| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiang Ye, Yu Zhang, Qiping Xu, Honghua Zheng, Xiaoyan Wu, Jinhua Qiu, Zhou Zhang, Wei Wang, Yiming Shao, Hui Qin Xin. HIV-1 Tat inhibits EAAT-2 through AEG-1 upregulation in models of HIV-associated neurocognitive disorder. Oncotarget. vol 8. issue 24. 2018-05-24. PMID:28404980. |
during hiv-associated neurocognitive disorder (hand), decreasing in excitatory amino acid transporter 2 (eaat-2) in astrocyte plasma membranes leads to elevated levels of extracellular glutamate and, in turn, neuronal apoptosis. |
2018-05-24 |
2023-08-13 |
Not clear |
| Jens Velde Andersen, Laura Frendrup McNair, Arne Schousboe, Helle Sønderby Waagepeterse. Specificity of exogenous acetate and glutamate as astrocyte substrates examined in acute brain slices from female mice using methionine sulfoximine (MSO) to inhibit glutamine synthesis. Journal of neuroscience research. vol 95. issue 11. 2018-05-18. PMID:28244146. |
specificity of exogenous acetate and glutamate as astrocyte substrates examined in acute brain slices from female mice using methionine sulfoximine (mso) to inhibit glutamine synthesis. |
2018-05-18 |
2023-08-13 |
mouse |
| Kristina Sakers, Allison M Lake, Rohan Khazanchi, Rebecca Ouwenga, Michael J Vasek, Adish Dani, Joseph D Doughert. Astrocytes locally translate transcripts in their peripheral processes. Proceedings of the National Academy of Sciences of the United States of America. vol 114. issue 19. 2018-04-24. PMID:28439016. |
computational analyses indicate that astrocyte-localized translation is both sequence-dependent and enriched for particular biological functions, such as fatty acid synthesis, and for pathways consistent with known roles for astrocyte processes, such as gaba and glutamate metabolism. |
2018-04-24 |
2023-08-13 |
Not clear |
| Hamid Kasnavi Yazdi, Mohammad Fazilati, Raheleh Rahbarian, Gholamhossein Riazi, Habibollah Naze. Aqueous extract of Launaea acanthodes induces glutamate uptake and GABA release in astrocyte cell culture via a ROS scavenging mediated process. Journal of chemical neuroanatomy. vol 82. 2018-03-19. PMID:28238867. |
aqueous extract of launaea acanthodes induces glutamate uptake and gaba release in astrocyte cell culture via a ros scavenging mediated process. |
2018-03-19 |
2023-08-13 |
Not clear |
| Thomas R Murphy, Devin K Binder, Todd A Fiacc. Turning down the volume: Astrocyte volume change in the generation and termination of epileptic seizures. Neurobiology of disease. vol 104. 2018-03-19. PMID:28438505. |
one of the proposed mechanisms for astrocyte involvement in seizures is astrocyte swelling, which may promote pathological neuronal firing and synchrony through reduction of the extracellular space and elevated glutamate concentrations. |
2018-03-19 |
2023-08-13 |
Not clear |
| Hui Wang, Shiqi Wang, Kang Zhang, Hua Wang, Liting Lan, Xiaoyun Ma, Xiaoyan Liu, Shuzhuo Zhang, Jianquan Zheng, Xiaoli Wei, Haitao Ya. Aquaporin 4 Forms a Macromolecular Complex with Glutamate Transporter 1 and Mu Opioid Receptor in Astrocytes and Participates in Morphine Dependence. Journal of molecular neuroscience : MN. vol 62. issue 1. 2018-03-06. PMID:28341892. |
these findings may help to reveal the mechanism that aqp4, glt-1, and mor form protein complex and participate in morphine dependence, and deeply understand the reason that aqp4 deficiency maintains extracellular glutamate homeostasis and attenuates morphine dependence, moreover emphasizes the function of astrocyte in morphine dependence. |
2018-03-06 |
2023-08-13 |
Not clear |
