| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kiyoshi Oomagari, Bruno Buisson, Aline Dumuis, Joël Bockaert, Jean-Philippe Pi. Effect of Glutamate and Ionomycin on the Release of Arachidonic Acid, Prostaglandins and HETEs from Cultured Neurons and Astrocytes. The European journal of neuroscience. vol 3. issue 10. 2019-11-20. PMID:12106250. |
in contrast, in astrocyte cultures, ionomycin (but not glutamate) strongly stimulated the release of pgs and hetes as well as ara. |
2019-11-20 |
2023-08-12 |
mouse |
| Victoria Cano, Ismael Valladolid-Acebes, Francisco Hernández-Nuño, Beatriz Merino, Nuria Del Olmo, Julie A Chowen, Mariano Ruiz-Gay. Morphological changes in glial fibrillary acidic protein immunopositive astrocytes in the hippocampus of dietary-induced obese mice. Neuroreport. vol 25. issue 11. 2019-11-20. PMID:24911388. |
we have analyzed astrocyte morphology and density by glial fibrillary acidic protein immunohistochemistry, as well as the expression of the glutamate transporters, glt-1 (glutamate transporter type-1), and glast (astrocyte glutamate transporter), in the ca3 area of the hippocampus. |
2019-11-20 |
2023-08-13 |
mouse |
| Gaëlle Champeil-Potokar, Marie Hennebelle, Alizée Latour, Sylvie Vancassel, Isabelle Deni. Docosahexaenoic acid (DHA) prevents corticosterone-induced changes in astrocyte morphology and function. Journal of neurochemistry. vol 136. issue 6. 2019-11-20. PMID:26709611. |
corticosterone stimulated astrocyte glutamate recycling by increasing glutamate uptake and glutamine synthetase (gs), and altered the astrocyte cytoskeleton. |
2019-11-20 |
2023-08-13 |
rat |
| Elisabeth Hansso. Long-term pain, neuroinflammation and glial activation. Scandinavian journal of pain. vol 1. issue 2. 2019-11-20. PMID:29913949. |
increased release of glutamate and atp leads to disturbances in ca2+ signalling, increased production of cytokines and free radicals, attenuation of the astrocyte glutamate transport capacity, and conformational changes in the astrocytic cytoskeleton, the actin filaments, which can lead to formation and rebuilding of new synapses. |
2019-11-20 |
2023-08-13 |
Not clear |
| Simone Pelassa, Diego Guidolin, Arianna Venturini, Monica Averna, Giulia Frumento, Letizia Campanini, Rosa Bernardi, Pietro Cortelli, Giovanna Calandra Buonaura, Guido Maura, Luigi F Agnati, Chiara Cervetto, Manuela Marcol. A2A-D2 Heteromers on Striatal Astrocytes: Biochemical and Biophysical Evidence. International journal of molecular sciences. vol 20. issue 10. 2019-11-12. PMID:31109007. |
our previous findings indicate that a2a and d2 receptors are co-expressed on adult rat striatal astrocytes and on the astrocyte processes, and that a2a-d2 receptor⁻receptor interaction can control the release of glutamate from the processes. |
2019-11-12 |
2023-08-13 |
rat |
| Chun-Shu Piao, Ashley L Holloway, Sue Hong-Routson, Mark S Wainwrigh. Depression following traumatic brain injury in mice is associated with down-regulation of hippocampal astrocyte glutamate transporters by thrombin. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 39. issue 1. 2019-11-04. PMID:29135354. |
depression following traumatic brain injury in mice is associated with down-regulation of hippocampal astrocyte glutamate transporters by thrombin. |
2019-11-04 |
2023-08-13 |
mouse |
| Chun-Shu Piao, Ashley L Holloway, Sue Hong-Routson, Mark S Wainwrigh. Depression following traumatic brain injury in mice is associated with down-regulation of hippocampal astrocyte glutamate transporters by thrombin. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 39. issue 1. 2019-11-04. PMID:29135354. |
