| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pavel Katsel, William Byne, Panos Roussos, Weilun Tan, Larry Siever, Vahram Haroutunia. Astrocyte and glutamate markers in the superficial, deep, and white matter layers of the anterior cingulate gyrus in schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 36. issue 6. 2012-02-09. PMID:21270770. |
astrocyte and glutamate markers in the superficial, deep, and white matter layers of the anterior cingulate gyrus in schizophrenia. |
2012-02-09 |
2023-08-12 |
Not clear |
| Bing-xu Ren, Xiao-ping Gu, Ya-guo Zheng, Cheng-long Liu, Dan Wang, Yu-e Sun, Zheng-liang M. Intrathecal injection of metabotropic glutamate receptor subtype 3 and 5 agonist/antagonist attenuates bone cancer pain by inhibition of spinal astrocyte activation in a mouse model. Anesthesiology. vol 116. issue 1. 2012-02-06. PMID:22123524. |
intrathecal injection of metabotropic glutamate receptor subtype 3 and 5 agonist/antagonist attenuates bone cancer pain by inhibition of spinal astrocyte activation in a mouse model. |
2012-02-06 |
2023-08-12 |
mouse |
| Matthew Raymond, Peijun Li, Jean-Marie Mangin, Molly Huntsman, Vittorio Gall. Chronic perinatal hypoxia reduces glutamate-aspartate transporter function in astrocytes through the Janus kinase/signal transducer and activator of transcription pathway. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 49. 2012-02-02. PMID:22159101. |
our findings (1) demonstrate specific changes in astrocyte function after perinatal hypoxia, which might contribute to the particular pathogenesis of perinatal white matter injury, (2) provide evidence that at least part of these changes result from a disturbance of the jak/stat pathway by hypoxia, and (3) identify jak/stat signaling as a potential therapeutic target to restore normal glast expression and uptake of glutamate after perinatal brain injury. |
2012-02-02 |
2023-08-12 |
mouse |
| Claire-Marie Vacher, Valérie Grange-Messent, Ronald St-Louis, Danièle Raison, Jean-Marc Lacorte, Hélène Hardin-Pouze. Architecture of the hypothalamo-posthypophyseal complex is controlled by monoamines. Journal of neuroscience research. vol 89. issue 11. 2012-01-20. PMID:21805494. |
astrocytes showed a decrease in glutamate dehydrogenase (gdh) levels, whereas glutamine synthetase (gs) levels remained constant, suggesting a reduction in astrocyte glutamate catabolism. |
2012-01-20 |
2023-08-12 |
mouse |
| Juan A Orellana, Xavier F Figueroa, Helmuth A Sánchez, Susana Contreras-Duarte, Victoria Velarde, Juan C Sáe. Hemichannels in the neurovascular unit and white matter under normal and inflamed conditions. CNS & neurological disorders drug targets. vol 10. issue 3. 2012-01-11. PMID:21288190. |
however, if the stimulus is deleterious, microglia and the endothelium become overactivated, both releasing bioactive molecules (e.g., glutamate, cytokines, prostaglandins and atp) that increase the activity of astroglial hemichannels, reducing the astrocyte neuroprotective functions, and further reducing neuronal cell viability. |
2012-01-11 |
2023-08-12 |
Not clear |
| Anthony C Vernon, Edward J Smith, Lara Stevanato, Michel Mod. Selective activation of metabotropic glutamate receptor 7 induces inhibition of cellular proliferation and promotes astrocyte differentiation of ventral mesencephalon human neural stem/progenitor cells. Neurochemistry international. vol 59. issue 3. 2011-12-19. PMID:21624409. |
selective activation of metabotropic glutamate receptor 7 induces inhibition of cellular proliferation and promotes astrocyte differentiation of ventral mesencephalon human neural stem/progenitor cells. |
2011-12-19 |
2023-08-12 |
human |
| E V Stelmashook, N K Isaev, E R Lozier, E S Goryacheva, L G Khaspeko. Role of glutamine in neuronal survival and death during brain ischemia and hypoglycemia. The International journal of neuroscience. vol 121. issue 8. 2011-11-29. PMID:21574892. |
the analyzed data suggest that the constant maintenance of optimal concentrations and ratio of glutamine to glutamate in nerve tissue is not only critically important for the normal functioning of nervous system, but is also necessary for neuron and astrocyte viability. |
2011-11-29 |
2023-08-12 |
Not clear |
| Joice Stipursky, Luciana Romão, Vanessa Tortelli, Vivaldo Moura Neto, Flávia Carvalho Alcantara Gome. Neuron-glia signaling: Implications for astrocyte differentiation and synapse formation. Life sciences. vol 89. issue 15-16. 2011-11-15. PMID:21569780. |
further, we discuss the role of the excitatory neurotransmitter, glutamate and transforming growth factor beta 1 (tgf-β1) pathway in astrocyte generation and differentiation. |
2011-11-15 |
2023-08-12 |
Not clear |
| Hung-Yun Lin, Faith B Davis, Mary K Luidens, Shaker A Mousa, James H Cao, Min Zhou, Paul J Davi. Molecular basis for certain neuroprotective effects of thyroid hormone. Frontiers in molecular neuroscience. vol 4. 2011-11-10. PMID:22016721. |
thyroid hormone non-genomically stimulates astrocyte glutamate uptake, an action that protects both glial cells and neurons. |
2011-11-10 |
2023-08-12 |
Not clear |
| Aude Panatier, Joanne Vallée, Michael Haber, Keith K Murai, Jean-Claude Lacaille, Richard Robitaill. Astrocytes are endogenous regulators of basal transmission at central synapses. Cell. vol 146. issue 5. 2011-10-31. PMID:21855979. |
