| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Matos, E Augusto, C R Oliveira, P Agostinh. Amyloid-beta peptide decreases glutamate uptake in cultured astrocytes: involvement of oxidative stress and mitogen-activated protein kinase cascades. Neuroscience. vol 156. issue 4. 2009-04-14. PMID:18790019. |
therefore, the study of astrocyte responses to abeta, the main cellular type involved in the maintenance of synaptic glutamate concentrations, is crucial for understanding the pathogenesis of ad. |
2009-04-14 |
2023-08-12 |
rat |
| L H Bergersen, V Gunderse. Morphological evidence for vesicular glutamate release from astrocytes. Neuroscience. vol 158. issue 1. 2009-04-09. PMID:18479831. |
the astrocyte derived glutamate can in turn activate neuronal glutamate receptors, in particular n-methyl-d-aspartate (nmda) receptors. |
2009-04-09 |
2023-08-12 |
Not clear |
| André Quincozes-Santos, Larissa Daniele Bobermin, Juliana Kleinkauf-Rocha, Diogo Onofre Souza, Rudimar Riesgo, Carlos-Alberto Gonçalves, Carmem Gottfrie. Atypical neuroleptic risperidone modulates glial functions in C6 astroglial cells. Progress in neuro-psychopharmacology & biological psychiatry. vol 33. issue 1. 2009-04-02. PMID:19013209. |
considering the putative involvement of astroglial cells in neuropsychiatric disorders, we investigated the effect of risperidone on parameters of astrocyte activity - glutamate uptake, glutamine synthetase (gs) activity and glutathione (gsh) levels. |
2009-04-02 |
2023-08-12 |
Not clear |
| Stéphanie Goursaud, Elena N Kozlova, Jean-Marie Maloteaux, Emmanuel Herman. Cultured astrocytes derived from corpus callosum or cortical grey matter show distinct glutamate handling properties. Journal of neurochemistry. vol 108. issue 6. 2009-04-02. PMID:19222709. |
therefore, we have compared glutamate handling in astrocyte cultures derived from white matter (corpus callosum) and grey matter tissues (cortical structures). |
2009-04-02 |
2023-08-12 |
Not clear |
| Abraham Lemberg, María A Fernández, Carlos Coll, Diego O Rosello, Salvador Romay, Juan C Perazzo, Ester J Filinge. Reyes's syndrome, encephalopathy, hyperammonemia and acetyl salicylic acid ingestion in a city hospital of Buenos Aires, Argentina. Current drug safety. vol 4. issue 1. 2009-03-31. PMID:19149521. |
glutamate is an excitotoxic neurotransmitter, capable to produce neuron and astrocyte damage and apoptosis. |
2009-03-31 |
2023-08-12 |
Not clear |
| Ariane Zamoner, Luana Heimfarth, Regina Pessoa-Pureu. Congenital hypothyroidism is associated with intermediate filament misregulation, glutamate transporters down-regulation and MAPK activation in developing rat brain. Neurotoxicology. vol 29. issue 6. 2009-03-26. PMID:18845185. |
moreover, we verified the immunocontent of astrocyte glutamate/aspartate transporter (glast) and glutamate transporter-1 (glt-1) as well as activation of mitogen-activated protein kinases (mapks) in hypothyroid rats. |
2009-03-26 |
2023-08-12 |
rat |
| Maxwell R Bennett A . Stress and anxiety in schizophrenia and depression: glucocorticoids, corticotropin-releasing hormone and synapse regression. The Australian and New Zealand journal of psychiatry. vol 42. issue 12. 2009-02-27. PMID:19016087. |
in contrast, glucocorticoids, probably acting on nerve terminal and astrocyte grs, can release glutamate, so promoting nmda receptor activation. |
2009-02-27 |
2023-08-12 |
Not clear |
| Eli Gunnarson, Yutong Song, Jacob M Kowalewski, Hjalmar Brismar, Michael Brines, Anthony Cerami, Ulf Andersson, Marina Zelenina, Anita Aperi. Erythropoietin modulation of astrocyte water permeability as a component of neuroprotection. Proceedings of the National Academy of Sciences of the United States of America. vol 106. issue 5. 2009-02-27. PMID:19164545. |
recent studies from our laboratory have shown that glutamate, acting on group i metabotropic glutamate receptors (mglurs), increases the permeability of astrocyte aqp4, which, in situations of hypoxia-ischemia, will increase astrocyte water uptake. |
2009-02-27 |
2023-08-12 |
mouse |
| Chun Zhang Yang, Rui Zhao, Yan Dong, Xiao Qian Chen, Albert Cheung Hoi Y. Astrocyte and neuron intone through glutamate. Neurochemical research. vol 33. issue 12. 2009-02-19. PMID:18563562. |
astrocyte and neuron intone through glutamate. |
2009-02-19 |
2023-08-12 |
Not clear |
| Chun Zhang Yang, Rui Zhao, Yan Dong, Xiao Qian Chen, Albert Cheung Hoi Y. Astrocyte and neuron intone through glutamate. Neurochemical research. vol 33. issue 12. 2009-02-19. PMID:18563562. |
the unexpected finding of astrocytes to release glutamate as gliotransmitter challenges the traditional concepts on astrocyte being "passive" in cns communications. |
2009-02-19 |
2023-08-12 |
Not clear |
| Chun Zhang Yang, Rui Zhao, Yan Dong, Xiao Qian Chen, Albert Cheung Hoi Y. Astrocyte and neuron intone through glutamate. Neurochemical research. vol 33. issue 12. 2009-02-19. PMID:18563562. |
