| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Diane B Ré, José Boucraut, Denise Samuel, Serge Birman, Lydia Kerkerian-Le Goff, Laurence Had-Aissoun. Glutamate transport alteration triggers differentiation-state selective oxidative death of cultured astrocytes: a mechanism different from excitotoxicity depending on intracellular GSH contents. Journal of neurochemistry. vol 85. issue 5. 2003-07-24. PMID:12753075. |
altogether, these data demonstrate that basal gsh content is a critical factor of astrocyte vulnerability to glutamate transport alteration with possible insights onto concurrent death of astrocytes and gliosis in neurodegenerative insults. |
2003-07-24 |
2023-08-12 |
rat |
| Marcos Emílio dos Santos Frizzo, Félix Alexandre Antunes Soares, Leonara Patrícia Dall'Onder, Diogo Rizzato Lara, Raymond A Swanson, Diogo Onofre Souz. Extracellular conversion of guanine-based purines to guanosine specifically enhances astrocyte glutamate uptake. Brain research. vol 972. issue 1-2. 2003-07-11. PMID:12711081. |
extracellular conversion of guanine-based purines to guanosine specifically enhances astrocyte glutamate uptake. |
2003-07-11 |
2023-08-12 |
Not clear |
| Marcos Emílio dos Santos Frizzo, Félix Alexandre Antunes Soares, Leonara Patrícia Dall'Onder, Diogo Rizzato Lara, Raymond A Swanson, Diogo Onofre Souz. Extracellular conversion of guanine-based purines to guanosine specifically enhances astrocyte glutamate uptake. Brain research. vol 972. issue 1-2. 2003-07-11. PMID:12711081. |
guanosine (guo) has been shown to stimulate glutamate uptake in primary astrocyte cultures. |
2003-07-11 |
2023-08-12 |
Not clear |
| Marcos Emílio dos Santos Frizzo, Félix Alexandre Antunes Soares, Leonara Patrícia Dall'Onder, Diogo Rizzato Lara, Raymond A Swanson, Diogo Onofre Souz. Extracellular conversion of guanine-based purines to guanosine specifically enhances astrocyte glutamate uptake. Brain research. vol 972. issue 1-2. 2003-07-11. PMID:12711081. |
these results point to specificity in the interaction between guo and the astrocyte glutamate uptake system. |
2003-07-11 |
2023-08-12 |
Not clear |
| Norbert Braun, Jean Sévigny, Santosh K Mishra, Simon C Robson, Stephan W Barth, Ruediger Gerstberger, Klaus Hammer, Herbert Zimmerman. Expression of the ecto-ATPase NTPDase2 in the germinal zones of the developing and adult rat brain. The European journal of neuroscience. vol 17. issue 7. 2003-06-20. PMID:12713638. |
double labelling for the astrocyte intermediate filament protein gfap and the glial glutamate transporter glast identifies the ntpdase2-positive cells as type-b cells. |
2003-06-20 |
2023-08-12 |
rat |
| Zu-Cheng Ye, Megan S Wyeth, Selva Baltan-Tekkok, Bruce R Ranso. Functional hemichannels in astrocytes: a novel mechanism of glutamate release. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 9. 2003-06-19. PMID:12736329. |
our results indicated that astrocyte hemichannels could influence cns levels of extracellular glutamate with implications for normal and pathological brain function. |
2003-06-19 |
2023-08-12 |
Not clear |
| Douglas L Rothman, Kevin L Behar, Fahmeed Hyder, Robert G Shulma. In vivo NMR studies of the glutamate neurotransmitter flux and neuroenergetics: implications for brain function. Annual review of physiology. vol 65. 2003-06-18. PMID:12524459. |
these (13)c mrs studies clearly demonstrate that glutamate released from presynaptic neurons is taken up by the astrocyte for subsequent glutamine synthesis. |
2003-06-18 |
2023-08-12 |
human |
| Caroline Rae, Nathan Hare, William A Bubb, Sally R McEwan, Angelika Bröer, James A McQuillan, Vladimir J Balcar, Arthur D Conigrave, Stefan Bröe. Inhibition of glutamine transport depletes glutamate and GABA neurotransmitter pools: further evidence for metabolic compartmentation. Journal of neurochemistry. vol 85. issue 2. 2003-05-14. PMID:12675927. |
the role of glutamine and alanine transport in the recycling of neurotransmitter glutamate was investigated in guinea pig brain cortical tissue slices and prisms, and in cultured neuroblastoma and astrocyte cell lines. |
2003-05-14 |
2023-08-12 |
Not clear |
| M Mateo Paz Soldán, Arthur E Warrington, Allan J Bieber, Bogoljub Ciric, Virginia Van Keulen, Larry R Pease, Moses Rodrigue. Remyelination-promoting antibodies activate distinct Ca2+ influx pathways in astrocytes and oligodendrocytes: relationship to the mechanism of myelin repair. Molecular and cellular neurosciences. vol 22. issue 1. 2003-04-21. PMID:12595235. |
astrocyte ca2+ signaling is mediated by a phospholipase c-dependent pathway while oligodendrocyte ca2+ signaling is mediated via ampa-sensitive glutamate receptors. |
2003-04-21 |
2023-08-12 |
mouse |
| Kazuho Abe, Miwa Misaw. Amyloid beta protein enhances the clearance of extracellular L-glutamate by cultured rat cortical astrocytes. Neuroscience research. vol 45. issue 1. 2003-04-08. PMID:12507721. |
to explore the impact of alzheimer's disease amyloid beta protein (abeta) on astrocyte functions, we investigated the effect of abeta on glutamate clearance capacity of cultured rat cortical astrocytes. |
