| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Daniela Caccamo, Agata Campisi, Herbert Marini, Elena B Adamo, Giovanni Li Volti, Francesco Squadrito, Riccardo Ientil. Glutamate promotes NF-kappaB pathway in primary astrocytes: protective effects of IRFI 016, a synthetic vitamin E analogue. Experimental neurology. vol 193. issue 2. 2005-07-15. PMID:15869940. |
a prolonged exposure to glutamate (24 h) caused a depletion of intracellular glutathione that, in astroglial cells, has been considered a biochemical change typical of early astrocyte dysfunction, leading to cell alterations occurring in the gliosis. |
2005-07-15 |
2023-08-12 |
Not clear |
| Daniela Caccamo, Agata Campisi, Herbert Marini, Elena B Adamo, Giovanni Li Volti, Francesco Squadrito, Riccardo Ientil. Glutamate promotes NF-kappaB pathway in primary astrocytes: protective effects of IRFI 016, a synthetic vitamin E analogue. Experimental neurology. vol 193. issue 2. 2005-07-15. PMID:15869940. |
altogether, these data confirm that gsh content plays a pivotal role to determine oxidative response to glutamate injury in primary astrocyte cultures and that nf-kappab pathway is involved in this response. |
2005-07-15 |
2023-08-12 |
Not clear |
| Ainara Vallejo-Illarramendi, Mónica Torres-Ramos, Marcello Melone, Fiorenzo Conti, Carlos Matut. Clozapine reduces GLT-1 expression and glutamate uptake in astrocyte cultures. Glia. vol 50. issue 3. 2005-06-30. PMID:15739191. |
clozapine reduces glt-1 expression and glutamate uptake in astrocyte cultures. |
2005-06-30 |
2023-08-12 |
Not clear |
| Ainara Vallejo-Illarramendi, Mónica Torres-Ramos, Marcello Melone, Fiorenzo Conti, Carlos Matut. Clozapine reduces GLT-1 expression and glutamate uptake in astrocyte cultures. Glia. vol 50. issue 3. 2005-06-30. PMID:15739191. |
to test the hypothesis that clozapine-induced reduction of glutamate transporter-1 (glt-1) expression is mediated by astrocytes, we studied the effects of clozapine on glu transporters and glu uptake in primary astrocyte cultures of the cerebral cortex. |
2005-06-30 |
2023-08-12 |
Not clear |
| Hai Chen, Dandan Su. The role of Na-K-Cl co-transporter in cerebral ischemia. Neurological research. vol 27. issue 3. 2005-06-13. PMID:15845211. |
our recent studies suggest that nkcc1 activation leads to high [k(+)](o(-)) induced astrocyte swelling and glutamate release, as well as neuronal na(+) , and cl(-) influx during acute excitotoxicity. |
2005-06-13 |
2023-08-12 |
Not clear |
| Chunlong Zhong, Xueren Zhao, Jayaprakash Sarva, Alan Kozikowski, Joseph H Neale, Bruce G Lyet. NAAG peptidase inhibitor reduces acute neuronal degeneration and astrocyte damage following lateral fluid percussion TBI in rats. Journal of neurotrauma. vol 22. issue 2. 2005-05-03. PMID:15716632. |
we conclude that the naag peptidase inhibitor zj-43 is a potential novel strategy to reduce both neuronal and astrocyte damage associated with the glutamate excitotoxicity after tbi. |
2005-05-03 |
2023-08-12 |
rat |
| E A Nagelhus, T M Mathiisen, O P Otterse. Aquaporin-4 in the central nervous system: cellular and subcellular distribution and coexpression with KIR4.1. Neuroscience. vol 129. issue 4. 2005-03-29. PMID:15561407. |
thus, immunogold analyses have revealed an enrichment of aqp4 in endfeet membranes in contact with brain microvessels or subarachnoidal space and a low but significant concentration in non-endfeet membranes, including those astrocyte membranes that ensheath glutamate synapses. |
2005-03-29 |
2023-08-12 |
Not clear |
| M Zink, A Schmitt, F A Henn, P Gas. Differential expression of glutamate transporters EAAT1 and EAAT2 in mice deficient for PACAP-type I receptor. Journal of neural transmission (Vienna, Austria : 1996). vol 111. issue 12. 2005-03-23. PMID:15565490. |
pituitary adenylate cyclase-activating polypeptide (pacap) modulates glutamatergic neurotransmission and induces the expression of glutamate transporters eaat1 and eaat2 in newborn mouse astroglial cell cultures. |
2005-03-23 |
2023-08-12 |
mouse |
| Weihai Ying, Conrad C Alano, Philippe Garnier, Raymond A Swanso. NAD+ as a metabolic link between DNA damage and cell death. Journal of neuroscience research. vol 79. issue 1-2. 2005-03-18. PMID:15562437. |
the addition of non-glucose substrates to the medium, pyruvate, glutamate, or glutamine, also prevented astrocyte death after parp-1 activation. |
2005-03-18 |
2023-08-12 |
mouse |
| Tatsuro Kumada, Akiko Hasegawa, Yasuno Iwasaki, Hiroko Baba, Kazuhiro Ikenak. Isolation of cystatin C via functional cloning of astrocyte differentiation factors. Developmental neuroscience. vol 26. issue 1. 2005-03-15. PMID:15509901. |
tgf-beta induced cysc and gfap expression in ap-16 cells, an astrocyte progenitor-like cell line expressing glast (a glutamate transporter subtype specifically expressed in immature astrocytes). |
2005-03-15 |
2023-08-12 |
mouse |