glutamate is the major excitatory transmitter in transferring information between neurons, but is now also known to activate astrocyte through transporters and receptors. |
2009-02-19 |
2023-08-12 |
Not clear |
| Yann Bernardinelli, Jean-Yves Chatto. Differential effects of glutamate transporter inhibitors on the global electrophysiological response of astrocytes to neuronal stimulation. Brain research. vol 1240. 2009-02-17. PMID:18823961. |
this result suggests that, in addition to inhibiting glutamate transport, dhk prevents astrocyte potassium uptake, possibly by blockade of inward-rectifier channels. |
2009-02-17 |
2023-08-12 |
rat |
| Marc Yudkoff, Yevgeny Daikhin, Oksana Horyn, Ilana Nissim, Itzhak Nissi. Ketosis and brain handling of glutamate, glutamine, and GABA. Epilepsia. vol 49 Suppl 8. 2009-01-22. PMID:19049594. |
according to this formulation, in ketotic brain astrocyte metabolism is more active, resulting in enhanced conversion of glutamate to glutamine. |
2009-01-22 |
2023-08-12 |
Not clear |
| Max R Bennett, Les Farnell, William G Gibso. A quantitative model of cortical spreading depression due to purinergic and gap-junction transmission in astrocyte networks. Biophysical journal. vol 95. issue 12. 2009-01-21. PMID:18952785. |
as a principal means of transmission between astrocytes is through their release of atp, we have investigated if a model in which sd is driven by the effects of astrocyte waves of atp interacting with waves of glutamate release from neurons and astrocytes can give a quantitative account of experimental observations on sd. |
2009-01-21 |
2023-08-12 |
Not clear |
| Manoj Kumar Mishra, Kanhaiya Lal Kumawat, Anirban Bas. Japanese encephalitis virus differentially modulates the induction of multiple pro-inflammatory mediators in human astrocytoma and astroglioma cell-lines. Cell biology international. vol 32. issue 12. 2009-01-09. PMID:18801452. |
the expression of different proteins such as astrocyte-specific glial fibrillary acidic protein (gfap), the glutamate aspartate transporter/essential amino acid transporter-1 (glast/eaat-1), glutamate transporter-1/essential amino acid transporter-2 (glt-1/eaat-2), ceruloplasmin and thioredoxin (trx) expression level also differ in different human astrocyte cell-lines following infection. |
2009-01-09 |
2023-08-12 |
human |
| Kaiyu Zheng, Annalisa Scimemi, Dmitri A Rusako. Receptor actions of synaptically released glutamate: the role of transporters on the scale from nanometers to microns. Biophysical journal. vol 95. issue 10. 2008-12-29. PMID:18689452. |
greater rises of glutamate occur only when <5% of transporters are available (for instance, when an astrocyte fails). |
2008-12-29 |
2023-08-12 |
human |
| Angelo C Lepore, Britta Rauck, Christine Dejea, Andrea C Pardo, Mahendra S Rao, Jeffrey D Rothstein, Nicholas J Maragaki. Focal transplantation-based astrocyte replacement is neuroprotective in a model of motor neuron disease. Nature neuroscience. vol 11. issue 11. 2008-12-19. PMID:18931666. |
neuroprotection was mediated in part by the primary astrocyte glutamate transporter glt1. |
2008-12-19 |
2023-08-12 |
human |
| Hannah E Boycott, Jenny A Wilkinson, John P Boyle, Hugh A Pearson, Chris Peer. Differential involvement of TNF alpha in hypoxic suppression of astrocyte glutamate transporters. Glia. vol 56. issue 9. 2008-11-12. PMID:18381653. |
differential involvement of tnf alpha in hypoxic suppression of astrocyte glutamate transporters. |
2008-11-12 |
2023-08-12 |
Not clear |
| Li-Ping Wang, Giselle Cheung, Golo Kronenberg, Karen Gertz, Shengbo Ji, Gerd Kempermann, Matthias Endres, Helmut Kettenman. Mild brain ischemia induces unique physiological properties in striatal astrocytes. Glia. vol 56. issue 9. 2008-11-12. PMID:18442086. |
under physiological conditions, two distinct populations of gfap-egfp cells could be identified: (1) brightly fluorescent cells had bushy processes, passive membrane properties, glutamate transporter activity, and high gap junction coupling rate typical for classical astrocytes; (2) weakly fluorescent cells were characterized by thin, clearly distinguishable processes, voltage-gated currents, complex responses to kainate, and low coupling rate reminiscent of an astrocyte subtype recently described in the hippocampus. |
2008-11-12 |
2023-08-12 |
mouse |
| U Lichter-Koneck. Profiling of astrocyte properties in the hyperammonaemic brain: shedding new light on the pathophysiology of the brain damage in hyperammonaemia. Journal of inherited metabolic disease. vol 31. issue 4. 2008-11-12. PMID:18683079. |
currently favoured hypotheses are astrocyte swelling due to increased intracellular glutamine content and neuronal cell death due to excitotoxicity caused by elevated extracellular glutamate levels. |
2008-11-12 |
2023-08-12 |
mouse |