these results identify a novel mechanism by which tbi results in down-regulation of astrocyte glutamate transporters and implicate astrocyte and glutamate transporter dysfunction in depression following tbi. |
2019-11-04 |
2023-08-13 |
mouse |
| Megan E Bosch, Tammy Kielia. Astrocytes in juvenile neuronal ceroid lipofuscinosis (CLN3) display metabolic and calcium signaling abnormalities. Journal of neurochemistry. vol 148. issue 5. 2019-10-28. PMID:29964296. |
neuronal loss is thought to occur, in part, via glutamate excitotoxicity; however, little is known about astrocyte glutamate regulation in jncl. |
2019-10-28 |
2023-08-13 |
Not clear |
| Hyun Geun Shim, Sung-Soo Jang, Seung Ha Kim, Eun Mi Hwang, Joo Ok Min, Hye Yun Kim, Yoo Sung Kim, Changhyeon Ryu, Geehoon Chung, YoungSoo Kim, Bo-Eun Yoon, Sang Jeong Ki. TNF-α increases the intrinsic excitability of cerebellar Purkinje cells through elevating glutamate release in Bergmann Glia. Scientific reports. vol 8. issue 1. 2019-10-21. PMID:30072733. |
in addition, we measured the concentration of glutamate derived from dissociated cerebellar cortical astrocyte cultures treated with tnf-α and observed a progressive increase of glutamate in a time-dependent manner. |
2019-10-21 |
2023-08-13 |
human |
| Michael D Scofiel. Exploring the Role of Astroglial Glutamate Release and Association With Synapses in Neuronal Function and Behavior. Biological psychiatry. vol 84. issue 11. 2019-10-08. PMID:29258653. |
however, data from animal models of addiction demonstrate that a variety of drug-induced molecular adaptations responsible for relapse vulnerability take place in astrocyte systems that regulate glutamate uptake and release. |
2019-10-08 |
2023-08-13 |
Not clear |
| Michael D Scofiel. Exploring the Role of Astroglial Glutamate Release and Association With Synapses in Neuronal Function and Behavior. Biological psychiatry. vol 84. issue 11. 2019-10-08. PMID:29258653. |
further, i compile evidence regarding astrocyte glutamate release as well as astrocyte association with synapses with respect to the impact of these cellular phenomena in shaping synaptic transmission. |
2019-10-08 |
2023-08-13 |
Not clear |
| Theresa S Rimmele, Haissa de Castro Abrantes, Joel Wellbourne-Wood, Sylvain Lengacher, Jean-Yves Chatto. Extracellular Potassium and Glutamate Interact To Modulate Mitochondria in Astrocytes. ACS chemical neuroscience. vol 9. issue 8. 2019-10-03. PMID:29741354. |
whereas astrocyte glutamate uptake causes cytosolic and mitochondrial acidification, extracellular potassium induces bicarbonate-dependent cellular alkalinization. |
2019-10-03 |
2023-08-13 |
Not clear |
| Philippine C Geiszler, Aslihan Ugun-Klusek, Karen Lawler, Marie-Christine Pardon, Ding Yuchun, Li Bai, Clare A Daykin, Dorothee P Auer, Lynn Bedfor. Dynamic metabolic patterns tracking neurodegeneration and gliosis following 26S proteasome dysfunction in mouse forebrain neurons. Scientific reports. vol 8. issue 1. 2019-09-23. PMID:29555943. |
our results extend the limited understanding of metabolite changes associated with gliosis and provide evidence that changes in glutamate homeostasis and lactate may correlate with astrocyte activation and have biomarker potential for tracking neuroinflammation. |
2019-09-23 |
2023-08-13 |
mouse |
| Caroline Zanotto, Fernanda Hansen, Fabiana Galland, Cristiane Batassini, Bárbara Carolina Federhen, Vanessa Fernanda da Silva, Marina Concli Leite, Patrícia Nardin, Carlos-Alberto Gonçalve. Glutamatergic Alterations in STZ-Induced Diabetic Rats Are Reversed by Exendin-4. Molecular neurobiology. vol 56. issue 5. 2019-08-13. PMID:30145785. |
