| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Manoj Kumar Mishra, Kanhaiya Lal Kumawat, Anirban Bas. Japanese encephalitis virus differentially modulates the induction of multiple pro-inflammatory mediators in human astrocytoma and astroglioma cell-lines. Cell biology international. vol 32. issue 12. 2009-01-09. PMID:18801452. |
the expression of different proteins such as astrocyte-specific glial fibrillary acidic protein (gfap), the glutamate aspartate transporter/essential amino acid transporter-1 (glast/eaat-1), glutamate transporter-1/essential amino acid transporter-2 (glt-1/eaat-2), ceruloplasmin and thioredoxin (trx) expression level also differ in different human astrocyte cell-lines following infection. |
2009-01-09 |
2023-08-12 |
human |
| Kaiyu Zheng, Annalisa Scimemi, Dmitri A Rusako. Receptor actions of synaptically released glutamate: the role of transporters on the scale from nanometers to microns. Biophysical journal. vol 95. issue 10. 2008-12-29. PMID:18689452. |
greater rises of glutamate occur only when <5% of transporters are available (for instance, when an astrocyte fails). |
2008-12-29 |
2023-08-12 |
human |
| Angelo C Lepore, Britta Rauck, Christine Dejea, Andrea C Pardo, Mahendra S Rao, Jeffrey D Rothstein, Nicholas J Maragaki. Focal transplantation-based astrocyte replacement is neuroprotective in a model of motor neuron disease. Nature neuroscience. vol 11. issue 11. 2008-12-19. PMID:18931666. |
neuroprotection was mediated in part by the primary astrocyte glutamate transporter glt1. |
2008-12-19 |
2023-08-12 |
human |
| Hannah E Boycott, Jenny A Wilkinson, John P Boyle, Hugh A Pearson, Chris Peer. Differential involvement of TNF alpha in hypoxic suppression of astrocyte glutamate transporters. Glia. vol 56. issue 9. 2008-11-12. PMID:18381653. |
differential involvement of tnf alpha in hypoxic suppression of astrocyte glutamate transporters. |
2008-11-12 |
2023-08-12 |
Not clear |
| Li-Ping Wang, Giselle Cheung, Golo Kronenberg, Karen Gertz, Shengbo Ji, Gerd Kempermann, Matthias Endres, Helmut Kettenman. Mild brain ischemia induces unique physiological properties in striatal astrocytes. Glia. vol 56. issue 9. 2008-11-12. PMID:18442086. |
under physiological conditions, two distinct populations of gfap-egfp cells could be identified: (1) brightly fluorescent cells had bushy processes, passive membrane properties, glutamate transporter activity, and high gap junction coupling rate typical for classical astrocytes; (2) weakly fluorescent cells were characterized by thin, clearly distinguishable processes, voltage-gated currents, complex responses to kainate, and low coupling rate reminiscent of an astrocyte subtype recently described in the hippocampus. |
2008-11-12 |
2023-08-12 |
mouse |
| U Lichter-Koneck. Profiling of astrocyte properties in the hyperammonaemic brain: shedding new light on the pathophysiology of the brain damage in hyperammonaemia. Journal of inherited metabolic disease. vol 31. issue 4. 2008-11-12. PMID:18683079. |
currently favoured hypotheses are astrocyte swelling due to increased intracellular glutamine content and neuronal cell death due to excitotoxicity caused by elevated extracellular glutamate levels. |
2008-11-12 |
2023-08-12 |
mouse |
| Morris H Baslo. The astrocyte surface NAAG receptor and NAAG peptidase signaling complex as a therapeutic target. Drug news & perspectives. vol 21. issue 5. 2008-10-23. PMID:18596989. |
naag is a peptide neurotransmitter released by stimulated neurons and specifically targeted to the group ii metabotropic glutamate receptor 3 (mglu(3)), activation of which initiates astrocyte ca(2+) waves responsible for astrocyte-astrocyte and astrocyte-vascular system signaling and induction of vascular hyperemic responses that increase energy supplies to stimulated neurons. |
2008-10-23 |
2023-08-12 |
human |
| Luciana Ferreira Romão, Vivian de Oliveira Sousa, Vivaldo Moura Neto, Flávia Carvalho Alcantara Gome. Glutamate activates GFAP gene promoter from cultured astrocytes through TGF-beta1 pathways. Journal of neurochemistry. vol 106. issue 2. 2008-09-16. PMID:18419760. |
here, we evaluated the role of the excitatory neurotransmitter, glutamate, in astrocyte differentiation. |
2008-09-16 |
2023-08-12 |
mouse |
| Luciana Ferreira Romão, Vivian de Oliveira Sousa, Vivaldo Moura Neto, Flávia Carvalho Alcantara Gome. Glutamate activates GFAP gene promoter from cultured astrocytes through TGF-beta1 pathways. Journal of neurochemistry. vol 106. issue 2. 2008-09-16. PMID:18419760. |
together, our results suggest that glial metabotropic glutamate 2/3 receptor activation by neurons induces tgf-beta1 secretion, leading to gfap gene activation and astrocyte differentiation and involves smad and mapk/pi3k pathways. |
2008-09-16 |
2023-08-12 |
mouse |
| Tammy Kielia. Glial connexins and gap junctions in CNS inflammation and disease. Journal of neurochemistry. vol 106. issue 3. 2008-09-15. PMID:18410504. |
of paramount importance to cns homeostasis are astrocyte networks formed by gap junctions, which play a critical role in maintaining the homeostatic regulation of extracellular ph, k+, and glutamate levels. |
