| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C M Anderson, R J Bridges, A R Chamberlin, K Shimamoto, Y Yasuda-Kamatani, R A Swanso. Differing effects of substrate and non-substrate transport inhibitors on glutamate uptake reversal. Journal of neurochemistry. vol 79. issue 6. 2002-01-16. PMID:11752061. |
the present study assessed eaat inhibitors for their ability to inhibit glutamate uptake, act as transporter substrates and block uptake reversal in astrocyte and neuron cultures. |
2002-01-16 |
2023-08-12 |
Not clear |
| J Hammer, H Qu, A Håberg, U Sonnewal. In vivo effects of adenosine A(2) receptor agonist and antagonist on neuronal and astrocytic intermediary metabolism studied with ex vivo (13)C MR spectroscopy. Journal of neurochemistry. vol 79. issue 4. 2001-12-20. PMID:11723181. |
astrocyte metabolism was only affected in the cortex as shown by a decrease in the pyruvate carboxylase/pyruvate dehydrogenase ratio in glutamate and glutamine in the treatment groups. |
2001-12-20 |
2023-08-12 |
rat |
| H Akaoka, R Szymocha, P Beurton-Marduel, A Bernard, M F Belin, P Giraudo. Functional changes in astrocytes by human T-lymphotropic virus type-1 T-lymphocytes. Virus research. vol 78. issue 1-2. 2001-12-04. PMID:11520580. |
within the first week post-contact, an overall activation of astrocyte metabolism was observed as assessed by enhanced uptake of glutamate and glucose, and lactate release. |
2001-12-04 |
2023-08-12 |
human |
| R Daskalopoulos, J Korcok, P Farhangkhgoee, M Karmazyn, A W Gelb, J X Wilso. Propofol protection of sodium-hydrogen exchange activity sustains glutamate uptake during oxidative stress. Anesthesia and analgesia. vol 93. issue 5. 2001-12-04. PMID:11682397. |
exposure of primary astrocyte cultures to tert-butylhydroperoxide (t-booh, 300 microm) decreased the initial rate of na-dependent glutamate uptake. |
2001-12-04 |
2023-08-12 |
Not clear |
| M Zhou, H K Kimelber. Freshly isolated hippocampal CA1 astrocytes comprise two populations differing in glutamate transporter and AMPA receptor expression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 20. 2001-11-01. PMID:11588163. |
in the present study, we report that glutamate transporter (gt) currents can only be measured from one type of these freshly isolated hippocampal ca1 astrocytes [variably rectifying astrocytes (vras)] but were not detectable in the second type of astrocyte [outwardly rectifying astrocytes (oras)]. |
2001-11-01 |
2023-08-12 |
rat |
| A S Hazell, K V Rao, N C Danbolt, D V Pow, R F Butterwort. Selective down-regulation of the astrocyte glutamate transporters GLT-1 and GLAST within the medial thalamus in experimental Wernicke's encephalopathy. Journal of neurochemistry. vol 78. issue 3. 2001-08-30. PMID:11483659. |
selective down-regulation of the astrocyte glutamate transporters glt-1 and glast within the medial thalamus in experimental wernicke's encephalopathy. |
2001-08-30 |
2023-08-12 |
rat |
| A S Hazell, K V Rao, N C Danbolt, D V Pow, R F Butterwort. Selective down-regulation of the astrocyte glutamate transporters GLT-1 and GLAST within the medial thalamus in experimental Wernicke's encephalopathy. Journal of neurochemistry. vol 78. issue 3. 2001-08-30. PMID:11483659. |
treatment with pyrithiamine, a central thiamine antagonist, resulted in a 71 and 55% decrease in protein levels of the astrocyte glutamate transporters glt-1 and glast, respectively, by immunoblotting in the medial thalamus of day 14 symptomatic rats at loss of righting reflexes. |
2001-08-30 |
2023-08-12 |
rat |
| M E Frizzo, D R Lara, K C Dahm, A S Prokopiuk, R A Swanson, D O Souz. Activation of glutamate uptake by guanosine in primary astrocyte cultures. Neuroreport. vol 12. issue 4. 2001-08-02. PMID:11277601. |
activation of glutamate uptake by guanosine in primary astrocyte cultures. |
2001-08-02 |
2023-08-12 |
Not clear |
| Y Chen, N E Vartiainen, W Ying, P H Chan, J Koistinaho, R A Swanso. Astrocytes protect neurons from nitric oxide toxicity by a glutathione-dependent mechanism. Journal of neurochemistry. vol 77. issue 6. 2001-07-19. PMID:11413243. |
the presence of an astrocyte layer increased the ld(50) for glutamate by approximately four-fold, but had no effect on nmda toxicity. |
2001-07-19 |
2023-08-12 |
Not clear |
| P Bezzi, M Domercq, L Brambilla, R Galli, D Schols, E De Clercq, A Vescovi, G Bagetta, G Kollias, J Meldolesi, A Volterr. CXCR4-activated astrocyte glutamate release via TNFalpha: amplification by microglia triggers neurotoxicity. Nature neuroscience. vol 4. issue 7. 2001-07-19. PMID:11426226. |
