| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B G Zhou, M D Norenber. Ammonia downregulates GLAST mRNA glutamate transporter in rat astrocyte cultures. Neuroscience letters. vol 276. issue 3. 2000-01-05. PMID:10612626. |
ammonia downregulates glast mrna glutamate transporter in rat astrocyte cultures. |
2000-01-05 |
2023-08-12 |
rat |
| B G Zhou, M D Norenber. Ammonia downregulates GLAST mRNA glutamate transporter in rat astrocyte cultures. Neuroscience letters. vol 276. issue 3. 2000-01-05. PMID:10612626. |
to extend these observations, we performed a northern blot analysis of the astroglial glutamate transporter glast (eaat1) in nh4cl-treated primary rat astrocyte cultures. |
2000-01-05 |
2023-08-12 |
rat |
| R Silva, L R Mata, S Gulbenkian, M A Brito, C Tiribelli, D Brite. Inhibition of glutamate uptake by unconjugated bilirubin in cultured cortical rat astrocytes: role of concentration and pH. Biochemical and biophysical research communications. vol 265. issue 1. 1999-12-17. PMID:10548492. |
these findings indicate that ucb, and more precisely the monoanionic species, impairs a crucial function of astrocytes such as glutamate transport and support a potential role of astrocyte function in the pathogenesis of ucb-related brain damage (kernicterus). |
1999-12-17 |
2023-08-12 |
rat |
| S Duan, C M Anderson, B A Stein, R A Swanso. Glutamate induces rapid upregulation of astrocyte glutamate transport and cell-surface expression of GLAST. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 23. 1999-12-17. PMID:10575016. |
glutamate induces rapid upregulation of astrocyte glutamate transport and cell-surface expression of glast. |
1999-12-17 |
2023-08-12 |
Not clear |
| S Duan, C M Anderson, B A Stein, R A Swanso. Glutamate induces rapid upregulation of astrocyte glutamate transport and cell-surface expression of GLAST. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 23. 1999-12-17. PMID:10575016. |
here, glutamate regulation of glutamate transport was studied using primary murine astrocyte cultures that express the glast (eaat1) and glt-1 (eaat2) transporter subtypes. |
1999-12-17 |
2023-08-12 |
Not clear |
| S Duan, C M Anderson, B A Stein, R A Swanso. Glutamate induces rapid upregulation of astrocyte glutamate transport and cell-surface expression of GLAST. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 23. 1999-12-17. PMID:10575016. |
biotinylation labeling of membrane surface proteins showed that glutamate incubation produced an increase in glast expression at the astrocyte cell surface. |
1999-12-17 |
2023-08-12 |
Not clear |
| S Duan, C M Anderson, B A Stein, R A Swanso. Glutamate induces rapid upregulation of astrocyte glutamate transport and cell-surface expression of GLAST. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 23. 1999-12-17. PMID:10575016. |
this feedback loop provides a mechanism by which changes in extracellular glutamate concentrations could rapidly modulate astrocyte glutamate transport capacity. |
1999-12-17 |
2023-08-12 |
Not clear |
| R P Sanzgiri, A Araque, P G Haydo. Prostaglandin E(2) stimulates glutamate receptor-dependent astrocyte neuromodulation in cultured hippocampal cells. Journal of neurobiology. vol 41. issue 2. 1999-11-26. PMID:10512979. |
prostaglandin e(2) stimulates glutamate receptor-dependent astrocyte neuromodulation in cultured hippocampal cells. |
1999-11-26 |
2023-08-12 |
rat |
| R P Sanzgiri, A Araque, P G Haydo. Prostaglandin E(2) stimulates glutamate receptor-dependent astrocyte neuromodulation in cultured hippocampal cells. Journal of neurobiology. vol 41. issue 2. 1999-11-26. PMID:10512979. |
this neuronal response required the presence of an astrocyte ca(2+) wave and was mediated through both n-methyl-d-aspartate (nmda) and non-nmda glutamate receptors. |
1999-11-26 |
2023-08-12 |
rat |
| R P Sanzgiri, A Araque, P G Haydo. Prostaglandin E(2) stimulates glutamate receptor-dependent astrocyte neuromodulation in cultured hippocampal cells. Journal of neurobiology. vol 41. issue 2. 1999-11-26. PMID:10512979. |
taken together with previous studies, these data demonstrate that pge(2)-evoked ca(2+) elevations in astrocyte cause the release of glutamate which activates neuronal ionotropic receptors. |
1999-11-26 |
2023-08-12 |
rat |
| M Fukaya, K Yamada, M Nagashima, K Tanaka, M Watanab. Down-regulated expression of glutamate transporter GLAST in Purkinje cell-associated astrocytes of reeler and weaver mutant cerebella. Neuroscience research. vol 34. issue 3. 1999-11-10. PMID:10515259. |
glutamate transporter glast is highly expressed in the bergmann glia (bg), a unipolar cerebellar astrocyte associated structurally and functionally with purkinje cells (pcs). |
