| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Inés Juaristi, Irene Llorente-Folch, Jorgina Satrústegui, Araceli Del Arc. Extracellular ATP and glutamate drive pyruvate production and energy demand to regulate mitochondrial respiration in astrocytes. Glia. vol 67. issue 4. 2019-06-11. PMID:30623988. |
this study addresses the role of respiration and calcium regulation of respiration as part of the astrocyte response to the workloads caused by extracellular atp and glutamate. |
2019-06-11 |
2023-08-13 |
Not clear |
| Amit Zeisel, Hannah Hochgerner, Peter Lönnerberg, Anna Johnsson, Fatima Memic, Job van der Zwan, Martin Häring, Emelie Braun, Lars E Borm, Gioele La Manno, Simone Codeluppi, Alessandro Furlan, Kawai Lee, Nathan Skene, Kenneth D Harris, Jens Hjerling-Leffler, Ernest Arenas, Patrik Ernfors, Ulrika Marklund, Sten Linnarsso. Molecular Architecture of the Mouse Nervous System. Cell. vol 174. issue 4. 2019-05-20. PMID:30096314. |
we discovered seven distinct, regionally restricted astrocyte types that obeyed developmental boundaries and correlated with the spatial distribution of key glutamate and glycine neurotransmitters. |
2019-05-20 |
2023-08-13 |
mouse |
| Ljiljana Nikolic, Weida Shen, Paola Nobili, Anaïs Virenque, Lauriane Ulmann, Etienne Audina. Blocking TNFα-driven astrocyte purinergic signaling restores normal synaptic activity during epileptogenesis. Glia. vol 66. issue 12. 2019-04-15. PMID:30394583. |
epileptic seizures are also accompanied by increase of tumor necrosis factor alpha (tnfα), a cytokine involved in the regulation of astrocyte glutamate release. |
2019-04-15 |
2023-08-13 |
Not clear |
| Ljiljana Nikolic, Weida Shen, Paola Nobili, Anaïs Virenque, Lauriane Ulmann, Etienne Audina. Blocking TNFα-driven astrocyte purinergic signaling restores normal synaptic activity during epileptogenesis. Glia. vol 66. issue 12. 2019-04-15. PMID:30394583. |
here we tested whether tnfα controls abnormal astrocyte glutamate signaling in epilepsy and through which mechanism. |
2019-04-15 |
2023-08-13 |
Not clear |
| James Johnson, Edward Pajarillo, Pratap Karki, Judong Kim, Deok-Soo Son, Michael Aschner, Eunsook Le. Valproic acid attenuates manganese-induced reduction in expression of GLT-1 and GLAST with concomitant changes in murine dopaminergic neurotoxicity. Neurotoxicology. vol 67. 2019-04-08. PMID:29778792. |
in the present study, we investigated if vpa attenuated mn-induced dopaminergic neurotoxicity and the possible mechanisms involved in vpa's neuroprotection, focusing on modulation of astrocytic glutamate transporters (glutamate aspartate transporter, glast and glutamate transporter 1, glt-1) and histone acetylation in h4 astrocyte culture and mouse models. |
2019-04-08 |
2023-08-13 |
mouse |
| James Johnson, Edward Pajarillo, Pratap Karki, Judong Kim, Deok-Soo Son, Michael Aschner, Eunsook Le. Valproic acid attenuates manganese-induced reduction in expression of GLT-1 and GLAST with concomitant changes in murine dopaminergic neurotoxicity. Neurotoxicology. vol 67. 2019-04-08. PMID:29778792. |
the results showed that vpa increased promoter activity, mrna/protein levels of glast/glt-1 and glutamate uptake, and reversed mn-reduced glast/glt-1 in in vitro astrocyte cultures. |
2019-04-08 |
2023-08-13 |
mouse |
| JiaRui Zhang, YuXuan Wang, ZiHui Zheng, XiaoHe Sun, TingTing Chen, Chen Li, XiaoLong Zhang, Jun Gu. Intracellular ion and protein nanoparticle-induced osmotic pressure modify astrocyte swelling and brain edema in response to glutamate stimuli. Redox biology. vol 21. 2019-04-01. PMID:30685709. |