2003-04-08 |
2023-08-12 |
rat |
| Micaela Zonta, Giorgio Carmignot. Calcium oscillations encoding neuron-to-astrocyte communication. Journal of physiology, Paris. vol 96. issue 3-4. 2003-04-04. PMID:12445896. |
the observation that the excitatory neurotransmitter glutamate released from presynaptic terminals can activate, beside the post-synaptic neuron, the glial cell astrocyte, stimulated glial cell research like no other event since the recognition in the 1980s that astrocytes can express on their membrane many receptors for classical neurotransmitters. |
2003-04-04 |
2023-08-12 |
Not clear |
| Laurence Had-Aissouni, Diane-Bérangère Ré, André Nieoullon, Lydia Kerkerian-Le Gof. Importance of astrocytic inactivation of synaptically released glutamate for cell survival in the central nervous system--are astrocytes vulnerable to low intracellular glutamate concentrations? Journal of physiology, Paris. vol 96. issue 3-4. 2003-04-04. PMID:12445912. |
inactivation of synaptically released glutamate is not only important for the phasic aspect of glutamatergic transmission but also for astrocyte metabolism, which supply neurons with different metabolic precursors, and for cell survival in the central nervous system. |
2003-04-04 |
2023-08-12 |
Not clear |
| Julian P Meeks, Steven Menneric. Feeding hungry neurons: astrocytes deliver food for thought. Neuron. vol 37. issue 2. 2003-04-04. PMID:12546812. |
provide evidence that astrocyte uptake of synaptic glutamate triggers astrocytic glycolysis and release of lactate, which in turn nourishes neurons and sustains neuronal activity. |
2003-04-04 |
2023-08-12 |
Not clear |
| Shumin Duan, Christopher M Anderson, Edmund C Keung, Yongmei Chen, Yiren Chen, Raymond A Swanso. P2X7 receptor-mediated release of excitatory amino acids from astrocytes. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 4. 2003-03-24. PMID:12598620. |
astrocyte glutamate release can modulate synaptic activity and participate in brain intercellular signaling. |
2003-03-24 |
2023-08-12 |
Not clear |
| Shumin Duan, Christopher M Anderson, Edmund C Keung, Yongmei Chen, Yiren Chen, Raymond A Swanso. P2X7 receptor-mediated release of excitatory amino acids from astrocytes. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 4. 2003-03-24. PMID:12598620. |
efflux through p2x7 channels is a previously unrecognized route of ligand-stimulated, nonvesicular astrocyte glutamate release. |
2003-03-24 |
2023-08-12 |
Not clear |
| Katja Matthias, Frank Kirchhoff, Gerald Seifert, Kerstin Hüttmann, Marina Matyash, Helmut Kettenmann, Christian Steinhäuse. Segregated expression of AMPA-type glutamate receptors and glutamate transporters defines distinct astrocyte populations in the mouse hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 5. 2003-03-24. PMID:12629179. |
segregated expression of ampa-type glutamate receptors and glutamate transporters defines distinct astrocyte populations in the mouse hippocampus. |
2003-03-24 |
2023-08-12 |
mouse |
| B I Juárez, M L Martínez, M Montante, L Dufour, E García, M E Jiménez-Capdevill. Methylmercury increases glutamate extracellular levels in frontal cortex of awake rats. Neurotoxicology and teratology. vol 24. issue 6. 2003-03-12. PMID:12460659. |
a current hypothesis about methylmercury (mehg) neurotoxicity proposes that neuronal damage is due to excitotoxicity following glutamate uptake alterations in the astrocyte. |
2003-03-12 |
2023-08-12 |
rat |
| Yongmei Chen, Raymond A Swanso. Astrocytes and brain injury. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 23. issue 2. 2003-03-12. PMID:12571445. |
astrocyte functions that are known to influence neuronal survival include glutamate uptake, glutamate release, free radical scavenging, water transport, and the production of cytokines and nitric oxide. |
2003-03-12 |
2023-08-12 |
Not clear |
| Tatiana Emanuelli, Fernanda W Pagel, Lisiane O Porciúncula, Diogo O Souz. Effects of 5-aminolevulinic acid on the glutamatergic neurotransmission. Neurochemistry international. vol 42. issue 2. 2003-01-21. PMID:12421591. |
the effects of ala on the [3h]glutamate and [3h]mk-801 (dizocilpine) binding to rat cortical membranes and on [3h]glutamate uptake by rat astrocyte cultures were evaluated in the present study in order to elucidate the interaction of ala with the glutamatergic system and its possible contribution to the in vivo excitatory properties of ala. ala (0-1mm) did not affect the binding of 100 nm [3h]glutamate, nor the equilibrium binding constants (k(d) and b(max)) of this neurotransmitter in rat or human cortical membranes. |
2003-01-21 |
2023-08-12 |
human |
| Tatiana Emanuelli, Fernanda W Pagel, Lisiane O Porciúncula, Diogo O Souz. Effects of 5-aminolevulinic acid on the glutamatergic neurotransmission. Neurochemistry international. vol 42. issue 2. 2003-01-21. PMID:12421591. |
ala (0-3mm) dose-dependently inhibited glutamate uptake by astrocyte cultures. |
2003-01-21 |
2023-08-12 |
human |