| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marta Navarrete, Alfonso Araqu. Endocannabinoids mediate neuron-astrocyte communication. Neuron. vol 57. issue 6. 2008-04-28. PMID:18367089. |
these receptors are activated by endocannabinoids released by neurons, increasing astrocyte ca2+ levels, which stimulate glutamate release that activates nmda receptors in pyramidal neurons. |
2008-04-28 |
2023-08-12 |
Not clear |
| R Padmashri, S K Sikda. Glutamate transporter blockade affects Ca(2+) responses in astrocytes. Neuroscience. vol 151. issue 1. 2008-04-22. PMID:18037246. |
to test the hypothesis we pretreated astrocytes in culture (primary rat astrocyte cultures) with glutamate (500 microm) and glutamate transport inhibitor, threo-beta-hydroxy-aspartate (200 microm, tbha) or glutamate (500 microm) in na(+) free extracellular solution for 20 min. |
2008-04-22 |
2023-08-12 |
rat |
| R Padmashri, S K Sikda. Glutamate transporter blockade affects Ca(2+) responses in astrocytes. Neuroscience. vol 151. issue 1. 2008-04-22. PMID:18037246. |
when the experiments were done on astrocyte pairs that were pretreated with glutamate and tbha, we observed attenuated ca(2+) responses in the adjoining cell when compared with the depolarized cell. |
2008-04-22 |
2023-08-12 |
rat |
| R Padmashri, S K Sikda. Glutamate transporter blockade affects Ca(2+) responses in astrocytes. Neuroscience. vol 151. issue 1. 2008-04-22. PMID:18037246. |
the results were contrary to our earlier observation of heightened responses in the adjoining cell of the astrocyte pair, in cells pretreated with glutamate alone. |
2008-04-22 |
2023-08-12 |
rat |
| Miguel Salazar, José Antonio Pariente, Ginés María Salido, Antonio Gonzále. Ebselen increases cytosolic free Ca2+ concentration, stimulates glutamate release and increases GFAP content in rat hippocampal astrocytes. Toxicology. vol 244. issue 2-3. 2008-04-09. PMID:18237838. |
our results show that ebselen (1-20microm) dose dependently increases [ca2+](c), stimulates glutamate release and increases gfap content, a hallmark of astrocyte reactivity. |
2008-04-09 |
2023-08-12 |
rat |
| Lúcia Maria Vieira de Almeida, Cristopher Celintano Piñeiro, Marina Concli Leite, Giovana Brolese, Rodrigo Bainy Leal, Carmem Gottfried, Carlos-Alberto Gonçalve. Protective effects of resveratrol on hydrogen peroxide induced toxicity in primary cortical astrocyte cultures. Neurochemical research. vol 33. issue 1. 2008-04-01. PMID:17594518. |
the aim of this study is to evaluate the putative protective effect of resveratrol against acute h2o2-induced oxidative stress in astrocyte cultures, evaluating ros production, glutamate uptake activity, glutathione content and s100b secretion. |
2008-04-01 |
2023-08-12 |
Not clear |
| Anlong Li, Qi Xi, Edward S Umstot, Lars Bellner, Michal L Schwartzman, Jonathan H Jaggar, Charles W Leffle. Astrocyte-derived CO is a diffusible messenger that mediates glutamate-induced cerebral arteriolar dilation by activating smooth muscle Cell KCa channels. Circulation research. vol 102. issue 2. 2008-03-27. PMID:17991880. |
brain slice arteriole dilation to glutamate was also blocked by l-2-alpha aminoadipic acid, a selective astrocyte toxin, and paxilline, a k(ca) channel blocker. |
2008-03-27 |
2023-08-12 |
Not clear |
| M R Bennett, L Farnell, W G Gibso. Origins of blood volume change due to glutamatergic synaptic activity at astrocytes abutting on arteriolar smooth muscle cells. Journal of theoretical biology. vol 250. issue 1. 2008-03-19. PMID:17920632. |