| Zhi Zhang, Bassam Bassam, Ajit G Thomas, Monica Williams, Jinhuan Liu, Elizabeth Nance, Camilo Rojas, Barbara S Slusher, Sujatha Kanna. Maternal inflammation leads to impaired glutamate homeostasis and up-regulation of glutamate carboxypeptidase II in activated microglia in the fetal/newborn rabbit brain. Neurobiology of disease. vol 94. 2018-02-27. PMID:27326668. |
in this study, we assessed the effect of maternal inflammation on key components of the glutamate pathway and its relationship to astrocyte and microglial activation in the fetal and neonatal new zealand white rabbit brain. |
2018-02-27 |
2023-08-13 |
rabbit |
| Zhi Zhang, Bassam Bassam, Ajit G Thomas, Monica Williams, Jinhuan Liu, Elizabeth Nance, Camilo Rojas, Barbara S Slusher, Sujatha Kanna. Maternal inflammation leads to impaired glutamate homeostasis and up-regulation of glutamate carboxypeptidase II in activated microglia in the fetal/newborn rabbit brain. Neurobiology of disease. vol 94. 2018-02-27. PMID:27326668. |
these results suggest that maternal intrauterine endotoxin exposure results in early onset and long-lasting dysregulation of glutamate homeostasis, which may be mediated by impaired astrocyte function and gcpii upregulation in activated microglia. |
2018-02-27 |
2023-08-13 |
rabbit |
| Rosario Gajardo-Gómez, Valeria C Labra, Carola J Maturana, Kenji F Shoji, Cristian A Santibañez, Juan C Sáez, Christian Giaume, Juan A Orellan. Cannabinoids prevent the amyloid β-induced activation of astroglial hemichannels: A neuroprotective mechanism. Glia. vol 65. issue 1. 2018-02-01. PMID:27757991. |
moreover, cbs fully abolished the aβ-induced release of excitotoxic glutamate and atp associated to astrocyte cx43 hemichannel activity, as well as neuronal damage in hippocampal slices exposed to aβ. |
2018-02-01 |
2023-08-13 |
Not clear |
| Fernanda Hansen, Fabiana Galland, Franciane Lirio, Daniela Fraga de Souza, Carollina Da Ré, Rafaela Ferreira Pacheco, Adriana Fernanda Vizuete, André Quincozes-Santos, Marina Concli Leite, Carlos-Alberto Gonçalve. Methylglyoxal Induces Changes in the Glyoxalase System and Impairs Glutamate Uptake Activity in Primary Astrocytes. Oxidative medicine and cellular longevity. vol 2017. 2018-01-31. PMID:28685011. |
thus, our data reinforce the idea that astrocyte viability depends on gap junctions and that the impairment induced by mg involves glutamate excitotoxicity. |
2018-01-31 |
2023-08-13 |
Not clear |
| Julia Langer, Niklas J Gerkau, Amin Derouiche, Christian Kleinhans, Behrouz Moshrefi-Ravasdjani, Michaela Fredrich, Karl W Kafitz, Gerald Seifert, Christian Steinhäuser, Christine R Ros. Rapid sodium signaling couples glutamate uptake to breakdown of ATP in perivascular astrocyte endfeet. Glia. vol 65. issue 2. 2018-01-12. PMID:27785828. |
rapid sodium signaling couples glutamate uptake to breakdown of atp in perivascular astrocyte endfeet. |
2018-01-12 |
2023-08-13 |
mouse |
| Blandine Madji Hounoum, Sylvie Mavel, Emmanuelle Coque, Franck Patin, Patrick Vourc'h, Sylviane Marouillat, Lydie Nadal-Desbarats, Patrick Emond, Philippe Corcia, Christian R Andres, Cédric Raoul, Hélène Blasc. Wildtype motoneurons, ALS-Linked SOD1 mutation and glutamate profoundly modify astrocyte metabolism and lactate shuttling. Glia. vol 65. issue 4. 2018-01-12. PMID:28139855. |
wildtype motoneurons, als-linked sod1 mutation and glutamate profoundly modify astrocyte metabolism and lactate shuttling. |
2018-01-12 |
2023-08-13 |
Not clear |
| Blandine Madji Hounoum, Sylvie Mavel, Emmanuelle Coque, Franck Patin, Patrick Vourc'h, Sylviane Marouillat, Lydie Nadal-Desbarats, Patrick Emond, Philippe Corcia, Christian R Andres, Cédric Raoul, Hélène Blasc. Wildtype motoneurons, ALS-Linked SOD1 mutation and glutamate profoundly modify astrocyte metabolism and lactate shuttling. Glia. vol 65. issue 4. 2018-01-12. PMID:28139855. |