intracellular ion and protein nanoparticle-induced osmotic pressure modify astrocyte swelling and brain edema in response to glutamate stimuli. |
2019-04-01 |
2023-08-13 |
Not clear |
| Matthew Neal, Jie Luo, Dilshan S Harischandra, Richard Gordon, Souvarish Sarkar, Huajun Jin, Vellareddy Anantharam, Laurent Désaubry, Anumantha Kanthasamy, Arthi Kanthasam. Prokineticin-2 promotes chemotaxis and alternative A2 reactivity of astrocytes. Glia. vol 66. issue 10. 2019-03-18. PMID:30277602. |
pk2-induced astrocyte reactivity leads to an increase in antioxidant and anti-inflammatory proteins while increasing glutamate uptake, along with decreased inflammatory factors. |
2019-03-18 |
2023-08-13 |
mouse |
| Kivilcim Kilic, Hulya Karatas, Buket Dönmez-Demir, Emine Eren-Kocak, Yasemin Gursoy-Ozdemir, Alp Can, Jean-Marie Petit, Pierre J Magistretti, Turgay Dalkar. Inadequate brain glycogen or sleep increases spreading depression susceptibility. Annals of neurology. vol 83. issue 1. 2019-01-22. PMID:29244233. |
glycogen in astrocyte processes contributes to maintenance of low extracellular glutamate and k |
2019-01-22 |
2023-08-13 |
Not clear |
| Tara Deemyad, Joel Lüthi, Nelson Sprusto. Astrocytes integrate and drive action potential firing in inhibitory subnetworks. Nature communications. vol 9. issue 1. 2019-01-07. PMID:30337521. |
here we show that calcium signaling in an astrocytic network correlates with barrage firing; that active depolarization of astrocyte networks by chemical or optogenetic stimulation enhances; and that chelating internal calcium, inhibiting release from internal stores, or inhibiting gaba transporters or metabotropic glutamate receptors inhibits barrage firing. |
2019-01-07 |
2023-08-13 |
Not clear |
| Jiao Wang, Fangfang Zhou, Dong Wang, Jie Li, Dongfang Lu, Qian Li, Hong Zhou, Weihao Li, Qian Wang, Yiliu Wu, Jiang Xie, Tieqiao We. Interaction of DCF1 with ATP1B1 induces impairment in astrocyte structural plasticity via the P38 signaling pathway. Experimental neurology. vol 302. 2018-12-11. PMID:29337145. |
our data shed light on the possible mechanisms underlying changes in astrocyte morphology and provide new avenues for the exploration of proteins involved in glutamate release. |
2018-12-11 |
2023-08-13 |
mouse |
| Sukhee Cho, Allie K Muthukumar, Tobias Stork, Jaeda C Coutinho-Budd, Marc R Freema. Focal adhesion molecules regulate astrocyte morphology and glutamate transporters to suppress seizure-like behavior. Proceedings of the National Academy of Sciences of the United States of America. vol 115. issue 44. 2018-12-11. PMID:30327343. |
focal adhesion molecules regulate astrocyte morphology and glutamate transporters to suppress seizure-like behavior. |
2018-12-11 |
2023-08-13 |
Not clear |
| Amanda M Sweeney, Kelsey E Fleming, John P McCauley, Marvin F Rodriguez, Elliot T Martin, Alioscka A Sousa, Richard D Leapman, Annalisa Scimem. PAR1 activation induces rapid changes in glutamate uptake and astrocyte morphology. Scientific reports. vol 7. 2018-11-08. PMID:28256580. |
par1 activation induces rapid changes in glutamate uptake and astrocyte morphology. |
2018-11-08 |
2023-08-13 |
mouse |
| Chiara Cervetto, Arianna Venturini, Diego Guidolin, Guido Maura, Mario Passalacqua, Carlo Tacchetti, Pietro Cortelli, Susanna Genedani, Simona Candiani, Paola Ramoino, Simone Pelassa, Manuela Marcoli, Luigi F Agnat. Homocysteine and A2A-D2 Receptor-Receptor Interaction at Striatal Astrocyte Processes. Journal of molecular neuroscience : MN. vol 65. issue 4. 2018-11-08. PMID:30030763. |
