| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Susan L Campbell, John J Hablitz, Michelle L Olse. Functional changes in glutamate transporters and astrocyte biophysical properties in a rodent model of focal cortical dysplasia. Frontiers in cellular neuroscience. vol 8. 2015-01-08. PMID:25565960. |
astrocyte glutamate transporters play a pivotal role in cortical maintaining extracellular glutamate concentrations. |
2015-01-08 |
2023-08-13 |
rat |
| Susan L Campbell, John J Hablitz, Michelle L Olse. Functional changes in glutamate transporters and astrocyte biophysical properties in a rodent model of focal cortical dysplasia. Frontiers in cellular neuroscience. vol 8. 2015-01-08. PMID:25565960. |
astrocyte glutamate transporter currents from lesioned animals were also significantly reduced when challenged exogenously applied glutamate. |
2015-01-08 |
2023-08-13 |
rat |
| Junnan Xu, Dan Song, Qiufang Bai, Lijun Zhou, Liping Cai, Leif Hertz, Liang Pen. Role of glycogenolysis in stimulation of ATP release from cultured mouse astrocytes by transmitters and high K+ concentrations. ASN neuro. vol 6. issue 1. 2014-12-23. PMID:24328680. |
the present study has confirmed and quantitated stimulated atp release from well differentiated astrocyte cultures by glutamate, adenosine or elevated extracellular k+ concentrations, measured by a luciferin/luciferase reaction. |
2014-12-23 |
2023-08-12 |
mouse |
| Akira Yamashita, Asami Hamada, Yuki Suhara, Rui Kawabe, Makoto Yanase, Naoko Kuzumaki, Michiko Narita, Ryosuke Matsui, Hideyuki Okano, Minoru Narit. Astrocytic activation in the anterior cingulate cortex is critical for sleep disorder under neuropathic pain. Synapse (New York, N.Y.). vol 68. issue 6. 2014-11-28. PMID:24488840. |
furthermore, glutamate induced the translocation of gat-3 to astrocyte cell membranes using primary cultured glial cells from the mouse cortex. |
2014-11-28 |
2023-08-12 |
mouse |
| Kenji Ono, Hiromi Suzuki, Madoka Higa, Kaori Tabata, Makoto Sawad. Glutamate release from astrocyte cell-line GL261 via alterations in the intracellular ion environment. Journal of neural transmission (Vienna, Austria : 1996). vol 121. issue 3. 2014-10-14. PMID:24100416. |
glutamate release from astrocyte cell-line gl261 via alterations in the intracellular ion environment. |
2014-10-14 |
2023-08-12 |
Not clear |
| Christopher I Ugbode, Warren D Hirst, Marcus Rattra. Neuronal influences are necessary to produce mitochondrial co-localization with glutamate transporters in astrocytes. Journal of neurochemistry. vol 130. issue 5. 2014-10-14. PMID:24814819. |
recent evidence suggests that the predominant astrocyte glutamate transporter, glt-1/ excitatory amino acid transporter 2 (eaat2) is associated with mitochondria. |
2014-10-14 |
2023-08-13 |
mouse |
| Moritz Armbruster, David Hampton, Yongjie Yang, Chris G Dull. Laser-scanning astrocyte mapping reveals increased glutamate-responsive domain size and disrupted maturation of glutamate uptake following neonatal cortical freeze-lesion. Frontiers in cellular neuroscience. vol 8. 2014-09-24. PMID:25249939. |
laser-scanning astrocyte mapping reveals increased glutamate-responsive domain size and disrupted maturation of glutamate uptake following neonatal cortical freeze-lesion. |
2014-09-24 |
2023-08-13 |
Not clear |
| Moritz Armbruster, David Hampton, Yongjie Yang, Chris G Dull. Laser-scanning astrocyte mapping reveals increased glutamate-responsive domain size and disrupted maturation of glutamate uptake following neonatal cortical freeze-lesion. Frontiers in cellular neuroscience. vol 8. 2014-09-24. PMID:25249939. |
to probe astrocyte glutamate transport with better spatial precision we have developed a novel technique, laser scanning astrocyte mapping (lsam), which combines glutamate transport current (tc) recording from astrocytes with laser scanning glutamate photolysis. |
2014-09-24 |
2023-08-13 |
Not clear |
| Moritz Armbruster, David Hampton, Yongjie Yang, Chris G Dull. Laser-scanning astrocyte mapping reveals increased glutamate-responsive domain size and disrupted maturation of glutamate uptake following neonatal cortical freeze-lesion. Frontiers in cellular neuroscience. vol 8. 2014-09-24. PMID:25249939. |
lsam allows us to identify the area from which a single astrocyte can transport glutamate and to quantify spatial heterogeneity in the rate of glutamate clearance kinetics within that domain. |
2014-09-24 |
2023-08-13 |
Not clear |
| Moritz Armbruster, David Hampton, Yongjie Yang, Chris G Dull. Laser-scanning astrocyte mapping reveals increased glutamate-responsive domain size and disrupted maturation of glutamate uptake following neonatal cortical freeze-lesion. Frontiers in cellular neuroscience. vol 8. 2014-09-24. PMID:25249939. |
these findings introduce a novel method to probe astrocyte glutamate uptake and show that neonatal cortical fl disrupts the functional maturation of cortical astrocytes. |
2014-09-24 |
2023-08-13 |
Not clear |
