| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhi Zhang, Bassam Bassam, Ajit G Thomas, Monica Williams, Jinhuan Liu, Elizabeth Nance, Camilo Rojas, Barbara S Slusher, Sujatha Kanna. Maternal inflammation leads to impaired glutamate homeostasis and up-regulation of glutamate carboxypeptidase II in activated microglia in the fetal/newborn rabbit brain. Neurobiology of disease. vol 94. 2018-02-27. PMID:27326668. |
in this study, we assessed the effect of maternal inflammation on key components of the glutamate pathway and its relationship to astrocyte and microglial activation in the fetal and neonatal new zealand white rabbit brain. |
2018-02-27 |
2023-08-13 |
rabbit |
| Zhi Zhang, Bassam Bassam, Ajit G Thomas, Monica Williams, Jinhuan Liu, Elizabeth Nance, Camilo Rojas, Barbara S Slusher, Sujatha Kanna. Maternal inflammation leads to impaired glutamate homeostasis and up-regulation of glutamate carboxypeptidase II in activated microglia in the fetal/newborn rabbit brain. Neurobiology of disease. vol 94. 2018-02-27. PMID:27326668. |
these results suggest that maternal intrauterine endotoxin exposure results in early onset and long-lasting dysregulation of glutamate homeostasis, which may be mediated by impaired astrocyte function and gcpii upregulation in activated microglia. |
2018-02-27 |
2023-08-13 |
rabbit |
| Rosario Gajardo-Gómez, Valeria C Labra, Carola J Maturana, Kenji F Shoji, Cristian A Santibañez, Juan C Sáez, Christian Giaume, Juan A Orellan. Cannabinoids prevent the amyloid β-induced activation of astroglial hemichannels: A neuroprotective mechanism. Glia. vol 65. issue 1. 2018-02-01. PMID:27757991. |
moreover, cbs fully abolished the aβ-induced release of excitotoxic glutamate and atp associated to astrocyte cx43 hemichannel activity, as well as neuronal damage in hippocampal slices exposed to aβ. |
2018-02-01 |
2023-08-13 |
Not clear |
| Fernanda Hansen, Fabiana Galland, Franciane Lirio, Daniela Fraga de Souza, Carollina Da Ré, Rafaela Ferreira Pacheco, Adriana Fernanda Vizuete, André Quincozes-Santos, Marina Concli Leite, Carlos-Alberto Gonçalve. Methylglyoxal Induces Changes in the Glyoxalase System and Impairs Glutamate Uptake Activity in Primary Astrocytes. Oxidative medicine and cellular longevity. vol 2017. 2018-01-31. PMID:28685011. |
thus, our data reinforce the idea that astrocyte viability depends on gap junctions and that the impairment induced by mg involves glutamate excitotoxicity. |
2018-01-31 |
2023-08-13 |
Not clear |
| Julia Langer, Niklas J Gerkau, Amin Derouiche, Christian Kleinhans, Behrouz Moshrefi-Ravasdjani, Michaela Fredrich, Karl W Kafitz, Gerald Seifert, Christian Steinhäuser, Christine R Ros. Rapid sodium signaling couples glutamate uptake to breakdown of ATP in perivascular astrocyte endfeet. Glia. vol 65. issue 2. 2018-01-12. PMID:27785828. |
rapid sodium signaling couples glutamate uptake to breakdown of atp in perivascular astrocyte endfeet. |
2018-01-12 |
2023-08-13 |
mouse |
| Blandine Madji Hounoum, Sylvie Mavel, Emmanuelle Coque, Franck Patin, Patrick Vourc'h, Sylviane Marouillat, Lydie Nadal-Desbarats, Patrick Emond, Philippe Corcia, Christian R Andres, Cédric Raoul, Hélène Blasc. Wildtype motoneurons, ALS-Linked SOD1 mutation and glutamate profoundly modify astrocyte metabolism and lactate shuttling. Glia. vol 65. issue 4. 2018-01-12. PMID:28139855. |
wildtype motoneurons, als-linked sod1 mutation and glutamate profoundly modify astrocyte metabolism and lactate shuttling. |
2018-01-12 |
2023-08-13 |
Not clear |