we found that a2a and d2 receptors were co-expressed on vesicular glutamate transporter-1-positive astrocyte processes, and confirmed that a2a-d2 receptor-receptor interaction controlled glutamate release-assessed by measuring the [ |
2018-11-08 |
2023-08-13 |
rat |
| Qiong Wang, Zhen Wang, Yeye Tian, Huaqiu Zhang, Yongkang Fang, Zhiyuan Yu, Wei Wang, Minjie Xie, Fengfei Din. Inhibition of Astrocyte Connexin 43 Channels Facilitates the Differentiation of Oligodendrocyte Precursor Cells Under Hypoxic Conditions In Vitro. Journal of molecular neuroscience : MN. vol 64. issue 4. 2018-09-18. PMID:29623602. |
application of astrocytic cx43 blockers attenuated astrocyte activation, suppressed cx43 hemichannel uptake activity and glutamate release induced by hypoxia, as well as improved opc differentiation. |
2018-09-18 |
2023-08-13 |
Not clear |
| Mariko Kato Hayash. Structure-Function Relationship of Transporters in the Glutamate-Glutamine Cycle of the Central Nervous System. International journal of molecular sciences. vol 19. issue 4. 2018-09-11. PMID:29649168. |
glutamate taken up by astrocyte is converted to glutamine by glutamine synthetase and transported back to neurons through glutamine transporters on the plasma membranes of the astrocytes and then on neurons. |
2018-09-11 |
2023-08-13 |
Not clear |
| Ross Nortley, David Attwel. Control of brain energy supply by astrocytes. Current opinion in neurobiology. vol 47. 2018-07-27. PMID:29054039. |
controversy persists over whether lactate derived from astrocyte glycolysis is used to power oxidative phosphorylation in neurons, but astrocytes sustain neuronal atp production by recycling neurotransmitter glutamate that would otherwise need to be resynthesised from glucose, and by providing a short-term energy store in the form of glycogen that can be mobilised when neurons are active. |
2018-07-27 |
2023-08-13 |
Not clear |
| Behrouz Moshrefi-Ravasdjani, Evelyn L Hammel, Karl W Kafitz, Christine R Ros. Astrocyte Sodium Signalling and Panglial Spread of Sodium Signals in Brain White Matter. Neurochemical research. vol 42. issue 9. 2018-07-09. PMID:28214986. |
taken together, our results demonstrate that activation of sodium-dependent glutamate transporters induces sodium signals in white matter astrocytes, which spread within the astrocyte syncytium. |
2018-07-09 |
2023-08-13 |
mouse |
| Sarah Jolly, Narges Bazargani, Alejandra C Quiroga, Nigel P Pringle, David Attwell, William D Richardson, Huiliang L. G protein-coupled receptor 37-like 1 modulates astrocyte glutamate transporters and neuronal NMDA receptors and is neuroprotective in ischemia. Glia. vol 66. issue 1. 2018-07-02. PMID:28795439. |
g protein-coupled receptor 37-like 1 modulates astrocyte glutamate transporters and neuronal nmda receptors and is neuroprotective in ischemia. |
2018-07-02 |
2023-08-13 |
mouse |
| Fabiana Galland, Elisa Negri, Carollina Da Ré, Fernanda Fróes, Liliane Strapazzon, Maria Cristina Guerra, Lucas Silva Tortorelli, Carlos-Alberto Gonçalves, Marina Concli Leit. Hyperammonemia compromises glutamate metabolism and reduces BDNF in the rat hippocampus. Neurotoxicology. vol 62. 2018-05-30. PMID:28506823. |
hyperammonemia directly impaired astrocyte function, inducing a decrease in glutamate uptake and in the activity of glutamine synthetase, in turn altering the glutamine-glutamate cycle, glutamatergic neurotransmission and ammonia detoxification itself. |
2018-05-30 |
2023-08-13 |
rat |