| Mathias Zink, Andrea Schmitt, Valentina Vengeliene, Fritz A Henn, Rainer Spanage. Ethanol induces expression of the glutamate transporters EAAT1 and EAAT2 in organotypic cortical slice cultures. Alcoholism, clinical and experimental research. vol 28. issue 11. 2005-03-01. PMID:15547463. |
thus, increased sensitivity of glutamate receptors and enhanced transmembrane transport of glutamate were found in primary astrocyte cultures. |
2005-03-01 |
2023-08-12 |
Not clear |
| Elaine Coleman, Robert Judd, Lori Hoe, John Dennis, Philip Posne. Effects of diabetes mellitus on astrocyte GFAP and glutamate transporters in the CNS. Glia. vol 48. issue 2. 2005-02-15. PMID:15378652. |
effects of diabetes mellitus on astrocyte gfap and glutamate transporters in the cns. |
2005-02-15 |
2023-08-12 |
rat |
| Elaine Coleman, Robert Judd, Lori Hoe, John Dennis, Philip Posne. Effects of diabetes mellitus on astrocyte GFAP and glutamate transporters in the CNS. Glia. vol 48. issue 2. 2005-02-15. PMID:15378652. |
we examined the effects of streptozotocin (stz)-induced diabetes in rats on the level of the astrocyte intermediate filament protein, glial fibrillary acidic protein (gfap), number of astrocytes, and levels of the astrocyte glutamate transporters, glutamate transporter-1 (glt-1) and glutamate/aspartate transporter (glast), in the cerebral cortex, hippocampus, and cerebellum by western blotting (wb) and immunohistochemistry (ih). |
2005-02-15 |
2023-08-12 |
rat |
| Elaine Coleman, Robert Judd, Lori Hoe, John Dennis, Philip Posne. Effects of diabetes mellitus on astrocyte GFAP and glutamate transporters in the CNS. Glia. vol 48. issue 2. 2005-02-15. PMID:15378652. |
no significant differences were noted in astrocyte glutamate transporter levels in the cerebral cortex, hippocampus, or cerebellum at either time period (wb, ih). |
2005-02-15 |
2023-08-12 |
rat |
| A Campisi, D Caccamo, G Li Volti, M Currò, G Parisi, R Avola, A Vanella, R Ientil. Glutamate-evoked redox state alterations are involved in tissue transglutaminase upregulation in primary astrocyte cultures. FEBS letters. vol 578. issue 1-2. 2005-02-15. PMID:15581620. |
these data suggest that tissue tgase upregulation may be part of a biochemical response to oxidative stress induced by a prolonged exposure of astrocyte cultures to glutamate. |
2005-02-15 |
2023-08-12 |
Not clear |
| Bala T S Susarla, Rebecca P Seal, Olga Zelenaia, Deborah J Watson, John H Wolfe, Susan G Amara, Michael B Robinso. Differential regulation of GLAST immunoreactivity and activity by protein kinase C: evidence for modification of amino and carboxyl termini. Journal of neurochemistry. vol 91. issue 5. 2005-02-10. PMID:15569258. |
in the present study, the effects of pkc activation on the glutamate aspartate transporter (glast) subtype of glutamate transporter were examined in primary astrocyte cultures. |
2005-02-10 |
2023-08-12 |
human |
| Angelika Bröer, Joachim W Deitmer, Stefan Bröe. Astroglial glutamine transport by system N is upregulated by glutamate. Glia. vol 48. issue 4. 2005-01-14. PMID:15390112. |
incubation of primary astrocyte cultures with physiological concentrations of glutamate resulted in a rapid, about twofold, upregulation of snat3-mediated transport activity. |
2005-01-14 |
2023-08-12 |
Not clear |
| Elfrida R Benjamin, Sarah L Haftl, Dimitris N Xanthos, Gregg Crumley, Mohamed Hachicha, Kenneth J Valenzan. A miniaturized column chromatography method for measuring receptor-mediated inositol phosphate accumulation. Journal of biomolecular screening. vol 9. issue 4. 2004-12-29. PMID:15191651. |
assay validation data for recombinant muscarinic receptor 1, galanin receptor 2, and rat astrocyte metabotropic glutamate receptor 5 are presented. |
2004-12-29 |
2023-08-12 |
rat |
| Marina Leite, Juliana K Frizzo, Patrícia Nardin, Lúcia Maria Vieira de Almeida, Francine Tramontina, Carmem Gottfried, Carlos-Alberto Gonçalve. Beta-hydroxy-butyrate alters the extracellular content of S100B in astrocyte cultures. Brain research bulletin. vol 64. issue 2. 2004-11-29. PMID:15342101. |
its effect upon s100b secretion, astrocyte morphology and glutamate uptake was particularly investigated. |
2004-11-29 |
2023-08-12 |
Not clear |
| Lisiane O Porciúncula, Tatiana Emanuelli, Rejane G Tavares, Carolina Schwarzbold, Marcos E S Frizzo, Diogo O Souza, Moacir Wajne. Glutaric acid stimulates glutamate binding and astrocytic uptake and inhibits vesicular glutamate uptake in forebrain from young rats. Neurochemistry international. vol 45. issue 7. 2004-11-09. PMID:15337307. |
finally, taken together these results and previous findings showing that ga markedly decreases synaptosomal glutamate uptake, it is possible that the stimulatory effect of ga on astrocyte glutamate uptake might indicate that astrocytes may protect neurons from excitotoxic damage caused by ga by increasing glutamate uptake and therefore reducing the concentration of this excitatory neurotransmitter in the synaptic cleft. |
2004-11-09 |
2023-08-12 |
rat |