| Blandine Madji Hounoum, Sylvie Mavel, Emmanuelle Coque, Franck Patin, Patrick Vourc'h, Sylviane Marouillat, Lydie Nadal-Desbarats, Patrick Emond, Philippe Corcia, Christian R Andres, Cédric Raoul, Hélène Blasc. Wildtype motoneurons, ALS-Linked SOD1 mutation and glutamate profoundly modify astrocyte metabolism and lactate shuttling. Glia. vol 65. issue 4. 2018-01-12. PMID:28139855. |
sod1 astrocytes exposed to glutamate revealed a significant modification of the astrocyte metabolic fingerprint. |
2018-01-12 |
2023-08-13 |
Not clear |
| Gilbert Aaron Lee, Yein-Gei Lai, Ray-Jade Chen, Nan-Shih Lia. Interleukin 15 activates Akt to protect astrocytes from oxygen glucose deprivation-induced cell death. Cytokine. vol 92. 2018-01-05. PMID:28110119. |
since astrocytes promote neuron survival under cerebral ischemia by buffering excess extracellular glutamate and producing growth factors, recovery of astrocyte function could be of benefit for stroke therapy. |
2018-01-05 |
2023-08-13 |
Not clear |
| Anjana Bali, Amteshwar Singh Jagg. Angiotensin II-triggered kinase signaling cascade in the central nervous system. Reviews in the neurosciences. vol 27. issue 3. 2018-01-02. PMID:26574890. |
these signaling cascades lead to glutamate excitotoxicity, apoptosis, cerebral infarction, astrocyte proliferation, nociception, neuroinflammation, and progression of other neurological disorders. |
2018-01-02 |
2023-08-13 |
Not clear |
| Sana Al Awabdh, Swati Gupta-Agarwal, David F Sheehan, James Muir, Rosalind Norkett, Alison E Twelvetrees, Lewis D Griffin, Josef T Kittle. Neuronal activity mediated regulation of glutamate transporter GLT-1 surface diffusion in rat astrocytes in dissociated and slice cultures. Glia. vol 64. issue 7. 2018-01-02. PMID:27189737. |
fluorescence recovery after photobleaching and single particle tracking using quantum dots revealed that clustered glt-1 is more stable than diffuse glt-1 and that glutamate increases glt-1 surface diffusion in the astrocyte membrane. |
2018-01-02 |
2023-08-13 |
rat |
| Erica Zamberletti, Marina Gabaglio, Massimo Grilli, Pamela Prini, Alberto Catanese, Anna Pittaluga, Mario Marchi, Tiziana Rubino, Daniela Parolar. Long-term hippocampal glutamate synapse and astrocyte dysfunctions underlying the altered phenotype induced by adolescent THC treatment in male rats. Pharmacological research. vol 111. 2017-12-25. PMID:27422357. |
long-term hippocampal glutamate synapse and astrocyte dysfunctions underlying the altered phenotype induced by adolescent thc treatment in male rats. |
2017-12-25 |
2023-08-13 |
rat |
| Sinifunanya E Nwaobi, Vishnu A Cuddapah, Kelsey C Patterson, Anita C Randolph, Michelle L Olse. The role of glial-specific Kir4.1 in normal and pathological states of the CNS. Acta neuropathologica. vol 132. issue 1. 2017-12-04. PMID:26961251. |
in glia, kir4.1 is implicated in several functions including extracellular k(+) homeostasis, maintenance of astrocyte resting membrane potential, cell volume regulation, and facilitation of glutamate uptake. |
2017-12-04 |
2023-08-13 |
mouse |
| Li Ouyang, Yueyang Tian, Yun Bao, Huijuan Xu, Jiaoyan Cheng, Bingyu Wang, Yao Shen, Zhong Chen, Jianxin Ly. Carnosine decreased neuronal cell death through targeting glutamate system and astrocyte mitochondrial bioenergetics in cultured neuron/astrocyte exposed to OGD/recovery. Brain research bulletin. vol 124. 2017-10-26. PMID:27040711. |
carnosine decreased neuronal cell death through targeting glutamate system and astrocyte mitochondrial bioenergetics in cultured neuron/astrocyte exposed to ogd/recovery. |
2017-10-26 |
2023-08-13 |
human |
