| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Hachimi-Idrissi, A Van Hemelrijck, A Michotte, I Smolders, S Sarre, G Ebinger, L Huyghens, Y Michott. Postischemic mild hypothermia reduces neurotransmitter release and astroglial cell proliferation during reperfusion after asphyxial cardiac arrest in rats. Brain research. vol 1019. issue 1-2. 2004-11-04. PMID:15306256. |
the present study investigated whether postischemic mild hypothermia attenuates the ischemia-induced striatal glutamate (glu) and dopamine (da) release, as well as astroglial cell proliferation in the brain. |
2004-11-04 |
2023-08-12 |
rat |
| E Pretorius, J Mar. Direct and indirect effects of corticosteroids on astrocyte function. Reviews in the neurosciences. vol 15. issue 3. 2004-10-08. PMID:15357142. |
we discuss the direct effects that corticosteroids have on astrocyte physiology and functioning; these include inhibited glucose transport, decreased glycogen synthesis and decreased glutamate uptake. |
2004-10-08 |
2023-08-12 |
Not clear |
| Diogo Losch de Oliveira, Joel Felipe Horn, Juliana Moura Rodrigues, Marcos E S Frizzo, Emílio Moriguchi, Diogo Onofre Souza, Susana Wofchu. Quinolinic acid promotes seizures and decreases glutamate uptake in young rats: reversal by orally administered guanosine. Brain research. vol 1018. issue 1. 2004-10-06. PMID:15262204. |
guanosine systemically administered prevents quinolinic acid-induced seizures in adult mice and increases basal glutamate uptake by cortical astrocyte culture and slices from young rats. |
2004-10-06 |
2023-08-12 |
mouse |
| D Ramonet, M J Rodríguez, K Fredriksson, F Bernal, N Mah. In vivo neuroprotective adaptation of the glutamate/glutamine cycle to neuronal death. Hippocampus. vol 14. issue 5. 2004-10-04. PMID:15301436. |
astrocyte uptake and recycling of synaptic glutamate as glutamine is a major metabolic pathway dependent on energy metabolism, which inter-relationships are not fully understood and remain controversial. |
2004-10-04 |
2023-08-12 |
Not clear |
| Yanhua H Huang, Dwight E Bergle. Glutamate transporters bring competition to the synapse. Current opinion in neurobiology. vol 14. issue 3. 2004-09-28. PMID:15194115. |
astrocytes express the highest density of gluts and dominate clearance away from these receptors; synapses that are not associated with astrocyte processes experience greater mglur activation and can be exposed to glutamate released at adjacent synapses. |
2004-09-28 |
2023-08-12 |
Not clear |
| Nagatoki Kinoshita, Kazushi Kimura, Naoya Matsumoto, Masahiko Watanabe, Masahiro Fukaya, Chizuka Id. Mammalian septin Sept2 modulates the activity of GLAST, a glutamate transporter in astrocytes. Genes to cells : devoted to molecular & cellular mechanisms. vol 9. issue 1. 2004-09-24. PMID:14723703. |
the present study revealed that sept2 co-localizes with the astrocyte glutamate transporter glast in the bergmann glial processes facing axons and synapses. |
2004-09-24 |
2023-08-12 |
Not clear |
| Scott Wilke, Robert Thomas, Natalie Allcock, Robert Fer. Mechanism of acute ischemic injury of oligodendroglia in early myelinating white matter: the importance of astrocyte injury and glutamate release. Journal of neuropathology and experimental neurology. vol 63. issue 8. 2004-09-14. PMID:15330341. |
mechanism of acute ischemic injury of oligodendroglia in early myelinating white matter: the importance of astrocyte injury and glutamate release. |
2004-09-14 |
2023-08-12 |
rat |
| Ethan G Hughes, Jamie L Maguire, Melanie T McMinn, Rachael E Scholz, Margaret L Sutherlan. Loss of glial fibrillary acidic protein results in decreased glutamate transport and inhibition of PKA-induced EAAT2 cell surface trafficking. Brain research. Molecular brain research. vol 124. issue 2. 2004-08-26. PMID:15135219. |
analysis of primary cortical astrocyte cultures prepared from gfap null and wild type mice demonstrated that loss of gfap results in an inability to traffic the glial glutamate transporter, eaat2, to the surface of the cell following protein kinase a (pka) stimulation by dibutyryl camp. |
2004-08-26 |
2023-08-12 |
mouse |
| Yanhua H Huang, Saurabh R Sinha, Kohichi Tanaka, Jeffrey D Rothstein, Dwight E Bergle. Astrocyte glutamate transporters regulate metabotropic glutamate receptor-mediated excitation of hippocampal interneurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 19. 2004-08-13. PMID:15140926. |
astrocyte glutamate transporters regulate metabotropic glutamate receptor-mediated excitation of hippocampal interneurons. |
2004-08-13 |
2023-08-12 |
mouse |
| Richard Piet, Dominique A Poulain, Stéphane H R Olie. Contribution of astrocytes to synaptic transmission in the rat supraoptic nucleus. Neurochemistry international. vol 45. issue 2-3. 2004-07-26. PMID:15145540. |
the use of pharmacological inhibitors of glutamate transporters on this model, in which a physiological change in the astrocyte environment occurs, has brought new insights on the contribution of astrocytes to both excitatory and inhibitory neurotransmissions. |
2004-07-26 |
2023-08-12 |
rat |
| Linda Bambrick, Tibor Kristian, Gary Fisku. Astrocyte mitochondrial mechanisms of ischemic brain injury and neuroprotection. Neurochemical research. vol 29. issue 3. 2004-06-29. PMID:15038607. |