ex-4 abrogated the decrease in glutamate uptake and glun1 content caused by methylglyoxal (mg) in hippocampal slices, in addition to leading to an increase in glutamate uptake in astrocyte culture cells and hippocampal slices under basal conditions. |
2019-08-13 |
2023-08-13 |
rat |
| Inés Juaristi, Irene Llorente-Folch, Jorgina Satrústegui, Araceli Del Arc. Extracellular ATP and glutamate drive pyruvate production and energy demand to regulate mitochondrial respiration in astrocytes. Glia. vol 67. issue 4. 2019-06-11. PMID:30623988. |
this study addresses the role of respiration and calcium regulation of respiration as part of the astrocyte response to the workloads caused by extracellular atp and glutamate. |
2019-06-11 |
2023-08-13 |
Not clear |
| Amit Zeisel, Hannah Hochgerner, Peter Lönnerberg, Anna Johnsson, Fatima Memic, Job van der Zwan, Martin Häring, Emelie Braun, Lars E Borm, Gioele La Manno, Simone Codeluppi, Alessandro Furlan, Kawai Lee, Nathan Skene, Kenneth D Harris, Jens Hjerling-Leffler, Ernest Arenas, Patrik Ernfors, Ulrika Marklund, Sten Linnarsso. Molecular Architecture of the Mouse Nervous System. Cell. vol 174. issue 4. 2019-05-20. PMID:30096314. |
we discovered seven distinct, regionally restricted astrocyte types that obeyed developmental boundaries and correlated with the spatial distribution of key glutamate and glycine neurotransmitters. |
2019-05-20 |
2023-08-13 |
mouse |
| Ljiljana Nikolic, Weida Shen, Paola Nobili, Anaïs Virenque, Lauriane Ulmann, Etienne Audina. Blocking TNFα-driven astrocyte purinergic signaling restores normal synaptic activity during epileptogenesis. Glia. vol 66. issue 12. 2019-04-15. PMID:30394583. |
epileptic seizures are also accompanied by increase of tumor necrosis factor alpha (tnfα), a cytokine involved in the regulation of astrocyte glutamate release. |
2019-04-15 |
2023-08-13 |
Not clear |
| Ljiljana Nikolic, Weida Shen, Paola Nobili, Anaïs Virenque, Lauriane Ulmann, Etienne Audina. Blocking TNFα-driven astrocyte purinergic signaling restores normal synaptic activity during epileptogenesis. Glia. vol 66. issue 12. 2019-04-15. PMID:30394583. |
here we tested whether tnfα controls abnormal astrocyte glutamate signaling in epilepsy and through which mechanism. |
2019-04-15 |
2023-08-13 |
Not clear |
| James Johnson, Edward Pajarillo, Pratap Karki, Judong Kim, Deok-Soo Son, Michael Aschner, Eunsook Le. Valproic acid attenuates manganese-induced reduction in expression of GLT-1 and GLAST with concomitant changes in murine dopaminergic neurotoxicity. Neurotoxicology. vol 67. 2019-04-08. PMID:29778792. |
in the present study, we investigated if vpa attenuated mn-induced dopaminergic neurotoxicity and the possible mechanisms involved in vpa's neuroprotection, focusing on modulation of astrocytic glutamate transporters (glutamate aspartate transporter, glast and glutamate transporter 1, glt-1) and histone acetylation in h4 astrocyte culture and mouse models. |
2019-04-08 |
2023-08-13 |
mouse |
| James Johnson, Edward Pajarillo, Pratap Karki, Judong Kim, Deok-Soo Son, Michael Aschner, Eunsook Le. Valproic acid attenuates manganese-induced reduction in expression of GLT-1 and GLAST with concomitant changes in murine dopaminergic neurotoxicity. Neurotoxicology. vol 67. 2019-04-08. PMID:29778792. |
the results showed that vpa increased promoter activity, mrna/protein levels of glast/glt-1 and glutamate uptake, and reversed mn-reduced glast/glt-1 in in vitro astrocyte cultures. |
2019-04-08 |
2023-08-13 |
mouse |