cxcr4-activated astrocyte glutamate release via tnfalpha: amplification by microglia triggers neurotoxicity. |
2001-07-19 |
2023-08-12 |
Not clear |
| P Bezzi, M Domercq, L Brambilla, R Galli, D Schols, E De Clercq, A Vescovi, G Bagetta, G Kollias, J Meldolesi, A Volterr. CXCR4-activated astrocyte glutamate release via TNFalpha: amplification by microglia triggers neurotoxicity. Nature neuroscience. vol 4. issue 7. 2001-07-19. PMID:11426226. |
autocrine/paracrine tnfalpha-dependent signaling leading to prostaglandin (pg) formation not only controls glutamate release and astrocyte communication, but also causes their derangement when activated microglia cooperate to dramatically enhance release of the cytokine in response to cxcr4 stimulation. |
2001-07-19 |
2023-08-12 |
Not clear |
| V C Karpiak, R J Bridges, C L Eye. Organotins disrupt components of glutamate homeostasis in rat astrocyte cultures. Journal of toxicology and environmental health. Part A. vol 63. issue 4. 2001-07-19. PMID:11437060. |
organotins disrupt components of glutamate homeostasis in rat astrocyte cultures. |
2001-07-19 |
2023-08-12 |
rat |
| V C Karpiak, R J Bridges, C L Eye. Organotins disrupt components of glutamate homeostasis in rat astrocyte cultures. Journal of toxicology and environmental health. Part A. vol 63. issue 4. 2001-07-19. PMID:11437060. |
a rat cortical astrocyte preparation was used to investigate the effects of organotins on glutamate regulation by astrocytes. |
2001-07-19 |
2023-08-12 |
rat |
| W Cui, N D Allen, M Skynner, B Gusterson, A J Clar. Inducible ablation of astrocytes shows that these cells are required for neuronal survival in the adult brain. Glia. vol 34. issue 4. 2001-07-12. PMID:11360300. |
astrocyte ablation was associated with a dramatic decrease in the expression of glutamate transporters, which may account for the degeneration of granular neurons since the excitotoxic effects of glutamate result in a similar phenotype. |
2001-07-12 |
2023-08-12 |
mouse |
| L Peng, R A Swanson, L Hert. Effects of L-glutamate, D-aspartate, and monensin on glycolytic and oxidative glucose metabolism in mouse astrocyte cultures: further evidence that glutamate uptake is metabolically driven by oxidative metabolism. Neurochemistry international. vol 38. issue 5. 2001-06-21. PMID:11222924. |
effects of l-glutamate, d-aspartate, and monensin on glycolytic and oxidative glucose metabolism in mouse astrocyte cultures: further evidence that glutamate uptake is metabolically driven by oxidative metabolism. |
2001-06-21 |
2023-08-12 |
mouse |
| S M Hutson, E Lieth, K F LaNou. Function of leucine in excitatory neurotransmitter metabolism in the central nervous system. The Journal of nutrition. vol 131. issue 3. 2001-04-19. PMID:11238772. |
bcaa enter the astrocyte where transamination is catalyzed by bcatm, producing glutamate and branched-chain alpha-keto acids (bcka). |
2001-04-19 |
2023-08-12 |
Not clear |
| S M Hutson, E Lieth, K F LaNou. Function of leucine in excitatory neurotransmitter metabolism in the central nervous system. The Journal of nutrition. vol 131. issue 3. 2001-04-19. PMID:11238772. |
operation of the shuttle in the proposed direction provides a mechanism for efficient nitrogen transfer between astrocytes and neurons and synthesis of glutamate from astrocyte alpha-ketoglutarate. |
2001-04-19 |
2023-08-12 |
Not clear |
| K Abe, H Sait. Na+ and K+ dependence of L-glutamate-induced suppression of astrocyte stellation in culture. Biological & pharmaceutical bulletin. vol 24. issue 1. 2001-03-29. PMID:11201245. |
we have recently found that l-glutamate suppresses astrocyte stellation induced by various stimuli, and that this effect of l-glutamate is mimicked by transportable glutamate uptake inhibitors. |
2001-03-29 |
2023-08-12 |
rat |
| K Abe, H Sait. Na+ and K+ dependence of L-glutamate-induced suppression of astrocyte stellation in culture. Biological & pharmaceutical bulletin. vol 24. issue 1. 2001-03-29. PMID:11201245. |
to test the possible role of the glutamate transporter in the regulation of astrocyte morphology, we investigated the na+ and k+ dependence of this effect of l-glutamate. |
2001-03-29 |
2023-08-12 |
rat |
| K Abe, H Sait. Na+ and K+ dependence of L-glutamate-induced suppression of astrocyte stellation in culture. Biological & pharmaceutical bulletin. vol 24. issue 1. 2001-03-29. PMID:11201245. |
these results support that astrocyte morphology is affected by the activity of the na+ -dependent glutamate transporter. |
2001-03-29 |
2023-08-12 |
rat |