coupling from glutamatergic synapses to smooth muscle cells of arterioles is effected by astrocytes releasing epoxyeicosatrienoic acids (eets) onto them, following glutamate stimulation of the astrocyte. |
2008-03-19 |
2023-08-12 |
Not clear |
| Tore Eid, Anne Williamson, Tih-Shih W Lee, Ognen A Petroff, Nihal C de Laneroll. Glutamate and astrocytes--key players in human mesial temporal lobe epilepsy? Epilepsia. vol 49 Suppl 2. 2008-03-14. PMID:18226171. |
moreover, it appears that glial cells, particularly the astrocyte, may play a key role in the glutamate overflow in mtle. |
2008-03-14 |
2023-08-12 |
human |
| Yanrong Shi, Xiaoguang Liu, Debebe Gebremedhin, John R Falck, David R Harder, Raymond C Koehle. Interaction of mechanisms involving epoxyeicosatrienoic acids, adenosine receptors, and metabotropic glutamate receptors in neurovascular coupling in rat whisker barrel cortex. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 28. issue 1. 2008-03-10. PMID:17519974. |
adenosine, astrocyte metabotropic glutamate receptors (mglurs), and epoxyeicosatrienoic acids (eets) have been implicated in neurovascular coupling. |
2008-03-10 |
2023-08-12 |
rat |
| Lúcia Maria Vieira de Almeida, Cristopher Celintano Piñeiro, Marina Concli Leite, Giovanna Brolese, Francine Tramontina, Ana Maria Feoli, Carmen Gottfried, Carlos-Alberto Gonçalve. Resveratrol increases glutamate uptake, glutathione content, and S100B secretion in cortical astrocyte cultures. Cellular and molecular neurobiology. vol 27. issue 5. 2008-01-22. PMID:17554623. |
resveratrol increases glutamate uptake, glutathione content, and s100b secretion in cortical astrocyte cultures. |
2008-01-22 |
2023-08-12 |
rat |
| Lúcia Maria Vieira de Almeida, Cristopher Celintano Piñeiro, Marina Concli Leite, Giovanna Brolese, Francine Tramontina, Ana Maria Feoli, Carmen Gottfried, Carlos-Alberto Gonçalve. Resveratrol increases glutamate uptake, glutathione content, and S100B secretion in cortical astrocyte cultures. Cellular and molecular neurobiology. vol 27. issue 5. 2008-01-22. PMID:17554623. |
typical polygonal morphology becomes stellated when astrocyte cultures were exposed to 250 microm resveratrol for 24 h. at concentration of 25 microm, resveratrol was able to increase glutamate uptake and glutathione content. |
2008-01-22 |
2023-08-12 |
rat |
| Ling-Hui Zeng, Yannan Ouyang, Vered Gazit, John R Cirrito, Laura A Jansen, Kevin C Ess, Kelvin A Yamada, David F Wozniak, David M Holtzman, David H Gutmann, Michael Won. Abnormal glutamate homeostasis and impaired synaptic plasticity and learning in a mouse model of tuberous sclerosis complex. Neurobiology of disease. vol 28. issue 2. 2008-01-11. PMID:17714952. |
mice with inactivation of the tuberous sclerosis complex-1 (tsc1) gene in glia (tsc1 gfap cko mice) have deficient astrocyte glutamate transporters and develop seizures, suggesting that abnormal glutamate homeostasis contributes to neurological abnormalities in these mice. |
2008-01-11 |
2023-08-12 |
mouse |
| Hong Z Yin, Darryl T Tang, John H Weis. Intrathecal infusion of a Ca(2+)-permeable AMPA channel blocker slows loss of both motor neurons and of the astrocyte glutamate transporter, GLT-1 in a mutant SOD1 rat model of ALS. Experimental neurology. vol 207. issue 2. 2008-01-08. PMID:17719032. |
intrathecal infusion of a ca(2+)-permeable ampa channel blocker slows loss of both motor neurons and of the astrocyte glutamate transporter, glt-1 in a mutant sod1 rat model of als. |
2008-01-08 |