astrocyte activation occurs at functional compartments found along astrocytic processes and involves metabotropic glutamate subtype 5 receptors. |
2011-10-31 |
2023-08-12 |
Not clear |
| Monique Lavialle, Georg Aumann, Enrico Anlauf, Felicitas Pröls, Monique Arpin, Amin Derouich. Structural plasticity of perisynaptic astrocyte processes involves ezrin and metabotropic glutamate receptors. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 31. 2011-10-27. PMID:21753079. |
structural plasticity of perisynaptic astrocyte processes involves ezrin and metabotropic glutamate receptors. |
2011-10-27 |
2023-08-12 |
rat |
| Lyle W Ostrow, Thomas M Suchyna, Frederick Sach. Stretch induced endothelin-1 secretion by adult rat astrocytes involves calcium influx via stretch-activated ion channels (SACs). Biochemical and biophysical research communications. vol 410. issue 1. 2011-09-02. PMID:21640709. |
et-1, a potent vasoconstrictor, also inhibits the expression of astrocyte glutamate transporters and is mitogenic for astrocytes, glioma cells, neurons, and brain capillary endothelia. |
2011-09-02 |
2023-08-12 |
rat |
| Ling-Hui Zeng, Nicholas R Rensing, Bo Zhang, David H Gutmann, Michael J Gambello, Michael Won. Tsc2 gene inactivation causes a more severe epilepsy phenotype than Tsc1 inactivation in a mouse model of tuberous sclerosis complex. Human molecular genetics. vol 20. issue 3. 2011-07-19. PMID:21062901. |
similar to tsc1(gfap1)cko mice, tsc2(gfap1)cko mice exhibited epilepsy, premature death, progressive megencephaly, diffuse glial proliferation, dispersion of hippocampal pyramidal cells and decreased astrocyte glutamate transporter expression. |
2011-07-19 |
2023-08-12 |
mouse |
| Selva Baltan, Sean P Murphy, Camelia A Danilov, Amelia Bachleda, Richard S Morriso. Histone deacetylase inhibitors preserve white matter structure and function during ischemia by conserving ATP and reducing excitotoxicity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 11. 2011-06-15. PMID:21411642. |
this protection correlates with the upregulation of an astrocyte glutamate transporter, delayed and reduced glutamate accumulation during ogd, preservation of axonal mitochondria and oligodendrocytes, and maintenance of atp levels. |
2011-06-15 |
2023-08-12 |
mouse |
| Mirko Santello, Paola Bezzi, Andrea Volterr. TNFα controls glutamatergic gliotransmission in the hippocampal dentate gyrus. Neuron. vol 69. issue 5. 2011-05-11. PMID:21382557. |
with constitutive tnfα present, activation of astrocyte p2y1 receptors induces localized [ca(2+)](i) elevations followed by glutamate release and presynaptic nmda receptor-dependent synaptic potentiation. |
2011-05-11 |
2023-08-12 |
Not clear |
| V Bramanti, D Tomassoni, D Bronzi, S Grasso, M Currò, M Avitabile, G Li Volsi, M Renis, R Ientile, F Amenta, R Avol. Alpha-lipoic acid modulates GFAP, vimentin, nestin, cyclin D1 and MAP-kinase expression in astroglial cell cultures. Neurochemical research. vol 35. issue 12. 2011-04-28. PMID:20814740. |
in the present study, we evaluated the expression of some proliferation and differentiation markers in 15 div astrocyte cultures pretreated or not with 0.5 mm glutamate for 24 h and than maintained under chronic or acute treatment with 50 μm r(+)enantiomer or raceme alpha-lipoic acid (ala). |
2011-04-28 |
2023-08-12 |
Not clear |
| Dorte M Skytt, Karsten K Madsen, Kamilla Pajęcka, Arne Schousboe, Helle S Waagepeterse. Characterization of primary and secondary cultures of astrocytes prepared from mouse cerebral cortex. Neurochemical research. vol 35. issue 12. 2011-04-28. PMID:21127969. |
the cultures were characterized by immunostaining for the astrocyte markers glutamine synthetase (gs), glial fibrillary acidic protein, and the glutamate transporters eaat1 and eaat2. |
2011-04-28 |
2023-08-12 |
mouse |
| Hao Zhou, Qing Chen, Dan Li Kong, Jiang Guo, Qian Wang, Shou Yi Y. Effect of resveratrol on gliotransmitter levels and p38 activities in cultured astrocytes. Neurochemical research. vol 36. issue 1. 2011-04-18. PMID:20842424. |
the extracellular levels of glutamate, d-/l-serine and d-serine were apparently reduced by 100 μm resveratrol in control astrocyte cultures. |
2011-04-18 |
2023-08-12 |
Not clear |
| Angus M Brown, John Skamarauskas, Timothy Lister, Ameneh Madjd, David E Ra. Differential susceptibility of astrocytic and neuronal function to 3-chloropropanediol in the rat inferior colliculus. Journal of neurochemistry. vol 116. issue 6. 2011-04-15. PMID:21155803. |
to do this, we have developed an in vivo method for monitoring astrocyte function over time by giving hourly 20-min bolus challenge exposures to ammonia via an implanted microdialysis probe and measuring the resulting transient increases in the extracellular glutamine : glutamate ratio. |
2011-04-15 |
2023-08-12 |
rat |
| Dennis A Turner, David Cory Adamso. Neuronal-astrocyte metabolic interactions: understanding the transition into abnormal astrocytoma metabolism. Journal of neuropathology and experimental neurology. vol 70. issue 3. 2011-04-11. PMID:21293295. |
astrocyte functions include buffering the extracellular space, providing substrates to neurons, interchanging glutamate and glutamine for synaptic transmission with neurons, and facilitating access to blood vessels. |
2011-04-11 |
2023-08-12 |
Not clear |