| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sang Won Suh, Koji Aoyama, Conrad C Alano, Christopher M Anderson, Aaron M Hamby, Raymond A Swanso. Zinc inhibits astrocyte glutamate uptake by activation of poly(ADP-ribose) polymerase-1. Molecular medicine (Cambridge, Mass.). vol 13. issue 7-8. 2007-10-11. PMID:17728843. |
zinc inhibits astrocyte glutamate uptake by activation of poly(adp-ribose) polymerase-1. |
2007-10-11 |
2023-08-12 |
Not clear |
| Sang Won Suh, Koji Aoyama, Conrad C Alano, Christopher M Anderson, Aaron M Hamby, Raymond A Swanso. Zinc inhibits astrocyte glutamate uptake by activation of poly(ADP-ribose) polymerase-1. Molecular medicine (Cambridge, Mass.). vol 13. issue 7-8. 2007-10-11. PMID:17728843. |
in this study, cultured cortical astrocytes were used to explore the effects of zinc on astrocyte glutamate uptake, an energy-dependent process that is critical for neuron survival. |
2007-10-11 |
2023-08-12 |
Not clear |
| Kathleen C Somera-Molina, Beverley Robin, Cherie Ann Somera, Christopher Anderson, Christy Stine, Sookyong Koh, Heather A Behanna, Linda J Van Eldik, D Martin Watterson, Mark S Wainwrigh. Glial activation links early-life seizures and long-term neurologic dysfunction: evidence using a small molecule inhibitor of proinflammatory cytokine upregulation. Epilepsia. vol 48. issue 9. 2007-10-10. PMID:17521344. |
to determine the mechanisms by which glial activation may modulate neurologic injury, we examined both acute changes in proinflammatory cytokines and long-term changes in astrocyte and microglial activation and astrocyte glutamate transporters in a "two-hit" model of kainic acid (ka)-induced seizures. |
2007-10-10 |
2023-08-12 |
Not clear |
| Ludmila A Voloboueva, Sang Won Suh, Raymond A Swanson, Rona G Giffar. Inhibition of mitochondrial function in astrocytes: implications for neuroprotection. Journal of neurochemistry. vol 102. issue 4. 2007-10-04. PMID:17488276. |
using the mitochondrial inhibitor fluorocitrate (fc, 0.25 mmol/l) that is preferentially taken by astrocytes we found that inhibition of astrocyte mitochondria increased vulnerability of co-cultured neurons to glutamate toxicity. |
2007-10-04 |
2023-08-12 |
Not clear |
| Masami Takahashi, Makoto Itakura, Saori Yamamor. [Exocytotic release of signaling molecules from astrocytes]. Brain and nerve = Shinkei kenkyu no shinpo. vol 59. issue 7. 2007-09-14. PMID:17663140. |
recent accumulating evidences showed that astrocyte also release neurotransmitters and modulators such as glutamate, atp and d-serine. |
2007-09-14 |
2023-08-12 |
Not clear |
| Natalie A Prow, David N Iran. The opioid receptor antagonist, naloxone, protects spinal motor neurons in a murine model of alphavirus encephalomyelitis. Experimental neurology. vol 205. issue 2. 2007-07-10. PMID:17459376. |
finally, loss of glutamate transporter-1 (glt-1) expression in sc, an astrocyte glutamate reuptake protein responsible for lowering toxic extracellular levels of glutamate and preventing mn damage, was reversed by nal treatment. |
2007-07-10 |
2023-08-12 |
mouse |
| Natalie A Prow, David N Iran. The opioid receptor antagonist, naloxone, protects spinal motor neurons in a murine model of alphavirus encephalomyelitis. Experimental neurology. vol 205. issue 2. 2007-07-10. PMID:17459376. |
taken together, these data suggest that nal is neuroprotective in the sc by inhibiting microglial activation that, in turn, maintains normal astrocyte glutamate homeostasis. |
2007-07-10 |
2023-08-12 |
mouse |
| Julie Fotheringham, Donatella Donati, Nahid Akhyani, Anna Fogdell-Hahn, Alexander Vortmeyer, John D Heiss, Elizabeth Williams, Steven Weinstein, Derek A Bruce, William D Gaillard, Susumu Sato, William H Theodore, Steven Jacobso. Association of human herpesvirus-6B with mesial temporal lobe epilepsy. PLoS medicine. vol 4. issue 5. 2007-06-27. PMID:17535102. |
we sought, first, to determine the extent of hhv-6 infection in brain material resected from mtle and non-mtle patients; and second, to establish in vitro primary astrocyte cultures from freshly resected brain material and determine expression of glutamate transporters. |
2007-06-27 |
2023-08-12 |
human |
| Angelo Di Garbo, Michele Barbi, Santi Chillemi, Susanna Alloisio, Mario Nobil. Calcium signalling in astrocytes and modulation of neural activity. Bio Systems. vol 89. issue 1-3. 2007-06-26. PMID:17196325. |
then, the modulation effects on the neural dynamics arising from the release of glutamate from astrocyte are also investigated. |
2007-06-26 |
2023-08-12 |
Not clear |
| Renata Ciccarelli, Iolanda D'Alimonte, Patrizia Ballerini, Mariagrazia D'Auro, Eleonora Nargi, Silvana Buccella, Patrizia Di Iorio, Valeria Bruno, Ferdinando Nicoletti, Francesco Caciagl. Molecular signalling mediating the protective effect of A1 adenosine and mGlu3 metabotropic glutamate receptor activation against apoptosis by oxygen/glucose deprivation in cultured astrocytes. Molecular pharmacology. vol 71. issue 5. 2007-05-29. PMID:17293559. |