ischemic alterations to astrocyte energy metabolism and the uptake and metabolism of the excitatory amino acid transmitter glutamate may be particularly important. |
2004-06-29 |
2023-08-12 |
Not clear |
| Marcos Emílio dos Santos Frizzo, Leonara Patrícia Dall'Onder, Karina Borges Dalcin, Diogo Onofre Souz. Riluzole enhances glutamate uptake in rat astrocyte cultures. Cellular and molecular neurobiology. vol 24. issue 1. 2004-06-28. PMID:15049516. |
riluzole enhances glutamate uptake in rat astrocyte cultures. |
2004-06-28 |
2023-08-12 |
rat |
| Marcos Emílio dos Santos Frizzo, Leonara Patrícia Dall'Onder, Karina Borges Dalcin, Diogo Onofre Souz. Riluzole enhances glutamate uptake in rat astrocyte cultures. Cellular and molecular neurobiology. vol 24. issue 1. 2004-06-28. PMID:15049516. |
the effect of riluzole on l-[2,3-3h] glutamate uptake was investigated in rat cortical astrocyte cultures. |
2004-06-28 |
2023-08-12 |
rat |
| Cherif Boudaba, David M Linn, Katalin Cs Halmos, Jeffrey G Taske. Increased tonic activation of presynaptic metabotropic glutamate receptors in the rat supraoptic nucleus following chronic dehydration. The Journal of physiology. vol 551. issue Pt 3. 2004-05-27. PMID:12824445. |
increasing ambient glutamate levels by inhibiting astrocyte glutamate uptake resulted in a decrease in mepsc frequency due to increased activation of presynaptic mglurs. |
2004-05-27 |
2023-08-12 |
rat |
| Zhuying Wang, Gusta Trillo-Pazos, Seon-Young Kim, Mario Canki, Susan Morgello, Leroy R Sharer, Harris A Gelbard, Zao-Zhong Su, Dong-Chul Kang, Andrew I Brooks, Paul B Fisher, David J Volsk. Effects of human immunodeficiency virus type 1 on astrocyte gene expression and function: potential role in neuropathogenesis. Journal of neurovirology. vol 10 Suppl 1. 2004-05-10. PMID:14982736. |
focusing on a specific astrocyte function relevant to neuropathogenesis, the authors showed that exposure of astrocytes to hiv-1 or gp120 in vitro impairs the ability of the cells to transport l-glutamate and the authors related this defect to transcriptional inhibition of the eaat2 glutamate transporter gene. |
2004-05-10 |
2023-08-12 |
human |
| Nicholas J Maragakis, Joerg Dietrich, Victor Wong, Haipeng Xue, Margot Mayer-Proschel, Mahendra S Rao, Jeffrey D Rothstei. Glutamate transporter expression and function in human glial progenitors. Glia. vol 45. issue 2. 2004-04-30. PMID:14730707. |
eaat3 and eaat4 expression is reduced as glial maturation progresses both in astrocyte precursors and early-differentiated astrocytes and is consistent with their role in adult tissues as primarily neuronal glutamate transporters. |
2004-04-30 |
2023-08-12 |
human |
| Santina Bruzzone, Claudia Verderio, Ursula Schenk, Ernesto Fedele, Elena Zocchi, Michela Matteoli, Antonio De Flor. Glutamate-mediated overexpression of CD38 in astrocytes cultured with neurones. Journal of neurochemistry. vol 89. issue 1. 2004-04-26. PMID:15030411. |
the causal role of neurone-released glutamate in inducing overexpression of astrocyte cd38 is demonstrated by two observations: first, in the absence of neurones, induction of cd38 in pure astrocyte cultures can be obtained with glutamate and second, it can be prevented in co-cultures by glutamate receptor antagonists. |
2004-04-26 |
2023-08-12 |
Not clear |
| Giovanni Li Volti, Riccardo Ientile, Nader G Abraham, Angelo Vanella, Giuseppe Cannavò, Francesco Mazza, Monica Currò, Giuseppina Raciti, Roberto Avola, Agata Campis. Immunocytochemical localization and expression of heme oxygenase-1 in primary astroglial cell cultures during differentiation: effect of glutamate. Biochemical and biophysical research communications. vol 315. issue 2. 2004-04-20. PMID:14766239. |
immunocytochemical localization and expression of heme oxygenase-1 in primary astroglial cell cultures during differentiation: effect of glutamate. |
2004-04-20 |
2023-08-12 |
Not clear |
| M E S Frizzo, C Schwarzbold, L O Porciúncula, K B Dalcin, R B Rosa, C A J Ribeiro, D O Souza, M Wajne. 3-hydroxyglutaric acid enhances glutamate uptake into astrocytes from cerebral cortex of young rats. Neurochemistry international. vol 44. issue 5. 2004-02-02. PMID:14643752. |
although the exact mechanisms involved in 3-ohga-stimulatory effect on astrocyte glutamate uptake are unknown, the present findings contribute to the understanding of the pathophysiology of ga-i, suggesting that astrocytes may protect neurons against excitotoxic damage caused by 3-ohga by increasing glutamate uptake and therefore reducing the concentration of this excitatory neurotransmitter in the synaptic cleft. |
2004-02-02 |
2023-08-12 |
rat |
| Michael Wong, Kevin C Ess, Erik J Uhlmann, Laura A Jansen, Wen Li, Peter B Crino, Steven Mennerick, Kelvin A Yamada, David H Gutman. Impaired glial glutamate transport in a mouse tuberous sclerosis epilepsy model. Annals of neurology. vol 54. issue 2. 2004-01-05. PMID:12891680. |
electrophysiological assays demonstrate a functional decrease in glutamate transport currents of tsc1 cko astrocytes in hippocampal slices and astrocyte cultures. |
2004-01-05 |
2023-08-12 |
mouse |