2008-09-15 |
2023-08-12 |
Not clear |
| V L Tawfik, M R Regan, C Haenggeli, M L Lacroix-Fralish, N Nutile-McMenemy, N Perez, J D Rothstein, J A DeLe. Propentofylline-induced astrocyte modulation leads to alterations in glial glutamate promoter activation following spinal nerve transection. Neuroscience. vol 152. issue 4. 2008-08-07. PMID:18358622. |
propentofylline-induced astrocyte modulation leads to alterations in glial glutamate promoter activation following spinal nerve transection. |
2008-08-07 |
2023-08-12 |
mouse |
| Alessandra Swarowsky, Letícia Rodrigues, Regina Biasibetti, Marina C Leite, Lucas Fürstenau de Oliveira, Lucia M V de Almeida, Carmem Gottfried, Jorge A Quillfeldt, Matilde Achaval, Carlos-Alberto Gonçalve. Glial alterations in the hippocampus of rats submitted to ibotenic-induced lesion of the nucleus basalis magnocellularis. Behavioural brain research. vol 190. issue 2. 2008-07-30. PMID:18395808. |
in this study, we investigated possible specific astrocyte alterations in the hippocampi of wistar rats submitted to nbm damage with ibotenic acid, investigating the content and immunohistochemistry of glial fibrillary acidic protein (gfap), as well as s100b protein content, glutamate uptake and glutamine synthetase activity on the 7th and 28th post-lesion days. |
2008-07-30 |
2023-08-12 |
rat |
| Nuria de Vera, Emili Martínez, Coral Sanfeli. Spermine induces cell death in cultured human embryonic cerebral cortical neurons through N-methyl-D-aspartate receptor activation. Journal of neuroscience research. vol 86. issue 4. 2008-07-08. PMID:17941054. |
another effect observed is that glutamate, but not spermine, induced astrocyte swelling. |
2008-07-08 |
2023-08-12 |
human |
| James Schummers, Hongbo Yu, Mriganka Su. Tuned responses of astrocytes and their influence on hemodynamic signals in the visual cortex. Science (New York, N.Y.). vol 320. issue 5883. 2008-07-03. PMID:18566287. |
furthermore, blocking astrocyte glutamate transporters influenced the magnitude and duration of adjacent visually driven neuronal responses. |
2008-07-03 |
2023-08-12 |
Not clear |
| Wei Wang, Wen Wang, Yayun Wang, Jing Huang, Shengxi Wu, Yun-Qing L. Temporal changes of astrocyte activation and glutamate transporter-1 expression in the spinal cord after spinal nerve ligation-induced neuropathic pain. Anatomical record (Hoboken, N.J. : 2007). vol 291. issue 5. 2008-06-23. PMID:18384122. |
temporal changes of astrocyte activation and glutamate transporter-1 expression in the spinal cord after spinal nerve ligation-induced neuropathic pain. |
2008-06-23 |
2023-08-12 |
Not clear |
| Wei Wang, Wen Wang, Yayun Wang, Jing Huang, Shengxi Wu, Yun-Qing L. Temporal changes of astrocyte activation and glutamate transporter-1 expression in the spinal cord after spinal nerve ligation-induced neuropathic pain. Anatomical record (Hoboken, N.J. : 2007). vol 291. issue 5. 2008-06-23. PMID:18384122. |
as a glutamate scavenger, the glutamate transporter-1 (glt-1) is exclusively expressed on the astrocytes and probably correlates with astrocyte activation. |
2008-06-23 |
2023-08-12 |
Not clear |
| Renata T Abib, André Quincozes-Santos, Patricia Nardin, Susana T Wofchuk, Marcos L Perry, Carlos-Alberto Gonçalves, Carmem Gottfrie. Epicatechin gallate increases glutamate uptake and S100B secretion in C6 cell lineage. Molecular and cellular biochemistry. vol 310. issue 1-2. 2008-06-20. PMID:18066651. |
here, we evaluated cell morphology and integrity and specific astrocyte activities; glutamate uptake and secretion of s100b in the presence of 0.1, 1 and 10 microm ecg. |
2008-06-20 |
2023-08-12 |
Not clear |
| Eli Gunnarson, Marina Zelenina, Gustav Axehult, Yutong Song, Alexander Bondar, Patrik Krieger, Hjalmar Brismar, Sergey Zelenin, Anita Aperi. Identification of a molecular target for glutamate regulation of astrocyte water permeability. Glia. vol 56. issue 6. 2008-06-20. PMID:18286643. |
identification of a molecular target for glutamate regulation of astrocyte water permeability. |
2008-06-20 |
2023-08-12 |
rat |
| Eli Gunnarson, Marina Zelenina, Gustav Axehult, Yutong Song, Alexander Bondar, Patrik Krieger, Hjalmar Brismar, Sergey Zelenin, Anita Aperi. Identification of a molecular target for glutamate regulation of astrocyte water permeability. Glia. vol 56. issue 6. 2008-06-20. PMID:18286643. |
here, we report that glutamate increases astrocyte water permeability and that the molecular target for this effect is the aquaporin-4 (aqp4) serine 111 residue, which is in a strategic position for control of the water channel gating. |
2008-06-20 |
2023-08-12 |
rat |
| Jeremy Petravicz, Todd A Fiacco, Ken D McCarth. Loss of IP3 receptor-dependent Ca2+ increases in hippocampal astrocytes does not affect baseline CA1 pyramidal neuron synaptic activity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 19. 2008-06-13. PMID:18463250. |
astrocyte ca(2+) has been deemed necessary and sufficient to trigger the release of gliotransmitters, such as atp and glutamate, from astrocytes to modulate neuronal activity. |
2008-06-13 |
2023-08-12 |
mouse |