2023-08-12 |
rat |
| Elisabetta Daré, Gunnar Schulte, Olga Karovic, Christian Hammarberg, Bertil B Fredhol. Modulation of glial cell functions by adenosine receptors. Physiology & behavior. vol 92. issue 1-2. 2007-12-06. PMID:17574632. |
thus, in astrocytes adenosine receptors modulate inter alia glycogen metabolism, glutamate transporters, astrogliosis and astrocyte swelling. |
2007-12-06 |
2023-08-12 |
Not clear |
| Lucia Helena Martini, Fernanda Jung, Felix Antunes Soares, Liane Nanci Rotta, Deusa Aparecida Vendite, Marcos Emilio dos Santos Frizzo, Rosendo A Yunes, João Batista Calixto, Susana Wofchuk, Diogo O Souz. Naturally occurring compounds affect glutamatergic neurotransmission in rat brain. Neurochemical research. vol 32. issue 11. 2007-12-06. PMID:17577666. |
for this reason, in this study we investigated the effects of the hydroalcoholic extracts from drymis winteri (polygodial and drimanial), phyllanthus (rutin and quercetine), jathopha elliptica (jatrophone), hedyosmum brasiliense (13hds), ocotea suaveolens (tormentic acid), protium kleinii (alphabeta-amyrin), citrus paradise (naringin), soybean (genistein) and crataeva nurvala (lupeol), described as having antinociceptive effects, on glutamatergic transmission parameters, such as [(3)h]glutamate binding, [(3)h]glutamate uptake by synaptic vesicles and astrocyte cultures, and synaptosomal [(3)h]glutamate release. |
2007-12-06 |
2023-08-12 |
rat |
| Brenda L Bartnik, Stefan M Lee, David A Hovda, Richard L Sutto. The fate of glucose during the period of decreased metabolism after fluid percussion injury: a 13C NMR study. Journal of neurotrauma. vol 24. issue 7. 2007-11-29. PMID:17610349. |
a bilateral decrease in the 13c-labeling of both glutamate and glutamine was observed in the fpi rats at 3.5 h and the glutamine pool remained significantly decreased in the injured cortex at 24 h, suggesting reduced oxidative metabolism in both neuronal and astrocyte compartments after injury. |
2007-11-29 |
2023-08-12 |
rat |
| Hannah E Boycott, Mark Dallas, John P Boyle, Hugh A Pearson, Chris Peer. Hypoxia suppresses astrocyte glutamate transport independently of amyloid formation. Biochemical and biophysical research communications. vol 364. issue 1. 2007-11-26. PMID:17927959. |
hypoxia suppresses astrocyte glutamate transport independently of amyloid formation. |
2007-11-26 |
2023-08-12 |
Not clear |
| Michael P Hefferan, Karolina Kucharova, Kiyohiko Kinjo, Osamu Kakinohana, Gabriella Sekerkova, Seiya Nakamura, Tatsuya Fuchigami, Zoltan Tomori, Tony L Yaksh, Neil Kurtz, Martin Marsal. Spinal astrocyte glutamate receptor 1 overexpression after ischemic insult facilitates behavioral signs of spasticity and rigidity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 42. 2007-11-08. PMID:17942713. |
spinal astrocyte glutamate receptor 1 overexpression after ischemic insult facilitates behavioral signs of spasticity and rigidity. |
2007-11-08 |
2023-08-12 |
rat |
| Michael P Hefferan, Karolina Kucharova, Kiyohiko Kinjo, Osamu Kakinohana, Gabriella Sekerkova, Seiya Nakamura, Tatsuya Fuchigami, Zoltan Tomori, Tony L Yaksh, Neil Kurtz, Martin Marsal. Spinal astrocyte glutamate receptor 1 overexpression after ischemic insult facilitates behavioral signs of spasticity and rigidity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 42. 2007-11-08. PMID:17942713. |
treatment of rat astrocyte cultures with ampa led to dose-dependent glutamate release, an effect blocked by ngx424. |
2007-11-08 |
2023-08-12 |
rat |