astrocyte death may occur in neurodegenerative disorders and complicates the outcome of brain ischemia, a condition associated with high extracellular levels of adenosine and glutamate. |
2007-05-29 |
2023-08-12 |
Not clear |
| Woo-Ping Ge, Shumin Dua. Persistent enhancement of neuron-glia signaling mediated by increased extracellular K+ accompanying long-term synaptic potentiation. Journal of neurophysiology. vol 97. issue 3. 2007-05-21. PMID:17035364. |
the increased k(+) accumulation and astrocyte depolarization after ltp induction may reduce the efficiency of glial glutamate transporters, which may contribute to the enhanced synaptic efficacy. |
2007-05-21 |
2023-08-12 |
Not clear |
| Yi-Bing Ouyang, Ludmila A Voloboueva, Li-Jun Xu, Rona G Giffar. Selective dysfunction of hippocampal CA1 astrocytes contributes to delayed neuronal damage after transient forebrain ischemia. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 16. 2007-05-07. PMID:17442809. |
in rats subjected to transient forebrain ischemia, ca1 astrocytes lose glutamate transport activity and immunoreactivity for gfap, s100beta, and glutamate transporter glt-1 within a few hours of reperfusion, but without astrocyte cell death. |
2007-05-07 |
2023-08-12 |
rat |
| Gavin Wright, Rajiv Jala. Management of hepatic encephalopathy in patients with cirrhosis. Best practice & research. Clinical gastroenterology. vol 21. issue 1. 2007-03-26. PMID:17223499. |
in the brain, the astrocyte is the main site for ammonia detoxification, during the conversion of glutamate to glutamine. |
2007-03-26 |
2023-08-12 |
Not clear |
| Srinivasan Kanumilli, Peter J Robert. Mechanisms of glutamate receptor induced proliferation of astrocytes. Neuroreport. vol 17. issue 18. 2007-03-19. PMID:17179862. |
activation of metabotropic glutamate receptor 5 with (s)-3,5-dihydroxyphenylglycine increased phospholipase d activity in astrocytes as well as astrocyte proliferation. |
2007-03-19 |
2023-08-12 |
Not clear |
| Srinivasan Kanumilli, Peter J Robert. Mechanisms of glutamate receptor induced proliferation of astrocytes. Neuroreport. vol 17. issue 18. 2007-03-19. PMID:17179862. |
activation of metabotropic glutamate receptor 3 with (2's,2'r,3'r)-2-(2',3'-dicarboxycyclopropyl)glycine-iv (dcg-iv) inhibited astrocyte proliferation without affecting metabotropic glutamate receptor 5-mediated phospholipase d activity. |
2007-03-19 |
2023-08-12 |
Not clear |
| Srinivasan Kanumilli, Peter J Robert. Mechanisms of glutamate receptor induced proliferation of astrocytes. Neuroreport. vol 17. issue 18. 2007-03-19. PMID:17179862. |
in conclusion, metabotropic glutamate receptor 5 stimulates astrocyte proliferation via a protein kinase c-phospholipase d-phosphatidic acid-dependent pathway, whereas metabotropic glutamate receptor 3-mediated inhibition of astrocyte proliferation does not involve phospholipase d, and is independent of metabotropic glutamate receptor 5-mediated effects. |
2007-03-19 |
2023-08-12 |
Not clear |
| Tamuna Lekishvili, Shirley Hesketh, Marcus W Brazier, David R Brow. Mouse galectin-1 inhibits the toxicity of glutamate by modifying NR1 NMDA receptor expression. The European journal of neuroscience. vol 24. issue 11. 2007-02-23. PMID:17156363. |
this form of cell death could arise from either excess levels of glutamate due to decreased astrocyte clearance or due to increased susceptibility. |
2007-02-23 |
2023-08-12 |
mouse |
| Ragunathan Padmashri, Sujit Kumar Sikda. Glutamate pretreatment affects Ca2+ signaling in processes of astrocyte pairs. Journal of neurochemistry. vol 100. issue 1. 2007-02-22. PMID:17059561. |
glutamate pretreatment affects ca2+ signaling in processes of astrocyte pairs. |
2007-02-22 |
2023-08-12 |
rat |
| Ragunathan Padmashri, Sujit Kumar Sikda. Glutamate pretreatment affects Ca2+ signaling in processes of astrocyte pairs. Journal of neurochemistry. vol 100. issue 1. 2007-02-22. PMID:17059561. |
estimation of local ca(2+) diffusion coefficients in the astrocytic processes indicated higher values in the adjoining astrocyte of the glutamate pretreated group. |
2007-02-22 |
2023-08-12 |
rat |
| Christel Genoud, Charles Quairiaux, Pascal Steiner, Harald Hirling, Egbert Welker, Graham W Knot. Plasticity of astrocytic coverage and glutamate transporter expression in adult mouse cortex. PLoS biology. vol 4. issue 11. 2007-01-31. PMID:17048987. |
this function of the astrocyte is dependent on its positioning around the synapse, as well as on the level of expression of its high-affinity glutamate transporters, glt1 and glast. |
2007-01-31 |
2023-08-12 |
mouse |