| Li Lu, Guangru Zhang, Chunli Song, Xuexi Wang, Weina Qian, Zhuanling Wang, Yanan Liu, Sheng Gong, Shuning Zho. Arachidonic acid has protective effects on oxygen-glucose deprived astrocytes mediated through enhancement of potassium channel TREK-1 activity. Neuroscience letters. vol 636. 2017-10-24. PMID:27865879. |
here, we assessed the effects of 3-30μm aa on astrocyte apoptosis, glutamate uptake, and expression of the astrocytic glutamate transporter 1 (glt-1) and trek-1 under different conditions. |
2017-10-24 |
2023-08-13 |
Not clear |
| Jason G Kilian, Heng-Wei Hsu, Kenneth Mata, Fred W Wolf, Masashi Kitazaw. Astrocyte transport of glutamate and neuronal activity reciprocally modulate tau pathology in Drosophila. Neuroscience. vol 348. 2017-09-26. PMID:28215745. |
astrocyte transport of glutamate and neuronal activity reciprocally modulate tau pathology in drosophila. |
2017-09-26 |
2023-08-13 |
mouse |
| Christopher I Ugbode, Imogen Smith, Benjamin J Whalley, Warren D Hirst, Marcus Rattra. Sonic hedgehog signalling mediates astrocyte crosstalk with neurons to confer neuroprotection. Journal of neurochemistry. vol 142. issue 3. 2017-09-21. PMID:28485896. |
these changes are accompanied by decreases in the major astrocyte glutamate transporter-1 and the astrocyte intermediate filament protein glial fibrillary acidic protein. |
2017-09-21 |
2023-08-13 |
mouse |
| Sun Kwang Kim, Hideaki Hayashi, Tatsuya Ishikawa, Keisuke Shibata, Eiji Shigetomi, Youichi Shinozaki, Hiroyuki Inada, Seung Eon Roh, Sang Jeong Kim, Gihyun Lee, Hyunsu Bae, Andrew J Moorhouse, Katsuhiko Mikoshiba, Yugo Fukazawa, Schuichi Koizumi, Junichi Nabekur. Cortical astrocytes rewire somatosensory cortical circuits for peripheral neuropathic pain. The Journal of clinical investigation. vol 126. issue 5. 2017-08-31. PMID:27064281. |
this s1 astrocyte reactivation was evident only during the first week after injury and correlated with the temporal changes in s1 extracellular glutamate levels and dendritic spine turnover. |
2017-08-31 |
2023-08-13 |
Not clear |
| Sarah E MacNamee, Kendra E Liu, Stephan Gerhard, Cathy T Tran, Richard D Fetter, Albert Cardona, Leslie P Tolbert, Lynne A Olan. Astrocytic glutamate transport regulates a Drosophila CNS synapse that lacks astrocyte ensheathment. The Journal of comparative neurology. vol 524. issue 10. 2017-08-30. PMID:27073064. |
astrocytic glutamate transport regulates a drosophila cns synapse that lacks astrocyte ensheathment. |
2017-08-30 |
2023-08-13 |
drosophila_melanogaster |
| De-Hyung Lee, Silvia Seubert, Konstantin Huhn, Lukas Brecht, Caroline Rötger, Anne Waschbisch, Johannes Schlachetzki, Alice Klausmeyer, Arthur Melms, Stefan Wiese, Jürgen Winkler, Ralf A Linke. Fingolimod effects in neuroinflammation: Regulation of astroglial glutamate transporters? PloS one. vol 12. issue 3. 2017-08-30. PMID:28273090. |
in astrocyte cell culture, the addition of pro-inflammatory cytokines led to a significant downregulation of glutamate transporters glutamate transporter-1 (slc1a2/slc1a2) and glutamate aspartate transporter (slc1a3/slc1a3) expression on the mrna or protein level. |
2017-08-30 |
2023-08-13 |
Not clear |
| Markel Olabarria, James E Goldma. Disorders of Astrocytes: Alexander Disease as a Model. Annual review of pathology. vol 12. 2017-08-17. PMID:28135564. |
the accumulation of extremely large amounts of gfap causes many molecular changes in astrocytes, including proteasome inhibition, stress kinase activation, mechanistic target of rapamycin (mtor) activation, loss of glutamate and potassium buffering capacity, loss of astrocyte coupling, and changes in cell morphology. |
2017-08-17 |
2023-08-13 |
Not clear |