sod1 astrocytes exposed to glutamate revealed a significant modification of the astrocyte metabolic fingerprint. |
2018-01-12 |
2023-08-13 |
Not clear |
| Gilbert Aaron Lee, Yein-Gei Lai, Ray-Jade Chen, Nan-Shih Lia. Interleukin 15 activates Akt to protect astrocytes from oxygen glucose deprivation-induced cell death. Cytokine. vol 92. 2018-01-05. PMID:28110119. |
since astrocytes promote neuron survival under cerebral ischemia by buffering excess extracellular glutamate and producing growth factors, recovery of astrocyte function could be of benefit for stroke therapy. |
2018-01-05 |
2023-08-13 |
Not clear |
| Anjana Bali, Amteshwar Singh Jagg. Angiotensin II-triggered kinase signaling cascade in the central nervous system. Reviews in the neurosciences. vol 27. issue 3. 2018-01-02. PMID:26574890. |
these signaling cascades lead to glutamate excitotoxicity, apoptosis, cerebral infarction, astrocyte proliferation, nociception, neuroinflammation, and progression of other neurological disorders. |
2018-01-02 |
2023-08-13 |
Not clear |
| Sana Al Awabdh, Swati Gupta-Agarwal, David F Sheehan, James Muir, Rosalind Norkett, Alison E Twelvetrees, Lewis D Griffin, Josef T Kittle. Neuronal activity mediated regulation of glutamate transporter GLT-1 surface diffusion in rat astrocytes in dissociated and slice cultures. Glia. vol 64. issue 7. 2018-01-02. PMID:27189737. |
fluorescence recovery after photobleaching and single particle tracking using quantum dots revealed that clustered glt-1 is more stable than diffuse glt-1 and that glutamate increases glt-1 surface diffusion in the astrocyte membrane. |
2018-01-02 |
2023-08-13 |
rat |
| Erica Zamberletti, Marina Gabaglio, Massimo Grilli, Pamela Prini, Alberto Catanese, Anna Pittaluga, Mario Marchi, Tiziana Rubino, Daniela Parolar. Long-term hippocampal glutamate synapse and astrocyte dysfunctions underlying the altered phenotype induced by adolescent THC treatment in male rats. Pharmacological research. vol 111. 2017-12-25. PMID:27422357. |
long-term hippocampal glutamate synapse and astrocyte dysfunctions underlying the altered phenotype induced by adolescent thc treatment in male rats. |
2017-12-25 |
2023-08-13 |
rat |
| Sinifunanya E Nwaobi, Vishnu A Cuddapah, Kelsey C Patterson, Anita C Randolph, Michelle L Olse. The role of glial-specific Kir4.1 in normal and pathological states of the CNS. Acta neuropathologica. vol 132. issue 1. 2017-12-04. PMID:26961251. |
in glia, kir4.1 is implicated in several functions including extracellular k(+) homeostasis, maintenance of astrocyte resting membrane potential, cell volume regulation, and facilitation of glutamate uptake. |
2017-12-04 |
2023-08-13 |
mouse |
| Li Ouyang, Yueyang Tian, Yun Bao, Huijuan Xu, Jiaoyan Cheng, Bingyu Wang, Yao Shen, Zhong Chen, Jianxin Ly. Carnosine decreased neuronal cell death through targeting glutamate system and astrocyte mitochondrial bioenergetics in cultured neuron/astrocyte exposed to OGD/recovery. Brain research bulletin. vol 124. 2017-10-26. PMID:27040711. |
carnosine decreased neuronal cell death through targeting glutamate system and astrocyte mitochondrial bioenergetics in cultured neuron/astrocyte exposed to ogd/recovery. |
2017-10-26 |
2023-08-13 |
human |
| Li Lu, Guangru Zhang, Chunli Song, Xuexi Wang, Weina Qian, Zhuanling Wang, Yanan Liu, Sheng Gong, Shuning Zho. Arachidonic acid has protective effects on oxygen-glucose deprived astrocytes mediated through enhancement of potassium channel TREK-1 activity. Neuroscience letters. vol 636. 2017-10-24. PMID:27865879. |
here, we assessed the effects of 3-30μm aa on astrocyte apoptosis, glutamate uptake, and expression of the astrocytic glutamate transporter 1 (glt-1) and trek-1 under different conditions. |
2017-10-24 |
2023-08-13 |
Not clear |