| Pei-Sen Yao, De-Zhi Kang, Ru-Ying Lin, Bing Ye, Wei Wang, Zu-Cheng Y. Glutamate/glutamine metabolism coupling between astrocytes and glioma cells: neuroprotection and inhibition of glioma growth. Biochemical and biophysical research communications. vol 450. issue 1. 2014-09-21. PMID:24944014. |
(2) glutamate levels in cgas were directly determined by the astrocyte/glioma ratios, indicating a balance between glioma glutamate release and astrocyte glutamate uptake. |
2014-09-21 |
2023-08-13 |
Not clear |
| Christopher F Rose, Alexei Verkhratsky, Vladimir Parpur. Astrocyte glutamine synthetase: pivotal in health and disease. Biochemical Society transactions. vol 41. issue 6. 2014-08-29. PMID:24256247. |
gs plays a pivotal role in glutamate and glutamine homoeostasis, orchestrating astrocyte glutamate uptake/release and the glutamate-glutamine cycle. |
2014-08-29 |
2023-08-12 |
Not clear |
| Ke Li, Charles Nicaise, Daniel Sannie, Tamara J Hala, Elham Javed, Jessica L Parker, Rajarshi Putatunda, Kathleen A Regan, Valérie Suain, Jean-Pierre Brion, Fred Rhoderick, Megan C Wright, David J Poulsen, Angelo C Lepor. Overexpression of the astrocyte glutamate transporter GLT1 exacerbates phrenic motor neuron degeneration, diaphragm compromise, and forelimb motor dysfunction following cervical contusion spinal cord injury. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 22. 2014-08-05. PMID:24872566. |
overexpression of the astrocyte glutamate transporter glt1 exacerbates phrenic motor neuron degeneration, diaphragm compromise, and forelimb motor dysfunction following cervical contusion spinal cord injury. |
2014-08-05 |
2023-08-13 |
mouse |
| Hyungju Park, Kyung-Seok Han, Soo-Jin Oh, Seonmi Jo, Junsung Woo, Bo-Eun Yoon, C Justin Le. High glutamate permeability and distal localization of Best1 channel in CA1 hippocampal astrocyte. Molecular brain. vol 6. 2014-07-15. PMID:24321245. |
high glutamate permeability and distal localization of best1 channel in ca1 hippocampal astrocyte. |
2014-07-15 |
2023-08-12 |
mouse |
| Hyungju Park, Kyung-Seok Han, Soo-Jin Oh, Seonmi Jo, Junsung Woo, Bo-Eun Yoon, C Justin Le. High glutamate permeability and distal localization of Best1 channel in CA1 hippocampal astrocyte. Molecular brain. vol 6. 2014-07-15. PMID:24321245. |
in particular, we have characterized a glutamate-permeable ca2+-activated anion channel encoded by bestrophin 1 gene (best1) that is responsible for ca2+-dependent, channel-mediated glutamate release in astrocyte. |
2014-07-15 |
2023-08-12 |
mouse |
| Oscar P Dall'Igna, Larissa D Bobermin, Diogo O Souza, André Quincozes-Santo. Riluzole increases glutamate uptake by cultured C6 astroglial cells. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 31. issue 7. 2014-06-27. PMID:23777615. |
here, we demonstrate that riluzole stimulated glutamate uptake and augmented the expression of the glutamate eaac1 transporter in c6 astroglial cell cultures. |
2014-06-27 |
2023-08-12 |
Not clear |
| Tore Eid, Nathan Tu, Tih-Shih W Lee, James C K La. Regulation of astrocyte glutamine synthetase in epilepsy. Neurochemistry international. vol 63. issue 7. 2014-06-23. PMID:23791709. |
the known stoichiometry of glutamate transport across the astrocyte plasma membrane also suggests that rapid metabolism of intracellular glutamate via gs is a prerequisite for efficient glutamate clearance from the extracellular space. |
2014-06-23 |
2023-08-12 |
Not clear |
| Glenn T Konopaske, Nicolas R Bolo, Alo C Basu, Perry F Renshaw, Joseph T Coyl. Time-dependent effects of haloperidol on glutamine and GABA homeostasis and astrocyte activity in the rat brain. Psychopharmacology. vol 230. issue 1. 2014-06-10. PMID:23660600. |
since astrocytes play a key role in glutamate metabolism, chronic haloperidol administration was hypothesized to modulate astrocyte metabolic function and glutamate homeostasis. |
2014-06-10 |
2023-08-12 |
rat |
| Martin D Haustein, Sebastian Kracun, Xiao-Hong Lu, Tiffany Shih, Olan Jackson-Weaver, Xiaoping Tong, Ji Xu, X William Yang, Thomas J O'Dell, Jonathan S Marvin, Mark H Ellisman, Eric A Bushong, Loren L Looger, Baljit S Khak. Conditions and constraints for astrocyte calcium signaling in the hippocampal mossy fiber pathway. Neuron. vol 82. issue 2. 2014-06-05. PMID:24742463. |
we used genetically encoded ca²⁺ and glutamate indicators as well as pharmacogenetic and electrical control of neurotransmitter release to explore astrocyte activity in the hippocampal mossy fiber pathway. |
2014-06-05 |
2023-08-13 |
Not clear |
| Martin D Haustein, Sebastian Kracun, Xiao-Hong Lu, Tiffany Shih, Olan Jackson-Weaver, Xiaoping Tong, Ji Xu, X William Yang, Thomas J O'Dell, Jonathan S Marvin, Mark H Ellisman, Eric A Bushong, Loren L Looger, Baljit S Khak. Conditions and constraints for astrocyte calcium signaling in the hippocampal mossy fiber pathway. Neuron. vol 82. issue 2. 2014-06-05. PMID:24742463. |
our data revealed numerous localized, spontaneous ca²⁺ signals in astrocyte branches and territories, but these were not driven by neuronal activity or glutamate. |
2014-06-05 |
2023-08-13 |
Not clear |