1999-11-10 |
2023-08-12 |
Not clear |
| M C Longuemare, C R Rose, K Farrell, B R Ransom, S G Waxman, R A Swanso. K(+)-induced reversal of astrocyte glutamate uptake is limited by compensatory changes in intracellular Na+. Neuroscience. vol 93. issue 1. 1999-10-08. PMID:10430492. |
k(+)-induced reversal of astrocyte glutamate uptake is limited by compensatory changes in intracellular na+. |
1999-10-08 |
2023-08-12 |
Not clear |
| M C Longuemare, C R Rose, K Farrell, B R Ransom, S G Waxman, R A Swanso. K(+)-induced reversal of astrocyte glutamate uptake is limited by compensatory changes in intracellular Na+. Neuroscience. vol 93. issue 1. 1999-10-08. PMID:10430492. |
this possibility was examined using astrocyte cultures treated in two ways to reduce the driving force for glutamate uptake: incubation in high k+ (with reciprocal reduction in na+), and incubation with metabolic inhibitors to induce atp depletion. |
1999-10-08 |
2023-08-12 |
Not clear |
| P J Magistretti, L Pelleri. Cellular mechanisms of brain energy metabolism and their relevance to functional brain imaging. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 354. issue 1387. 1999-10-04. PMID:10466143. |
the stoichiometry of this process is such that for one glutamate molecule taken up with three na+ ions, one glucose molecule enters an astrocyte, two atp molecules are produced through aerobic glycolysis and two lactate molecules are released. |
1999-10-04 |
2023-08-12 |
Not clear |
| P J Magistretti, L Pelleri. Cellular mechanisms of brain energy metabolism and their relevance to functional brain imaging. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 354. issue 1387. 1999-10-04. PMID:10466143. |
within the astrocyte, one atp molecule fuels one 'turn of the pump' while the other provides the energy needed to convert glutamate to glutamine by glutamine synthase. |
1999-10-04 |
2023-08-12 |
Not clear |
| D B Stanimirovic, R Ball, D L Small, A Murugananda. Developmental regulation of glutamate transporters and glutamine synthetase activity in astrocyte cultures differentiated in vitro. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 17. issue 3. 1999-09-30. PMID:10452361. |
developmental regulation of glutamate transporters and glutamine synthetase activity in astrocyte cultures differentiated in vitro. |
1999-09-30 |
2023-08-12 |
rat |
| D B Stanimirovic, R Ball, D L Small, A Murugananda. Developmental regulation of glutamate transporters and glutamine synthetase activity in astrocyte cultures differentiated in vitro. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 17. issue 3. 1999-09-30. PMID:10452361. |
the differences in expression/inducibility of glutamate transporters and glutamine synthetase observed in astrocyte cultures derived from various stages of fetal and postnatal development suggest that astrocytes in vivo might also respond differently to environmental or injurious stimuli during development and maturation. |
1999-09-30 |
2023-08-12 |
rat |
| C P Holden, N J Haughey, A Nath, J D Geige. Role of Na+/H+ exchangers, excitatory amino acid receptors and voltage-operated Ca2+ channels in human immunodeficiency virus type 1 gp120-mediated increases in intracellular Ca2+ in human neurons and astrocytes. Neuroscience. vol 91. issue 4. 1999-08-24. PMID:10391443. |
gp120 appears to activate astrocyte na+/h+ exchangers to release glutamate and potassium and, subsequent to this, increases in [ca2+]i in neurons and astrocytes result from activation of excitatory amino acid receptors on astrocytes and neurons, and voltage-operated calcium channels on neurons. |
1999-08-24 |
2023-08-12 |
human |
| F J Northington, R J Traystman, R C Koehler, L J Marti. GLT1, glial glutamate transporter, is transiently expressed in neurons and develops astrocyte specificity only after midgestation in the ovine fetal brain. Journal of neurobiology. vol 39. issue 4. 1999-07-28. PMID:10380073. |
glt1, glial glutamate transporter, is transiently expressed in neurons and develops astrocyte specificity only after midgestation in the ovine fetal brain. |
1999-07-28 |
2023-08-12 |
Not clear |
| G A Silva, E Theriault, L R Mills, P S Pennefather, C J Feene. Group I and II metabotropic glutamate receptor expression in cultured rat spinal cord astrocytes. Neuroscience letters. vol 263. issue 2-3. 1999-06-10. PMID:10213149. |
we have examined the development of expression of group i and ii metabotropic glutamate receptors (mglurs) in pure rat spinal cord astrocyte cultures, using immunocytological and calcium imaging techniques. |
1999-06-10 |
2023-08-12 |
rat |