adamo, Giovanni Li Volti, Francesco Squadrito, Riccardo Ientil. Glutamate promotes NF-kappaB pathway in primary astrocytes: protective effects of IRFI 016, a synthetic vitamin E analogue. Experimental neurology. vol 193. issue 2. 2005-07-15. PMID:15869940. |
altogether, these data confirm that gsh content plays a pivotal role to determine oxidative response to glutamate injury in primary astrocyte cultures and that nf-kappab pathway is involved in this response. |
2005-07-15 |
2023-08-12 |
Not clear |
| Ainara Vallejo-Illarramendi, Mónica Torres-Ramos, Marcello Melone, Fiorenzo Conti, Carlos Matut. Clozapine reduces GLT-1 expression and glutamate uptake in astrocyte cultures. Glia. vol 50. issue 3. 2005-06-30. PMID:15739191. |
clozapine reduces glt-1 expression and glutamate uptake in astrocyte cultures. |
2005-06-30 |
2023-08-12 |
Not clear |
| Ainara Vallejo-Illarramendi, Mónica Torres-Ramos, Marcello Melone, Fiorenzo Conti, Carlos Matut. Clozapine reduces GLT-1 expression and glutamate uptake in astrocyte cultures. Glia. vol 50. issue 3. 2005-06-30. PMID:15739191. |
to test the hypothesis that clozapine-induced reduction of glutamate transporter-1 (glt-1) expression is mediated by astrocytes, we studied the effects of clozapine on glu transporters and glu uptake in primary astrocyte cultures of the cerebral cortex. |
2005-06-30 |
2023-08-12 |
Not clear |
| Hai Chen, Dandan Su. The role of Na-K-Cl co-transporter in cerebral ischemia. Neurological research. vol 27. issue 3. 2005-06-13. PMID:15845211. |
our recent studies suggest that nkcc1 activation leads to high [k(+)](o(-)) induced astrocyte swelling and glutamate release, as well as neuronal na(+) , and cl(-) influx during acute excitotoxicity. |
2005-06-13 |
2023-08-12 |
Not clear |
| Chunlong Zhong, Xueren Zhao, Jayaprakash Sarva, Alan Kozikowski, Joseph H Neale, Bruce G Lyet. NAAG peptidase inhibitor reduces acute neuronal degeneration and astrocyte damage following lateral fluid percussion TBI in rats. Journal of neurotrauma. vol 22. issue 2. 2005-05-03. PMID:15716632. |
we conclude that the naag peptidase inhibitor zj-43 is a potential novel strategy to reduce both neuronal and astrocyte damage associated with the glutamate excitotoxicity after tbi. |
2005-05-03 |
2023-08-12 |
rat |